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Cancer is a multifaceted disease that results from the complex interaction between genetic and environmental factors. Cancer is a mortal disease with the biggest clinical, societal, and economic burden. Research on better methods of the detection, diagnosis, and treatment of cancer is crucial. Recent advancements in material science have led to the development of metal–organic frameworks, also known as MOFs. MOFs have recently been established as promising and adaptable delivery platforms and target vehicles for cancer therapy. These MOFs have been constructed in a fashion that offers them the capability of drug release that is stimuli-responsive. This feature has the potential to be exploited for cancer therapy that is externally led. This review presents an in-depth summary of the research that has been conducted to date in the field of MOF-based nanoplatforms for cancer therapeutics. [ABSTRACT FROM AUTHOR]

In this study, a new method for preparation of cross-linked magnetic chitosan particles (MCPs) from steel slag and shrimp shells using green tea extract as crosslinking reagent has been presented. The MCPs obtained were characterized by means of X-ray diffraction analysis, Fourier-transform infrared spectroscopy, scanning electron microscopy and magnetic properties, and then were used to investigate the adsorption properties of Cu(II) and Ni(II) ions in aqueous solutions. The influence of experimental conditions such as contact time, pH value, adsorbent dose and initial metal concentration, and the possibility of regeneration were studied systematically. The Cu(II) and Ni(II) adsorption isotherms, kinetics and thermodynamics have been measured and discussed. The results show that the synthesized MCPs have high adsorption capacity for both metal ions (126.58 mg/g for Cu(II) and 66.23 mg/g for Ni(II)), and have excellent regeneration stability with efficiency of greater than 83% after five cycles of the adsorption-regeneration process. The adsorption process of Ni(II) and Cu(II) on MCPs was feasible, spontaneous and exothermic, and better described by the Langmuir model and pseudo-second-order kinetic equation. The MCPs can be applied as a low cost and highly efficient adsorbent for removal of heavy metals from wastewater due to its high adsorption capacity, easy recovery and good reusability. [ABSTRACT FROM AUTHOR]

• Rapid adsorption of Rhodamine B (Rh.B) by ZIF-8 under visible light irradiation. • Blue-shifted π –π* transition of aromatic π system of Rh.B adsorbed on the ZIF-8. • ZIF-8 generated hydroxyl radicals for the degradation of organic dye under UV light. • Density functional theory coupled with spectroscopic techniques were optimized. The adsorption of Rhodamine B (Rh.B) was achieved by Zeolite imidazolate framework-8 (ZIF-8) in the dark condition, and the adsorption rate was noticeably increased under visible and UV light irradiations. According to fluorescence spectroscopic studies, ZIF-8 under UV light generated hydroxyl radicals for the effective degradation of Rh.B dyes. These featured mechanisms were systematically elucidated by investigating the zeta potentials of ZIF-8/Rh.B; blue-shifted π –π* transition of aromatic system; chemical shift of 13C NMR spectra; FTIR spectra; and high surface area and abundant mesopores of ZIF-8. Furthermore, the interaction mechanism between Rh.B with ZIF-8 was studied using a density functional theory (DFT) coupled with a spectroscopic technique. Herein, nine ZIF-8 clusters and Rh.B molecules were optimized in aqueous solution using the polarizable continuum model to address the solvation effect. The DFT calculations suggested that π-π stacking interactions between the xanthene ring of Rh.B and the imidazole rings of ZIF-8 and electrostatic interactions between electron-deficient Zn centers and Rh.B predominantly contributed to the adsorption of Rh.B on the ZIF-8. The experimental and computations studies provide a new insight for the sophisticated design of ZIF-8 nanostructures for removing organic pollutants efficiently through the combined adsorption and degradation under solar light irradiation. [ABSTRACT FROM AUTHOR]