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245 results on '"Sy, Raymond W."'

1. Mode and Characteristics of Arrhythmia Initiation in Idiopathic Ventricular Fibrillation: A THESIS Substudy

Author

Asatryan, Babken, Baskar, Shankar, Berne, Paola, Blommaert, Dominique, Dormal, Fabien, Boccellino, Antonio, Ciconte, Giuseppe, Giustetto, Carla, Haqqani, Harris, Jackson, Liang J., DG, Latcu, Lellouche, Nicolas, Marai, Ibrahim, Nakahara, Shiro, Pannone, Luigi, de Asmundis, Carlo, Pavri, Behzad B., Porretta, Alessandra Pia, Pruvot, Etienne, Rosu, Radu, Scherr, Daniel, Steinfurt, Johannes, Yagishita, Atsuhiko, Belhassen, Bernard, Conte, Giulio, Steinberg, Christian, Whitaker, John, Khan, Habib R., Laredo, Mikael, Doldi, Florian, Ho, Reginald, Tadros, Rafik, Dinov, Boris, Chorin, Ehud, Hansom, Simon, Waintraub, Xavier, Eckardt, Lars, Jankelson, Lior, Peichl, Petr, Mellor, Greg, Sy, Raymond W., Rattanawong, Pattara, Stojkovic, Stefan, Garber, Leonid, Suna, Gonca, Kautzner, Josef, Chan, Kim Hoe, Srivathsan, Komandoor, Tedrow, Usha, Havranek, Stepan, Murgatroyd, Francis, Shauer, Ayelet, Winkel, Bo Gregers, Page, Stephen P., Milman, Anat, Lador, Adi, Ayou, Romeo, Sellal, Jean Marc, Chevalier, Philippe, García-Fernández, F. Javier, Reichlin, Tobias, Shah, Dipen, Nazer, Babak, Bermudez-Jimenez, Francisco, Nagase, Satoshi, Morita, Hiroshi, Nam, Gi-Byoung, Pappone, Carlo, Lambiase, Pier D., Strohmer, Bernhard, Stuehlinger, Markus, Gandjbakhch, Estelle, Schulze-Bahr, Eric, Krahn, Andrew D., and Tovia-Brodie, Oholi

Published
2024
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2. 2023 Cardiac Society of Australia and New Zealand Expert Position Statement on Catheter and Surgical Ablation for Atrial Fibrillation

Author

Kistler, Peter M., Sanders, Prash, Amarena, John V., Bain, Chris R., Chia, Karin M., Choo, Wai-Kah, Eslick, Adam T., Hall, Tanya, Hopper, Ingrid K., Kotschet, Emily, Lim, Han S., Ling, Liang-Han, Mahajan, Rajiv, Marasco, Silvana F., McGuire, Mark A., McLellan, Alex J., Pathak, Rajeev K., Phillips, Karen P., Prabhu, Sandeep, Stiles, Martin K., Sy, Raymond W., Thomas, Stuart P., Toy, Tracey, Watts, Troy W., Weerasooriya, Rukshen, Wilsmore, Bradley R., Wilson, Lauren, and Kalman, Jonathan M.

Published
2024
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4. Clinical Management of Brugada Syndrome: Commentary From the Experts

Author

Cutler, Michael J., Eckhardt, Lee L., Kaufman, Elizabeth S., Arbelo, Elena, Behr, Elijah R., Brugada, Pedro, Cerrone, Marina, Crotti, Lia, deAsmundis, Carlo, Gollob, Michael H., Horie, Minoru, Huang, David T., Krahn, Andrew D., London, Barry, Lubitz, Steven A., Mackall, Judith A., Nademanee, Koonlawee, Perez, Marco V., Probst, Vincent, Roden, Dan M., Sacher, Frederic, Sarquella-Brugada, Georgia, Scheinman, Melvin M., Shimizu, Wataru, Shoemaker, Benjamin, Sy, Raymond W., Watanabe, Atsuyuki, and Wilde, Arthur A.M.

