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The field of rehabilitation has undergone major change, shifting toward an emphasis on health outcomes and understanding multiple determinants of health. Person-centered care and evidence-based medicine have become central considerations, and rehabilitation psychologists are at the forefront of this modern, whole-person approach. The handbook has been significantly updated to reflect these new developments. Chapters address several core topics, such as education and training in rehabilitation psychology, competency-based practice, and fluctuating health policy. Additional chapters cover the assessment and treatment of specific health conditions, including chronic pain, acquired disability, spinal cord injury, traumatic brain injury, and amputation. This edition also includes information about artificial intelligence, virtual reality, public health, community rehabilitation, and other innovations in health care. Contributors are not only visionaries in the rehabilitation field but also expert practitioners in key areas. They integrate their experience with empirical research, highlight methodological advances, recommend best practices, discuss policy implications, and identify possibilities for the future. Both experienced clinicians and early-career practitioners will find this book an invaluable resource for delivering effective behavioral health care to people with chronic health conditions.