7 results on '"Vito Liotino"'
Search Results
2. Bilateral pulmonary nodules and acute respiratory failure in a 22-year-old man with dyspnoea and fever
- Author
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Giorgio Castellana, Vito Liotino, Maria Rosaria Vulpi, Ina Ali, Lorenzo Marra, and Onofrio Resta
- Subjects
Diseases of the respiratory system ,RC705-779 - Published
- 2017
- Full Text
- View/download PDF
3. Reduction of Sniff Nasal Inspiratory Pressure (SNIP) as an Early Indicator of the Need of Enteral Nutrition in Patients with Amyotrophic Lateral Sclerosis
- Author
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Stefano Zoccolella, Rosa Capozzo, Vitaliano N. Quaranta, Giorgio Castellana, Lorenzo Marra, Vito Liotino, Vincenza Giorgio, Isabella L. Simone, Onofrio Resta, Marco Piccininni, Rosanna Tortelli, and Giancarlo Logroscino
- Subjects
amyotrophic lateral sclerosis ,percutaneous endoscopic gastrostomy ,sniff nasal inspiratory pressure ,prognosis ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Percutaneous endoscopic gastrostomy (PEG) is the standard procedure for feeding severely dysphagic patients with amyotrophic lateral sclerosis (ALS). It is associated with prolonged survival and improvement in quality of life. Nasal inspiratory pressure during a sniff (SNIP) is a respiratory test used extensively in ALS for the assessment of inspiratory muscle strength. In this study, we aimed to investigate the role of SNIP at baseline to predict PEG placement in ALS. Data from a clinical incident cohort of 179 ALS cases attending the multidisciplinary ALS unit of the University of Bari between April 2006 and December 2012 were retrospectively analysed. At baseline, patients underwent detailed neurological, nutritional and respiratory assessments, including measurements of SNIP and forced vital capacity (FVC). Patients were therefore followed up approximately every three to six months until they were able to attend the centre. The censoring date for the survival analysis was 15 April 2014, with PEG placement as the main outcome. Cox proportional hazard regression models were used to examine the association between SNIP and PEG placement, adjusted for possible confounders. During the follow-up period, 75 participants (42%) received PEG implant. PEG placement was more frequent (57% vs. 31%; p = 0.001) and earlier (after 11.6 ± 14.0 months from the first visit, vs. 23.3 ± 15.5 months; p < 0.0001) in the group of patients with baseline SNIP ≤ 40 cm H2O. Baseline SNIP was a predictor of PEG placement even after correction for multiple potential confounders (HR 0.98; 95% CI: 0.96–0.99; p = 0.02). To conclude, the present study showed that SNIP at baseline is an early indicator of disease progression and therefore of the need for enteral nutrition in ALS.
- Published
- 2021
- Full Text
- View/download PDF
4. Metabolic syndrome and Chronic Obstructive Pulmonary Disease (COPD): The interplay among smoking, insulin resistance and vitamin D.
- Author
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Giuseppina Piazzolla, Anna Castrovilli, Vito Liotino, Maria Rosaria Vulpi, Margherita Fanelli, Antonio Mazzocca, Mafalda Candigliota, Elsa Berardi, Onofrio Resta, Carlo Sabbà, and Cosimo Tortorella
- Subjects
Medicine ,Science - Abstract
A close relationship between Metabolic Syndrome (MetS) and Chronic Obstructive Pulmonary Disease (COPD) has been described, but the exact nature of this link remains unclear. Current epidemiological data refer exclusively to the MetS prevalence among patients with COPD and data about the prevalence of COPD in MetS patients are still unavailable.To analyse and compare risk factors, clinical and metabolic characteristics, as well as the main respiratory function parameters, among patients affected by MetS, COPD or both diseases.We recruited 59 outpatients with MetS and 76 outpatients with COPD. After medical history collection, physical examination, blood sampling for routine analysis, spirometric evaluation, they were subdivided into MetS (n = 46), MetS+COPD (n = 60), COPD (n = 29).A MetS diagnosis was assigned to 62% of COPD patients recruited in the COPD Outpatients Clinic of the Pneumology Department, while the COPD prevalence in MetS patients enrolled in the Internal Medicine Metabolic Disorders Outpatients Clinic was 22%. More than 60% of subjects enrolled in each Department were unaware that they suffered from an additional disease. MetS+COPD patients exhibited significantly higher C-peptide levels. We also found a positive relation between C-peptide and pack-years in all subjects and a negative correlation between C-peptide and vitamin D only in current smokers. Finally, a negative association emerged between smoking and vitamin D.We have estimated, for the first time, the COPD prevalence in MetS and suggest a potential role of smoking in inducing insulin resistance. Moreover, a direct effect of smoking on vitamin D levels is proposed as a novel mechanism, which may account for both insulin resistance and COPD development.
