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1. IVIg-induced headache: prospective study of a large cohort with neurological disorders

Author

Hasırcı Bayır, Buse Rahime, Ünsal, Miraç Ayşen, Ağırcan, Cansu, Cerrahoğlu Şirin, Tuba, Akan, Onur, Gürsoy, Gizem, Eyigürbüz, Tuğba, Mermi Dibek, Dilara, Akdağ, Gönül, Elmalı, Ayşe Deniz, Nazlı, Ezgi, Akkoyun Arıkan, Fatma, Alpaydın Baslo, Sezin, Ağırcan, Dilek, Oguz-Akarsu, Emel, Ertürk Çetin, Özdem, Gesoğlu Demir, Tülin, Acıman Demirel, Esra, Vurallı, Doğa, Deveci, Şule, Tanyel, Tuba, Mayda Domaç, Füsun, Karlı, Necdet, Velioğlu, Sibel, and Baykan, Betül

Published
2023
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2. Exploring shared triggers and potential etiopathogenesis between migraine and idiopathic/genetic epilepsy: Insights from a multicenter tertiary-based study

Author

Yapıcı, Zuhal, Midi, İpek, Saygı, Serap, Çelebi, Ulufer, Darol, Elif Sarıca, Ağan, Kadriye, Ayça, Senem, Gazioğlu, Sibel, Okudan, Zeynep Vildan, Şirin, Nermin Görkem, Bebek, Nerses, Dericioğlu, Neşe, Altun, İlknur Güçlü, Yalçın, Ayşe Destina, Sürmeli, Reyhan, Erdinç, Oğuz Osman, Erdal, Abidin, Algın, Demet İlhan, Kutlu, Gülnihal, Bek, Semai, Erdal, Yüksel, Özön, Akçay Övünç, Reyhani, Aylin, Güldiken, Babürhan, Baklan, Barış, Genç, Bülent Oğuz, Altındağ, Ebru Aykutlu, Karahan, Gökçen, Koç, Güray, Mısırlı, Handan, Öztura, İbrahim, Aslan-Kara, Kezban, Çakar, Merve Melodi, Türkmen, Nur, Bulut, Onur, Karadaş, Ömer, Şahin, Özlem Kesim, Ferik, Sevgi, Peköz, Mehmet Taylan, Topaloğlu, Pınar, Özek, Sibel Üstün, Düzgün, Ülkühan, Yayla, Vildan, Gömceli, Yasemin, Acar, Zeynep Ünlüsoy, Türk, Bengi Gül, Yeni, Seher Naz, Atalar, Arife Çimen, Ekizoğlu, Esme, Gök, Duygu Kurt, Baykan, Betül, Özge, Aynur, Ayta, Semih, Erdoğan, Füsun Ferda, Taşdelen, Bahar, and Velioğlu, Sibel K.

Published
2024
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3. The effect of sleep disorders on quality of life in patients with epilepsy: A multicenter study from Turkey

Author

Akdağ, Gönül, Canbaz Kabay, Sibel, Bican Demir, Aylin, Ergin Bakar, Ebru, Koç, Güray, Üstün Özek, Sibel, Küçük, Ahmet, Ünsal, Miraç Ayşen, Neyal, Abdurrahman, Florentina Ateş, Miruna, Çelik, Havva Tuğba, Kılıçparlar Cengiz, Emine, Kutlu, Gülnihal, Ağırcan, Dilek, Karacan Gölen, Meltem, Bek, Semai, Çınar, Nilgün, Sahin, Sevki, Şişman Bayar, Aysel Büşra, Terzi, Murat, Kendirli Aslan, Sude, Kenar, Safiye Gül, Kutluhan, Süleyman, Ekmekyapar Fırat, Yasemin, Yılmaz Okuyan, Dilek, Bayar, Muhammet Duran, Mert Atmaca, Murat, Yalçın, Destina, Genç, Fatma, Köse Leba, Leyla, Yılmaz, Buket, Eren, Fettah, Bolu, Naci Emre, Keskin Güler, Selda, Akıncı, Tuba, Reyhani, Aylin, Yıldırım Sitembölükbaşı, Neslişah, Türkmen, Nur, Karşıdağ, Sibel, Velioğlu, Sibel K., Demir, Ayşegül, Haytı, Barış, Hasırcı Bayır, Buse Rahime, Ezgi Uçan Tokuç, Firdevs, Demir, Göksemin, Çakmakçı, Güngör, Özkan, Hülya, Bulut, Onur, Kesim Şahin, Özlem, Sürmeli, Reyhan, Tekin, Selma, Sarıoğlu, Şerife Gizem, Gesoğlu Demir, Tülin, Akkoyun Arıkan, Fatma, and Çetiner, Mustafa

