200 results on '"Vijayan, V K"'
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2. Diagnosis of Novel Pandemic Influenza Virus 2009 H1N1 in Hospitalized Patients
- Author
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Kumar, P., Kumar, B., Gupta, A., Sharma, B., Vijayan, V. K., Khare, S., Singh, V., Daga, M. K., Chadha, M. S., Mishra, A. C., Kaur, H., and Khanna, M.
- Published
- 2010
- Full Text
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3. Pandemic swine influenza virus (H1N1): A threatening evolution
- Author
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Khanna, Madhu, Kumar, Binod, Gupta, Neha, Kumar, Prashant, Gupta, Ankit, Vijayan, V. K., and Kaur, Harpreet
- Published
- 2009
- Full Text
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4. Influenza A (H1N1) 2009: a pandemic alarm
- Author
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Khanna, Madhu, Gupta, Neha, Gupta, Ankit, and Vijayan, V. K.
- Published
- 2009
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5. Emerging influenza virus: A global threat
- Author
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Khanna, M., Kumar, P., Choudhary, K., Kumar, B., and Vijayan, V. K.
- Published
- 2008
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6. Poster abstracts
- Author
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Ferrie, J., Shipley, M., Cappuccio, F., Brunner, E., Miller, M., Kumari, M., Marmot, M., Coenen, A., Castillo, J. L., Araya, F., Bustamante, G., Montecino, L., Torres, C., Oporto, S., Gronli, J., Fiske, E., Murison, R., Bjorvatn, B., Sorensen, E., Ursin, R., Portas, C. M., Rajaraman, S., Gribok, A., Wesensten, N., Balkin, T., Reifman, J., Dursunoglu, N., Ozkurt, S., Baser, S., Delen, O., Sarikaya, S., Sadler, P., Mitchell, P., Françon, D., Decobert, M., Herve, B., Richard, A., Griebel, G., Avenet, P., Scatton, B., Fur, G. L., Eckert, D., Jordan, A., Wellman, A., Smith, S., Malhotra, A., White, D., Bruck, D., Thomas, I., Kritikos, A., Oertel, W., Stiasny-Kolster, K., Garcia-Borreguero, D., Poewe, W., Hoegl, B., Kohnen, R., Schollmayer, E., Keffel, J., Trenkwalder, C., Valle, A., Roizenblatt, S., Fregni, F., Boggio, P., Tufik, S., Ward, K., Robertson, L., Palmer, L., Eastwood, P., Hillman, D., Lee, J., Mukherjee, S., de Padova, V., Barbato, G., Ficca, G., Zilli, I., Salzarulo, P., Veldi, M., Hion, T., Vasar, V., Kull, M., Nowak, L., Davis, J., Latzer, Y., Tzischinsky, O., Crowley, S., Carskadon, M., Anca-Herschkovitsch, M., Frey, D., Ortega, J., Wiseman, C., Farley, C., Wright, K., Campbell, A., Neill, A., Spiegel, K., Leproult, R., Tasali, E., Scherberg, N., van Cauter, E., Noradina, A. T., Karim, N. A., Norlinah, I., Raymond, A. A., Sahathevan, R., Hamidon, B., Werth, E., Poryazova, R., Khatami, R., Bassetti, C., Beran, R. G., Ainley, L., Holand, G., Duncan, J., Kinney, H., Davis, B., Hood, B., Frey, S., Schmidt, C., Hofstetter, M., Peigneux, P., Cajochen, C., Hu, W.-P., Li, J.-D., Zhang, C., Boehmer, L., Siegel, J., Zhou, Q.-Y., Sagawa, Y., Kondo, H., Takemura, T., Kanayama, H., Kaneko, Y., Sato, M., Kanbayashi, T., Hishikawa, Y., Shimizu, T., Viola, A., James, L., Schlangen, L., Dijk, D.-J., Andretic, R., Kim, Y.-C., Han, K.-A., Jones, F., Greenspan, R., Sanford, L., Yang, L., Tang, X., Dieter, K., Uta, E., Sven, H., Richard, M., Oyane, N., Pallesen, S., Holsten, F., Inoue, Y., Fujita, M., Emura, N., Kuroda, K., Uchimura, N., Johnston, A., Astbury, J., Kennedy, G., Hoedlmoser, K., Schabus, M., Pecherstorfer, T., Moser, S., Gruber, G., Anderer, P., Klimesch, W., Naidoo, N., Ferber, M., Pack, A., Neu, D., Mairesse, O., Hoffmann, G., Dris, A., Lambrecht, L., Linkowski, P., Verbanck, P., Le Bon, O., Matsuura, N., Yamao, M., Adachi, N., Aritomi, R., Komada, Y., Tanaka, H., Shirakawa, S., Kondoh, H., Takemura, F., Ohnuma, S., Suzuki, M., Uemura, S., Iskra-Golec, I., Smith, L., Thanh, D.-V., Boly, M., Phillips, C., Steven, L., Luxen, A., Maquet, M., Jay, S., Dawson, D., Lamond, N., Basner, M., Fomberstein, K., Dinges, D., Ogawa, K., Nittono, H., Yamazaki, K., Hori, T., Glamann, C., Hornung, O., Hansen, M.-L, Danker-Hopfe, H., Jung, C., Kecklund, G., Anund, A., Peters, B., Åkerstedt, T., Verster, J., Roehrs, T., Mets, M., de Senerpont Domis, L., Olivier, B., Volkerts, E., Knutson, K., Lauderdale, D., Rathouz, P., Christie, M., Chen, L., Bolortuya, Y., Lee, E., Mckenna, J., Mccarley, R., Strecker, R., Tamaki, M., Matsuoka, T., Aritake, S., Suzuki, H., Kuriyama, K., Ozaki, A., Abe, Y., Enomoto, M., Tagaya, H., Mishima, K., Matsuura, M., Uchiyama, M., Lima-Pacheco, E., Davis, K., Sabourin, C., Lortie-Lussier, M., de Koninck, J., van Der Werf, Y., van Der Helm, E., Schoonheim, M., van Someren, E., Tokley, M., Ball, M., Sato, T., Ghilardi, M. F., Moisello, C., Bove, M., Busi, M., Pelosin, E., Tononi, G., Eguchi, N., Sakata, M., Urade, Y., Doe, N., Yoshihara, K., Abe, K., Manabe, Y., Iwatsuki, K., Hayashi, T., Shoji, M., Kamiya, T., Gooley, J., Brainard, G., Rajaratnam, S., Kronauer, R., Czeisler, C., Lockley, S., Phillips, A., Robinson, P., Burgess, H., Revell, V., Eastman, C., Bihari, S., Ramakrishnan, N., Camerino, D., Conway, P. M., Costa, G., Vandewalle, G., Albouy, G., Sterpenich, V., Darsaud, A., Rauchs, G., Berken, P.-Y, Balteau, E., Maquet, P., Tendero, J. A., Domenech, M. P., Isern, F. S., Martínez, C., Roure, N., Sancho, E. E., Moreno, C. R., Silva, M., Marqueze, E. C., Waage, S., Bobko, N., Chernyuk, V., Yavorskiy, Y., Saxvig, I., Sørensen, E., de Mello, M. T., Esteves, A., Teixeira, C., Bittencourt, L. R., Silva, R., Pires, M. L., Mottram, V., Middelton, B., Arendt, J., Amaral, O., Rodrigues, M., Pereira, C., Tavares, I., Baba, K., Honma, S., Honma, K.-I., Yamanaka, Y., Hashimoto, S., Tanahashi, Y., Nishide, S.-Y, Honma, K.-I, Sletten, T., Middleton, B., Lederle, K., Skene, D., Roth, T., Walsh, J., Hogben, A., Ellis, J., Archer, S., von Schantz, M., Chen, N.-H., Wang, P.-C., Chen, C.-W., Lin, Y., Shih, T.-S., Armstrong, S., Redman, J., Stephan, E., David, M., Delanaud, S., Chardon, K., Libert, J.-P., Bach, V., Telliez, F., Reid, K., Jaksa, A., Eisengart, J., Kane, P., Naylor, E., Zee, P., Viola, A. U., de Valck, E., Hofmans, J., Theuns, P., Cluydts, R., Alexander, G., Karel, M., Christina, R., Sohn, I.-K., Cho, I. H., Kim, S. J., Yu, S.-H., Kim, H., Yoo, S. Y., Koh, S.-H., Cho, S.