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Made available in DSpace on 2022-04-28T19:49:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01 We sought to investigate the acute effects of capsaicin supplementation on the rate of perceived exertion (RPE) and heart rate during high-intensity intermittent exercise (HIIE) and resistance exercise performance executed after HIIE in resistance-trained men. Eleven resistance-trained men completed 2 randomized, double-blind trials: capsaicin condition or a placebo condition. The concurrent exercise session was composed of a 5-km intermittent run (1:1 effort and passive recovery ratio) and subsequent resistance exercise (4 × 70% of 1RM until muscle failure in the half-squat exercise). Heart rate was recorded during HIIE and after the protocol RPE (0–10 scale) was accessed. The resistance exercise performance was analyzed by the maximum number of repetitions performed for each set and the total volume (repetitions 3 weight lifted). During HIIE, the RPE (capsaicin = 7 ± 1 vs. placebo = 8 ± 1 points, t = -3.674, p = 0.005) and mean heart rate (capsaicin = 153 ± 13 vs. placebo = 158 ± 12 bpm, t = -2.292, p = 0.048) were significantly lower in the capsaicin compared with placebo condition. For subsequent resistance exercise, there was a significant decrease in volume across time (F = 19.889, p< 0.001, η2 = 0.69) with maximal number of repetitions performed in capsaicin than placebo condition (2,077.6 ± 465.2 kg vs. 1,838.9 ± 624.1 kg, p = 0.028, d = 0.43), but the condition vs. set was not significant (F = 0.582, p = 0.632, η2 = 0.06). Acute capsaicin supplementation induced a lower mean heart rate and RPE during HIIE and improved subsequent resistance exercise performance in resistance-trained men. Skeletal Muscle Assessment Laboratory (LABSIM) Department of Physical Education School of Technology and Sciences São Paulo State University (UNESP) Department of Physical Education Center University of Adamantina (UNIFAI) Department of Nutrition University of Western São Paulo (UNOESTE) Department of Kinesiology Coastal Carolina University School of Physical Education and Sport University of São Paulo Exercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP), SP Immunometabolism of Skeletal Muscle and Exercise Research Group Department of Physical Education Federal University of Piauí (UFPI), PI Associate Graduate Program in Health Science Federal University of Piauí (UFPI), PI Skeletal Muscle Assessment Laboratory (LABSIM) Department of Physical Education School of Technology and Sciences São Paulo State University (UNESP) Exercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP), SP

Made available in DSpace on 2019-10-06T16:46:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) The present study sought to clarify the impact of exercise intensity and timing on energy intake and appetite-related blood variables. Fourteen inactive overweight men were included in the study. Firstly, maximal aerobic power (MAP) was measured. Then, participants randomly performed 5 experimental sessions consisting of 30 min of steady-state exercise (SSE) at 50% of MAP, high-intensity intermittent exercise (HIIE) with 30s repetitions at MAP and 30s of passive recovery or no exercise (CTRL). Sessions were performed 1h (SSE1h and HIIE1h) or 2.5h (SSE2.5h and HIIE2.5h) after the consumption of a standardized breakfast. An ad libitum buffet was offered 3.5h after the completion of the breakfast. Absolute energy intake (EI) and relative energy intake (REI) (relative energy intake = energy intake - energy expenditure from exercise) were measured. Appetite (hunger, fullness and desire for specific foods) scores and circulating concentration of insulin and IL-6 were determined at 1h, 1.75h, 2.5h and 3.25h after breakfast while lactate was measured post-exercise. EI was greater after the CTRL session compared to HIIE2.5h (5045.9 ± 1873.5 kJ vs. 3716.1 ± 1688.7 kJ). REI was greater for the CTRL session (5045.9 ± 1873.5 kJ) than HIIE1h (3386.5 ± 1660.1 kJ), HIIE2.5h (2508.5 ± 1709.3 kJ) and SSE2.5h (3426.6 ± 1788.0 kJ). Higher hunger scores were observed following the CRTL session with respect to those of HIIE2.5h. Insulin and IL-6 concentrations were greater after HIIE1h and SSE1h with respect to those obtained after HIIE2.5h, SSE2.5h and CTRL. Lactate concentrations were higher in HIIE1h and HIIE2.5h compared to those of SSE1h and SSE2.5h. These results show that HIIE performed 2.5h after a breakfast reduced appetite (hunger scores) and EI through mechanism that need to be characterized. This approach can be applied to individuals aiming to create an energetic deficit. School of Physical Education and Sport University of São Paulo Department of Exercise Sciences Université du Québec à Montréal Centre de Recherche du CHU Sainte-Justine School of Public Health University of São Paulo Exercise and Immunometabolism Research Group Postgraduation Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP), Presidente Prudente Exercise and Immunometabolism Research Group Postgraduation Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP), Presidente Prudente CNPq: 150549/2016-4 FAPESP: 2015/11302-3 FAPESP: 2017/07304-6 FAPESP: 2017/08167-2 FAPESP: 2017/19280-4 CNPq: 402629/2016-7 CNPq: 800585/2016-0