Published
2024
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4. Global uncertainty in the diagnosis of neurological complications of SARS-CoV-2 infection by both neurologists and non-neurologists: An international inter-observer variability study

Author

Abbariao, Maritoni, Zaki, Shafiq Dexter Abou, Aleksic, Dejan, Aliling, Nicole, Rivas, Susana Arias, Artajos, Godard, Asukile, Melody, Atalar, Arife Çimen, Bae, Jong Seok, Banzrai, Chimeglkham, Bar, Michal, Barone, Valentina, Baykan, Betul, Beghi, Ettore, Berger, Thomas, Bilic, Ivica, Biller, Jose, Boskovic, Mateja, Cabreira, Verónica, Calado, Sofia, Canete, Maria Teresa, Celebisoy, Nese, Chen, Ike Leon, Chishimba, Lorraine, Chomba, Mashina, Constantino, Glenn Anthony, Cotelli, Maria Sofia, De Cauwer, Harald, Debroucker, Thomas, Orantes, Luis Del Carpio, Devaraj, Rashmi, D'Souza, Michelle, Ekizoglu, Esme, Elmali, Ayse Deniz, Fonseca, Ana Catarina, Furloni, Roberto, Gajre, Sunil, Azorin, David Garcia, Garfoot, Vanessa, Gasparic, Irena, Genç, Hamit, Glavica, Marinka, Guanaes, Luiz Gustavo, Gürsoy, Gizem, Hafiz, Nauman, Hasırcı, Buse, Helbok, Raimund, Hor, Chee Peng, Hughes, Stella, Hwang, Sungeun, Kaya, Irem Ilgezdi, Jakupi, Adi, Jamora, Roland Dominic, Kahwagi, Jamil, Kaprelyan, Ara, Kawatu, Nfwama, Kim, Manho, Kim, Hyunji, Kim, Hyun Kyung, Koffie, Desmond, Ladeira, Filipa, Lant, Suzannah, Lee, Woo-Jin, Lee, Sukyoon, Leonardo, Zerlyn, Lim, Christian Emmanuel, Lisak, Marijana, Loh, Hong Chuan, Loo, Lay Khoon, Huzjan, Arijana Lovrencic, Koh, Rosie Sue Luan Lu, Luabeya, Mesu'a Kabwa, Lugaresi, Alessandra, Macrohon, Bernadette, Majdak, Maja, Manalili, Sheryl, Manelli, Filippo, Mapoure, Yacouba Njankouo, Mascarella, Davide, Massano, João, Mataa, Mataa, Matibag, Jessica Leika, Matic-Gerodias, Alexandria, McMullen, Kate, Miranda, Miguel, Modequillo, Margaret, Shoab, Abul Kalam Mohammed, Motto, Cristina, Murphy, Sinead M., Mwendaweli, Naluca, Ng, Chen Fei, Ng, Rong Xiang, Ihsan, Mohd Khairul Nizam Nor, Nyein, Aye Myat, O'Connell, Karen, Oh, Seong-il, Ohnmar, Ohnmar, Özge, Aynur, Pajo, Azalea, Palavra, Filipe, Panteleienko, Larysa, Payne, Catherine, Pensato, Umberto, Peres, João, Peters, Steven, Polat, Burcu, Poljakovic, Zdravka, Punter, Martin Nicholas Michael, Quiles, Liz Edenberg, Ranieri, Angelo, Ratković, Marija, Renales, Maria Lina, Robles, Jose, Bedeković, Marina Roje, Rommer, Paulus, Šapina, Lidija, Sarac, Helena, Saylor, Deanna, Schmutzhard, Erich, Sharma, Anahita, Šimić, Aleksandra, Sipilä, Jussi O.T., Sokhi, Dilraj, Stagno, Mauro, Stancheva, Kristina, Stojsavljević, Marija, Subir, Ahamed, Surdhar, Sushee, Talabucon, Loreto, Jr, Tan, Hui Jan, Teoh, Sing Chiek, Vallejo, Dionis, Velioglu, Sibel K., Vukasović, Rafaela, Kit, Wong Wai, Welte, Tamara, Willekens, Barbara, Yesilot, Nilufer, Yu, Jeryl Ritzi T., Zaw, Moe Moe, Zhelyazkova, Sashka, Žitnik, Eva, Tamborska, A.A., Wood, G.K., Westenberg, E., Garcia-Azorin, D., Webb, G., Schiess, N., Netravathi, M., Baykan, B., Dervaj, R., Helbok, R., Lant, S., Özge, A., Padovani, A., Saylor, D., Schmutzhard, E., Easton, A., Lilleker, J.B., Jackson, T., Beghi, E., Ellul, M.A., Frontera, J.A., Pollak, T., Nicholson, T.R., Wood, N., Thakur, K.T., Solomon, T., Stark, R.J., Winkler, A.S., and Michael, B.D.