-J., Rotenberg, L., Silva-Costa, A., Griep, R. H., Amely, T., Kennedy, G. A., Pavlis, A., Thompson, B., Pierce, R., Howard, M., Briellmann, R., Venkateswaran, S., Blunden, S., Krawczyk, E., Blake, J., Gururajan, R., Kerr, D., Matuisi, T., Iwasaki, M., Yamasita, N., Iemura, A., Ohya, T., Yanagawa, T., Misa, R., Coleman, G., Conduit, R., Duce, B., Hukins, C., Nyandaiti, Y. W., Bamaki, S., Mohammed, A., Kwajarfa, S., Veeramachaneni, S. P., Murthy, A., Wilson, A., Maul, J., Hall, G., Stick, S., Moseley, L., Gradisar, M., Kurihara, T., Yamamoto, M., Yamamoto, S., Kuranari, M., Sparks, C. B., Bartle, A., Beckert, L., Latham-Smith, F. B., Hilton, J., Whitehead, B., Gulliver, T., Salvini, A., Grahame, S., Swift, M., Laybutt, N., Sharon, D., Mack, C., Hymell, B., Perrine, B., Ideshita, K., Taira, M., Matuo, A., Furutani, M., van Dongen, H., Mott, C., Huang, J.-K., Mollicone, D. J., Mckenzie, F., Dinges, David, Barnes, M., Rochford, P., Churchward, T., O’Donoghue, F., Penzel, T., Fietze, I., Canisius, S., Bekiaris, E., Terrill, P. I., Wilson, S., Suresh, S., Cooper, D., Suzuki, T., Ouchi, K., Moriya, A., Kameyama, K., Takahashi, M., Büttner, A., Rühle, K.-H., Wang, D., Wong, K., Dungan, II, G., Grunstein, R., Davidson, P., Jones, R., Gergely, V., Mashima, K., Miyazaki, S., Tanaka, T., Okawa, M., Yamada, N., Wyner, A., Raizen, D., Galante, R., Ng, A. K., Koh, T. S., Lim, L. L., Puvanendran, K., Peiris, M., Bones, P., Roebuck, T., Ho, S., Szollosi, I., Naughton, M., Williams, G., Parsley, C., Harris, M.-A., Thornton, A., Ruehland, W., Banks, S., Arroyo, S., Carroll, K., Pilmore, J., Stewart, C., Hamilton, G., van Acker, F., Cvetkovic, D., Holland, G., Cosic, I., Tolson, J., Worsnop, C., Cresswell, P., Hart, I., Bouarab, M., Delechelle, E., Drouot, X., Acebo, C., Singh, P., Lakey, T., Schachter, L., Rand, J., Collin, H., Snyder, E., Ma, J., Svetnick, V., Deacon, S., Dana, B., Konstanze, D., Uwe, M., Ingo, F., Thomas, P., Ivar, R., Mackiewicz, M., Shockley, K., Romer, M., Zimmerman, J., Baldwin, D., Jensen, S., Churchill, G., Paigen, B., Imeri, L., Ferrari, L., Bianchi, S., Dossena, S., Garofoli, A., Mangieri, M., Tagliavini, F., Forloni, G., Chiesa, R., Pedrazzoli, M., Pereira, D., Veauny, M., Bodenmann, S., Hohoff, C., Freitag, C., Deckert, J., Rétey, J., Landolt, H.-P., Strohl, K., Price, E., Yamauchi, M., Dostal, J., Feng, P., Han, F., Havekes, R., Novati, A., Hagewoud, R., Barf, P., van Der Borght, K., van Der Zee, E., Meerlo, P., Ruby, P., Caclin, A., Boulet, S., Delpuech, C., Morlet, D., Veasey, S., Aton, S., Jha, S., Coleman, T., Seibt, J., Frank, M., Lack, L., Churches, O., Feng, S. Y. S., Cassaglia, P., Yu, V. Y. H., Walker, A. M., Kohler, M., Kennedy, D., Martin, J., van Den Heuvel, C., Lushington, K., Herron, K., Khurana, C., Sterr, A., Olivadoti, M., Toth, L., Opp, M., Dang-Vu, T., Degueldre, C., Gais, S., Dang-Vu, T. T., Desseilles, M., Philips, C., Chijavadze, E., Babilodze, M., Chkhartishvili, E., Nachkebia, N., Mchedlidze, O., Dzadzamia, S., Griffiths, R., Walker, A., Horovitz, S., Fukunaga, M., Carr, W., Picchioni, D., de Zwart, J., van Gelderen, P., Braun, A., Duyn, J., Hanlon, E. H., Faraguna, U., Vyazovskiy, V., Cirelli, C., Ocampo-Garcés, A., Ibáñez, F., López, S., Vivaldi, E., Torrealba, F., Romanowski, C. P. N., Fenzl, T., Flachskamm, C., Deussing, J., Kimura, M., Tarokh, L., van Reen, E., Dorn, H., Velluti, R., Qu, W.-M., Huang, Z.-L., Hayaishi, O., Pedemonte, M., Drexler, D., Pol-Fernández, D., Bernhardt, V., Lopez, C., Rodriguez-Servetti, Z., Romanowski, C., Polta, S., Yassouridis, A., Abe, T., Takahashi, K., Koyama, Y., Kayama, Y., Lin, J.-S., Sakai, K., Gulia, K., Karashima, A., Shimazaki, M., Katayama, N., Nakao, M., Winsky-Sommerer, R., Knapman, A., Tobler, I., Altena, E., Sanz-Arigita, E., Chang, F.-C., Lu, C.-Y., Yi, P.-L., Hsiao, Y.-Z., Lowden, A., Nilsson, J., Hillert, L., Wiholm, C., Kuster, N., Arnetz, B., Szameitat, A., Shen, S., Daurat, A., Tiberge, M., Sok, N., D’Ortho, M. P. I. A., Karasinsky, P., Kohlmeier, K., Wess, J., Leonard, C., Kristensen, M., Kalinchuk, A., Porkka-Heiskanen, T., Mccarley, R. W., Basheer, R., Aizawa, R., Sunahara, H., Abe, S.-I., Iwaki, S., Houjyou, M., Satoh, M., Suda, H., Kheirandish-Gozal, L., Gozal, D., Walker, P., Noa, A., O’Driscoll, D., Ng, M., Yang, J., Davey, M., Anderson, V., Trinder, J., Horne, R., Sands, S., Kelly, V., Sia, K., Edwards, B., Skuza, E., Davidson, M., Berger, P. H. I. L. I. P., Wilkinson, M., Sánchez-Narváez, F., Gutiérrez, R., Camacho, L., Anaya, E., García-Campos, E., Labra, A., Domínguez, G., García-Polo, L., Haro, R., Verginis, N., Nixon, G., Baumert, M., Pamula, Y., Mihai, R., Wawurszak, M., Smith, N., Yiallourou, S., Andrew Ramsden, C., Williamson, B., Blecher, G., Teng, A., Dakin, C. Y. N., Yuil, M., Harris, M., Sadasivam, S., Bennison, J., Galland, B., Dawes, P., Taylor, B., Norman, M., Edwards, N., Harrison, H., Kol, C., Sullivan, C., Valladares, E., Macey, P., Kumar, R., Woo, M., Harper, R., Alger, J., Mcnamara, D., Tang, J., Goh, A., Teoh, O. H., Chiang, W. C., Chay, O. M., Marie Salvini, A., Riben, C., Blanck, A.-S., Marklund, M., Tourneux, P., Cardot, V., Leke, A., Iqbal, S. M., (Gus) Cooper, D., Witmans, M., Rodger, K., Thevasagayam, R., El-Hakim, H., Hill, C. M., Baya, A., Bucks, R., Kirkham, F., Virues-Ortega, J., Baldeweg, T., Paul, A., Hogan, A., Goodwin, J., Silva, G., Kaemingk, K., Sherrill, D., Morgan, W., Fregosi, R., Quan, S., Evans, C., Maclean, J., Waters, K., Fitzsimmons, D., Hayward, P., Fitzgerald, D., Terrill, G., O’Connell, A., Vannan, K., Richardson, H., Poluektov, M., Levin, I., Snegodskaya, M., Kolosova, N., Geppe, N., Nixon, G. Michelle, Thompson, J., Yhan, D., Becroft, D., Clark, P., Robinson, E., Waldie, K., Wild, C., Black, P., Stone, K., Britton, W., Chaves, Claudia, Tinoco, C., Goncalves, C., Ferreira, E., Santos, H., Boloto, J., Duarte, L., Paine, S., Wright, H., Slater, A., Rosen, G., Telliez, Frédéric, Djeddi, D., Kongolo, G., Degrugilliers, L., Horton, J., Buscemi, N., Vandermeer, B., Owens, J., Klassen, T., Gordon, J., King, N., Tripp, G., Oka, Y., Suzuki, S., de Lemos, M. C., Gonzaga, F. G., Shah, M. L., Bittencourt, L., Oliveira, L. V. Franco, Elshoff, J.-P., Braun, M., Andreas, J.-O., Strauss, B., Horstmann, R., Ahrweiler, S., Goldammer, N., Wada, M., Matsumoto, N., Rahman, M. D., Xu, X.-H., Makino, Y., Hashimoto, K., Zhang, M., Sastre, J.-P., Buda, C., Anaclet, C., Ohtsu, H., Danober, L., Desos, P., Cordi, A., Roger, A., Jacquet, A., Rogez, N., Thomas, J.-Y., Krentner, M., Boutin, J., Audinot-Bouchez, V., Baumann, C., Valko, P., Uhl, M., Hersberger, M., Rupp, T., Uchiyama, N., Nakamura, N., Konishi, T., Mcgrath, P., Fujiki, N., Tokunaga, J., Iijima, S., Nishino, S., Catherine, B.-R., Lely, F., Ralf, K., Oliver, N., François, J., Francois, J., Cedric, F., Changbin, Q., Patrick, H., Homanics, G., Heussler, H., Norris, R., Pache, D., Charles, B., Mcguire, T., Shelton, J., Bonaventure, P., Kelly, L., Aluisio, L., Lovenberg, T., Atack, J., Dugovic, C., Shapiro, C., Shen, J., Trajanovic, N., Chien, J., Verma, M., Fish, V., Wheatley, J., Amis, T., Alexiou, T., Wild, J., Bjursell, A., Solin, P., Sato, S., Matsubuchi, N., Gingras, M.