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Music therapy for premature babies in neonatal units: current approaches and practices. The practice of music therapy for premature newborns may question or divide the professionals working in neonate care. True, this care practice isn't well known, especially in France. The effective job of a music therapist, not yet state recognized, might be confusing for some: musician, activity leader in musical mediation, or even worst occult speaker bearer of bad news? Music therapy is far from those few pictures. In this article, we aim to present, through a largely qualitative approach, the current practices of music therapy, in three separate fields: neurology, physiology and behaviors, and psycho sociology. Differences between the use of live or recorded music, adjusted or not to the infant reactions, are analyzed. The advantages of a music therapy delivered by a professional music therapist are proved, especially in the field of neurodevelopment. [ABSTRACT FROM AUTHOR]

The discovery of the neuropeptide kisspeptin and of its role in the regulation of reproduction have been a breakthrough in our understanding of the physiological mechanisms mastering this physiological function. Several pharmacological and genetic approaches using animal models have shown that kisspeptin directly stimulates GnRH and consequently gonadotrophins secretion. The two main kisspeptin populations are located in the preoptic area and arcuate nucleus. These populations are the target of the positive and negative feedback of sexual hormones. Due to its central role in the stimulation of GnRH secretion, the effect of kisspeptin has been the focus of clinical studies evaluating its capacity to treat some reproductive pathologies. Promising results have been obtained for in vitro fertilization therapy and for the treatment of hypothalamic amenorrhea. Preliminary studies were also performed in patients affected by the polycystic ovary syndrome and by hypofertility due to type II diabetes. All together, these results show that the modulation of the kisspeptin system is a promising therapeutic opportunity. In the future, thanks to the creation of synthetic molecules capable to palliate some limitation of the endogenous molecules, clinical research based on the modulation of the kisspeptin system will certainly gain momentum. [ABSTRACT FROM AUTHOR]