Published
2024
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10. The role of genetic testing in diagnosis and care of inherited cardiac conditions in a specialised multidisciplinary clinic

Author

Stafford, Fergus, Krishnan, Neesha, Richardson, Ebony, Butters, Alexandra, Hespe, Sophie, Burns, Charlotte, Gray, Belinda, Medi, Caroline, Nowak, Natalie, Isbister, Julia C., Raju, Hariharan, Richmond, David, Ryan, Mark P., Singer, Emma S., Sy, Raymond W., Yeates, Laura, Bagnall, Richard D., Semsarian, Christopher, and Ingles, Jodie

Published
2022
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17. Management of Congenital Long-QT Syndrome: Commentary From the Experts

Author

Kaufman, Elizabeth S., Eckhardt, Lee L., Ackerman, Michael J., Aziz, Peter F., Behr, Elijah R., Cerrone, Marina, Chung, Mina K., Cutler, Michael J., Etheridge, Susan P., Krahn, Andrew D., Lubitz, Steven A., Perez, Marco V., Priori, Silvia G., Roberts, Jason D., Roden, Dan M., Schulze-Bahr, Eric, Schwartz, Peter J., Shimizu, Wataru, Shoemaker, M. Benjamin, Sy, Raymond W., Towbin, Jeffrey A., Viskin, Sami, A.M. Wilde, Arthur, and Zareba, Wojciech

Published
2021
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29. Predicting adverse outcomes following catheter ablation treatment for atrial fibrillation

Author

Quiroz, Juan C., Brieger, David, Jorm, Louisa, Sy, Raymond W, Hsu, Benjumin, and Gallego, Blanca

Subjects
FOS: Computer and information sciences, Computer Science - Machine Learning, Statistics - Other Statistics, J.3, Other Statistics (stat.OT), FOS: Biological sciences, G.3, Quantitative Biology - Quantitative Methods, Quantitative Methods (q-bio.QM), Machine Learning (cs.LG)
Abstract

Objective: To develop prognostic survival models for predicting adverse outcomes after catheter ablation treatment for non-valvular atrial fibrillation (AF). Methods: We used a linked dataset including hospital administrative data, prescription medicine claims, emergency department presentations, and death registrations of patients in New South Wales, Australia. The cohort included patients who received catheter ablation for AF. Traditional and deep survival models were trained to predict major bleeding events and a composite of heart failure, stroke, cardiac arrest, and death. Results: Out of a total of 3285 patients in the cohort, 177 (5.3%) experienced the composite outcome (heart failure, stroke, cardiac arrest, death) and 167 (5.1%) experienced major bleeding events after catheter ablation treatment. Models predicting the composite outcome had high risk discrimination accuracy, with the best model having a concordance index > 0.79 at the evaluated time horizons. Models for predicting major bleeding events had poor risk discrimination performance, with all models having a concordance index < 0.66. The most impactful features for the models predicting higher risk were comorbidities indicative of poor health, older age, and therapies commonly used in sicker patients to treat heart failure and AF. Conclusions: Diagnosis and medication history did not contain sufficient information for precise risk prediction of experiencing major bleeding events. The models for predicting the composite outcome have the potential to enable clinicians to identify and manage high-risk patients following catheter ablation proactively. Future research is needed to validate the usefulness of these models in clinical practice., Under journal review; updated in response to reviewer comments

Published
2022

32. Prognostic benefit of catheter ablation of atrial fibrillation in heart failure: An updated meta‐analysis of randomized controlled trials.

Author

Virk, Sohaib A., Hyun, Karice, Brieger, David, and Sy, Raymond W.