Published
2023
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5. Peri-ictal headache: An underestimated prognostic finding associated with idiopathic epilepsies

Author

Yapıcı, Zuhal, Midi, İpek, Saygı, Serap, Çelebi, Ulufer, Sarıca Darol, Elif, Ağan, Kadriye, Ayça, Senem, Gazioğlu, Sibel, Vildan Okudan, Zeynep, Görkem Şirin, Nermin, Bebek, Nerses, Dericioğlu, Neşe, Güçlü Altun, İlknur, Destina Yalçın, Ayşe, Sürmeli, Reyhan, Osman Erdinç, Oğuz, Erdal, Abidin, İlhan Algın, Demet, Kutlu, Gülnihal, Bek, Semai, Erdal, Yüksel, Övünç Özön, Akçay, Reyhani, Aylin, Güldiken, Babürhan, Baklan, Barış, Oğuz Genç, Bülent, Aykutlu Altındağ, Ebru, Karahan, Gökçen, Koç, Güray, Mısırlı, Handan, Öztura, İbrahim, Aslan-Kara, Kezban, Melodi Çakar, Merve, Türkmen, Nur, Bulut, Onur, Karadaş, Ömer, Kesim Şahin, Özlem, Ferik, Sevgi, Taylan Peköz, Mehmet, Üstün Özek, Sibel, Düzgün, Ülkühan, Yayla, Vildan, Gömceli, Yasemin, Ünlüsoy Acar, Zeynep, Ekizoglu, Esme, Baykan, Betül, Çimen Atalar, Arife, Gül Türk, Bengi, Kurt Gök, Duygu, Topaloglu, Pınar, Özge, Aynur, Ayta, Semih, Ferda Erdoğan, Füsun, Naz Yeni, Seher, Taşdelen, Bahar, and Velioğlu, Sibel K.

Published
2023
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9. Diagnosis of comorbid migraine without aura in patients with idiopathic/genetic epilepsy based on the gray zone approach to the International Classification of Headache Disorders 3 criteria

Author

Atalar, Arife Çimen, Özge, Aynur, Türk, Bengi Gül, Ekizoğlu, Esme, Kurt Gök, Duygu, Baykan, Betül, Ayta, Semih, Erdoğan, Füsun Ferda, Yeni, Seher Naz, Taşdelen, Bahar, and Velioğlu, Sibel K.