(1) Background: We investigated the effects of 28 days of beta-alanine (&beta, alanine) supplementation on the acute interference effect of high-intensity intermittent exercise (HIIE) on lower-body resistance exercise performance, body composition, and strength when combined with a resistance training program. (2) Methods: Twenty-two males were randomized into: &beta, alanine supplementation (6.4 g/day) or placebo (6.4 g/day maltodextrin) during 28 days. Total body water, intracellular and extracellular water, fat-free mass (FFM), and fat mass were assessed using bioelectrical impedance. Participants performed 5000-m HIIE (1:1 effort and rest ratio) followed by resistance exercise (four sets of 80% at 45&deg, leg press until muscular failure) at baseline and after 28 days. The resistance training program consisted of three sets of 10 to 12 RM with 90 s of rest, four days per week. (3) Results: For the post-HIIE leg press volume, higher values were observed post-training than pre-training, but no group x time interaction was observed. There was a non-significant trend for an interaction in the FFM change (&beta, alanine = 2.8% versus placebo = 1.0%, p = 0.072). (4) Conclusion: Twenty-eight days of &beta, alanine supplementation did not prevent acute strength loss during resistance exercise after high-intensity interval exercise, nor increase strength or hypertrophic adaptations associated with resistance training.

Made available in DSpace on 2019-10-06T15:34:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-03-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Purpose: To compare the acute and chronic effects of high-intensity intermittent training (HIIT) and moderate-intensity continuous training (MICT) on indices of cardio-metabolic health: (HDL-c, total cholesterol, triglycerides, heart ratio, and phase angle/PhA) in physically active men. Methods: Twenty active men were randomly allocated to HIIT (n = 10), or MICT (n = 10) for 5 weeks, three times per week. HIIT consisted of running 5 km with 1-min at 100% of maximal aerobic speed interspersed by 1-min passive recovery while subjects in MICT group ran continuously the same 5 km at 70% of maximal aerobic speed. Blood samples were collected at different moments during the first and last exercise session. Before and after 5 weeks of both exercise training protocols, heart ratio (during exercise session) and PhA were measured pre and post-exercise training. Results: Fasting HDL-c levels did not change after 5 weeks of HIIT or MICT. Perceptual variation of HDL pre and post training (fed state) tended to differ between HIIT and MICT (p = 0.09). All lipoproteins parameters (HDL-c, total cholesterol, triglycerides and non-HDL) were increased in post-acute exercise session compared to pre-exercise during the first and last training session, these being observed after both training protocols. PhA and heart rate measured at different times during the first and last training session were not affected in both training protocols. Conclusion: These results indicate that HIIT and MICT modify the post-exercise lipoprotein profile acutely. On the other hand, only HIIT tended to increase HDL-c levels chronically. Exercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP) School of Technology and Sciences Post Graduation Program in Motricity Sciences São Paulo State University (UNESP) Post Graduation Program in Physical Therapy São Paulo State University (UNESP) Department of Physical Education Federal University of Pernambuco School of Physical Education and Sport University of São Paulo Department of Exercise Sciences Université du Québec à Montréal Centre de Recherche du CHU Sainte-Justine Department of Kinesiology University of Montreal Exercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP) School of Technology and Sciences Post Graduation Program in Motricity Sciences São Paulo State University (UNESP) Post Graduation Program in Physical Therapy São Paulo State University (UNESP) FAPESP: 20 15/23127-1 FAPESP: 2015/11302-3 FAPESP: 2016/16712-8

