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Your search keyword '"Verdoux, Helene"' showing total 116 results
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116 results on '"Verdoux, Helene"'

4. Exploring low clozapine C/D ratios, inverted clozapine-norclozapine ratios and undetectable concentrations as measures of non-adherence in clozapine patients: A literature review and a case series of 17 patients from 3 studies

Author

Ruan, Can-Jun, Olmos, Ismael, Ricciardi, Carina, Schoretsanitis, Georgios, Vincent, Philippe D., Anıl Yağcıoğlu, A. Elif, Eap, Chin B., Baptista, Trino, Clark, Scott R., Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Every-Palmer, Susanna, Procyshyn, Ric M., Rohde, Christopher, Suhas, Satish, Schulte, Peter F.J., Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U., Molden, Espen, De Las Cuevas, Carlos, and de Leon, Jose

Published
2024
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5. Clozapine ultrarapid metabolism during weak induction probably exists but requires careful diagnosis. A literature review, five new cases and a proposed definition

Author

Schoretsanitis, Georgios, Anıl Yağcıoğlu, A. Elif, Ruan, Can-Jun, Eap, Chin B., Molden, Espen, Baptista, Trino, Clark, Scott R., Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Olmos, Ismael, Every-Palmer, Susanna, Procyshyn, Ric M., Rohde, Christopher, Satish, Suhas, Schulte, Peter F.J., Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U., and de Leon, Jose

Published
2024
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14. International trends in antipsychotic use: A study in 16 countries, 2005–2014

Author

Hálfdánarson, Óskar, Zoëga, Helga, Aagaard, Lise, Bernardo, Miquel, Brandt, Lena, Fusté, Anna Coma, Furu, Kari, Garuoliené, Kristina, Hoffmann, Falk, Huybrechts, Krista F., Kalverdijk, Luuk J., Kawakami, Koji, Kieler, Helle, Kinoshita, Takuya, Litchfield, Melisa, López, Soffy C., Machado-Alba, Jorge E., Machado-Duque, Manuel E., Mahesri, Mufaddal, Nishtala, Prasad S., Pearson, Sallie-Anne, Reutfors, Johan, Saastamoinen, Leena K., Sato, Izumi, Schuiling-Veninga, Catharina C.M., Shyu, Yu-Chiau, Skurtveit, Svetlana, Verdoux, Hélène, Wang, Liang-Jen, Yahni, Corinne Zara, and Bachmann, Christian J.

Published
2017
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18. Specific vs general cognitive remediation for executive functioning in schizophrenia: A multicenter randomized trial

Author

Franck, Nicolas, Duboc, Chloé, Sundby, Charlotte, Amado, Isabelle, Wykes, Til, Demily, Caroline, Launay, Corinne, Le Roy, Vincent, Bloch, Pascal, Willard, Dominique, Todd, Aurélia, Petitjean, François, Foullu, Sandrine, Briant, Patrick, Grillon, Marie-Laure, Deppen, Patricia, Verdoux, Hélène, Bralet, Marie-Cécile, Januel, Dominique, Riche, Benjamin, Roy, Pascal, and Vianin, Pascal

Published
2013
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27. J Psychiatry Neurosci

Author

SISKIND, D., HONER, W. G., Clark, S., CORRELL, C. U., Hasan, A., HOWES, O., KANE, J. M., KELLY, D. L., LAITMAN, R., Lee, J., MACCABE, J. H., MYLES, N., Nielsen, J., SCHULTE, P. F., Taylor, D., VERDOUX, Helene, Wheeler, A., FREUDENREICH, O., Bordeaux population health (BPH), and Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
PharmacoEpi-Drugs, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Published
2020

28. Life-threatening adverse drug reactions at admission to medical intensive care: a prospective study in a teaching hospital

Author

Grenouillet-Delacre, Marieke, Verdoux, Helene, Moore, Nicholas, Haramburu, Francoise, Miremont-Salame, Ghada, Etienne, Gabriel, Robinson, Philip, Gruson, Didier, Hilbert, Gilles, Gabinski, Claude, Begaud, Bernard, and Molimard, Mathieu

Subjects
Drugs -- Health aspects -- Research, Hospital patients -- Health aspects -- Research, Health care industry
Abstract

Objective: To assess the characteristics of life-threatening adverse drug reactions in patients admitted to medical intensive care unit and to define those that could facilitate early identification. Design: A prospective 6-month observational study. Patients: Of the 436 admissions to the teaching hospital medical intensive care unit, all patients aged over 15 years and who had received documented drug treatment were included (n = 405). Measurements: Characteristics of patients [age, gender, underlying diseases, organ failure(s), drugs taken, Severity Acute Physiologic Score II, length of stay, outcome at discharge] were prospectively collected using a standardised questionnaire. A panel of experts assessed putative serious adverse drug reaction(s) for each drug taken and each organ failure at admission by using a standardised causality assessment method. Characteristics of patients with and without serious adverse drug reactions at admission were compared using univariate and then stepwise descending multivariate logistic regression. Results: Of the 405 patients included, 111 (27.4%) presented an adverse drug reaction leading to organ failure. In 48% of cases adverse drug reactions were preventable, 23% were undiagnosed and 19% contributed to death. Age over 75 years [odds ratio (OR) 2.25; 95% confidence interval (CI) 1.15-4.38; p = 0.02], having more than three drugs (OR 6.90; 95% CI 1.44-33.00; p = 0.02) and a diagnosis of haematological malignancy (OR 6.19; 95% CI 2.07-18.53; p = 0.001) were independently associated with serious adverse drug reactions. Conclusions: Preventable life-threatening adverse drug reactions were frequently involved in organ failure at admission to medical intensive care; many of them had not been identified. Keywords Serious adverse drug reaction * Organ failure * Intensive care unit, Introduction Adverse drug reactions (ADRs) are frequent and can occur during hospitalisation leading to either hospitalisation or prolongation of stay [1, 2]. Serious ADRs are fatal in 5% of cases, [...]