Subjects
Neurology, Neurology (clinical)
Abstract

BackgroundMigraine without aura (MwoA) is a very frequent and remarkable comorbidity in patients with idiopathic/genetic epilepsy (I/GE). Frequently in clinical practice, diagnosis of MwoA may be challenging despite the guidance of current diagnostic criteria of the International Classification of Headache Disorders 3 (ICHD-3). In this study, we aimed to disclose the diagnostic gaps in the diagnosis of comorbid MwoA, using a zone concept, in patients with I/GEs with headaches who were diagnosed by an experienced headache expert.MethodsIn this multicenter study including 809 consecutive patients with a diagnosis of I/GE with or without headache, 163 patients who were diagnosed by an experienced headache expert as having a comorbid MwoA were reevaluated. Eligible patients were divided into three subgroups, namely, full diagnosis, zone I, and zone II according to their status of fulfilling the ICHD-3 criteria. A Classification and Regression Tree (CART) analysis was performed to bring out the meaningful predictors when evaluating patients with I/GEs for MwoA comorbidity, using the variables that were significant in the univariate analysis.ResultsLonger headache duration (n = 62) in the CART analysis were 48.39% Juvenile myoclonic epilepsy followed by 25.81% epilepsy with generalized tonic-clonic seizures alone.ConclusionLonger headache duration, throbbing pain, increase of pain by physical activity, photophobia and/or phonophobia, presence of vertigo/dizziness, osmophobia, and higher VAS scores are the main supportive associated factors when applying the ICHD-3 criteria for the comorbid MwoA diagnosis in patients with I/GEs. Evaluating these characteristics could be helpful to close the diagnostic gaps in everyday clinical practice and fasten the diagnostic process of comorbid MwoA in patients with I/GEs.

Published
2023
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10. IVIg-induced headache: prospective study of a large cohort with neurological disorders

Author

Eyigürbüz, Tuğba, Alpaydın Baslo, Sezin, Akkoyun Arıkan, Fatma, Nazlı, Ezgi, Elmalı, Ayşe Deniz, Akdağ, Gönül, Mermi Dibek, Dilara, Okudan Atay, Zeynep Vildan, Gürsoy, Gizem, Akan, Onur, Ertürk Çetin, Özdem, Oguz-Akarsu, Emel, Ağırcan, Dilek, Cerrahoğlu Şirin, Tuba, AĞIRCAN, CANSU, Ünsal, Miraç Ayşen, Hasırcı Bayır, Buse Rahime, Bekdik, Pınar, Mutluay, Belgin Munise, Karagöz Sakallı, Nazan, Öksüz, Nevra, İlgen Uslu, Ferda, Çulha Oktar, Ayla, Baykan, Betül, Velioğlu, Sibel, Karlı, Necdet, Mayda Domaç, Füsun, Tanyel, Tuba, Deveci, Şule, Vurallı, Doğa, Acıman Demirel, Esra, and Gesoğlu Demir, Tülin

Abstract

Background: Intravenous immune globulin (IVIg) is frequently used in some neurological diseases and is also the first-line therapy in Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy. We aimed to evaluate the frequency and characteristics of headaches, which is one of the most common side effects of IVIg treatment. Methods: Patients who received IVIg treatment for neurological diseases were prospectively enrolled in 23 centers. Firstly, the characteristics of patients with and without IVIg-induced headaches were analyzed statistically. Then, patients with IVIg-induced headaches were classified into three subgroups determined by their history: no primary headache, tension-type headache (TTH), and migraine. Results: A total of 464 patients (214 women) and 1548 IVIg infusions were enrolled between January and August 2022. The frequency of IVIg-related headaches was 27.37% (127/464). A binary logistic regression analysis performed with significant clinical features disclosed that female sex and fatigue as a side effect were statistically more common in the IVIg-induced headache group. IVIg-related headache duration was long and affected daily living activities more in patients with migraine compared to no primary headache and TTH groups (p = 0.01, respectively). Conclusion: Headache is more likely to occur in female patients receiving IVIg and those who develop fatigue as a side effect during the infusion. Clinicians’ awareness of IVIg-related headache characteristics, especially in patients with migraine, may increase treatment compliance.

