14 results on '"Spinelli, Marta"'
Search Results
2. 21 cm intensity mapping cross-correlation with galaxy surveys: Current and forecasted cosmological parameters estimation for the SKAO.
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Berti, Maria, Spinelli, Marta, and Viel, Matteo
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PARAMETER estimation , *COSMIC background radiation , *MARKOV chain Monte Carlo , *LARGE scale structure (Astronomy) , *N-body simulations (Astronomy) , *GALAXY clusters - Abstract
We present a comprehensive set of forecasts for the cross-correlation signal between 21 cm intensity mapping and galaxy redshift surveys. We focus on the data sets that will be provided by the SKAO for the 21 cm signal, DESI and Euclid for galaxy clustering. We build a likelihood which takes into account the effect of the beam for the radio observations, the Alcock–Paczynski effect, a simple parametrization of astrophysical nuisances, and fully exploit the tomographic power of such observations in the range z = 0.7–1.8 at linear and mildly non-linear scales (k < 0.25 h Mpc−1). The forecasted constraints, obtained with Monte Carlo Markov Chains techniques in a Bayesian framework, in terms of the six base parameters of the standard ΛCDM model, are promising. The predicted signal-to-noise ratio for the cross-correlation can reach ∼50 for z ∼ 1 and k ∼ 0.1 h Mpc−1. When the cross-correlation signal is combined with current Cosmic Microwave Background (CMB) data from Planck, the error bar on |$\Omega _{\rm c}\, h^2$| and H 0 is reduced by factors 3 and 6, respectively, compared to CMB only data, due to the measurement of matter clustering provided by the two observables. The cross-correlation signal has a constraining power that is comparable to the autocorrelation one and combining all the clustering measurements a sub-per cent error bar of 0.33 per cent on H 0 can be achieved, which is about a factor 2 better than CMB only measurements. Finally, as a proof of concept, we test the full pipeline on the real data measured by the MeerKat collaboration (Cunnington et al. 2022) presenting some (weak) constraints on cosmological parameters. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Paget disease of the vulva an analysis of 24 cases
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Loiacono, Rosalia Maria Rita, Traversi, Paola, Deliso, Maria Assunta, Gargano, Giulio, Kardhashi, Anila, Francescato, Roberta, Loizzi, Vera, Spinelli, Marta, Lovascio, Serena, Fiorito, Maura, Resta, Leonardo, Popescu, Ondina, Cicinelli, Ettore, and Cormio, Gennaro
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- 2019
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4. The foreground transfer function for H I intensity mapping signal reconstruction: MeerKLASS and precision cosmology applications
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Cunnington, Steven, Wolz, Laura, Bull, Philip, Carucci, Isabella P., Grainge, Keith, Irfan, Melis O., Li, Yichao, Pourtsidou, Alkistis, Santos, Mario G., Spinelli, Marta, and Wang, Jingying
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data analysis ,methods: statistical ,cosmology: observations ,radio lines: general [large-scale structure of Universe ,methods] ,large-scale structure of Universe ,radio lines: general ,methods: data analysis - Abstract
Blind cleaning methods are currently the preferred strategy for handling foreground contamination in single-dish H I intensity mapping surveys. Despite the increasing sophistication of blind techniques, some signal loss will be inevitable across all scales. Constructing a corrective transfer function using mock signal injection into the contaminated data has been a practice relied on for H I intensity mapping experiments. However, assessing whether this approach is viable for future intensity mapping surveys, where precision cosmology is the aim, remains unexplored. In this work, using simulations, we validate for the first time the use of a foreground transfer function to reconstruct power spectra of foreground-cleaned low-redshift intensity maps and look to expose any limitations. We reveal that even when aggressive foreground cleaning is required, which causes >50 per cent negative bias on the largest scales, the power spectrum can be reconstructed using a transfer function to within sub-per cent accuracy. We specifically outline the recipe for constructing an unbiased transfer function, highlighting the pitfalls if one deviates from this recipe, and also correctly identify how a transfer function should be applied in an autocorrelation power spectrum. We validate a method that utilizes the transfer function variance for error estimation in foreground-cleaned power spectra. Finally, we demonstrate how incorrect fiducial parameter assumptions (up to ±100 per cent bias) in the generation of mocks, used in the construction of the transfer function, do not significantly bias signal reconstruction or parameter inference (inducing, Monthly Notices of the Royal Astronomical Society, 523 (2), ISSN:0035-8711, ISSN:1365-2966, ISSN:1365-8711
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- 2023
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5. Multipole expansion for 21 cm intensity mapping power spectrum: Forecasted cosmological parameters estimation for the SKA observatory.