-A., Labrosse, M., Chevrier, É, Lageix, P., Guay, M.-C., Braun, C., Godbout, R., Fatim, E. H., Loic, D., Stephane, D., Nathalie, L., Stéphane, D., Alain, G., Wiâm, R., Koabyashi, T., Tomita, S., Ishikawa, T., Manadai, O., Arakawa, K., Siato, Y., Bassi, A., Ocampo, A., Estrada, J., Blyton, D., O’Keeffe, K., Galletly, D., Larsen, P., Amatoury, J., Bilston, L., Kairaitis, K., Stephenson, R., Chu, K., Sekiguchi, Y., Suzuki, N., Yasuda, Y., Kodama, T., Honda, Y., Hsieh, K.-C., Lai, Y.-Y., Bannai, M., Kawai, N., Amici, R., Baracchi, F., Cerri, M., Del Sindaco, E., Dentico, D., Jones, C. A., Luppi, M., Martelli, D., Perez, E., Tazaki, M., Katayose, Y., Yasuda, K., Tokuyama, K., Maddison, K., Platt, P., Kirkness, J., Ware, J. C., May, J., Rosenthal, T., Park, G., Guibert, M., Allen, R. W., Cetin, T., Roman, V., Mollicone, D., Crummy, F., Cameron, P., Swann, P., Kossman, T., Taggart, F., Kandala, N.-B., Currie, A., Peile, E., Stranges, S., Marshall, N., Peltonen, M., Stenlof, K., Hedner, J., Sjostrom, L., Anderson, C., Platten, C., Jordan, K., Horne, J., Bjorkum, A., Kluge, B., Braseth, T., Gurvin, I., Kristensen, T., Nybo, R., Rosendahl, K., Nygaard, I., Biggs, S., Dollman, J., Kennedy, J. D., Martin, A. J., Haghighi, K. S., Bakht, N., Hyde, M., Harris, E., Zerouali, Y., Hosein, A., Jemel, B., Dodd, M., Rogers, N., Andersen, M., Martins, R., Alvarenga, T., Antunes, I., Papale, L., Killgore, W. S., Axelsson, J., Lekander, M., Ingre, M., Brismar, K., Dorrian, J., Ferguson, S., Jones, C., Buxton, O., Marcelli, E., Phipps-Nelson, J. O., Teixeira, L. R., de Castro Moreno, C., Turte, S. L., Nagai, R., do Rosário Dias De Oliveira Latorre, M., Marina, F., Paterson, J., Jackson, M., Johnston, P., Papafotiou, K., Croft, R., Dawson, S., Leenaars, C., Sandberg, H., Joosten, R., Dematteis, M., Feenstra, M., Wehrle, R., Rieger, M., Widmann, A., Dietl, T., Philipp, S., Wetter, T., Drummond, S., Czisch, M., Cairns, A., Lebourgeois, M., Harsh, J., Baulk, S., Vakulin, A., Catcheside, P., Antic, N., Mcevoy, D., Orff, H., Salamat, J., Meloy, M. J., Caron, A., Kostela, J., Purnell, M., Feyer, A.-M., Herbison, P., Saaresranta, T., Aittokallio, J., Karppinen, N., Toikka, J., Polo, O., Sallinen, M., Haavisto, M.-L., Hublin, C., Kiti, M., Jussi, V., Mikko, H., Chuah, L., Chee, M., Borges, F., Fischer, F., Moreno, C., Soares, N., Fonseca, M., Smolensky, M., Sackett-Lundeen, L., Haus, E., Nagata, N., Michael, N., Siccoli, M., Rogers, A., Hwang, W.-T., Scott, L., Dean, G., Geissler, E., Ametamey, S., Treyer, V., Wyss, M., Achermann, P., Schubiger, P., Theorell-Haglöw, J., Berne, C., Janson, C., Svensson, M., Lindberg, E., Caruso, H., Avinash, D., Minkel, J., Thompson, C., Wisor, J., Gerashchenko, D., Smith, K., Kuan, L., Pathak, S., Hawrylycz, M., Jones, A., Kilduff, T., Bergamo, C., Ecker, A., William, J., Niyogi, S., Coble, M., Goel, N., Lakhtman, L., Horswill, M., Whetton, M., Chambers, B., Signal, L., van Den Berg, M., Gander, P., Polotsky, V., Savransky, V., Bevans, S., Nanayakkara, A., Li, J.-G., Smith, P., Torbenson, M., Stockx, E., Brodecky, V., Berger, P., Chung-Mei Lam, J., Rial, R., Roca, C., Garau, C., Akaarir, M., Mccoy, J., Ward, C., Connolly, N., Tartar, J., Brown, R., Carberry, J., Bradford, A., O’Halloran, K., Mcguire, M., Nacher, M., Serrano-Mollar, A., Navajas, D., Farre, R., Montserrat, J., Fenik, V., Rukhadze, I., Kubin, L., Sivertsen, B., Overland, S., Mykletun, A., Czira, M., Fornádi, K., Lindner, A., Szeifert, L., Szentkirályi, A., Mucsi, I., Molnár, M., Novák, M., Zoller, R., Chin, K., Takegami, M., Oga, T., Nakayama-Asida, Y., Wakamura, T., Mishima, M., Fukuhara, S., Shepherd, K., Keir, G., Rixon, K., Makarie-Rofail, L., Unger, G., Svanborg, E., Harder, L., Sarberg, M., Broström, A., Josefsson, A., Herrera, A., Aguilera, L., Diaz, M., Fedson, A., Hung, J., Williams, C., Love, G., Middleton, S., Vermeulen, W., Middleton, P., Steinfort, D., Goldin, J., Eritaia, J., Dionysopoulos, P., Irving, L., Ciftci, T. U., Kokturk, O., Demirtas, S., Kanbay, A., Tavil, Y., Bukan, N., Demritas, S., Olsen, S., Douglas, J., Oei, T., Williams, S., Leung, S., Starmer, G., Lee, R., Chan, A., Dungan, G., Cistulli, P., Zeng, B., Bansal, A., Patial, K., Vijayan, V. K., Sonka, K., Fialova, L., Svarcova, J., Volna, J., Jiroutek, P., Pretl, M., Bartos, A., Hasegawa, R. A., Sasanabe, R., Nomura, A., Morita, M., Hori, R., Ohkura, Y., Shiomi, T. T., Collins, A., Jerums, G., Hare, D., Panagiotopoulos, S., Weatherhead, B., Bailey, M., Neil, C., Goldsworthy, U., Hill, C., Valencia-Flores, M., Resendiz, M., Juarez, S., Castano, A., Santiago, V., Aguilar, C., Ostrosky, F., Krum, H., Kaye, D., Neves, C., Decio, M., Monteiro, M., Cintra, F., Poyares, D., Viegas, C., Silva, C., Oliveira, H., Peixoto, T., Mikami, A., Watanabe, T., Kumano-Go, T., Adachi, H., Sugita, Y., Takeda, M., Oktay, B., Firat, H., Akbal, E., Ardic, S., Paim, S., Santos, R., Barrreto, A., Whitmore, H., Imperial, J., Temple, K., Rue, A., Hoffman, L., Liljenquist, D., Kazsa, K., Pavasovic, M., Copland, J., Ho, M., Jayamaha, J., Peverill, R., Hii, S., Hensley, M., Rowland, S., Windler, S., Johansson, M., Eriksson, P., Peker, Y., Råstam, L., Lindblad, U., Grote, L., Zou, D., Radlinski, J., Eder, D., Plens, C. M., Garcia Gonzaga, F. M., Farias Sa, P., Franco Oliveira, L. V., Faria Sa, P., Yoon, I.-Y., Chung, S., Hee Lee, C., Kim, J.-W., Faludi, B., Wang, X., Li, Q., Wan, H., Li, M., Pallayova, M., Donic, V., Tomori, Z., Ioacara, S., Olech, T., Mccallum, C., Bowes, M., Bowes, J., Chia, M., Gilbert, S. S., Sajkov, D., Teichtahl, H., Stevenson, I., Cunnington, D., Kalman, J., Szaboova, E., Higami, S., Kryger, M., Higami, Y., Suzuki, C., Kitano, H., Carin, S., Olof, S., Yngve, G., Gösta, B., Carlberg, B., Stenlund, H., Franklin, K. A., Oliveira, A., Vasconcelos, L., Martinez, D., Goncalves, S. C., Gus, M., Silva, E. O. A., Fuchs, S. C., Fuchs, F. D., Li, A., Au, J., Ho, C., Sung, R., Wing, Y., Tada, H., Terada, N., Togawa, K., Nakagawa, Y., Kishida, K., Kihara, S., Hirata, A., Sonoda, M., Nishizawa, H., Nakamura, T., Shimomura, I., Funahashi, T., Andrewartha, P., Sasse, A., Becker, M., Troester, N., Olschewski, H., Lisamayerkard, L., Glos, M., Blau, A., Peter, J.-G., Chesworth, W., Wilson, G., Piper, A., Chuang, L.-P., Lin, S.-W., Wang, C.-J., Li, H.-Y., Chou, Y.-T., Fu, J.-Y., Liao, Y.-F., Tsai, Y.