Published
2023

11. One Patient, Three Providers: A Multidisciplinary Approach to Managing Common Neuropsychiatric Cases.

Author

Özge, Aynur, Domaç, Füsun Mayda, Tekin, Nil, Sünbül, Esra Aydın, Öksüz, Nevra, Atalar, Arife Çimen, Çallı, Sümeyye Yasemin, Fidan, Yağmur Sever, Evlice, Ahmet, Beştepe, Engin Emrem, İzci, Filiz, Küsbeci, Özge Yılmaz, Demirel, Esra Acıman, Velioğlu, Sibel K., and Ungan, Mehmet

Subjects
MEDICAL personnel, AFFECTIVE disorders, PHYSICIANS' attitudes, BIPOLAR disorder, MEDICATION abuse, POSTHERPETIC neuralgia, EPILEPSY
Abstract

Background: Neuropsychiatric cases require a multidisciplinary approach for effective management. This paper presented case-based discussions on migraine, dementia, epilepsy, mood disorders, neuralgia, and psychosis from the perspectives of a family physician, neurologist, and psychiatrist. The goal was to highlight the importance of collaboration between healthcare providers in managing these complex cases. Methods: The paper was based on the proceedings of the Mediterranean Neuropsychiatry Symposium, where experts from family medicine, neurology, and psychiatry came together for comprehensive case-based discussions. The CARE framework (Case Report, Appraisal, Research, and Education) was developed to guide reporting and evaluation of case reports in clinical practice. Results: Six cases were presented and discussed, highlighting the importance of a multidisciplinary approach in managing neuropsychiatric cases. The cases included chronic migraine with medication overuse, memory dysfunction with language and behavioral problems, refractory epileptic seizures with subjective sensory symptoms, bipolar affective disorder with normal pressure hydrocephalus, postherpetic neuralgia in a case with bipolar affective disorder, and psychosis with recurrent attacks with the abuse of several substances. Conclusion: A biopsychosocial multidisciplinary approach is essential for managing neuropsychiatric cases effectively on behalf of the patients and public health of the country. The CARE framework can guide the reporting and evaluation of case reports in clinical practice, ensuring that patients receive comprehensive and effective care. Healthcare providers should collaborate to provide the best possible care for patients with complex and multifaceted needs. [ABSTRACT FROM AUTHOR]

Published
2023
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12. The Prevalence Of Migraine Comorbidity In Idiopathic Epilepsy Syndromes: The Preliminary Results Of A Multıcenter Study Across Turkey

Author

BEBEK, NERSES, YAPICI, Zuhal, SARICA VAROL, ELİF, Yalcin, Ayse Destina, SÜRMELİ, REYHAN, AĞAN YILDIRIM, KADRİYE, GÜÇLÜ ALTUN, İLKNUR, BAKLAN, BARIŞ, BULUT, ONUR, MİDİ, İPEK, GAZİOĞLU, SİBEL, ŞİRİN İNAN, NERMİN GÖRKEM, YAYLA, VİLDAN AYŞE, OKUDAN, ZEYNEP VİLDAN, ATALAR, ARİFE ÇİMEN, TÜRK, BENGİ GÜL, KURT GÖK, DUYGU, EKİZOĞLU TURGUT, ESME, BAYKAN, BETÜL, ÖZGE, AYNUR, AYTA, SEMİH, ERDOĞAN, FİSUN FERDA, YENİ, SEHER NAZ, VELİOĞLU, SİBEL K, ÖZTURA, İBRAHİM, TÜRKMEN, NUR, ÇAKAR, MERVE MELODİ, PEKÖZ, MEHMET TAYLAN, KARAHAN, GÖKÇEN, AYKUTLU ALTINDAĞ, EBRU, ERDİNÇ, OĞUZ OSMAN, ÇELEBİ, ULUFER, ÜSTÜN ÖZEK, SİBEL, and AYÇA, SENEM

Published
2020

19. Congenital Bilateral Perisylvian Syndrome: A Case Report.

Author

GAZİOĞLU, Sibel, ALTUNAYOĞLU ÇAKMAK, Vildan, EYÜBOĞLU, İlker, AKPINAR, Ramazan, and VELİOĞLU, Sibel

Subjects
HUMAN abnormalities, EPILEPSY, PSEUDOBULBAR paralysis, COGNITION disorders, MAGNETIC resonance imaging of the brain, DIAZEPAM, CARBAMAZEPINE
Abstract

Copyright of Epilepsi: Journal of the Turkish Epilepsi Society is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2014
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20. Comparison of Psychiatric Features Between Conversion Disorder and Female Epilepsy Patients with Non-Intractable Seizure.

