1. Étiologies et pronostic des mégavessies de diagnostic prénatal selon l’âge de découverte. Étude rétrospective sur six années
- Author
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Peyrière, M.-P., Roth, P., Combourieu, D., Vavasseur, C., Bouvier, R., Guibaud, L., and Gaucherand, P.
- Subjects
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PRENATAL diagnosis , *MEDICAL imaging systems , *RETROSPECTIVE studies , *PROGNOSIS , *ETIOLOGY of diseases - Abstract
Abstract: Objectives: The purpose of this study is to describe the diagnosis, the care and the prognosis of the fetuses with an antenataly diagnosed megacystis. Patients and methods: Six year retrospective study about 46 cases of megacystis (26 diagnosed during 1st trimester; 14 during 2nd trimester; 9 during 3rd trimester) referred in the prenatal fetal medicine unit of the Femme–Mère-Enfant hospital in Lyon (France). Results: The main aetiology is urethral occlusion, particularly for megacystis discovered during the 1st and the 2nd trimesters. Twenty-two terminations of pregnancy were performed (47.8%) and 6 pregnancies arrested spontaneously (13%). Eighteen children were born alive, but 2 died in neonatal period. Finally, 16 children survived (34.8%). Chromosomal abnormalities are frequent (22%). Discussion and conclusion: Antenatal discovery of a megacystis is a complex situation, and often of poor fetal prognosis. It requires a multidisciplinary approach to allow the concerned couple to be determined on the best care of this pregnancy. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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