The purpose of this study was to compare the effect of high-intensity intermittent exercise (HIIE) versus volume matched steady state exercise (SSE) on inflammatory and metabolic responses. Eight physically active male subjects completed two experimental sessions, a 5-km run on a treadmill either continuously (70% vVO2max) or intermittently (1:1 min at vVO2max). Blood samples were collected at rest, immediately, 30 and 60 minutes after the exercise session. Blood was analyzed for glucose, non-ester fatty acid (NEFA), uric acid, lactate, cortisol, and cytokines (IL-6, IL-10 and TNF-α) levels. The lactate levels exhibited higher values immediately post-exercise than at rest (HIIE 1.34 ± 0.24 to 7.11 ± 2.85, and SSE 1.35 ± 0.14 to 4.06±1.60 mmol·L-1, p < 0.05), but HIIE promoted higher values than SSE (p < 0.05); the NEFA levels were higher immediately post-exercise than at rest only in the SSE condition (0.71 ± 0.04 to 0.82±0.09 mEq/L, respectively, p < 0.05), yet, SSE promoted higher values than HIIE immediately after exercise (HIIE 0.72±0.03 vs SSE 0.82±0.09 mEq·L-1, p < 0.05). Glucose and uric acid levels did not show changes under the different conditions (p > 0.05). Cortisol, IL-6, IL-10 and TNF-α levels showed time-dependent changes under the different conditions (p < 0.05), however, the area under the curve of TNF-α in the SSE were higher than HIIE (p < 0.05), and the area under the curve of IL-6 in the HIIE showed higher values than SSE (p < 0.05). In addition, both exercise conditions promote increased IL-10 levels and IL-10/TNF-α ratio (p < 0.05). In conclusion, our results demonstrated that both exercise protocols, when volume is matched, promote similar inflammatory responses, leading to an anti-inflammatory status; however, the metabolic responses are different.

Made available in DSpace on 2018-12-11T17:15:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-10-31 Purpose: To compare the acute and chronic effects of high intensity intermittent training (HIIT) and steady state training (SST) on the metabolic profile and inflammatory response in physically active men. Methods: Thirty recreationally active men were randomly allocated to a control group (n = 10), HIIT group (n = 10), or SST group (n = 10). For 5 weeks, three times per week, subjects performed HIIT (5 km 1-min at 100% of maximal aerobic speed interspersed by 1-min passive recovery) or SST (5 km at 70% of maximal aerobic speed) while the control group did not perform training. Blood samples were collected at fasting (~12 h), pre-exercise, immediately post, and 60 min post-acute exercise session (pre- and post-5 weeks training). Blood samples were analyzed for glucose, non-ester fatty acid (NEFA), and cytokine (IL-6, IL-10, and TNF-α) levels through a three-way analysis (group, period, and moment of measurement) with repeated measures in the second and third factors. Results: The results showed an effect of moment of measurement (acute session) with greater values to TNF-α and glucose immediately post the exercise when compared to pre exercise session, independently of group or training period. For IL-6 there was an interaction effect for group and moment of measurement (acute session) the increase occurred immediately post-exercise session and post-60 min in the HIIT group while in the SST the increase was observed only 60 min post, independently of training period. For IL-10, there was an interaction for training period (pre- and post-training) and moment of measurement (acute session), in which in pre-training, pre-exercise values were lower than immediately and 60 min post-exercise, in post-training period pre-exercise values were lower than immediately post-exercise and immediately post-exercise lower than 60 min post, it was also observed that values immediately post-exercise were lower pre- than post-training, being all results independently of intensity (group). Conclusion: Our main result point to an interaction (acute and chronic) for IL-10 showing attenuation post-training period independent of exercise intensity. Exercise and Immunometabolism Research Group Department of Physical Education State University (Unesp) School of Technology and Sciences Presidente Prudente Department of Sport School of Physical Education and Sport University of São Paulo Department of Physical Education Federal University of Pernambuco Faculty of Physical Education University of Campinas Exercise and Immunometabolism Research Group Department of Physical Education State University (Unesp) School of Technology and Sciences Presidente Prudente