Subjects
ATRIOVENTRICULAR node, META-analysis, VENTRICULAR ejection fraction, CONFIDENCE intervals, SYSTEMATIC reviews, CATHETER ablation, ATRIAL fibrillation, RANDOMIZED controlled trials, HOSPITAL care, QUALITY of life, QUESTIONNAIRES, HEART failure
Abstract

Background: The prognostic role of catheter ablation of atrial fibrillation (AF) in patients with heart failure (HF) remains uncertain, with guideline recommendations largely based on a single trial. We conducted a meta‐analysis of randomized controlled trials (RCTs) assessing the prognostic impact of AF ablation in patients with HF. Methods: Electronic databases were searched for RCTs comparing 'AF ablation' versus 'other care' (medical therapy and/or atrioventricular node ablation with pacing) in patients with HF. Primary endpoints were ≥1‐year mortality, HF hospitalization and change in left ventricular ejection fraction (LVEF). Meta‐analyses were performed using random‐effects modelling. Results: Nine RCTs (n = 1462) met inclusion criteria. Compared to 'other care', AF ablation significantly reduced ≥1‐year mortality (relative risk [RR] 0.65; 95% confidence intervals [CI], 0.49–0.87) and HF hospitalization (RR 0.64; 95% CI, 0.51–0.81). AF ablation demonstrated significantly greater improvement in LVEF (mean difference [MD] 5.4; 95% CI, 4.4–6.4), 6‐min walk test distance (MD 21.5 meters; 95% CI, 4.6–38.4) and quality of life as measured by Minnesota Living with Heart Failure Questionnaire score (MD 7.2; 95% CI, 2.8–11.7). Meta‐regression analyses showed the beneficial impact of AF ablation on LVEF was significantly blunted by higher prevalence of ischaemic cardiomyopathy. Conclusions: Our meta‐analysis demonstrates AF ablation is superior to 'other care' in improving mortality, HF hospitalization, LVEF and quality of life in patients with HF. However, the highly selected study populations in included RCTs and effect modification mediated by etiology of HF suggests these benefits do not uniformly apply across the HF population. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Systematic review of electrophysiology procedures in patients with obstruction of the inferior vena cava.

Author

Al‐Sinan, Ali, Chan, Kim H., Young, Glenn D., Martin, Andrew, Sepahpour, Ali, and Sy, Raymond W.

Subjects
SYSTEMATIC reviews, ELECTROPHYSIOLOGY, DESCRIPTIVE statistics, VENA cava inferior, ABLATION techniques
Abstract

Aims: The objective of the study was to conduct a systematic review to describe and compare the different approaches for performing cardiac electrophysiology (EP) procedures in patients with interrupted inferior vena cava (IVC) or equivalent entities causing IVC obstruction. Methods: We conducted a structured search to identify manuscripts reporting EP procedures with interrupted IVC or IVC obstruction of any aetiology published up until August 2020. No restrictions were applied in the search strategy. We also included seven local cases that met inclusion criteria. Results: The analysis included 142 patients (mean age 48.9 years; 48% female) undergoing 143 procedures. Obstruction of the IVC was not known before the index procedure in 54% of patients. Congenital interruption of IVC was the most frequent cause (80%); and, associated congenital heart disease (CHD) was observed in 43% of patients in this setting. The superior approach for ablation was the most frequently used strategy (52%), followed by inferior approach via the azygos or hemiazygos vein (24%), transhepatic approach (14%), and retroaortic approach (10%). Electroanatomical mapping (58%), use of long sheaths (41%), intracardiac echocardiography (19%), transesophageal echocardiography (15%) and remote controlled magnetic navigation (13%) were used as adjuncts to aid performance. Ablation was successful in 135 of 140 procedures in which outcomes were reported. Major complications were only reported in patients undergoing AF ablation, including two patients with pericardial effusion, one of whom required surgical repair, and another patient who died after inadvertent entry into an undiagnosed atrioesophageal fistula from a previous procedure. Conclusion: The superior approach is most frequent approach for performing EP procedures in the setting of obstructed IVC. Transhepatic approach is a feasible alternative, and may provide a "familiar approach" for transseptal access when it is required. Adjunctive use of long sheaths, intravascular echocardiography, electro‐anatomical mapping and remote magnetic navigation may be helpful, especially if there is associated complex CHD. With careful planning, EP procedures can usually be successfully performed with a low risk of complications. [ABSTRACT FROM AUTHOR]

Published
2022
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