-H., Chan, K., Laks, L., Nishibayashi, M., Miyamoto, M., Miyamoto, T., Hirata, K., Hoever, P., De Haas, S., Chiossi, E., Van Gerven, J., Dingemanse, J., Winkler, J., Cavallaro, M., Narui, K., Kasai, T., Dohl, T., Takaya, H., Kawana, F., Ueno, K., Panjwani, U., Thakur, L., Anand, J. P., Banerjee, P. K., Leigh, M., Paduch, A., Armstrong, J., Sampson, D., Kotajima, F., Mochizuki, T., Lorr, D., Harder, H., Chesworth, M., Becker, H., Abd-Elaty, N. M., Elprince, M., Ismail, N., Elserogi, W., Yeo, A., George, K., Thomson, K., Stadler, D., Bradley, J., Paul, D., Schwartz, A., Hagander, L., Harlid, R., Hultcrantz, E., Haraldsson, P., Cho, J.-G., Narayan, J., Nagarajah, M., Perri, R., Johnson, P., Burgess, K., Chau, N., Mcevoy, R. D., Arnardottir, E. S., Thorleifsdottir, B., Olafsson, I., Gislason, T., Tsuiki, S., Fujimatsu, S., Munezawa, T., Sato, Y., Subedi, P., Ainslie, P., Topor, Z., Whitelaw, W., Chan, M., So, H., Lam, H., Ng, S., Chan, I., Lam, C., Saigusa, H., Higurashi, N., He, Z. M., Cui, X. C., Li, J., Dong, X., Lv, Y., Zhou, M., Han, X., An, P., Wang, L., Macey, P. M., Serber, S., Cross, R., Yan-Go, F., Marshall, M., Rees, D., Lee, S. H., Ho Cho, J. I., Shin, C., Lee, J. Y., Kwon, S. Y., Kim, T.-H., Vedam, H., Barnes, D., Walter, H., Karin, J., Hermann, P., Belyavskiy, E., Galitsyn, P., Arbolishvili, G., Litvin, A., Chazova, I., Mareev, V., Ramar, K., Khan, A., Gay, P., Strömberg, A., Ulander, M., Fridlund, B., Mårtensson, J., Yee, B., Desai, A., Buchanan, P., Crompton, R., Melehan, K., Wong, P., Tee, A., Ng, A., Darendeliler, M. A., Ye, L., Maislin, G., Hurley, S., Mccluskey, S., Weaver, T., Yun, C.-H., Ji, K.-H., Ahn, J. Y., Lee, H.-W., Zhang, X., Yin, K., Zhaofang, G., Chong, L., Navailles, B., Zenou, E., Cheze, L., Pignat, J.-C., Tang, T., Remmers, J., Vasilakos, K., Denotti, A., Gilholme, J., Castronovo, V., Marelli, S., Aloia, M., Fantini, M. L., Kuo, T., Manconi, M., Zucconi, M., Ferini-Strambi, L., Livia Fantini, M., Giarolli, L., Oldani, A., Lee, Y., Trenell, M., Berend, N., Wang, M., Liang, Z., Lei, F., Komada, I., Nishikawa, M., Sriram, K., Mignone, L., Antic, R., Fujiwara, K., Beaudry, M., Gauthier, L., Laforte, M., Lavigne, G., Wylie, P., Orr, W., Grover, S., Geisler, P., Engelke, E., Cossa, G., Veitch, E., Brillante, R., Mcardle, N., Murphy, M., Singh, B., Gain, K., Maguire, C., Mutch, S., Brown, S., Asciuto, T., Newsam, C., Fransson, A., Ísacsson, G., Tsou, M.-C., Hsu, S.-P., Almendros, I., Acerbi, I., Vilaseca, I., Dcruz, O., Vaughn, B., Muenzer, J., Lacassagne, L., Montemayor, T., Roch-Paoli, J., Qian, J., Petocz, P., Chan, M. R., Munro, J., Zimmerman, M., Stanchina, M., Millman, R., Cassel, W., Ploch, T., Loh, A., Koehler, U., Jerrentrup, A., Greulich, T., Doyle, G., Pascoe, T., Jorgensen, G., Baglioni, C., Lombardo, C., Espie, C., Violani, C., Edell-Gustafsson, U., Swahn, E., Ejdeback, J., Tygesen, H., Johansson, A., Neckelmann, D., Hilde Nordhus, I., Zs-Kovács, Á., Vámos, E., Zs-Molnár, M., Maisuradze, L., Gugushvili, J., Darchia, N., Gvilia, I., Lortkipanidze, N., Oniani, N., Wang-Weigand, S., Mayer, G., Roth-Schechter, B., Hsu, S.-C., Yang, C.-M., Liu, C.-Y., Ito, H., Omvik, S., Nordhus, I. H., Farber, R., Scharf, M., Harris-Collazo, R., Pereira, J., Andras, S., Ohayon, M., David, B., Morgan, K., Voorn, T., Vis, J., Kuijer, J., Fortier-Brochu, E., Beaulieu-Bonneau, S., Ivers, H., Morin, C., Beaulieu-Benneau, S., Harris, J., Bartlett, D., Paisley, L., Moncada, S., Toelle, B., Bonnet, M. H., Arand, D., Bonnet, J., Bonnet, M., Doi, Y., Edéll-Gustafsson, U., Strijers, R., Fernando, A., Arroll, B., Warman, G., Funakura, M., Shikano, S., Unemoto, Y., Fujisawa, M., Hong, S.-C., Jeong, J.-H., Shin, Y.-K., Han, J.-H., Lee, S.-P., Lee, J.-H., Mignot, E., Nakajima, T., Hayashida, K., Honda, M., Ardestani, P., Etemadifar, M., Nejadnik, H., Maghzi, A. H., Basiri, K., Ebrahimi, A., Davoodi, M., Peraita-Adrados, R., Vicario, J. L., Shin, H.-B., Marti, I., Carriero, L., Fulda, S., Beitinger, P., Pollmacher, T., Lam, J. S. P., Fong, S. Y. Y., Tang, N. L. S., Ho, C. K. W., Li, A. M. C., Wing, Y. K., Guilleminault, C., Black, J., Wells, C., Kantor, S., Janisiewicz, A., Scammell, T., Tanaka, S., Smith, A., Neufing, P., Gordon, T., Fuller, P., Gompf, H., Pedersen, N., Saper, C., Lu, J., Sasai, T., Donjacour, C., Fronczek, R., Le Cessie, S., Lammers, G. J., van Dijk, J. G., Hayashi-Ogawa, Y., Okuda, M., Lam, V. K.-H., Chen, A. L., Ho, C. K.-W., Wing, Y.-K., Lehrhaft, B., Brilliante, R., van Der Zande, W., Overeem, S., van Dijk, G., Lammers, J. G., Opazo, C. J., Jeong, D.-U., Sung, Y. H., Lyoo, I. K., Takahashi, Y., Murasaki, M., Bloch, K., Jung, H., Dahab, M. M., Campos, T. F., Mccabe, S., Maravic, K., Wiggs, L., Connelly, V., Barnes, J., Saito, Y., Ogawa, M., Murata, M., Nadig, U., Rahman, A., Aritake, K., D’Cruz, O., Suzuki, K., Kaji, Y., Takekawa, H., Nomura, T., Yasui, K., Nakashima, K., Bahammam, A., Rab, M. G., Owais, S., Alsuwat, K., Hamam, K., Zs, M., Boroojerdi, B., Giladi, N., Wood, D., Sherman, D., Chaudhuri, R., Partinen, M., Abdo, F., Bloem, B., Kremer, B., Verbeek, M., Cronlein, T., Mueller, U., Hajak, G., Zulley, J., Namba, K., Li, L., Mtsuura, M., Kaneita, Y., Ohida, T., Cappeliez, B., Moutrier, R., De, S., Dwivedi, S., Chambers, D., Gabbay, E., Watanabe, A., Valle, C., Kauati, A., Watanabe, R., Chediek, F., Botte, S., Azevedo, E., Kempf, J., Cizza, G., Torvik, S., Brancati, G., Smirne, N., Bruni, A., Goff, E., Freilich, S., Malaweera, A., Simonds, A., Mathias, C., Morrell, M., Rinsky, B., Fonarow, G., Gradinger, F. P., Boldt, C., Geyh, S., Stucki, A., Dahlberg, A., Michel, F., Savard, M.-H., Savard, J., Quesnel, C., Hirose, K., Takahara, M., Mizuno, K., Sadachi, H., Nagashima, Y., Yada, Y., Cheung, C.-F., Lau, C., Lai, W., Sin, K., Tam, C., Hellgren, J., Omenaas, E., Gíslason, T., Jögi, R., Franklin, K., Torén, K., Wang, F., Kadono, M., Shigeta, M., Nakazawa, A., Ueda, M., Fukui, M., Hasegawa, G., Yoshikawa, T., de Niet, G., Tiemens, B., Lendemeijer, B., Hutschemaekers, G., Gauthier, A.-K., Chevrette, T., Chevrier, E., Bouvier, H., Parry, B., Meliska, C., Nowakowski, S., Lopez, A., Martinez, F., Sorenson, D., Lien, M. L., Lattova, Z., Maurovich-Horvat, E., Nia, S., Pollmächer, T., Poulin, J., Chouinard, S., Stip, E., Guillem, F., Venne, D., Caouette, M., Lamont, M.-E., Lázár, A., Lázár, Z., Bíró, A., Gyõri, M., Tárnok, Z., Prekop, C., Gádoros, J., Halász, P., Bódizs, R., Okun, M., Hanusa, B., Hall, M., Wisner, K., Pereira, M., Kumar, R. A. J. E. S. H., Macey, P. A. U. L., Woo, M. A. R. Y., Serber, S. T. A. C. Y., Valladares, E. D. W. I. N., Harper, R. E. B. E. C. C. A., Harper, R. O. N. A. L. D., Puttonen, S., Härmä, M., Vahtera, J., Kivimäki, M., Lamarche, L., Hemmeter, U. M., Thum, A., Rocamora, R., Giesler, M., Haag, A., Dodel, R., Krieg, J. C., Shechter, A., L’Esperance, P., Boivin, D. B., Vu, M.-T., and Richards, H.