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Berti, Maria, Spinelli, Marta, and Viel, Matteo
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POWER spectra , *MONTE Carlo method , *MARKOV chain Monte Carlo , *PARAMETER estimation , *OBSERVATORIES - Abstract
The measurement of the large-scale distribution of neutral hydrogen in the late Universe, obtained with radio telescopes through the hydrogen 21 cm line emission, has the potential to become a key cosmological probe in the upcoming years. We explore the constraining power of 21 cm intensity mapping observations on the full set of cosmological parameters that describe the ΛCDM model. We assume a single-dish survey for the SKA Observatory and simulate the 21 cm linear power spectrum monopole and quadrupole within six redshift bins in the range |$z$| = 0.25–3. Forecasted constraints are computed numerically through Markov Chain Monte Carlo techniques. We extend the sampler CosmoMC by implementing the likelihood function for the 21 cm power spectrum multipoles. We assess the constraining power of the mock data set alone and combined with Planck 2018 CMB observations. We find that 21 cm multipoles observations alone are enough to obtain constraints on the cosmological parameters comparable with other probes. Combining the 21 cm data set with CMB observations results in significantly reduced errors on all the cosmological parameters. The strongest effect is on Ω c h 2 and H 0, for which the error is reduced by almost a factor four. The percentage errors we estimate are |$\sigma _{\Omega _ch^2} = 0.25~{{\ \rm per\ cent}}$| and |$\sigma _{H_0} = 0.16~{{\ \rm per\ cent}}$| , to be compared with the Planck only results |$\sigma _{\Omega _ch^2} = 0.99~{{\ \rm per\ cent}}$| and |$\sigma _{H_0} = 0.79~{{\ \rm per\ cent}}$|. We conclude that 21 cm SKAO observations will provide a competitive cosmological probe, complementary to CMB and, thus, pivotal for gaining statistical significance on the cosmological parameters constraints, allowing a stress test for the current cosmological model. [ABSTRACT FROM AUTHOR]
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- 2023
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6. H i intensity mapping with MeerKAT: power spectrum detection in cross-correlation with WiggleZ galaxies.
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Cunnington, Steven, Li, Yichao, Santos, Mario G, Wang, Jingying, Carucci, Isabella P, Irfan, Melis O, Pourtsidou, Alkistis, Spinelli, Marta, Wolz, Laura, Soares, Paula S, Blake, Chris, Bull, Philip, Engelbrecht, Brandon, Fonseca, José, Grainge, Keith, and Ma, Yin-Zhe
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POWER spectra ,PHYSICAL cosmology ,MEERKAT ,DARK energy ,GALAXIES ,GALAXY clusters ,GALAXY spectra - Abstract
We present a detection of correlated clustering between MeerKAT radio intensity maps and galaxies from the WiggleZ Dark Energy Survey. We find a 7.7σ detection of the cross-correlation power spectrum, the amplitude of which is proportional to the product of the |${\rm H}\, {\small I}$| density fraction (|$\Omega _{{\rm H}\, {\small I}}$|), |${\rm H}\, {\small I}$| bias (|$b_{{\rm H}\, {\small I}}$|), and the cross-correlation coefficient (r). We therefore obtain the constraint |$\Omega _{{\rm H}\, {\small I}}b_{{\rm H}\, {\small I}}r\, {=}\, [0.86\, {\pm }\, 0.10\, ({\rm stat})\, {\pm }\, 0.12\, ({\rm sys})]\, {\times }\, 10^{-3}$| , at an effective scale of |$k_{\rm eff}\ {\sim }\ 0.13\, h\, \text{Mpc}^{-1}$|. The intensity maps were obtained from a pilot survey with the MeerKAT telescope, a 64-dish pathfinder array to the SKA Observatory (SKAO). The data were collected from 10.5 h of observations using MeerKAT 's L -band receivers over six nights covering the 11 h field of WiggleZ, in the frequency range 1015–973 MHz (0.400 |$\, {\lt }\, z\, {\lt }\,$| 0.459 in redshift). This detection is the first practical demonstration of the multidish autocorrelation intensity mapping technique for cosmology. This marks an important milestone in the roadmap for the cosmology science case with the full SKAO. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Gravitational waves Ă— HI intensity mapping: cosmological and astrophysical applications.
