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Background and objectives: Visceral adiposity is linked to excess morbidity and mortality and positively correlates with the risk of insulin resistance, type-2 diabetes mellitus, cardiovascular disease and premature death. The study was conducted to find out the relationship between visceral adiposity index (VAI) and homeostatic model assessment insulin resistance (HOMA-IR) in diabetes mellitus (DM). Materials and methods: This cross sectional study was carried out on adult population with and without DM. Waist circumference (WC) and body mass index (BMI) were measured. BMI of 25-29.9 kg/m2 and ≥30 kg/m2 was defined as overweight and obese respectively. HOMA-IR method was used to calculate insulin resistance (IR). Standard formula using BMI, WC, triglyceride (TG) and high density lipoprotein cholesterol (HDL-c) was used to calculate VAI. Blood was analyzed for fasting blood glucose (FBS), TG, HDL-c and insulin level. Results: A total of 439 individuals were included in the study of which 269 had DM and 170 were healthy volunteers and the mean age was 41.47±6.82 and 36.16±7.44 years respectively. Compared to healthy controls, a greater number of diabetics had high VAI (86.5% vs. 98.9%) and high IR (43.5% vs. 85.1%). We found the highest sensitivity and specificity at a cut-off of 2.23 of VAI while at 3.65 had the highest specificity. Insulin resistance was observed significantly higher in those with diabetes compared to control, both in case of normal and high VAI at all cut-offs of VAI. Among anthropometric parameters (WC, BMI and VAI), VAI had positive (r=0.21, p

Restoration of a fractured tooth is routinely performed in clinical practice. Many factors are considered in an effort to provide optimal mechanical properties, aesthetics, longevity as well as patient acceptance. In this type of challenging endeavour, main effort should be made to save as much of the coronal tooth structure to increase survival rate of endodontically-treated teeth. This case report presents a 35-year-old male with an oblique complicated crown fracture of maxillary left central incisor tooth. The procedure used to repair the fracture was gingivectomy followed by endodontic treatment. The root canal was filled with a root canal sealer and gutta-percha points. After root canal obturation, the tooth was restored with a glass fiber post and composite resin without additional crown coverage. The restoration made it possible to maintain the remaining tooth structure in a good occlusion and resulted in a high level of patient satisfaction.

The purpose of this study was to compare the frequency and nature of pain between the vital inflamed (n=55) and non-vital (n=55) teeth that received single visit root canal treatment. The frequency and nature of pain were assessed as no pain, mild, moderate and severe pain on day 2 and day 7. The results showed that 76.4 and 85.5% participants felt no pain in vital inflamed teeth on day 2 and day 7, respectively. On the other hand, 63.6 and 74.5% participants felt no pain in non-vital teeth on day 2 and day 7, respectively. The remaining participants only felt mild to moderate pain. There were no significant difference between the two groups (p=0.435 on day 2 and p=0.371 on day 7). The results suggested that single visit root canal treatment is equally effective in both vital inflamed and non-vital teeth.

A 14 year old boy, came to the Department with the complaint of accidental missing of upper two central incisor teeth (Figure 1A, B). The teeth were brought by the patient those were healthy and intact. His medical history was non-contributory and he was tetanus immunized. He came 2 hours after the accident with the missing teeth immersed into 0.9% sodium chloride solution. On clinical examination, there were missing of both central incisors. Sockets were full of blood. On palpation, no other tooth was tender.

In the present study, the ability of mineral trioxide aggregate in the formation of apical plug for healing of large periapical lesion with open apex was assessed and evaluated the clinical outcome. Fifteen participants with periapical lesion at the upper anterior teeth with open apex were treated with mineral trioxide aggregate. The effect on healing of apical size was evaluated at 3, 6, and 12 months by radiological examinations in the form of periapical index criteria, diameter of the lesion size and the presence or absence of apical tissue barrier. The results found that neither pain nor any sinus was detected at 12 months. The mean size of the apical lesion was gradually reduced from 5.1 × 3.8 to 1.5 × 0.9 mm and mean PAI was reduced from 3.3 to 1.7 mm. The differences between mean size of periapical lesion at preoperative and 12 months observation period was also statistically significant (p

A 28 year old male patient came to the outpatient Department complain-ing of discomfort on his lower right first molar tooth during mastication for one month. The patient also stated that he had received dental treatment on the lower right side three months back. Clinically, the tooth appeared sound but there was poor coronal filling of the affected tooth and the pocket depth was within normal range (Figure 1A,B). When the pulp vitality test was performed, it responded negatively. However, percussion pain was present. It seems that due to iatrogenic mishaps, chronic periodontitis could be developed in this case.