- Published
- 2017
- Full Text
- View/download PDF
5. Reduction of Sniff Nasal Inspiratory Pressure (SNIP) as an Early Indicator of the Need of Enteral Nutrition in Patients with Amyotrophic Lateral Sclerosis
- Author
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Onofrio Resta, Giorgio Castellana, Vito Liotino, Vitaliano Nicola Quaranta, Isabella Laura Simone, Marco Piccininni, Vincenza Giorgio, Stefano Zoccolella, Lorenzo Marra, Rosanna Tortelli, Rosa Capozzo, and Giancarlo Logroscino
- Subjects
Vital capacity ,amyotrophic lateral sclerosis ,business.industry ,General Neuroscience ,medicine.medical_treatment ,Neurosciences. Biological psychiatry. Neuropsychiatry ,medicine.disease ,percutaneous endoscopic gastrostomy ,Article ,FEV1/FVC ratio ,Parenteral nutrition ,Quality of life ,Anesthesia ,Percutaneous endoscopic gastrostomy ,Cohort ,medicine ,sniff nasal inspiratory pressure ,prognosis ,Amyotrophic lateral sclerosis ,business ,Survival analysis ,RC321-571 - Abstract
Percutaneous endoscopic gastrostomy (PEG) is the standard procedure for feeding severely dysphagic patients with amyotrophic lateral sclerosis (ALS). It is associated with prolonged survival and improvement in quality of life. Nasal inspiratory pressure during a sniff (SNIP) is a respiratory test used extensively in ALS for the assessment of inspiratory muscle strength. In this study, we aimed to investigate the role of SNIP at baseline to predict PEG placement in ALS. Data from a clinical incident cohort of 179 ALS cases attending the multidisciplinary ALS unit of the University of Bari between April 2006 and December 2012 were retrospectively analysed. At baseline, patients underwent detailed neurological, nutritional and respiratory assessments, including measurements of SNIP and forced vital capacity (FVC). Patients were therefore followed up approximately every three to six months until they were able to attend the centre. The censoring date for the survival analysis was 15 April 2014, with PEG placement as the main outcome. Cox proportional hazard regression models were used to examine the association between SNIP and PEG placement, adjusted for possible confounders. During the follow-up period, 75 participants (42%) received PEG implant. PEG placement was more frequent (57% vs. 31%, p = 0.001) and earlier (after 11.6 ± 14.0 months from the first visit, vs. 23.3 ± 15.5 months, p <, 0.0001) in the group of patients with baseline SNIP ≤ 40 cm H2O. Baseline SNIP was a predictor of PEG placement even after correction for multiple potential confounders (HR 0.98, 95% CI: 0.96–0.99, p = 0.02). To conclude, the present study showed that SNIP at baseline is an early indicator of disease progression and therefore of the need for enteral nutrition in ALS.
- Published
- 2021
6. Bilateral pulmonary nodules and acute respiratory failure in a 22-year-old man with dyspnoea and fever
- Author
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Ina Ali, Giorgio Castellana, Vito Liotino, Maria Rosaria Vulpi, Lorenzo Marra, and Onofrio Resta
- Subjects
Pulmonary and Respiratory Medicine ,lcsh:RC705-779 ,Pediatrics ,medicine.medical_specialty ,business.industry ,fungi ,food and beverages ,Case Report ,lcsh:Diseases of the respiratory system ,Expert Opinion ,030218 nuclear medicine & medical imaging ,respiratory tract diseases ,03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,medicine ,Acute respiratory failure ,business - Abstract
A 22-year-old white male presented complaining of a 3-week history of fatigue, cough and haemoptysis, accompanied by fever (38°C max), dyspnoea and mucopurulent sputum in the last few days. He denied nausea, vomiting, diarrhoea, dysuria and weight loss., Can you diagnose the cause of this man’s bilateral pulmonary nodules and acute respiratory failure? http://ow.ly/NfED30dDBzm
- Published
- 2017
7. Adherence to GOLD guidelines in real-life COPD management in the Puglia region of Italy
- Author
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Vincenzo Mastrosimone, Pier Luigi Di Napoli, Piertro Schino, Vito Liotino, Donato Lacedonia, E. Attolini, Giuseppe Antonio Palmiotti, Mauro Carone, Maria Pia Foschino Barbaro, Elio Costantino, Francesco Satriano, Emanuela Resta, Eugenio Sabato, and Alfredo Scoditti
- Subjects
Adult ,Male ,medicine.medical_specialty ,web platform ,Exacerbation ,Population ,International Journal of Chronic Obstructive Pulmonary Disease ,appropriateness ,Severity of Illness Index ,03 medical and health sciences ,Pulmonary Disease, Chronic Obstructive ,0302 clinical medicine ,Pharmacotherapy ,Internal medicine ,Forced Expiratory Volume ,Health care ,Medicine ,Outpatient clinic ,Humans ,COPD ,030212 general & internal medicine ,Practice Patterns, Physicians' ,education ,Aged ,Original Research ,education.field_of_study ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Obstructive lung disease ,Bronchodilator Agents ,Pulmonology ,Cross-Sectional Studies ,Treatment Outcome ,health care spending ,030228 respiratory system ,Italy ,Female ,online survey ,Guideline Adherence ,business - Abstract