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- 2007
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7. Symposia Abstracts
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Siegel, Jerome M., Murillo-Rodriguez, Eric, Xu, Man, Lin, Ling, Gerashchenko, Dmitry, Blanco-Centurion, Carlos, Shiromani, Anjelica, Nishino, Seiji, Mignot, Emmanuel, Shiromani, Priyattam J., Alam, Md Noor, John, Joshi, Wu, Ming-Fung, Boehmer, Lisa N., Lack, Leon, Harris, Jodie, Mercer, Jeremy D., Bootzin, Richard R., Lack, Leon C., Britton, Willoughby B., Fridel, Keith W., Payne, Jessica, Stevens, Sally J., Shapiro, Shauna L., Cousins, Jennifer C., Hasler, Brant P., Bailey, Elaine T., Hitt, Sabrina, Estrada, Barbara, Cameron, Michael, Velluti, Ricardo A., Voss, Ursula, Coenen, Anton M. L., Campbell, Kenneth, Gulia, Kamalesh K., Mallick, Hruda Nanda, Kumar, Velayudhan Mohan, Schmidt, Markus H., Andersen, Monica L., Velazquez-Moctezuma, Javier, Gulia, Kamalesh Kumari, Koyama, Y., Takahashi, K., Toledo, C., Kayama, Y., Iwasaki, H., Kawauchi, A., Miki, T., Schmidt, M. H., Anna, Szucs, Kotchabhakdi, Naiphinich, Kotchabhakdi, Nittaya J., Allen, Richard P., Hening, Wayne A., Walters, Arthur, Walters, Arthur S., de Valck, Elke, Quanten, Stijn, Cluydts, Raymond, Berckmans, Daniël, Weaver, Terri E., Härmä, Mikko, Grunstein, Ron, Lavie, Lena, Sharma, Anuja, Lavie, Peretz, Luppi, Pierre-Hervé, Goutagny, Romain, Verret, Laure, Gervasoni, Damien, Boissard, Romuald, Lapray, Damien, Salvert, Denise, Léger, Lucienne, Peyron, Christelle, Fort, Patrice, Mallick, Birendra N., Mccarley, Robert W., Brown, Ritchie, Thakkar, Mahesh, Naidoo, Nirinjini, Datta, Subimal, Ramesh, Vijay, Basheer, Radhika, Urade, Yoshihiro, Opp, Mark R., Adrien, Joëlle, Yamuy, J., Borde, M., Xi, M., Fung, S. J., Sampogna, S., Ramos, O., Torterolo, P., Chase, M. H., Marks, Gerald A., Saaresranta, Tarja, Mccrimmon, Donald R., Alheid, George F., Kubin, Leszek, Radulovacki, Miodrag, Murck, Harald, Auer, Dorothea, Kuenzel, Heike, Held, Katja, Antonijevic, Irina A., Steiger, Axel, Edith, Holsboer-Trachsler, Martin, Hatzinger, Ulrich, Hemmeter, Schüssler, Petra, Uhr, Manfred, Yassouridis, Alexander, Askenasy, Jean, Spencer, Kevin, Siegal, Jerome M., Kobayashi, Toshinori, Ishikawa, Tohru, Tomita, Shinichi, Yoshida, Hironori, Arakawa, Kazunari, Kutty, Bindu M., Honma, Ken-Ichi, Yamanaka, Yujiro, Miyazaki, Toshihiko, Hashimoto, Satoko, Honma, Sato, Youngstedt, S. D., Mukai, Junko, Uchida, Sunao, Dinges, David F., van Dongen, Hans P. A., Gazendam, Joost A. C., Schwab, Richard J., Parthasarathy, Sairam, Kalinchuk, Anna, Porkka-Heiskanen, Tarja, Stakofsky, Allisonb, Chee, Michael, Choo, Wei-Chieh, Chan, Wai-Yen, Chuah, Lisa, Sze, Joanna, Shen, Li-Juan, Vijayan, V. K., Monie, Robert, Edwards, Susan, Shrivastava, Deepak, Goswami, Meeta, Honig, Eveline, Cloud, Robert L., Bhuvaneshwari Bhagat, M. S. K., Selvamurthy, W., Lovering, Andrew T., Fraigne, Jimmy J., Dunin-Barkowski, Witali L., Vidruk, Edward H., Orem, John M., Panjwani, Usha, Thakur, L., Anand, J. P., Banerjee, P. K., Mckenna, James, Ward, Chris, Tartar, Jaime, Strecker, Robert, Zhan, G.-X., Serrano, F., Fenik, P., Hsu, R., Kong, L., Pratico, D., Klann, E., Veasey, S. C., Fenik, Victor B., Volgin, Denys V., Swan, Jennifer L., Davies, Richard O., Row, Barry W., Huang, Zhi-Li, Mochizuki, Takatoshi, Qu, Wei-Min, Hayaishi, Osamu, Eguchi, Naomi, Yamanaka, Akihiro, Sakurai, Takeshi, Gallopin, Thierry, Vivaldi, Ennio A., Ocampo-Garcés, Adrián, Bassi, Alejandro, Bon, Olivier Le, Amici, Roberto, Baracchi, Francesca, Capitani, Paolo, Cerri, Matteo, Dentico, Daniela, Jones, Christine Ann, Luppi, Marco, Parmeggiani, Pier Luigi, Perez, Emanuele, and Zamboni, Giovanni
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- 2005
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8. Reduced exercise capacity in non-cystic fibrosis bronchiectasis
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Swaminathan, Soumya, Kuppurao, K. V., Somu, N., and Vijayan, V. K.
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- 2003
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9. Clinical aspects of tuberculosis
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Vijayan, V. K.
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- 2002
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10. ERYTHROCYTE MEMBRANE LIPID ANALYSIS IN COPD PATIENTS IN A NORTH INDIAN SETUP: 174
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GANGOPADHYAY, S, VIJAYAN, V K, and BANSAL, S K
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- 2011
11. Role of Mycoplasma pneumoniae infection in acute exacerbations of chronic obstructive pulmonary disease
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Varma-Basil, Mandira, Dwivedi, Shailendra K. D., Kumar, Krishna, Pathak, Rakesh, Rastogi, Ritika, Thukral, S. S., Shariff, Malini, Vijayan, V. K., Chhabra, Sunil K., and Chaudhary, Rama
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- 2009
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12. A CASE OF PRIMARY PULMONARY BOTRYOMYCOSIS IN A PATIENT WITHOUT ANY UNDERLYING ILLNESS
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Sayal, Pankaj, Kulshrestha, Ritu, and Vijayan, V K.
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- 2006
13. PREVALENCE OF OBSTRUCTIVE SLEEP APNEA SYNDROME (OSAS) IN DELHI, INDIA
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Vijayan, V K. and Patial, K
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- 2006
14. Possible role of free radicals in theophylline-induced seizures in mice
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Gulati, Kavita, Ray, Arunabha, Pal, Giridhari, and Vijayan, V. K.
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- 2005
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15. Pharmacological and biochemical studies on the possible role of nitric oxide in stress adaptation in rats
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Masood, Anbrin, Banerji, Basudeb, Vijayan, V. K., and Ray, Arunabha
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- 2004
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16. Cellular profile of bronchoalveolar lavage fluid in pulmonary tuberculosis
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Swaminathan, Soumya, Venkatesan, P., Sankaran, K., Prabhakar, R., Vijayan, V. K., Somu, N., and Vijayasekaran, D.
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- 1995
17. Persistent Lower Respiratory Tract Inflammation Associated with Interstitial Lung Disease in Patients with Tropical Pulmonary Eosinophilia following Conventional Treatment with Diethylcarbamazine
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Rom, W. N., Vijayan, V. K., Cornelius, M. J., Kumaraswami, V., Prabhakar, R., Ottesen, E. A., and Crystal, R. G.
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- 1990
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18. Consensus & Evidence-based INOSA Guidelines 2014 (First edition)
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Sharma, S. K., Katoch, V. M., Mohan, A., Kadhiravan, T., Elavarasi, A., Ragesh, R., Nischal, N., Sethi, P., Behera, D., Bhatia, M., Ghoshal, A. G., Gothi, D., Joshi, J., Kanwar, M. S., Kharbanda, O. P., Kumar, S., Mohapatra, P. R., Mallick, B. N., Mehta, R., Prasad, R., Sharma, S. C., Sikka, K., Sandeep Aggarwal, Shukla, G., Suri, J. C., Vengamma, B., Grover, A., Vijayan, V. K., Ramakrishnan, N., Gupta, R., and Indian Initiative on Obstructive Sleep Apnoea Guidelines Working Group
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stomatognathic system ,lcsh:R ,lcsh:Medicine ,Bariatric surgery - CPAP - Indian guidelines - OSA - OSAS - polysomnography - sleep apnoea - sleep study - Syndrome Z ,nervous system diseases ,respiratory tract diseases - Abstract
Obstructive sleep apnoea (OSA) and obstructive sleep apnoea syndrome (OSAS) are subsets of sleep-disordered breathing. Awareness about OSA and its consequences amongst the general public as well as the majority of primary care physcians across India is poor. This necessiated the development of the INdian initiative on Obstructive sleep apnoea (INOSA) guidelines under the auspices of Department of Health Research, Ministry of Health & Family Welfare, Government of India. OSA is the occurrence of an average five or more episodes of obstructive respiratory events per hour of sleep with either sleep related symptoms or co-morbidities or ≥ 15 such episodes without any sleep related symptoms or co-morbidities. OSAS is defined as OSA associated with daytime symptoms, most often excessive sleepiness. Patients undergoing routine health check-up with snoring, daytime sleepiness, obesity, hypertension, motor vehicular accidents and high risk cases should undergo a comprehensive sleep evaluation. Medical examiners evaluating drivers, air pilots, railway drivers and heavy machinery workers should be educated about OSA and should comprehensively evaluate applicants for OSA. Those suspected to have OSA on comprehensive sleep evaluation should be referred for a sleep study. Supervised overnight polysomnography (PSG) is the "gold standard" for evaluation of OSA. Positive airway pressure (PAP) therapy is the mainstay of treatment of OSA. Oral appliances are indicated for use in patients with mild to moderate OSA who prefer oral appliances to PAP, or who do not respond to PAP or who fail treatment attempts with PAP or behavioural measures. Surgical treatment is recommended in patients who have failed or are intolerant to PAP therapy.
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- 2014
19. Tropical Pulmonary Eosinophilia: Analysis of Antifilarial Antibody Localized to the Lung
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Nutman, Thomas B., Vijayan, V. K., Pinkston, Paula, Kumaraswami, V., Steel, Cathy, Crystal, Ronald G., and Ottesen, Eric A.
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- 1989
20. Short Course Chemotherapy For Tuberculous Lymphadenitis In Children
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Jawahar, M. S., Sivasubramanian, S., Vijayan, V. K., Ramakrishnan, C. V., Paramasivan, C. N., Selvakumar, Vanaja, Paul, Sare, Tripathy, S. P., and Prabhakar, R.
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- 1990
21. Statement on publishing clinical trials in Indian biomedical journals
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Satyanarayana, K., Sharma, Anju, Parikh, Purvish, Vijayan, V. K., Sahu, D. K., Nayak, Barun K., Gulati, R. K., Parikh, Mahendra N., Singh, Prati Pal, Bavdekar, S. B., Sreehari, U., and Sahni, Peush
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- 2008
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22. LUNG FUNCTION IN NORMAL INDIAN CHILDREN AGED 7 TO 19 YEARS
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Vijayan, V K. and Reetha, A M.
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Pulmonary function tests -- Analysis ,Pediatric respiratory diseases -- Care and treatment ,Health ,Care and treatment ,Analysis - Abstract
V K Vijayan(*) and A M Reetha. VP Chest Institute, University of Delhi, Delhi and Malaria Research Centre, Delhi, India. PURPOSE: The currently available regression equations to predict lung function [...]
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- 2000
23. IVERMECTIN IN THE TREATMENT OF TROPICAL EOSINOPHILIA
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Vijayan, V. K.