Author

ÖZKORUMAK, Evrim, GAZİOĞLU, Sibel, TİRYAKİ, Ahmet, VELİOĞLU, Sibel K., and KIZILAY, Pınar

Subjects
PEOPLE with epilepsy, WOMEN patients, CONVERSION disorder, OUTPATIENT medical care, CARE of people, PEOPLE with mental illness, PSYCHIATRIC clinics
Abstract

Copyright of Epilepsi: Journal of the Turkish Epilepsi Society is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2014
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22. Spectrum of hyperexcitability of the brain: migraine and pain sensitivity in epilepsy.

Author

Velioğlu, Sibel K.

Subjects
*EPILEPSY, *EPILEPSY in animals, *PAIN threshold, *MIGRAINE, *MIGRAINE aura, *LABORATORY animals, *COMORBIDITY, *ANIMAL models in research
Abstract

The process that provoke spontaneous seizures that characterizes epilepsy is related to a decrease in the threshold of excitability of neurons. The pathophysiological mechanisms that drive neurons to generate abnormal excessive electrical discharges are still not clearly understood. These neurons, which are silent/calm in the interictal period, are different from normal neurons in many aspects. The conditions that are commonly comorbid with epilepsies, are headaches and painful syndromes. Scientific research on this comorbidity is only limited to clinical studies and has not yet reached results that will clarify the neurobiology of the association. Implementing animal models that have both the disease and the comorbidity and preclinical studies to be performed on them are difficult as methodology, and there is no such study yet. In recent years, two preclinical studies we conducted in experimental animals with genetic epilepsy showed that the pain threshold is reduced in genetic absence epilepsy. Future studies on pain comorbidity in epilepsy will shed a light on the neurobiology of both epilepsy and pain. In this presentation, the neurobiology of epilepsy will be discussed in terms of comorbidity of epilepsy-migraine, and the pain threshold studies in rats with genetic absence epilepsy. [ABSTRACT FROM AUTHOR]

Published
2020

23. Measure of the container officers' daily MET, sleep duration and efficiency via metabolic holter.

Author

Yılmaz, Hatice, Başar, Ersan, Ayar, Ahmet, and Velioğlu, Sibel K.

Subjects
ENERGY consumption, WORK environment, METABOLISM
Abstract

Objective: This study was conducted to determine energy consumption, sleep durations and sleep efficiency in the work environment of 2nd and 3rd officers on container vessels. Methods: A body tracking monitor which is a multi-sensor wearable technology product was used. It is an armband that provides information about energy consumption, lying and sleeping periods and (MET) metabolic severity of physical activities (BSA: Bodymedia Sensewear Armband Pro3).The study was carried out on the container vessels running between Turkish, Mediterranean and Black Sea ports. A total of 127 daily records were obtained from 8 healthy male volunteers (mean age 25.8, mean BMI 23.8 kg/m2) with BSA. Bodymedia SenseWearPro 6.1 software algorithms were used in the evaluation of data. Results: The 2nd officers were responsible for shifts from 00.00-04.00/12.00-16.00 or 00.00-06.00/12.00-18.00, while the 3rd officers from 08.00-12.00/20.00-00.00 or 06.00-12.00/ 18.00-00.00. 2nd officers' average energy consumption was 3.114 kcal/day (SD±570), daily MET value was 1.6 (SD±0.2). That was 3.523 kcal (SD±762) and 2.0 (SD±0.3) for the 3rd officers'. The average energy consumption of all was 3.320 kcal/day (SD±702); daily MET was 1.8 (SD±0.3); lying time was 7.2 hours/day (SD±2.0); sleeping time was 4.7 hours/day (SD±1.4); sleep efficiency was 66.1% (SD±14.2). A difference was not found between the 2nd and 3rd officers' average lying, sleeping times and efficiency. However, there was a correlation of -0.55 between MET and sleep duration in the 3rd officers,and this value was -0.25 in the 2nd officers. Conclusion: The watchkeeping officers on container vessels in shortsea shipping, are not able to sleep in sufficient efficiency and time.The officers consume more energy and sleep less.This is seen as dangerous for workers and their environment in a ship atmosphere with various risks. It does not coincide with the aims of international resting arrangements for seafarers. In the 3rd officers with higher MET, higher corelation between sleep efficiency and MET suggest that neuroscience needs more studies on the effects of physical energy consumption on the brain. [ABSTRACT FROM AUTHOR]