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Scelfo, Giulio, Spinelli, Marta, Raccanelli, Alvise, Boco, Lumen, Lapi, Andrea, and Viel, Matteo
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- 2022
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8. H i intensity mapping with MeerKAT: primary beam effects on foreground cleaning.
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Matshawule, Siyambonga D, Spinelli, Marta, Santos, Mario G, and Ngobese, Sibonelo
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MEERKAT , *GAUSSIAN beams , *K-spaces , *SIGNAL reconstruction , *LARGE scale structure (Astronomy) - Abstract
Upcoming and future neutral hydrogen Intensity Mapping surveys offer a great opportunity to constrain cosmology in the post-reionization Universe, provided a good accuracy is achieved in the separation between the strong foregrounds and the cosmological signal. Cleaning methods are often applied under the assumption of a simplistic Gaussian primary beam. In this work, we test the cleaning in the presence of a realistic primary beam model with a non-trivial frequency dependence. We focus on the Square Kilometre Array precursor MeerKAT telescope and simulate a single-dish wide-area survey. We consider the main foreground components, including an accurate full-sky point source catalogue. We find that the coupling between beam sidelobes and the foreground structure can complicate the cleaning. However, when the beam frequency dependence is smooth, we show that the cleaning is only problematic if the far sidelobes are unexpectedly large. Even in that case, a proper reconstruction is possible if the strongest point sources are removed and the cleaning is more aggressive. We then consider a non-trivial frequency dependence: a sinusoidal type feature in the beamwidth that is present in the MeerKAT beam and is expected in most dishes, including SKA1-MID. Such a feature, coupling with the foreground emission, biases the reconstruction of the signal across frequency, potentially impacting the cosmological analysis. We show that this effect is constrained to a narrow region in k ∥ space and can be reduced if the maps are carefully re-smoothed to a common lower resolution. [ABSTRACT FROM AUTHOR]
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- 2021
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9. H i intensity mapping with MeerKAT: calibration pipeline for multidish autocorrelation observations.
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Wang, Jingying, Santos, Mario G, Bull, Philip, Grainge, Keith, Cunnington, Steven, Fonseca, José, Irfan, Melis O, Li, Yichao, Pourtsidou, Alkistis, Soares, Paula S, Spinelli, Marta, Bernardi, Gianni, and Engelbrecht, Brandon
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RADIO interference ,MEERKAT ,THERMAL noise ,RADIO galaxies ,CALIBRATION - Abstract
While most purpose-built 21-cm intensity mapping experiments are close-packed interferometer arrays, general-purpose dish arrays should also be capable of measuring the cosmological 21-cm signal. This can be achieved most efficiently if the array is used as a collection of scanning autocorrelation dishes rather than as an interferometer. As a first step towards demonstrating the feasibility of this observing strategy, we show that we are able to successfully calibrate dual-polarization autocorrelation data from 64 MeerKAT dishes in the L band (856–1712 MHz, 4096 channels), with 10.5 h of data retained from six nights of observing. We describe our calibration pipeline, which is based on multilevel radio frequency interference flagging, periodic noise diode injection to stabilize gain drifts, and an absolute calibration based on a multicomponent sky model. We show that it is sufficiently accurate to recover maps of diffuse celestial emission and point sources over a 10° × 30° patch of the sky overlapping with the WiggleZ 11-h field. The reconstructed maps have a good level of consistency between per-dish maps and external data sets, with the estimated thermal noise limited to 1.4 × the theoretical noise level (∼2 mK). The residual maps have rms amplitudes below 0.1 K, corresponding to |$\lt 1{{\ \rm per\ cent}}$| of the model temperature. The reconstructed Galactic H i intensity map shows excellent agreement with the Effelsberg–Bonn H i Survey, and the flux of the radio galaxy 4C + 03.18 is recovered to within 3.6 per cent, which demonstrates that the autocorrelation can be successfully calibrated to give the zero-spacing flux and potentially help in the imaging of MeerKAT interferometric data. Our results provide a positive indication towards the feasibility of using MeerKAT and the future Square Kilometre Array to measure the H i intensity mapping signal and probe cosmology on degree scales and above. [ABSTRACT FROM AUTHOR]
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- 2021
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10. Extracting H i astrophysics from interferometric intensity mapping.
