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We presented the development of a consensus guideline for managing juvenile idiopathic arthritis-associated uveitis (JIAU) in Taiwan, considering regional differences in manifestation and epidemiology. The Taiwan Ocular Inflammation Society (TOIS) committee formulated this guideline using a modified Delphi approach with two panel meetings. Recommendations were based on a comprehensive evidence-based literature review and expert clinical experiences, and were graded according to the Oxford Centre for Evidence-Based Medicine's “Levels of Evidence” guideline (March 2009). The TOIS consensus guideline consists of 10 recommendations in four categories: screening and diagnosis, treatment, complications, and monitoring, covering a total of 27 items. These recommendations received over 75% agreement from the panelists. Early diagnosis and a coordinated referral system between ophthalmologists and pediatric rheumatologists are crucial to prevent irreversible visual impairment in children with JIAU. However, achieving a balance between disease activity and medication use remains a key challenge in JIAU management, necessitating further clinical studies.

Purpose: To propose a modified Quickert procedure combined with prolapsed fat and preseptal orbicularis muscle removal which corrects involutional lower eyelid entropion, and to validate the procedure as an adequate surgical management according to anatomical deformities and pathogenesis of Asian patients. Methods: Ninety-five patients (45 men, 50 women; 108 eyelids [55 right eyes, 53 left eyes]) who underwent this modified surgical procedure with a minimum follow-up period of 2 months were examined. All pre- and post-operative evaluations and surgical procedure were performed exclusively from the same oculoplastic surgeon. Postoperative results, recurrence rate, and complications were assessed. Results: The mean follow-up period was 13.33 months (range, 2–67 months). Of the 108 eyelids, 4 developed recurrent entropion with trichiasis, corresponding to an overall recurrence rate of 3.70%. No major complications, such as overcorrection (ectropion), symblepharon, infection, or wound dehiscence, occurred during the follow-up period after surgery. Of these 4 eyelids exhibiting recurrence, 3 occurred within 10 months and 1 occurred 49 months after surgery. Three recurrent patients received secondary surgery for re-correction with successful results. Conclusion: The modified Quickert procedure combined with prolapsed fat and preseptal orbicularis muscle removal not only demonstrated safety and effectiveness, but also led to low rate of recurrence and complications. It could be a strategy for correction of involutional entropion in Asian patients.

Abstract Background Vibrio cholerae non-O1 is a virulent pathogen that causes significant morbidity and mortality in humans. Herein, we report a case of corneal ulcer caused by this pathogen. Case presentation A 59-year-old fisherman with no systemic history was struck in the right eye by a marine shrimp and developed keratitis. Corneal scrapping culture revealed the presence of the V. cholerae non-O1, and its identification was confirmed by Analytical Profile Index 20E system and polymerase chain reaction. He was successfully treated with topical levofloxacin (0.3%) and fortified amikacin (12.5 mg/mL) for 2 weeks. The visual acuity recovered to 20/25 after treatment without complications. Conclusions This is the first case report of keratitis caused by V. cholerae non-O1 strain. Ocular injury by marine creatures and contaminated seawater can contribute to severe corneal ulcer. Early diagnosis can be achieved by meticulous history taking and a comprehensive laboratory workup. Simultaneously, an effective antibiotic therapy can lead to a positive outcome.

A new external algorithm with sensing circuit are proposed to compensate AMOLED display degradation. The compensation is enabled by first evaluating degradation level of OLEDs based on the OLED anode voltages detected by a newly-designed sensing subcircuit. According to sensed voltages, the external algorithm selects appropriate built-in models to compensate OLED degradation with the aim to achieve expected OLED emitted luminance. The models are established based on prior measurements to prescribe the relations between luminance and current (L-I) and luminance and voltage (L-V) of each OLED. In this way of compensation, the proposed method is able to incorporate negative effects of OLED degradation aggravation while increasing driving current to compensate the original decay in OLED luminance. Moreover, another algorithm along with the 4T0.5C pixel circuit as presented in prior studies are adopted to compensate process variation in Vth among pixels for improving the emission uniformity of an AMOLED panel. Experiments are conducted by combining the external algorithm with sensing circuit and the pixel circuit to validate the performances of compensating and alleviating OLED degradation. [ABSTRACT FROM PUBLISHER]

This study presents design, analysis and experiment of a miniaturized rotary generator in size of 10 × 10 × 2 mm3 and its compact energy harvest circuit chip. The designed generator consists of patterned planar copper coils and a multipolar hard magnet ring made of NdFeB. To perform modeling, a harmonic-like magnetic field model along the circumferential path of each magnetic pole is assumed with the assistance from measured peak magnetic flux densities. This is followed by the application of Faraday's law to predict generated electromotive forces (EMF5) in terms of the relative rotational speed between the magnet ring and coils. The genetic algorithm (GA) is next applied to optimize the critical dimensions of the miniaturized generator. The theoretical model of this power microgenerator is evaluated and compared with experimental results, and it is found that the analytical simulation shows a good agreement with the experimental results. The optimized generator offers 4.5 V and 7.23 mW in root mean square (rms) at 10000 r/min. With microgenerator successfully fabricated, a novel energy harvest circuit employing Dickson charge pump is designed and fabricated via the 0.35-u. process offered by National Chip Implementation Center (CIC) of Taiwan. This charge pump circuit owns the merit of almost-zero thresholds of employed metal-oxide-semiconductor (MOS) transistors, enabling the conversion of low-power alternating current (ac) signals by the microgenerator to direct current (dc) ones. [ABSTRACT FROM AUTHOR]