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1. Design and Synthesis of Brazilin-Like Compounds.

Author

Chengxue Pan, Xianghui Zeng, Yifu Guan, Xiangliu Jiang, Liang Li, and Hongbin Zhang

Subjects
BIOACTIVE compounds, ANTINEOPLASTIC antibiotics, CANCER treatment, CELL lines, HYDROLYSIS
Abstract

A general and flexible synthetic route, which leads to the synthesis of brazilin-like compounds, was developed. The azabrazilin derivatives show strong anticancer activities in MTT assay towards a number of human cancer cell lines including HT29, A549, HL60, and K562. [ABSTRACT FROM AUTHOR]

Published
2011
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