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Chen, Zhaoting, Wolz, Laura, Spinelli, Marta, and Murray, Steven G
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ASTROPHYSICS ,GALAXY formation ,POWER spectra ,REDSHIFT ,LARGE scale structure (Astronomy) - Abstract
We present a new halo model of neutral hydrogen (H i) calibrated to galaxy formation simulations at redshifts z ∼ 0.1 and z ∼ 1.0 that we employ to investigate the constraining power of interferometric H i intensity mapping on H i astrophysics. We demonstrate that constraints on the small-scale H i power spectrum can break the degeneracy between the H i density |$\Omega _{\rm H\, \small {I}}$| and the H i bias |$b_{\rm H\, \small {I}}$|. For z ∼ 0.1, we forecast that an accurate measurement of |$\Omega _{\rm H\, \small {I}}$| up to 6 per cent level precision and the large-scale H i bias |$b_{\rm H\, \small {I}}^0$| up to 1 per cent level precision can be achieved using Square Kilometre Array (SKA) pathfinder data from MeerKAT and Australian SKA Pathfinder (ASKAP). We also propose a new description of the H i shot noise in the halo model framework in which a scatter of the relation between the H i mass of galaxies and their host halo mass is taken into account. Furthermore, given the number density of H i galaxies above a certain H i mass threshold, future surveys will also be able to constrain the H i mass function using only the H i shot noise. This will lead to constraints at the 10 per cent level using the standard Schechter function. This technique will potentially provide a new way of measuring the H i mass function, independent from existing methods. We predict that the SKA will be able to further improve the low-redshift constraints by a factor of 3, as well as pioneering measurements of H i astrophysics at higher redshifts. [ABSTRACT FROM AUTHOR]
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- 2021
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11. The atomic hydrogen content of the post-reionization Universe.
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Spinelli, Marta, Zoldan, Anna, De Lucia, Gabriella, Xie, Lizhi, and Viel, Matteo
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ATOMIC hydrogen , *GALAXY formation , *DARK matter , *RADIO telescopes , *GALACTIC evolution ,UNIVERSE - Abstract
We present a comprehensive analysis of atomic hydrogen (H i) properties using a semi-analytical model of galaxy formation and N -body simulations covering a large cosmological volume at high resolution. We examine the H i mass function and the H i density, characterizing both their redshift evolution and their dependence on hosting halo mass. We analyse the H i content of dark matter haloes in the local Universe and up to redshift z = 5, discussing the contribution of different galaxy properties. We find that different assembly history plays a crucial role in the scatter of this relation. We propose new fitting functions useful for constructing mock H i maps with halo occupation distribution techniques. We investigate the H i clustering properties relevant for future 21 cm intensity mapping (IM) experiments, including the H i bias and the shot-noise level. The H i bias increases with redshift and it is roughly flat on the largest scales probed. The scale dependence is found at progressively larger scales with increasing redshift, apart from a dip feature at z = 0. The shot-noise values are consistent with the ones inferred by independent studies, confirming that shot noise will not be a limiting factor for IM experiments. We detail the contribution from various galaxy properties on the H i power spectrum and their relation to the halo bias. We find that H i poor satellite galaxies play an important role at the scales of the one-halo term. Finally, we present the 21 cm signal in redshift space, a fundamental prediction to be tested against data from future radio telescopes such as Square Kilometre Array. [ABSTRACT FROM AUTHOR]
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- 2020
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12. Cosmological parameter estimation with the Planck satellite data : from the construction of a likelihood to neutrino properties
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Spinelli, Marta, Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Paris Sud - Paris XI, and Stéphane Plaszczynski