The purpose of the present study was to assess the giomer retention following application of one step self etch adhesive and one-step self-etch adhesive plus an extra hydrophobic adhesive layer in non-carious cervical lesion. Twenty four participants having bilateral cervical lesion at the maxillary premolars teeth were selected. Following cleaning of the cervical lesions, 24 left premolar teeth were restored with giomer by using the one-step self-etch system (Group A) and 24 right premolar teeth were restored with giomer by using one-step self-etching plus extra hydrophobic adhesive layer (Group B). Participants were recalled at 6 and 15 months for evaluating the clinical outcome. The results showed that at 15 months, 18 giomer restorations in Group A and 21 in Group B were intact inside the cavity and no significant difference was found between the two groups. It can be concluded that giomer restoration used with one-step self- etching plus additional adhesive layer slightly improved the retention of the material.

Different devices and techniques have been developed to retrieve fractured instruments during the endodontic procedures. This case report describes the management of a broken instrument, which was accidentally broken during cleaning and shaping of the root canal in right 2nd molar tooth. A # 25 stainless steel K-file was separated in mesiobuccal canal of the treated tooth. At first, a radiograph was taken to confirm the level of separation of the instrument. The instrument was found to be separated at the apical 3rd of the mesial canal and then file bypass technique was performed. Calcium hydroxide dressing was given for 7 days followed by obturation with guttapercha cone and zinc oxide eugenol sealer in lateral condensation technique. It can be concluded that bypass technique can be considered as simple and effective technique for the management of broken instrument into the root canal.

A simple and efficient approach for the S‐arylation of tetrazole‐5‐thiol using copper oxide nanoparticles has been developed. Recently, heterocyclic thiols have attracted a great deal of interest due to their diverse biological and pharmacological properties. Thus, great efforts have been devoted in introducing efficient protocols for the synthesis of such compounds. The utilization of copper oxide nanoparticles has been substantially chosen for catalysis due to their low cost, high surface area, sustainability, and reusability. The distinctive features of this methodology involve a ligand‐free catalytic system, simple reaction procedure, shorter reaction time, wide substrate scope compatibility, and high yield of the products. [ABSTRACT FROM AUTHOR]

Neem oil, a natural antibacterial agent from neem tree ( Azadarichtaindica ) has been used to impart antibacterial activity to polyester fabrics. Solvent induced polymer modification method was used and that facilitated the easy entry of neem molecules into the compact structure of polyethylene terephthalate (PET) polyester. The polyester fabric was treated with trichloroacetic acid-methylene chloride (TCAMC) solvent system at room temperature prior to treatment with neem oil. The concentration of TCAMC and the treatment time were optimised. XRD and SEM results showed that the TCAMC treatment causes polymer modification and morphological changes in the PET polyester. Antibacterial activity of TCAMC pre-treated and neem-oil-treated polyester fabric was tested using AATCC qualitative and quantitative methods. Both Gram-positive and Gram-negative organisms were used to determine the antimicrobial activity. It was observed that the treated fabric registers substantial antimicrobial activity against both the Staphylococcus aureus (Gram-positive) and the Escherichia coli (Gram-negative) and the effect increases with the increase in concentration of TCAMC treatment. The antibacterial effect remains substantial even after 25 launderings. A kinetic growth study involving the effect of antibacterial activity at various incubation times was carried out. [ABSTRACT FROM AUTHOR]

