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International audience; Electrochemical water treatment is one of the key topics of environmental electrochemistry. Identifying electrocatalytic materials capable of electrogenerating high oxidant species in situ seems to have catalyzed researchers' interest in these processes. While most studies have focused on ideal lab-made solutions, translation to higher technology readiness levels and commercialization requires reframing research questions in context of real water matrices. In this current opinion, we discuss disconnects that may occur when focusing on synthetic solutions treatment rather than real waters. Future research can fill the gaps identified herein, thus facilitating application of electrochemical water treatment technologies.

Glucagon and glucagon-like peptide 1 (GLP-1) are drugs or drug candidates for the treatment of metabolic diseases such as diabetes and obesity. The native hormones have pharmacological deficiencies such as short half-life and poor solubility. A novel glucagon receptor agonist named glucagon-Cex has been designed, synthesized and crystallized. This peptide was highly soluble under physiological conditions and crystallized readily. The crystal diffracted X-rays to 2.2 A resolution and the diffraction was consistent with space group P23, with unit-cell parameters a = b = c = 48.20 A, alpha = beta = gamma = 90.0 degrees. The crystals were suitable for a full structural determination to reveal the conformational differences between glucagon-Cex and the native hormone.