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This paper considers the relations among L -fuzzy sets, rough sets and hyperring theory. Based on a complete residuated lattice, the concept of (invertible) L-fuzzy hyperideals of a hyperring is introduced and some related properties are presented. The notions of lower and upper L-fuzzy rough approximation operators with respect to an L-fuzzy hyperideal are provided and some significant properties of them are discussed. In addition, a new algebraic structure called (invertible) L-fuzzy rough hyperideals is defined and investigated. [ABSTRACT FROM AUTHOR]

Although adipose tissue is an expandable and readily attainable source of proliferating, multipotent stem cells, its potential for use in regenerative medicine has not been extensively explored. Here we report that adult human and mouse adipose-derived stem cells can be reprogrammed to induced pluripotent stem (iPS) cells with substantially higher efficiencies than those reported for human and mouse fibroblasts. Unexpectedly, both human and mouse iPS cells can be obtained in feeder-free conditions. We discovered that adipose-derived stem cells intrinsically express high levels of pluripotency factors such as basic FGF, TGFβ, fibronectin, and vitronectin and can serve as feeders for both autologous and heterologous pluripotent cells. These results demonstrate a great potential for adipose-derived cells in regenerative therapeutics and as a model for studying the molecular mechanisms of feeder-free iPS generation and maintenance. [ABSTRACT FROM AUTHOR]

Although peroxisome proliferator-activated receptor gamma (PPARy) agonists such as thiazolidinediones (TZDs) are widely used to treat type 2 diabetes, how its activation in individual tissues contributes to TZD's therapeutic action remains controversial. As TZDs are known to have receptor-independent effects, we sought to establish gain-of- function animal models to delineate the receptor's insulin-sensitizing actions. Unexpectedly, we find that selective activation of PPAR7 in adipocytes, but not in macrophages, is sufficient for whole-body insulin sensitization equivalent to systemic TZD treatment. In addition to improved adipokine, inflammatory, and lipid profiles, PPAR7 activation in mature adipocytes normalizes serum insulin without increased adipogenesis. Co-culture studies indicated that PPARy-activated adipocytes broadly suppress induction of inflammatory cytokines and C-X-C family chemokines in macrophages. Collectively, these data describe an "adipocentric" model in which adipose activation of PPAR7 is sufficient for complete insulin sensitization and suggest a specific application for fat selective PPAR7 modulators in diabetic therapy. [ABSTRACT FROM AUTHOR]

In this paper, we consider the characterization of h -semisimple hemirings. First, the notions of (∈,∈ vq) -fuzzy h -ideals and (∈,∈ vq) -fuzzy h -interior ideals of a hemiring are introduced, and some of their properties are investigated. Then the concept of h -semisimple hemirings is introduced and its characterizations are established. [ABSTRACT FROM AUTHOR]

In this paper, the concept of a fuzzy h-bi-ideal, a fuzzy h-quasi-ideal in a hemiring is introduced, and some related properties of such fuzzy h-ideals are investigated. Also, the notions of h-hemiregular hemirings and h-hemiregular fuzzy duo hemirings are given, and their characterizations in terms of h-ideals and fuzzy h-ideals are studied [ABSTRACT FROM AUTHOR]

In this paper, using the concept of fuzzy points, we study the fuzzy point power rings. The properties and structures of fuzzy point power ring are described systematically. Finally, the relations between the fuzzy point power rings and crisp power rings are discussed. [ABSTRACT FROM AUTHOR]

In this paper, the authors introduce and study the fuzzy prime ideals, completely fuzzy prime (semiprime) ideals, fuzzy primary ideals and the radical of fuzzy ideals in fuzzy semigroups based on fuzzy points. [ABSTRACT FROM AUTHOR]