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Ivermectin -- Health aspects ,Eosinophilia -- Drug therapy ,Health ,Drug therapy ,Health aspects - Abstract
V K Vijayan(*). VP Chest Institute, University of Delhi, Delhi, India. PURPOSE: Tropical eosinophilia (TE) results from a heightened immunologic response to the human filarial parasite. TE therefore, responds to [...]
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- 2000
24. A study on the correlation of matrix metalloproteinase MMP1 in COPD and smoking in the North Indian population.
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Rohil, Vishwajeet, Vijayan, V. K., Kumar, Raj, Joshi, Rini, Pavani, P., Paul, Shweta, Sharma, Anju, and ur Rahman, Mujeeb
- Subjects
- *
OBSTRUCTIVE lung diseases , *TOBACCO smoke , *METALLOPROTEINASES , *PSYCHOLOGY - Abstract
Background: Chronic Obstructive Pulmonary Disease (COPD) is characterized by airway obstruction and destruction of lung tissue, the disease for which at present there is no cure, although the treatment can slow worsening. Nearly 90% of COPD is caused by long term cigarette smoking; however, only 25% of chronic tobacco smokers develop COPD, the exact cause of this predisposition of some smokers to acquire COPD is still poorly understood at the molecular level. Lot of studies are available showing the correlation of MMP1 and asthma but not much work has been done on its correlation with COPD especially in North India. The outcome of our study was also expected to discover MMP1 as a new target for treating COPD and its progression in smokers. Aims and Objectives: The association of COPD and smoking with MMP1 gene product and SNP in the North Indian population was intended to be studied. Material and Methods: The proposed study was a case control study. In this study adults aged 30 years and above fulfilling the inclusion criteria (the criteria mentioned under the materials and methods) were considered and a total of 180 subjects were taken after determining the sample size. Pulmonary function test (PFT) was performed by Spirometry. Three main groups each consisting of 60 subjects were formed on the basis of smoking history and Spirometry: Ist group: Smokers without co-morbidity with normal PFT, IInd group: Smokers with Spirometry proved COPD and without any other co-morbidity, IIIrd group: Healthy Non-smoker controls. Quantification of metalloproteinase MMP1 in all the groups were performed in the serum with ELISA kits and Single Nucleotide Polymorphism (SNP 1G-1607 2G, ID rs1799750) studiesin the gene encoding MMP1 linked to COPD susceptibility in smokers was performed by DNA Sequencing Analysis. The correlation between the SNPs, gene product, smokingand COPD was studied. Results: MMP1 concentration was seen increased in serum of COPD and smokers when compared to healthy controls. And there is high negative correlation between *FEV1/FVC % (post-bronchodilator)and MMP1 in COPD compared to Smokers and Healthy Controls. However, from the results of present analysis, we could show negative correlation between MMP1 and *FEV1/FVC % in all the 3 groups but the correlation proves to be much more negative in Group II i.e. Smokers with COPD. Statistically Significant Positive Correlation of Pack Years with MMP1 conc., and Statistically Significant Negative Correlation between Pack Years and *FEV1/FVC % was seen. Conclusion: In conclusion, our present analyses did show significant association between MMP1 and COPD risk in North Indian population. MMP1 levels of COPD patients were significantly increased in smokers and may contribute to or be a marker of the pathophysiology of COPD. [ABSTRACT FROM AUTHOR]
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- 2017
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25. Evaluation of Therapeutic Efficacy of Ascorbic Acid in Patients with Bronchial Asthma.
- Author
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Akhtar, Razi, Jain, Sandeep, Kumar, Abhishek, Bhatia, Saurabh, Joshi, Jagdish C., Singh, Dhirendra, Shamsuzzaman, Md, Sharma, Meenakshi, Pal, Giridhari, Vijayan, V. K., Gaur, S. N., Gulati, Kavita, and Ray, Arunabha
- Subjects
ASTHMA ,OBSTRUCTIVE lung diseases ,VITAMIN C ,RESPIRATORY therapist & patient ,MEDICAL care ,SICK people - Abstract
Background: Asthma is a chronic inflammatory airway disease and oxidative stress may be involved in its pathogenesis. The present study aims at evaluating the therapeutic effects of antioxidant drug Ascorbic Acid (Vitamin C) in patients of Bronchial Asthma. Method: Patients of Bronchial asthma from outpatient facility of our institute were enrolled for the study and divided into study and control group. Both groups were given inhaled fluticasone and salmeterol and oral theophylline. Ascorbic acid was given in the study group. Each patient was followed up weekly for the assessment of efficacy parameters using pulmonary function test (PFT), clinical symptoms and emergency drug use. Oxidative stress parameters were assessed through the estimation of malondialdehyde levels and superoxide dismutase activity in the above two patient groups. Results: Although there was statistically significant improvement in pulmonary function tests (p<0.001), clinical symptoms (p<0.05) and emergency drug use (p<0.001) in both treatment groups at the end of 4 weeks but there was no significant difference in these parameters between the two groups. There was statistically significant improvement in malondialdehyde level (p<0.001) and superoxide dismutase activity (p<0.001) in ascorbic acid group only at the end of 2 weeks and 4 weeks. Conclusion: Ascorbic Acid failed to show any significant improvement in the patient symptoms and pulmonary function tests in the study group; however it showed statistically significant improvement in the status of Oxidative Stress. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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26. Epidemiological Profile of Tobacco Users at Tobacco Cessation Centre: An Indian Experience.
- Author
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Kumar, Raj, Goel, Nitin, Kumar, Suraj, Kushwah, Alka S., and Vijayan, V. K.
- Published
- 2016
27. A TRIBUTE TO PROFESSOR AUTAR SINGH PAINTAL (1925-2004).
- Author
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BACK, NATHAN, COHEN, IRUN R., KRITCHEVSKY, DAVID, LAJTHA, ABEL, PAOLETTI, RODOLFO, Hayashida, Yoshiaki, Gonzalez, Constancio, Kondo, Hisatake, RAVI, K., and VIJAYAN, V. K.
- Abstract
Great men are the true men in whom nature has prospered. They are not extra-ordinary - they are in the true order, what they are ought to be. They reached the summit by doing their jobs in hand with everything they had of energy, enthusiasm and hard work. More importantly, they made every man who came in contact with them feel great. Autar Singh Paintal who passed away on December 21, 2004 in Delhi was indeed such a great man who will be remembered not only for his contributions in Physiology but also for his acts of altruism. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
28. Policy Document Consensus & Evidence-based INOSA Guidelines 2014 (First edition).
- Author
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Sharma, Surendra K., Elavarasi, A., Ragesh, R., Nischal, Neeraj, Sethi, Prayas, Kharbanda, O. P., Sharma, S. C., Sikka, Kapil, Aggarwal, Sandeep, Shukla, Garima, Kanwar, M. S., Kumar, Suresh, Mohapatra, P. R., Mallick, B. N., Mehta, Ravindra, Prasad, Rajendra, Suri, J. C., Vijayan, V. K., Ramakrishnan, N., and Katoch, Vishwa Mohan
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PHYSIOLOGY ,SLEEP apnea syndromes ,PATIENTS ,DISEASE risk factors - Published
- 2015
- Full Text
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29. Chronic obstructive pulmonary disease.
- Author
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Vijayan, V. K.
- Subjects
- *
AIR flow , *AIR pollution , *BRONCHODILATOR agents , *OBSTRUCTIVE lung diseases , *BRONCHITIS , *DISEASE exacerbation , *SMOKING - Abstract
The global prevalence of physiologically defined chronic obstructive pulmonary disease (COPD) in adults aged >40 yr is approximately 9-10 per cent. Recently, the Indian Study on Epidemiology of Asthma, Respiratory Symptoms and Chronic Bronchitis in Adults had shown that the overall prevalence of chronic bronchitis in adults >35 yr is 3.49 per cent. The development of COPD is multifactorial and the risk factors of COPD include genetic and environmental factors. Pathological changes in COPD are observed in central airways, small airways and alveolar space. The proposed pathogenesis of COPD includes proteinase-antiproteinase hypothesis, immunological mechanisms, oxidant-antioxidant balance, systemic inflammation, apoptosis and ineffective repair. Airflow limitation in COPD is defined as a postbronchodilator FEV1 (forced expiratory volume in 1 sec) to FVC (forced vital capacity) ratio <0.70. COPD is characterized by an accelerated decline in FEV1. Co morbidities associated with COPD are cardiovascular disorders (coronary artery disease and chronic heart failure), hypertension, metabolic diseases (diabetes mellitus, metabolic syndrome and obesity), bone disease (osteoporosis and osteopenia), stroke, lung cancer, cachexia, skeletal muscle weakness, anaemia, depression and cognitive decline. The assessment of COPD is required to determine the severity of the disease, its impact on the health status and the risk of future events (e.g., exacerbations, hospital admissions or death) and this is essential to guide therapy. COPD is treated with inhaled bronchodilators, inhaled corticosteroids, oral theophylline and oral phosphodiesterase-4 inhibitor. Non pharmacological treatment of COPD includes smoking cessation, pulmonary rehabilitation and nutritional support. Lung volume reduction surgery and lung transplantation are advised in selected severe patients. Global strategy for the diagnosis, management and prevention of Chronic Obstructive Pulmonary Disease guidelines recommend influenza and pneumococcal vaccinations. [ABSTRACT FROM AUTHOR]
- Published
- 2013
30. Down the memory lane: Lung India three decades.
- Author
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Jindal, S. K., Shankar, P. S., Vijayan, V. K., Kamat, S. R., and Deivanayagan, C. N.
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PULMONARY function tests ,DISEASE incidence ,PULMONARY aspergillosis - Abstract
An introduction is presented in which the editor discusses various reports within the issue on topics including pulmonary function test, incidence of lung cancer, and allergic bronchopulmonary aspergillosis.
- Published
- 2012
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31. Role of a Pattern-based Approach in Interpretation of Transbronchoscopic Lung Biopsy and Its Clinical Implications.
- Author
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Kulshrestha, Ritu, Menon, B. K., Rajkumar, and Vijayan, V. K.