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LCDM model ,[SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,Neutrino ,Cosmic Microwave Background ,Likelihood ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Markov Chain Monte Carlo ,Méthode de Monte-Carlo par chaînes de Markov ,Modèle LCDM ,Fond diffus cosmologique ,Fonction de vraisemblance - Abstract
The cosmic microwave background (CMB), relic of the hot Big-Bang, carries the traces of both the rich structure formation of the late time epochs and the energetic early phases of the universe.The Planck satellite provided, from 2009 to 2013, high-quality measurements of the anisotropies of the CMB. These are used in this thesis to determine the parameters of the standard cosmological model and of the extension concerning the neutrino sector. The construction of an high-l Planck likelihood is detailed. This involves a masking strategy that deals in particular with the contamination from thermal emission of the Galaxy. The residual foregrounds are treated directly at the power spectrum level relying on physically motivated templates based on Planck studies.The statistical methods needed to extract the cosmological parameters in the comparison between models and data are described, both the Bayesian Monte Carlo Markov Chain techniques and the frequentist profile likelihood. Results on cosmological parameters are presented using Planck data alone and in combination with the small scale data from the ground based CMB experiment ACT and SPT, the Baryon Acoustic Oscillation and the Supernovae. Constraints on the absolute scale of neutrino masses and of the number of effective neutrino are also discussed.; Le fond diffus cosmologique (CMB), relique du Big-Bang chaud, porte les traces à la fois de la formation des structures des époques récentes et des premières phases énergétiques de l'Univers.Le satellite Planck, en service de 2009 à 2013, a fourni des mesures de haute qualité des anisotropies du CMB. Celles-ci sont utilisés dans cette thèse pour déterminer les paramètres du modèle cosmologique standard et autour du secteur des neutrinos.Ce travail décrit la construction d'un fonction de vraisemblance pour les hauts-l de Planck. Cela implique une stratégie de masquage pour l'émission thermique de la Galaxie ainsi que pour les sources ponctuelles. Les avant-plans résiduels sont traités directement au niveau du spectre de puissance en utilisant des templates physiques bases sur des études de Planck.Les méthodes statistiques nécessaires pour extraire les paramètres cosmologiques dans la comparaison entre les modèles et les données sont décrites, à la fois la méthode bayésienne de Monte-Carlo par chaînes de Markov et la technique fréquentiste du profil de la fonction de vraisemblance.Les résultats sur les paramètres cosmologiques sont présentés en utilisant les données de Planck seul et en combinaison avec les données à petites échelles des expériences de CMB basées au sol (ACT et SPT), avec les contraintes provenant des mesures des oscillations acoustiques des baryons (BAO) et des supernovae. Les contraintes sur l'échelle absolue de la masse des neutrinos et sur le nombre effectif de neutrinos sont également discutées.
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- 2015
13. On the contamination of the global 21-cm signal from polarized foregrounds.
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Spinelli, Marta, Bernardi, Gianni, and Santos, Mario G
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POLARIZATION (Nuclear physics) , *INTERSTELLAR medium , *GALACTIC magnetic fields , *COSMIC background radiation - Abstract
Global (i.e. sky-averaged) 21-cm signal experiments can measure the evolution of the Universe from the cosmic dawn to the epoch of reionization (EoR). These measurements are challenged by the presence of bright foreground emission that can be separated from the cosmological signal if its spectrum is smooth. This assumption fails in the case of single-polarization antennas as they measure linearly polarized foreground emission – which is inevitably Faraday rotated through the interstellar medium. We investigate the impact of Galactic polarized foregrounds on the extraction of the global 21-cm signal through realistic sky and dipole simulations both in a low-frequency band from 50 to 100 MHz, where a 21-cm absorption profile is expected, and in a higher frequency band (100–200 MHz). We find that the presence of a polarized contaminant with complex frequency structure can bias the amplitude and the shape of the reconstructed signal