Giuseppe Antonio Palmiotti,1 Donato Lacedonia,1 Vito Liotino,2 Pietro Schino,3 Francesco Satriano,4 Pier Luigi Di Napoli,3 Eugenio Sabato,5 Vincenzo Mastrosimone,6 Alfredo Scoditti,7 Mauro Carone,8 Elio Costantino,9 Emanuela Resta,2 Ettore Attolini,10 Maria Pia Foschino Barbaro1 1Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, University of Foggia, Foggia, Italy; 2Department of Cardiac, Thoracic, and Vascular Science, Institute of Respiratory Diseases, School of Medicine, University of Bari, Bari, Italy; 3Physiopathology Respiratory Unit, F Miulli General Hospital, Acquaviva delle Fonti, Bari, Italy; 4Pneumology Clinic, Vito Fazzi Hospital, Lecce, Italy; 5UOC of Pneumology, “N Melli” Hospital, San Pietro Vernotico, Italy; 6Division of Pulmonary Disease, Medical Center of Rehabilitation, Foundation Salvatore Maugeri, IRCCS, Marina di Ginosa, Italy; 7Department of Respiratory Diseases, San Camillo Clinic, Taranto, Italy; 8Division of Pulmonary Disease, Medical Center of Rehabilitation, Foundation Salvatore Maugeri, IRCCS, Cassano delle Murge, Italy; 9UOC of Pneumology, Hospital “Madonna delle Grazie”, Matera, Italy; 10Regional Health Agency (ARES), Bari, Italy Background: COPD is a disease associated with significant economic burden. It was reported that Global initiative for chronic Obstructive Lung Disease (GOLD) guideline-oriented pharmacotherapy improves airflow limitation and reduces health care costs. However, several studies showed a significant dissociation between international recommendations and clinicians’ practices. The consequent reduced diagnostic and therapeutic inappropriateness has proved to be associated with an increase in costs and a waste of economic resources in the health sector. The aim of the study was to evaluate COPD management in the Puglia region. The study was performed in collaboration with the pulmonology centers and the Regional Health Agency (AReS Puglia). Methods: An IT platform allowed the pulmonologists to enter data via the Internet. All COPD patients who visited a pneumological outpatient clinic for the first time or for regular follow-ups or were admitted to a pneumological department for an exacerbation were considered eligible for the study. COPD’s diagnosis was confirmed by a pulmonologist at the moment of the visit. The project lasted 18months and involved 17 centers located in the Puglia region. Results: Six hundred ninety-three patients were enrolled, evenly distributed throughout the region. The mean age was 71±9years, and 85% of them were males. Approximately 23% were current smokers, 63% former smokers and 13.5% never smokers. The mean post-bronchodilator forced expiratory volume in 1second was 59%±20% predicted. The platform allowed the classification of patients according to the GOLD guidelines (Group A: 20.6%, Group B: 32.3%, Group C: 5.9% and Group D: 39.2%), assessed the presence and severity of exacerbations (20% of the patients had an exacerbation defined as mild [13%], moderate [37%] and severe [49%]) and evaluated the appropriateness of inhalation therapy at the time of the visit. Forty-nine percent of Group A patients were following inappropriate therapy; in Group B, 45.8% were following a therapy in contrast with the guidelines. Among Group C patients, 41.46% resulted in triple combination therapy, while ~14% of Group D patients did not have a therapy or were following an inappropriate therapy. In conclusion, 30% of all patients evaluated had been following an inadequate therapy. Subsequently, an online survey was developed to inquire about the reasons for the results obtained. In particular, we investigated the reasons why 30% of our population did not follow the therapy suggested by the GOLD guidelines: 1) why was there an excessive use of inhaled corticosteroids, 2) why a significantly high percentage was inappropriately treated with triple therapy and 3) why a consistent percentage (11%) of Group D patients were not treated at all. Conclusion: The data provides an overview on the management of COPD in the region of Puglia (Italy) and represents a resource in order to improve appropriateness and reduce the waste of health resources. Keywords: COPD, appropriateness, web platform, health care spending, online survey
- Published
- 2018
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