- Published
- 2012
32. Regression Equations for Spirometry in Children Aged 6 to 17 Years in Delhi Region.
- Author
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Chhabra, S. K., Vijayan, V. K., Rahman, M., Mittal, V., and Singh, P. D.
- Published
- 2012
33. Breath Carbon Monoxide Level of Non-Smokers Exposed to Environmental Tobacco Smoke.
- Author
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Kumar, Raj, Mahakud, Gopal C., Nagar, Jitendra K., Singh, S. P., Raj, N., Gopal, K., and Vijayan, V. K.
- Published
- 2011
34. Anti-Oxidant Treatment in Obstructive Sleep Apnoea Syndrome.
- Author
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Sadasivam, K., Patial, K., Vijayan, V. K., and Ravi, K.
- Published
- 2011
35. Systemic Inflammation and Its Response to Treatment in Patients With Asthma.
- Author
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Girdhar, Ankur, Kumar, Vivek, Singh, Amita, Menon, Balakrishnan, and Vijayan, V. K.
- Subjects
ADRENERGIC beta agonists ,ADRENOCORTICAL hormones ,HORMONE therapy ,ANALYSIS of variance ,ASTHMA ,BLOOD sedimentation ,C-reactive protein ,CHI-squared test ,COMPUTER software ,STATISTICAL correlation ,INFLAMMATION ,LEUCOCYTES ,PROBABILITY theory ,RESPIRATORY measurements ,SPIROMETRY ,STATISTICS ,T-test (Statistics) ,U-statistics ,DATA analysis ,MULTIPLE regression analysis ,BODY mass index ,VITAL capacity (Respiration) ,THERAPEUTICS - Abstract
BACKGROUND: Asthma is an obstructive airway disease characterized by airway inflammation. OBJECTIVE: To measure systemic inflammation in asthma patients, and to assess the effect of treatment on systemic inflammation. METHODS: In 30 newly diagnosed non-randomized adult asthma patients we measured systemic inflammation markers (serum high-sensitivity C-reactive protein, total leukocyte count, and erythrocyte sedimentation rate) before and after a 6-week standard treatment with inhaled steroids and inhaled β
2 agonist. The comparison group comprised 20 healthy control subjects. All the subjects were non-smokers. RESULTS: The measured systemic inflammation markers were higher in the asthma patients: high-sensitivity C-reactive protein 4.8 ± 6.0 mg/dL vs 1.5 ± 1.4 mg/dL, P < .001; total leukocyte count 8,936 ± 2,592 cells/µL versus 7,741 ± 1,924 cells/µL, P < .001; erythrocyte sedimentation rate 24.8 ± 12.3 mm/h versus 15.3 ± 6.5 mm/h, P < .001. In the asthma patients, high-sensitivity C-reactive protein negatively correlated with percent-of-predicted FEV1 (r = −0.64, P = .001), percent-of-predicted forced vital capacity (FVC) (r = −0.39, P = .03), FEV1 / FVC% (r = −0.71, P < .001), and percent-of-predicted forced expiratory flow during the middle half of the FVC maneuver (FEF25-75 ) (r = −0.51, P = .004). Total leukocyte count negatively correlated with percent-of-predicted FEV1 (r = −0.64, P = .001), percent-of-predicted FEV1 /FVC (r = −0.74, P<.001), and percent-of-predicted FEF25-75 (r = −0.58, P = .001). Body mass index positively correlated with high-sensitivity C-reactive protein (r = 0.65, P < .001). Multiple linear regression showed significant correlation of high-sensitivity C-reactive protein (r2 = 0.75) with age (β = 0.31, P = .008), body mass index (β = 0.99, P = .001), family size (β = 0.33, P = .008), and weight (β = −0.45, P = .01). The systemic inflammation markers decreased significantly (P < .001 for all comparisons) after 6 weeks of treatment: high-sensitivity C-reactive protein decreased from 4.8 ± 6.0 mg/dL to 2.4 ± 5.4 mg/dL, total leukocyte count decreased from 8,936 ± 2,592 cells/µL to 6,960 ± 1,785 cells/µL, and erythrocyte sedimentation rate decreased from 24.8 ± 12.3 mm/h to 15.8 ± 10.1 mm/h. CONCLUSIONS: Inhaled steroids plus inhaled β2 agonist significantly reduced systemic inflammation in asthma patients. [ABSTRACT FROM AUTHOR]- Published
- 2011
- Full Text
- View/download PDF
36. Evaluation of peptone glucose fluconazole agar as a selective medium for rapid and enhanced isolation of Aspergillus fumigatus from the respiratory tract of bronchopulmonary aspergillosis patients colonized by Candida albicans.
- Author
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Randhawa, H. S., Chowdhary, Anuradha, Sinha, K. Preeti, Kowshik, T., and Vijayan, V. K.
- Subjects
PEPTONES ,GLUCOSE ,SPUTUM ,FUNGI ,BRONCHOALVEOLAR lavage ,ASPERGILLUS - Abstract
We have reported earlier that Aspergillus fumigatus is inhibited in vitro by Candida albicans which also interferes in its isolation from sputum experimentally seeded with predetermined graded inocula of the two fungi. It was further shown that this interference was neutralized by employing peptone glucose agar with incorporation of fluconazole which is more inhibitory to C. albicans than to A. fumigatus . This communication embodies the results of evaluation of peptone glucose fluconazole agar (PGFA) as a selective culture medium for rapid and enhanced isolation of A. fumigatus from sputum of patients clinically suspected of aspergillosis with C. albicans colonization in the respiratory tract. Of the 23 sputum specimens and one broncho-alveolar lavage collected from 15 suspected aspergillosis patients, A. fumigatus was isolated from all (100%) on PGFA as against only 19 specimens (79%) that proved to be positive on the control PGA medium ( P [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
37. POLYACRYLAMIDE GEL ELECTROPHORESIS OF RAT BRAIN ACETYLCHOLINESTERASE: ISOENZYME CHANGES FOLLOWING PARATHION POISONING.
- Author
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Vijayan, V. K. and Brownson, R. H.
- Published
- 1975
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38. POLYACRYLAMIDE GEL ELECTROPHORESIS OF RAT BRAIN ACETYLCHOLINESTERASE: ISOENZYMES OF NORMAL RAT BRAIN.
- Author
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Vijayan, V. K. and Brownson, R. H.
- Published
- 1974
- Full Text
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39. Pulmonary function in healthy young adult Indians in Madras.
- Author
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Vijayan, V K, Kuppurao, K V, Venkatesan, P, Sankaran, K, and Prabhakar, R
- Subjects
LUNG physiology ,AGE distribution ,PULMONARY gas exchange ,RESPIRATORY measurements ,FORCED expiratory volume - Abstract
Forced vital capacity, forced expiratory volume in one second, functional residual capacity, residual volume, total lung capacity, and single breath diffusing capacity measurements (effective alveolar volume, carbon monoxide transfer factor, and transfer coefficient) were measured in 247 young healthy adults (130 male, 117 female) aged 15-40 years living in Madras. Subjects were of Dravidian stock, living at sea level with rice as their staple diet. Regression equations were derived for men and women for predicting normal pulmonary function for young adults in South India. The values were similar to those reported for subjects from Western India and lower than those reported for North Indians and caucasians. [ABSTRACT FROM PUBLISHER]
- Published
- 1990
40. Acetylcholinesterase activity and menstrual remissions in myasthenia gravis.
- Author
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Vijayan, N, Vijayan, V K, and Dreyfus, P M
- Subjects
ERYTHROCYTES ,ACETYLCHOLINESTERASE ,AUTOANTIBODIES ,THORACIC surgery ,ESTROGEN ,MENSTRUATION ,MYASTHENIA gravis ,MYONEURAL junction ,PROGESTERONE ,DISEASE remission - Abstract
Menstrually related temporary remissions of myasthenic symptoms are reported to occur in 25 to 50% of female patients. Even though this has been attributed to hormonal changes associated with the menstrual cycle the underlying mechanism of this hormonal influence has remained elusive. The present study demonstrated a cyclical variation in the activity of red cell acetylcholinesterase (EC 3.1.1.7) enzyme (AChE) with a marked reduction at the time of menstrual remission of symptoms of myasthenia. These cyclical changes were abolished by thymectomy. It appears, therefore, that menstrual remission in myasthenia is at least partly due to hormone-induced changes in AChE activity. This process seems to be under the control of the thymus gland. [ABSTRACT FROM AUTHOR]
- Published
- 1977
41. Brain acetylcholinesterase activity and multiplicity in the Bonnet monkey ( Macaca radiata) and the Rhesus monkey ( Macaca mulatta).
- Author
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Vijayan, V. K. and Oschowka, J. A.
- Published
- 1977
- Full Text
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42. Statement on publishing clinical trials in Indian biomedical journals.
- Author
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Satyanarayana K, Sharma A, Parikh P, Vijayan VK, Sahu DK, Nayak BK, Gulati RK, Parikh MN, Singh PP, Bavdekar SB, Sreehari U, Sahni P, Satyanarayana, K, Sharma, Anju, Parikh, Purvish, Vijayan, V K, Sahu, D K, Nayak, Barun K, Gulati, R K, and Parikh, Mahendra N
- Published
- 2008
43. ChemInform Abstract: Confirmation of Structure of Cycloartocarpin from Artocarpus hirsutus.
- Author
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NAIR, A. G. R., VIJAYAN, V. K., and SETHUMADHAVAN, C. V.
- Published
- 1990
- Full Text
- View/download PDF
44. Influenza a virus induced apoptosis: Inhibition of DNA laddering & caspase-3 activity by zinc supplementation in cultured HeLa cells.
