Carretier, Séverine, Chen, Li-An, Venault, Antoine, Yang, Zhong-Ru, Aimar, Pierre, and Chang, Yung
Literature on the design of efficient nonfouling membranes by in-situ modification is poor, which can be explained by the difficulty to control membrane formation mechanisms when a third material is added to the casting solution, or by the lack of stability of matrix polymers with surface-modifiers. We present polyvinylidene fluoride membranes formed by vapor-induced phase separation and modified with a tri-block copolymer of poly(styrene) and poly(ethylene glycol) methacrylate moieties (PEGMA 124 - b -PS 54 - b -PEGMA 124 ). After characterizing the copolymer, we move onto membrane formation mechanisms. Membrane formation is well controlled and leads to structure close to bi-continuous. Considering the formulation chosen, PVDF/PEGMA 124 - b -PS 54 - b -PEGMA 124 solutions are less viscous and more hydrophilic than virgin PVDF solutions. Both effects promote non-solvent transfer, thus decreasing the chances for crystallization. Hydrophilic capability of membranes is increased from about 59 mg/cm 3 to 650 mg/cm 3 , leading to a severe drop of non-specific protein adsorption, up to 85–90%, also depending on its nature. Biofouling at the micro-scale by modified Escherichia coli and Streptococcus mutans is almost totally inhibited. Finally, biofouling is importantly reduced in dynamic conditions, as measured from the water flux recovery ratio of 69.4%, after 3 water-BSA filtration cycles, much higher than with a commercial hydrophilic PVDF membrane (47.3%). These membranes hold promise as novel materials for water-treatment or blood filtration. [ABSTRACT FROM AUTHOR]