parameters in both bands. We investigate if polarized foregrounds can explain the unexpected 21-cm cosmic dawn signal recently reported by the Experiment to Detect the Global EoR Signature (EDGES) Collaboration. We find that unaccounted polarized foreground contamination can produce an enhanced and distorted 21-cm absorption trough similar to the anomalous profile reported by Bowman et al. and whose amplitude is in mild tension with the assumed input Gaussian profile (at ∼1.5σ level). Moreover, we note that, under the hypothesis of contamination from polarized foreground, the amplitude of the reconstructed EDGES signal can be overestimated by around |$30\, {\rm per\, cent}$| , mitigating the requirement for an explanation based on exotic physics. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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14. Gender, age, geographical area, food neophobia and their relationships with the adherence to the mediterranean diet: New insights from a large population cross-sectional study
- Author
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Fiorella Sinesio, Isabella Endrizzi, Caterina Dinnella, Erminio Monteleone, Nicola Condelli, Giulia Maria Daniele, Rossella Di Monaco, Sara Spinelli, Flavia Gasperi, Marta Cianciabella, Paola Vitaglione, Stefano Predieri, Alessandra Bendini, Camilla Cattaneo, Ella Pagliarini, Tullia Gallina Toschi, Monica Laureati, Luisa Torri, Stefano Predieri, Fiorella Sinesio, Erminio Monteleone, Sara Spinelli, Marta Cianciabella, Giulia M. Daniele, Caterina Dinnella, Flavia Gasperi, Isabella Endrizzi, Luisa Torri, Tullia Gallina Toschi, Alessandra Bendini, Ella Pagliarini, Camilla Cattaneo, Rossella Di Monaco, Paola Vitaglione, Nicola Condelli, Monica Laureati, Predieri, S., Sinesio, F., Monteleone, E., Spinelli, S., Cianciabella, M., Daniele, G. M., Dinnella, C., Gasperi, F., Endrizzi, I., Torri, L., Toschi, T. G., Bendini, A., Pagliarini, E., Cattaneo, C., Di Monaco, R., Vitaglione, P., Condelli, N., and Laureati, M.
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Male ,0301 basic medicine ,Mediterranean diet ,Cross-sectional study ,Food rejection ,Health benefits ,Diet, Mediterranean ,0302 clinical medicine ,Vegetables ,Avoidant Restrictive Food Intake Disorder ,Nutrition and Dietetics ,food rejection ,Neophobia ,digestive, oral, and skin physiology ,Age Factors ,Fishes ,Mediterranean eating pattern ,diet quality ,Middle Aged ,healthy eating ,Italy ,Cohort ,Healthy eating ,Anxiety ,Female ,medicine.symptom ,lcsh:Nutrition. Foods and food supply ,Diet quality ,Adult ,socio-demographics ,Adolescent ,Large population ,lcsh:TX341-641 ,030209 endocrinology & metabolism ,Environment ,Affect (psychology) ,Article ,Young Adult ,03 medical and health sciences ,Sex Factors ,medicine ,Animals ,Humans ,sociodemographics ,030109 nutrition & dietetics ,business.industry ,Sociodemographics ,Feeding Behavior ,medicine.disease ,Cross-Sectional Studies ,Settore AGR/15 - SCIENZE E TECNOLOGIE ALIMENTARI ,Fruit ,Patient Compliance ,business ,Food Science ,Demography - Abstract
The Mediterranean diet (MD) is associated with many health benefits. The association between the MD and food neophobia (FN) is still unexplored in adults. The present cross-sectional study was aimed to explore the relationships between adherence to the MD, FN, and sociodemographic variables in a large Italian cohort. Familiarity and frequency use (FFI) of prototypical and non-prototypical Mediterranean foods were used to calculate a new adherence index: the Italian Taste Mediterranean Index (ITMI). The FFI of all Mediterranean foods increased with age, while butter, soft drinks, red/cured meat, and sweets were more common in younger people. Accordingly, ITMI increased with age (F2,2384 = 54.11, p <, 0.0001). Women recorded a higher ITMI (6.70) than men (6.10). Individuals with high FN showed higher FFI for soft drinks and sweets and lower ones for most typical MD foods, than individuals with low FNs. A decrease of ITMI was recorded with the increase of the FN(F2,2384 = 22.84, 0.0001). With ageing, ITMI increased even in individuals with a high FN. The results suggest that FN may negatively affect adherence to the MD, lowering its potential health benefits, in the adult population. Monitoring of food habits, dietary education, and anxiety management, may be valuable tools to control FN and support the adherence to the MD.
- Published
- 2020
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