Made available in DSpace on 2018-12-11T16:46:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-02-25 The aim of this study was to investigate the physiological responses to moderate-intensity continuous and high-intensity intermittent exercise. Twelve physically active male subjects were recruited and completed a 5-km run on a treadmill in two experimental sessions in randomized order: continuously (70% sVO2max) and intermittently (1:1 min at sVO2max). Oxygen uptake, excess post-exercise oxygen consumption, lactate concentration, heart rate and rating of perceived exertion data were recorded during and after each session. The lactate levels exhibited higher values immediately post-exercise than at rest (High-Intensity: 1.43 ± 0.25 to 7.36 ± 2.78; Moderate-Intensity: 1.64 ± 1.01 to 4.05 ± 1.52 mmol·L-1, p = 0.0004), but High-Intensity promoted higher values (p = 0.001) than Moderate-Intensity. There was a difference across time on oxygen uptake at all moments tested in both groups (High-Intensity: 100.19 ± 8.15L; Moderate-Intensity: 88.35 ± 11.46, p < 0.001). Both exercise conditions promoted increases in excess postexercise oxygen consumption (High-Intensity: 6.61 ± 1.85 L; Moderate-Intensity: 5.32 ± 2.39 L, p < 0.005), but higher values were observed in the High-Intensity exercise protocol. High-Intensity was more effective at modifying the heart rate and rating of perceived exertion (High-Intensity: 183 ± 12.54 and 19; Moderate-Intensity: 172 ± 8.5 and 16, respectively, p < 0.05). In conclusion, over the same distance, Moderate-Intensity and High-Intensity exercise exhibited different lactate concentrations, heart rate and rating of perceived exertion. As expected, the metabolic contribution also differed, and High-Intensity induced higher energy expenditure, however, the total duration of the session may have to be taken into account. Moreover, when following moderate-intensity training, the percentage of sVO2max and the anaerobic threshold might influence exercise and training responses. Exercise and Immunometabolism Research Group Department of Physical Education Universidade Estadual Paulista (UNESP) Department of Kinesiology Coastal Carolina University Department of Physical Education Universidade Federal de Pernambuco, Avenida Professor Moraes Rego, 1235 Department of Sports School of Physical Education and Sports University of São Paulo Exercise and Immunometabolism Research Group Department of Physical Education Universidade Estadual Paulista (UNESP)

Made available in DSpace on 2018-12-11T16:43:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-12-01 Purpose: To compare the effects of the order of concurrent exercise (endurance plus strength or strength plus endurance) on lipoprotein profiles in men. Methods: After the evaluation of maximum strength (one repetition maximum—1RM) in the half-squat and of aerobic fitness (maximal velocity in treadmill incremental test), 11 physically active male subjects underwent two randomized sessions composed of four sets of half-squat strength exercises until exhaustion (at 80 % of 1RM) and a 5-km run high-intensity intermittent exercise (1:1 min at Vmax), performed in different orders: (1) strength plus run (S-A) and inverse order, and run plus strength (A-S). Blood samples were collected before and immediately after the first exercise (Post-1) and after the second exercise (Post-2) in the intra-session sequence. Serum was analyzed for total cholesterol (TC) and its ratio, HDL-c and LDL-c, and triacylglycerol (TAG). Results: There were effects of condition for TC, LDL-c, and TC/HDL, with greater values in the AS than SA (p

Panissa VLG, Julio UF, Pinto e Silva CM, Andreato LV, Hardt F, Franchini E. Effects of interval time between high-intensity intermittent aerobic exercise on strength performance: analysis in individuals with different training background. J. Hum. Sport Exerc. Vol. 7, No. 4, pp. 815-825, 2012. This study aimed to analyze the effect of the time interval after high-intensity aerobic exercise on strength performance in individuals with different training backgrounds. Participants (n = 27) were divided into three groups according to their training backgrounds (aerobic, strength or concurrent) and submitted to eight sessions: (1) determination of the peak velocity (Vpeak) during the incremental treadmill test to exhaustion and familiarization of the evaluation of maximum strength (1RM) for the half-squat; (2) 1RM determination; and (3-8) randomly assigned experimental sessions consisting of either a strength exercise (SE), four sets at 80% of the 1RM, in which maximum number of repetitions (MNR) and the total volume performed (TV) was computed, and five sessions consisting of high-intensity intermittent aerobic exercise (100% of Vpeak - 1 min:1 min) totaling 5 km, followed by a SE with varying recovery intervals between activities (30, 60 minutes, 4, 8, and 24 hours). Comparisons for MNR and TV were made using two-way variance analysis (group and time interval) with repeated measures in the second factor. When significant differences were detected (P < 0.05), a Bonferroni and Dunnet post-hoc test were used. There was an effect of group for MNR, with the Aerobic Group performing a higher MNR compared to Strength Group (P = 0.002). Moreover, there was an effect of the time interval for MNR and TV, with reduction after 30 (P < 0.001 for both variables) and 60 minutes intervals (P = 0.035; P = 0.007, respectively) compared to the control condition. Thus, it is concluded that the drop in performance related to the SE activity occurred with the

