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Medicinal plant cultivation is essentially a way of management so that a medicinal plant can bring high yields and good quality. This condition can occur if the plant can grow in a suitable environment, including commensurate soil fertility, and suitable climate with appropriate technology. One of the plants that can be developed vegetatively is the Orthosiphon stamineus Benth.s, which is very useful as a kidney medicine, for epilepsy, hepatitis, and gallstones. Orthosiphon stamineus Benth.s plant extract can also be used for anti-fungal, anti-bacterial, anti-allergic, anti-hypertensive, and anti-inflammatory purposes. The purpose of the study was to determine the effect of planting distance and dose of organic fertilization on the growth and production of stove purple flower Orthosiphon stamineus Benth.s. The research took place from July to October 2020 at the Experimental Garden of B2TP Lampung. Materials Orthosiphon stamineus Benth. stem cuttings, organic fertilizer (cow manure), water. Tools used were a hand tractor, Cultivator, hoe, scissors, meter, vernier, plastic basket, tray, and oven. This study used a Split plot Design with three replications. The treatment variables used were planting distance as the main plot consisting of 3 levels (0.4 mx0.4 m; 0.5 m x 0.4 m; and 0.6 m x 0.4 m). Then the dose of organic fertilizer as a subplot consisting of 4 levels (150 grams per plant, 300 grams per plant, 450 grams per plant, and 600 grams per plant). The experiment was repeated 3 times so that there were 36 experimental plots. The results of the analysis of variance for the production of Orthosiphon stamineus Benth. s. yields, there is an interaction of planting distance treatment and organic fertilizer dosing that gives significantly different results (p