Published
2018

24. Surgical treatment in refractory epilepsy: seizure outcome results based on invasive EEG monitorization

Author

Aydin Aydoseli, Nermin Gorkem Sirin, Betül Tekin Güveli, Altay Sencer, Yavuz Aras, Sibel Velioglu, Zahide Mail Gurkan, Ulger Aydogan Culha, Akin Sabanci, Aysen Gokyigit, Ali Canbolat, Candan Gürses, Nerses Bebek, Fulya Eren, Bülent Kara, Günay Gül, Betül Baykan, Gürses, Rabia Candan (ORCID 0000-0002-3752-1825 & YÖK ID 110149), Mail Gürkan, Zahide, Şirin, Nermin Görkem, Kara, Bülent, Gül, Günay, Şengül Eren, Fulya, Tekin Güveli, Betül, Velioğlu, Sibel, Sabancı, Akin, Aydoseli, Aydın, Aras, Yavuz, Bebek, Nerses, Baykan, Betül, Sencer, Altay, Canbolat, Ali Tuncay, Gökyigit, Ayşen, Aydoğan Culha, Ülger, and School of Medicine

Subjects
Adult, Male, Drug Resistant Epilepsy, Pediatrics, medicine.medical_specialty, Clinical neurology, Surgery, Epilepsy, Seizures, medicine, Humans, Epilepsy surgery, Retrospective Studies, Hippocampal sclerosis, business.industry, Refractory epilepsy, Invasive EEG monitoring, Outcome, Eloquent cortex, Electroencephalography, Retrospective cohort study, Sequela, Cortical dysplasia, medicine.disease, Engel classification, Magnetic Resonance Imaging, Treatment Outcome, Etiology, Female, Neurology (clinical), business
Abstract

Aim: to discuss seizure outcomes of patients with invasive electroencephalography (EEG) monitorization (IEM) following their epilepsy surgery at our centre. Material and Methods: forty-seven patients suffering from refractory epilepsy and who were evaluated by invasive EEG were included in this retrospective study at Istanbul Faculty of Medicine from 2003 to 2017. We examined the Video EEG and invasive EEG monitorization, cranial MRI, SPECT, PET and neuropsychological tests of all patients. Postoperative seizure outcome results were evaluated according to Engel classification. The factors affecting seizure outcomes were discussed. Results: twenty-six of the patients were female (55.3%), 21 were male (44.7). The average age was 32.0 (+/- 12.4). Forty-three patients had surgery and the average age of these patients was 26,6 (+/- 11.15). 38.3% of the patients had hippocampal sclerosis (HS), 23.4% had focal cortical dysplasia (FCD), 8.5% had a tumor, 14.9% had sequela lesion and 14.9% had unknown etiology. Postoperative seizure status according to the Engel classification showed that 81.6% of the patients were class I, 10.5% were class II, 2.6% were class III and 5.3% were class IV. Conclusion: a significant relation was statistically determined between structural MRI lesion and favorable seizure outcome (p0.05). We argue that IEM is an essential examination for favorable outcomes for determining the epileptogenic zone and/or the proximity of the functional structures., NA

Published
2022

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