Made available in DSpace on 2018-11-26T16:48:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-06-28 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Purpose: The present study investigated the effects of high-intensity intermittent training (HIIT) on lower- and upper-body graded exercise and high-intensity intermittent exercise (HIIE, four Wingate bouts) performance, and on physiological and muscle damage markers responses in judo athletes. Methods: Thirty-five subjects were randomly allocated to a control group (n = 8) or to one of the following HIIT groups (n = 9 for each) and tested pre- and post-four weeks (2 training d center dot wk(-1)): (1) lower-body cycle-ergometer; (2) upper-body cycle-ergometer; (3) uchi-komi (judo technique entrance). All HIIT were constituted by two blocks of 10 sets of 20 s of all out effort interspersed by 10 s set intervals and 5-min between blocks. Results: For the upper-body group there was an increase in maximal aerobic power in graded upper-body exercise test (12.3%). The lower-body group increased power at onset blood lactate in graded upper-body exercise test (22.1%). The uchi-komi group increased peak power in upper- (16.7%) and lower-body (8.5%), while the lower-body group increased lower-body mean power (14.2%) during the HIIE. There was a decrease in the delta blood lactate for the uchi-komi training group and in the third and fourth bouts for the upper-body training group. Training induced testosterone-cortisol ratio increased in the lower-body HIIE for the lower-body (14.9%) and uchi-komi (61.4%) training groups. Conclusion: Thus, short-duration low-volume HIIT added to regular judo training was able to increase upper-body aerobic power, lower- and upper-body HIIE performance. Univ Sao Paulo, Sch Phys Educ & Sport, Dept Sport, Sao Paulo, Brazil Univ Estadual Paulista, Dept Phys Educ, Exercise & Immunometab Res Grp, Presidente Prudente, Brazil Univ Estadual Paulista, Dept Phys Educ, Exercise & Immunometab Res Grp, Presidente Prudente, Brazil FAPESP: 2011/22105-3 FAPESP: 2011/22862-9 FAPESP: 2012/00220-8 CNPq: 302242/2014-7

O objetivo do presente estudo foi analisar o efeito da ordem de execução dos exercícios de força e aeróbio sobre o gasto energético total na sessão. Para isso, dez homens tiveram seu consumo de oxigênio medido continuamente durante as seguintes sessões: aeróbio-força (AF) e força-aeróbio (FA). O exercício aeróbio consistiu de 30 minutos de corrida na esteira a 90% da velocidade do limiar anaeróbio. A sessão de força foi composta de quatro exercícios, na qual os participantes realizavam três séries de 12 repetições a 70% de 1RM. A concentração de lactato sanguíneo [La] foi mensurada após cada exercício de força e nos minutos 10, 20 e 30 do exercício aeróbio. A [La] durante a execução do exercício aeróbio permaneceu maior (p < 0,05) na situação FA quando comparado com a AF aos 10 (FA = 5,1 ± 1,3mmol.l-1; AF = 3,2 ± 1,0mmol.l-1), 20 (FA = 4,2 ± 1,0mmol.l-1; AF = 3,0 ± 0,9mmol.l-1) e 30 minutos (FA = 3,9 ± 1,3mmol.l-1; AF = 3,4 ± 1,1mmol.l-1). O gasto energético total não diferiu entre as ordens de exercício (FA = 2.793 ± 811kJ; AF = 2.893 ± 903 kJ; p > 0,05), indicando que a ordem de execução não afetou significativamente o gasto energético.The aim of present study was to analyze the effect of aerobic and strength exercises order on the total energy expenditure in an exercise session. Ten male subjects had their VO2 continuously measured during two sessions: aerobic-resistance (AR) and resistance-aerobic (RA) to estimate caloric expenditure. The aerobic session was a 30-min treadmill run at 90% of anaerobic threshold velocity. The strength exercise session had four exercises, where participants performed three sets of 12 repetitions at 70% of 1RM. Blood lactate concentration (LA) was measured after each strength exercise and at 10, 20 and 30 min during the aerobic exercise. LA during aerobic exercise was higher (p < 0.05) in RA order when compared to AR at 10 (RA = 5.1 ± 1.3 mmol.l-1; AR = 3.2 ± 1.0 mmol.l-1), 20 (RA = 4.2 ± 1.0 mmol.l-1; AR = 3.0 ± 0.9 mmol.l-1) and 30-min (RA = 3.9 ± 1.3 mmol. l-1; AR = 3.4 ± 1.1 mmol.l-1). Total caloric expenditure did not differ between exercise orders (RA = 2793 ± 811 kJ; AR = 2893 ± 903 kJ; p > 0.05), indicating that performance order did not affect energy expenditure.