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The major current overviews establish that generalized development stress between ages 0-5 underlines most permanent tooth hypoplasias. Fluoridation of metropolitan water has emerged as the statistically strongest hypoplasia-preventing factor.

The human dentition is a complex adaptive system that is influenced by genetic, epigenetic, and environmental factors. Within this system, is sexual dimorphism related to the growth promotion of the Y chromosome, or to hormonal influences, or both? This study is the first to investigate both primary and permanent tooth sizes in females from opposite-sex dizygotic (DZOS) twin pairs compared with females from dizygotic same-sex (DZSS) and monozygotic (MZ) twin pairs to indicate the influence of intrauterine male hormone, including the initial testosterone surge, on dental development. Serial dental models of the primary, mixed, and permanent dentitions of 134 females from DZOS, DZSS, and MZ twins were examined. Mesiodistal, buccolingual, crown height, and intercuspal dimensions of all primary teeth and selected permanent teeth were determined by image analysis. Univariate and multivariate analyses showed statistically significantly larger crown size in DZOS females in both dentitions, with the crown height dimensions displaying the greatest increase in size. These findings strongly support the Twin Testosterone Transfer (TTT) hypothesis. We propose that the growth-promoting effects of the Y chromosome and intrauterine male hormone levels influence different tooth dimensions and contribute differentially to the sexual dimorphism of human teeth. [ABSTRACT FROM PUBLISHER]

Objective: To investigate facial asymmetry associated with both deformational and synostotic plagiocephaly and to identify variables based on skeletal landmarks that distinguish the conditions and quantify severity. Design: Retrospective, cross sectional. Setting: Australian Craniofacial Unit, Adelaide. Main Outcome Measures: Proportional differences between bilateral distances and principal component (PC) analysis of the skeletal landmarks. Patients: The three-dimensional positions of 78 osseous landmarks were determined from computed tomography (CT) scans of 21 patients with deformational plagiocephaly (DP), 20 patients with unilateral coronal synostosis (UCS), and 2 patients with unilateral lambdoid synostosis (ULS). Results: For both DP and UCS, significant asymmetry was found for the orbital depths, mandibular lengths, maxillary depths, zygomatic arch lengths, lateral base of the parietal bone, and the angle between the anterior and the posterior cranial base projected onto the axial plane. The small sample size for ULS precluded definitive statistical statements but allowed some useful comparisons with the other conditions. The first three PC scores were able to distinguish among the three conditions and which side was affected. Conclusions: The asymmetry of the cranial base and facial structures, arising from localized abnormality or deformational forces in either the frontal or the occipital regions, can be quantified by a plethora of bilateral features or summarized by PC analysis. [ABSTRACT FROM AUTHOR]

Background: Easily applied, age-specific standards are useful in assisting clinicians to decide whether the extent of tooth wear observed in a given patient at a specific age is acceptable or whether intervention is indicated. Method: A simple method of scoring tooth wear and previously established mathematical relationships between tooth wear scores and age, provide the basis of a method for predicting tooth wear scores. In its most specific form, the method can be used to predict tooth wear scores for individual patients at subsequent ages. Alternatively, tables or graphs can be consulted to provide a less precise prediction of tooth wear that can assist clinicians to decide whether the amount of wear reflects high, moderate or low rates of wear at the specified age. Conclusion: In cases where there is no reason to believe that aetiological factors have changed significantly over time, data obtained from the methods described can assist clinicians to plan appropriate management for patients presenting with unacceptable levels of tooth wear. Key words: Tooth wear; attrition; erosion; abrasion; scoring. [ABSTRACT FROM AUTHOR]

The nature and frequency of dental wear facets were studied in a sample of 18-year-old Aborigines, 28 males and 31 females, living at Yuendumu in the Northern Territory of Australia. Facet frequencies were scored indirectly using dental models for all permanent teeth, except third molars, and evidence of non-masticatory tooth grinding in eccentric jaw positions was also recorded. The interplay between attrition and abrasion in an individual over time was assessed by examining facet appearance on serial dental models obtained at approximately yearly intervals from 7 to 25 years of age. Facetting was found to be a very common feature of the Aboriginal dentitions, with frequencies ranging from around 65% for pre-molars to about 90% for molars. Evidence of extreme mandibular movement was noted in 93% of males and 100% of females. The longitudinal observations indicated that wear facet definition varied over time, apparently due to episodes of tooth grinding superimposed on continually-acting abrasive influences. These results show that facetting on teeth associated with extreme mandibular positions and, by inference, the related behaviour of tooth grinding or bruxism are very common features in dentitions of Australian Aboriginals living an essentially non-industrial way of life. [ABSTRACT FROM AUTHOR]

Abstract: Aims: Anomalies of tooth number may not be isolated conditions but may have wider associations in the development of the dentition including tooth size. This study aimed to examine links between hypodontia, supernumerary teeth and crown size, considering the effect on the development of the whole dentition and so increase understanding of the aetiology of these conditions. Methods and results: The patients, who were all of European ancestry, were 60 young adults (30 males and 30 females) with hypodontia and 60 age and sex matched controls together with 60 young adults (39 males and 21 females) with supernumerary teeth and 60 age and sex matched controls. Hand measurements of mesiodistal and buccolingual dimensions were made of the teeth on dental study models using Mitutoyo electric callipers. The mean value of two measurements was used and intra-operator and inter-operator reliability determined. Patients with hypodontia had smaller teeth than the control group and this difference was statistically significant (p <0.05) for all teeth except the MD dimensions of 13, 23, 24 and 44. The difference in size was greatest for the BL dimensions in hypodontia patients. Further, the greater the number of missing teeth the smaller the tooth size. The hypodontia patients also showed higher variability in tooth dimensions than the control group. Patients with supernumerary teeth had larger teeth than the controls, with the greatest differences in the MD dimensions. In both hypodontia and supernumerary patients the differences in tooth size were generalised throughout the dentition. Conclusions: In anomalies of tooth number the size of teeth is also involved. In patients with hypodontia and supernumerary teeth the crown size of the whole dentition is affected. These findings are compatible with a multifactorial aetiology of these conditions. [Copyright &y& Elsevier]