The bactericidal action of silver nanoparticles has been observed by many researchers since few years. In this study, we have developed an antibacterial ceramics (ACs) by absorbing synthesized silver nanoparticles within the ceramic matrix developed by us from an abundantly available coal fly ash, an extremely hazardous by-product of thermal power plants. Nanoparticles dispersions of different particle sizes were made absorbed in to the ceramic matrix to evaluate its bactericidal activity against both Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative) bacteria, taken as the model microorganisms. This study showed that the total bactericidal action of ACs depends on the size of absorbed nanoparticles and the content of nanoparticles in the dispersions within the ceramic matrix. ACs thus developed release very slowly a minute amount of nanoparticles and show strong and prolonged bactericidal activity against pathogenic strain of both types of bacteria. The concentration of prepared nanoparticles in dispersion and the concentration of released nanoparticles in aqueous medium from the absorbed ceramic matrix were measured using inductively coupled plasma spectrophotometer. The mechanism of the antibacterial action was also studied using transmission electron microscopy image analysis of the bacterial cross-section of both types of bacteria. [ABSTRACT FROM AUTHOR]

Abstract: The increasing accumulation of fly ash from thermal power plants poses a major problem to the environment. The present work reflects the novel utilization of this profusely available industrial waste in the form of an antibacterial hard ceramic material by treating fly ash with ferric oxide (Fe2O3) and titania (TiO2) during sintering process at 1600°C. The developed material shows more than 90% bacterial reduction against both Gram-positive and Gram-negative bacteria. The mechanism of their antibacterial action was studied by transmission electron microscopy (TEM) image analysis of the bacterial cross-section. The developed ceramic material acquires hardness due to the enhancement of the natural mullite content in the matrix. The mullite content and the crystallinity of mullite have shown their increasing trend with increasing concentration of the metal oxide during sintering process. A maximum of ~37% increase in mullite was obtained for 7% w/w Fe2O3 and TiO2. Metal oxide lowered the activation energy of the reaction and enhanced the reaction rate of alumina (Al2O3)–silica (SiO2) to form mullite which increases the hardness. The study highlights novel utilization of fly ash as a hard ceramic antibacterial product (bioceramics) for both structural and hygiene applications in an eco-friendly way. [Copyright &y& Elsevier]

Nowadays the increased generation of fly ash from thermal power plants is a major concern to our society due to its harmful impact on environment. To utilize this waste in a useful way, we have developed a novel ceramic material which was produced by treating fly ash with bauxite during sintering process. The developed ceramic material acquired increased hardness because of enhanced mullite content during the process with an additional property of reducing pathogenic bacterial growth by more than 90%. The mechanism of their antibacterial action was studied by TEM image analysis of the bacterial cross section. Mullite content and the crystallinity of mullite have increased with increasing concentration of bauxite during sintering process. A maximum of ~ 31% increase in mullite phase was obtained for 50% w/w bauxite and thus increased the hardness which was measured by LEICA Vickers hardness tester. The structural composition of the developed ceramics materials and the surface texture were evaluated by FTIR studies and FESEM micrographs, respectively. This work highlights a sustainable approach of using fly ash in developing antimicrobial ceramics in an eco-friendly way having a vast potential to be used in the bacteria prone area like hospitals. [ABSTRACT FROM AUTHOR]

Aim: Temporomandibular joint ankylosis (TMJA) management involves many surgical treatment modalities depending on the experience of the operator. A lot of literature has been published on various treatment modalities. Many systematic reviews (SRs) were published without any published prior protocol. So, the study aimed to evaluate the quality of SRs with meta-analysis of TMJA management., Materials and Methods: Systematic reviews with meta-analysis were included for the quality assessment using AMSTAR (assessment of multiple SRs) and Glenny et al. checklist by two independent teams. The search was limited to the Medline database archival (from January 1980 to December 2018)., Results: The primary search identified 1,507 related articles. After activation of different filters, abstracts screening, and cross-referencing, finally, a total of six studies were assessed to make the overview up-to-date., Conclusion: The articles scored 8 to 11 with AMSTAR and 7 to 13 with the Glenny et al. checklist. None of the published reviews received maximum scores. The methodology and heterogeneity are essential factors to assess the quality of the published literature., Clinical Significance: None of the included meta-analysis was registered or published protocol with Prospero or Cochrane before publication for better validity of the studies. The authors are advised to follow reporting criteria so that in the future it is possible to provide the standards of care for TMJA with the highest quality of evidence.