- Author
-
Srivastava, Vikram, Rawall, Shweta, Vijayan, V. K., and Khanna, Madhu
- Subjects
- *
ZINC , *INFLUENZA viruses , *HELA cells , *APOPTOSIS , *PHAGOCYTOSIS , *MACROPHAGES , *CELL culture - Abstract
Background & objectives: The pathogenesis of influenza virus infection involves virus replication in epithelial cells of the respiratory tract and the consequent degeneration of infected cells. Influenza virus induces cellular degeneration following infection of cultured cells in vitro, and the cytopathic effect (CPE) occurs principally through apoptotic cell death. This study was undertaken to find out the effect of zinc on influenza virus induced apoptosis in cultured HeLa cells. Methods: The sub-confluent monolayer HeLa cells were used to study the effect of zinc on influenza virus induced apoptosis. The apoptotic markers viz., caspase-3 activity, phagocytic index, morphological changes, and DNA fragmentation were assayed. Results: When HeLa cells were infected with a cell adapted pathogenic strain of influenza A (A/Udorn/ 317/72H3N2) virus, DNA fragmentation was observed in virus infected cells by 24 h post infection and caspase-3 activity was maximum at 4 h post infection after which it reached to plateau. Treatment of cells with 0.1 5mM concentration of zinc till 8 h post infection inhibited DNA fragmentation and also caspase 3 activity was decreased significantly up to 2 h post infection. Interpretation & conclusions: When the infected HeLa cells were incubated with adherent macrophages, efficient phagocytosis occurred and the release of virus into the culture medium was inhibited. These results suggested that inhibitory effect on influenza virus induced apoptotic death of cultured cells can be determined at an early stage of the infection by treatment of zinc. [ABSTRACT FROM AUTHOR]
- Published
- 2009
45. Pulmonary vascular disorders, Progress in respiratory research, vol. 41.
- Author
-
Vijayan, V. K.
- Subjects
- *
PULMONARY circulation disorders , *NONFICTION - Abstract
The article reviews the book "Pulmonary Vascular Disorders: Progress in Respiratory Research" vol. 41, edited by M. Humbert, R. Souza, and G. Simonneau.
- Published
- 2013
46. Global surveillance, prevention and control of chronic respiratory diseases: A comprehensive approach.
- Author
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Vijayan, V. K.
- Subjects
- *
RESPIRATORY diseases , *CHRONIC diseases , *NONFICTION - Abstract
The article reviews the book "Global Surveillance, Prevention and Control of Chronic Respiratory Diseases: A Comprehensive Approach."
- Published
- 2008
47. Principles of Respiratory Medicine.
- Author
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Vijayan, V. K.
- Published
- 2011
48. Role of oxidative stress & transient receptor potential in chronic obstructive pulmonary disease.
- Author
-
Bose, Protiti, Bathri, Rashmi, Kumar, Lalit, Vijayan, V. K., and Maudar, K. K.
- Subjects
- *
OBSTRUCTIVE lung diseases , *OXIDATIVE stress , *TRP channels , *ANTIOXIDANTS , *SENSORY neurons - Abstract
Chronic obstructive pulmonary disease (COPD) affect millions of people worldwide and is known to be one of the leading causes of death. The highly sensitive airways protect themselves from irritants by cough and sneeze which propel endogenous and exogenous substances to minimize airway noxious effects. One noxious effect of these substances is activation of peripheral sensory nerve endings of nociceptor neurons innervating these airways lining thus transmitting dangerous signals from the environment to the central nervous system (CNS). Nociceptor neurons include transient receptor potential (TRP) ion channels, especially the vanilloid and ankyrin subfamilies, TRPV1/A1 which can be activated by noxious chemical challenges in models of airways disease. As oxidative stress may activate airways sensory neurons and contribute to COPD exacerbations we sought to review the role that TRP channel activation by oxidative signals may have on airway responses. it would be prudent to target the TRP channels with antagonists and lower systemic oxidative stress with agents that can modulate TRP expression and boost the endogenous levels of antioxidants for treatment and management of COPD. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
49. Quality of asthma management in an urban community in Delhi, India.
- Author
-
Kotwani, Anita, Chhabra, S. K., Tayal, Vandana, and Vijayan, V. K.
- Subjects
- *
ASTHMA treatment , *PUBLIC health , *SPIROMETRY , *QUALITY of life ,DEVELOPING countries - Abstract
Background & objectives: High prevalence and poor control of asthma make its management a major public health issue worldwide, especially in developing countries. Optimum review of asthma management in the community is essential to improve asthma control. This study was conducted to investigate the quality of asthma management, knowledge about asthma and quality of life of asthma patients referred to a public tertiary care chest hospital in Delhi. Methods: Diagnosis of asthma was confirmed by symptoms and reversible spirometry in 50 referred patients on their first visit. Patients were interviewed using three questionnaires on quality of asthma management before visiting referral hospital, asthma knowledge and asthma quality of life (AQLQ). Correlation amongst quality of treatment, asthma quality of life, and asthma knowledge was also determined. Results: Findings revealed that only 60 per cent of patients were informed about their disease, and 10 per cent had undergone lung function tests previously. Only 44 per cent of patients were prescribed inhalers. None were provided with any educational material. Patients had poor knowledge of aetiology, pathophysiology, medication and how to assess the severity of their asthma. The mean scores in AQLQ indicated a moderate degree of impairment in quality of life. Interpretations & conclusions: This study provides evidence of unsatisfactory asthma management and patient-doctor interaction as patients had limited knowledge of asthma disease, its management and had poor quality of life as measured by a standardized questionnaire. Thus, there is need to implement suitable interventions to improve asthma management according to standard treatment guidelines in the community. [ABSTRACT FROM AUTHOR]
- Published
- 2012
50. Indian Guidelines on Nebulization Therapy.
- Author
-
Katiyar SK, Gaur SN, Solanki RN, Sarangdhar N, Suri JC, Kumar R, Khilnani GC, Chaudhary D, Singla R, Koul PA, Mahashur AA, Ghoshal AG, Behera D, Christopher DJ, Talwar D, Ganguly D, Paramesh H, Gupta KB, Kumar T M, Motiani PD, Shankar PS, Chawla R, Guleria R, Jindal SK, Luhadia SK, Arora VK, Vijayan VK, Faye A, Jindal A, Murar AK, Jaiswal A, M A, Janmeja AK, Prajapat B, Ravindran C, Bhattacharyya D, D'Souza G, Sehgal IS, Samaria JK, Sarma J, Singh L, Sen MK, Bainara MK, Gupta M, Awad NT, Mishra N, Shah NN, Jain N, Mohapatra PR, Mrigpuri P, Tiwari P, Narasimhan R, Kumar RV, Prasad R, Swarnakar R, Chawla RK, Kumar R, Chakrabarti S, Katiyar S, Mittal S, Spalgais S, Saha S, Kant S, Singh VK, Hadda V, Kumar V, Singh V, Chopra V, and B V
- Subjects
- Child, Humans, Aged, Pandemics, Bronchodilator Agents therapeutic use, Health Personnel, COVID-19, Pulmonary Disease, Chronic Obstructive drug therapy
- Abstract
Inhalational therapy, today, happens to be the mainstay of treatment in obstructive airway diseases (OADs), such as asthma, chronic obstructive pulmonary disease (COPD), and is also in the present, used in a variety of other pulmonary and even non-pulmonary disorders. Hand-held inhalation devices may often be difficult to use, particularly for children, elderly, debilitated or distressed patients. Nebulization therapy emerges as a good option in these cases besides being useful in the home care, emergency room and critical care settings. With so many advancements taking place in nebulizer technology; availability of a plethora of drug formulations for its use, and the widening scope of this therapy; medical practitioners, respiratory therapists, and other health care personnel face the challenge of choosing appropriate inhalation devices and drug formulations, besides their rational application and use in different clinical situations. Adequate maintenance of nebulizer equipment including their disinfection and storage are the other relevant issues requiring guidance. Injudicious and improper use of nebulizers and their poor maintenance can sometimes lead to serious health hazards, nosocomial infections, transmission of infection, and other adverse outcomes. Thus, it is imperative to have a proper national guideline on nebulization practices to bridge the knowledge gaps amongst various health care personnel involved in this practice. It will also serve as an educational and scientific resource for healthcare professionals, as well as promote future research by identifying neglected and ignored areas in this field. Such comprehensive guidelines on this subject have not been available in the country and the only available proper international guidelines were released in 1997 which have not been updated for a noticeably long period of over two decades, though many changes and advancements have taken place in this technology in the recent past. Much of nebulization practices in the present may not be evidence-based and even some of these, the way they are currently used, may be ineffective or even harmful. Recognizing the knowledge deficit and paucity of guidelines on the usage of nebulizers in various settings such as inpatient, out-patient, emergency room, critical care, and domiciliary use in India in a wide variety of indications to standardize nebulization practices and to address many other related issues; National College of Chest Physicians (India), commissioned a National task force consisting of eminent experts in the field of Pulmonary Medicine from different backgrounds and different parts of the country to review the available evidence from the medical literature on the scientific principles and clinical practices of nebulization therapy and to formulate evidence-based guidelines on it. The guideline is based on all possible literature that could be explored with the best available evidence and incorporating expert opinions. To support the guideline with high-quality evidence, a systematic search of the electronic databases was performed to identify the relevant studies, position papers, consensus reports, and recommendations published. Rating of the level of the quality of evidence and the strength of recommendation was done using the GRADE system. Six topics were identified, each given to one group of experts comprising of advisors, chairpersons, convenor and members, and such six groups (A-F) were formed and the consensus recommendations of each group was included as a section in the guidelines (Sections I to VI). The topics included were: A. Introduction, basic principles and technical aspects of nebulization, types of equipment, their choice, use, and maintenance B. Nebulization therapy in obstructive airway diseases C. Nebulization therapy in the intensive care unit D. Use of various drugs (other than bronchodilators and inhaled corticosteroids) by nebulized route and miscellaneous uses of nebulization therapy E. Domiciliary/Home/Maintenance nebulization therapy; public & health care workers education, and F. Nebulization therapy in COVID-19 pandemic and in patients of other contagious viral respiratory infections (included later considering the crisis created due to COVID-19 pandemic). Various issues in different sections have been discussed in the form of questions, followed by point-wise evidence statements based on the existing knowledge, and recommendations have been formulated., Competing Interests: Conflicts of interest The authors have none to declare., (Copyright © 2022 Tuberculosis Association of India. Published by Elsevier B.V. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
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