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Asthma is a very common chronic disease among preschool children in primary health care. Research has shown that planned and systematic patient education positively affects the management of asthma by parents. This study focuses on the question of whether an asthma patient education protocol that is used by general practitioners (GPs) has an effect on medical care consumption. The treatment group consisted of 28 GPs, representing 47 asthmatic infants. The control group contained 18 GPs, representing 38 patients. Data were collected from medical records (with a written instrument) for a 12-month period preceding and after the intervention period in which the education protocol was tested. Results indicated that sociodemographic variables and pretest data on asthma severity and medical care utilization were largely comparable for patients in both study groups. Furthermore, the treatment group showed a significantly greater decrease than the control group from pre- to post-test measurement in the number of contacts with the GP and the number of emergency visits to the physician's office.

Sendai virus infected a hysterectomy derived, barrier maintained breeding colony and a conventional aging rat colony. The virus produced seroconversion in the colonies followed by a 7-month period of decreasing titers. Clinical signs were absent during the months when titers were highest, and there was no increase in mortality, but multifocal interstitial pneumonia with perivascular and peribronchial cuffing by lymphocytes and plasma cells was present in rat lungs examined histologically. Such lesions were absent before the period of seroconversion. During the months of declining titers, the interstitial and perivascular lesions decreased in frequency and severity. The peribronchial lesions did not decrease, however, and were still present in many rats 7 months after the acute infection. Attempts to isolate the virus from weanling rats were unsuccessful.

An acute Sendai virus epizootic occurred simultaneously in a breeding colony, in experimental and stock animal rooms, and in a colony of aging mice. During the 2-month period that the infection was at its maximum, death rates were approximately doubled. In some strains, the preweanling death rate reached 100%. RFM and BALB/c mice were most susceptible and NZB mice least susceptible. The mortality during the period of Sendai virus infection was increased for most strains and age groups except for the oldest female RFM and NZB mice. Death rates during the epizootic were lowest in young adult mice (greater than 10 weeks of age) and highest in the very young mice (less than 10 weeks of age) and in the oldest male and the moderately aged female mice. Although a substantial number of older mice died during the epizootic, examination of the age-specific death rates indicated that the increase in deaths remained relatively constant for all ages over 10 weeks. This showed that the older mice were not more susceptible to Sendai virus infection. As a sequela of the epizootic, focal chronic pneumonia was found in 10-40% of the mice coming to necropsy even 1 year later.