Published
2007
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37. Psychiatry Res

Author

VERDOUX, Helene, QUILES, C., CERVELLO, S., DUBREUCQ, J., BON, L., MASSOUBRE, C., POMMIER, R., LEGROS-LAFARGE, E., JAAFARI, N., GUILLARD-BOUHET, N., CHEREAU-BOUDET, I., COUHET, G., PLASSE, J., and FRANCK, N.

Published
2019

38. Schizophr Res

Author

VERDOUX, Helene, QUILES, C., and DE LEON, J.

Published
2019

47. Psychotic Experiences and Related Distress: A Cross-national Comparison and Network Analysis Based on 7141 Participants From 13 Countries

Author

WUSTEN, C., SCHLIER, B., JAYA, E. S., GENETIC, Risk, FONSECA-PEDRERO, E., Peters, E., VERDOUX, Helene, WOODWARD, T. S., ZIERMANS, T. B., LINCOLN, T. M., Bordeaux population health (BPH), and Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
body regions, PharmacoEpi-Drugs, endocrine system, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, human activities
Abstract

Psychotic experiences (PEs) are common in the general population but do not necessarily reflect a risk status if they occur in relative isolation or are not distressing. Emerging evidence suggests that PEs might be experienced as more benign for individuals from collectivistic low- and middle-income countries (LAMIC) compared with individualistic high-income countries (HIC). The aim of this study was to determine whether: (1) self-reported PEs are less distressing in community samples from LAMIC than from HIC; (2) the network of PEs is significantly less connected in a sample from LAMIC than from HIC. Adults from 8 HIC (n = 4669) and 5 LAMIC (n = 2472) were compared. The lifetime frequency of PEs and related distress were assessed with the Community Assessment of Psychic Experiences. We analyzed the associations of PEs with distress and country type. The interconnection of PEs was visualized by a network analysis and tested for differences in global connection strengths. The average endorsement rates of PEs were significantly higher in LAMIC than in HIC (chi2 = 1772.87, P < .01, Phicramer = 0.50). There was a universal positive correlation between higher frequency of PEs and more distress, but the distress levels controlled for frequency were significantly higher in HIC (R2 = 0.11; b = 0.26; SE = 0.01; T = 17.68; P < .001). Moreover, the network of PEs was significantly less connected in LAMIC (S = 0.40, P < .05). The findings indicate that PEs are of less clinical relevance in LAMIC compared with HIC. The universal use of current high-risk criteria might thus not be adequate without consideration of associated distress and cultural values.

Published
2018

48. Antidepressants and Hepatotoxicity: A Cohort Study among 5 Million Individuals Registered in the French National Health Insurance Database

Author

Billioti de Gage, Sophie, Collin, C., Le-Tri, T., Pariente, Antoine, Begaud, Bernard, Verdoux, Helene, Dray-Spira, R., Zureik, M., Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Agence nationale de sécurité du médicament et des produits de santé [Saint-Denis] (ANSM), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), and Admin, Oskar

Subjects
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology
Abstract

International audience; BACKGROUND: Hepatotoxicity may be a concern when prescribing antidepressants. Nevertheless, this risk remains poorly understood for serotonin and noradrenaline reuptake inhibitors (SNRIs: venlafaxine, milnacipran, duloxetine) and 'other antidepressants' (mianserin, mirtazapine, tianeptine and agomelatine), particularly in comparison with selective serotonin reuptake inhibitors (SSRIs: fluoxetine, citalopram, paroxetine, sertraline, fluvoxamine, escitalopram), which are by far the most commonly prescribed antidepressants.OBJECTIVE: We quantified the risk of serious liver injury associated with new use of SNRIs and 'other antidepressants' compared with SSRIs in real-life practice.METHODS: Based on the French national health insurance database, this cohort study included 4,966,825 individuals aged 25 years and older with a first reimbursement of SSRIs, SNRIs or 'other antidepressants' between January 2010 and June 2015. We compared the risk of serious liver injury within the 6 months following antidepressant initiation according to antidepressant class, with SSRIs as the reference, using an inverse probability-of-treatment-weighted Cox proportional hazard model adjusted for demographic characteristics and risk factors of liver injury. RESULTS: We identified 382 serious liver injuries overall (none for milnacipran initiators). Age and gender standardized incidence rates per 100,000 person-years were 19.2 for SSRIs, 22.2 for venlafaxine, 12.6 for duloxetine, 21.5 for mianserin, 32.8 for mirtazapine, 31.6 for tianeptine and 24.6 for agomelatine initiators. Initiation of antidepressants of interest versus SSRIs was not associated with an increased risk of serious liver injury [adjusted hazard ratios (95% confidence interval): venlafaxine 1.17 (0.83-1.64), duloxetine 0.54 (0.28-1.02), mianserin 0.90 (0.58-1.41), mirtazapine 1.17 (0.67-2.02), tianeptine 1.35 (0.82-2.23) and agomelatine 1.07 (0.51-2.23)]. This finding was confirmed by the results of an additional study using a case-time-control design.CONCLUSION: These results do not provide evidence of an increased risk of serious liver injury following initiation of SNRIs or 'other antidepressants' compared with SSRIs in real-life practice. This could reflect an inherent lack of difference in risk between the drug classes, or the fact that individuals with higher susceptibility to drug-induced liver injury are not prescribed drugs considered to be more hepatotoxic.

Published
2018

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