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119 results on '"Spiazzi, L."'

8. A randomized split-face clinical trial of conventional vs indoor-daylight photodynamic therapy for the treatment of multiple actinic keratosis of the face and scalp and photoaging.

Author

Arisi, M., Rossi, M. T., Spiazzi, L., Guasco Pisani, E., Venturuzzo, A., Rovati, C., Tomasi, C., Venturini, M., and Calzavara-Pinton, P. G.

Subjects
ACTINIC keratosis, PHOTODYNAMIC therapy, CLINICAL trials, SCALP, LED lamps, TREATMENT effectiveness
Abstract

Recently, indoor daylight photodynamic therapy (idl-PDT) has been developed; however, its efficacy and tolerability remain to be assessed. This is a not-inferiority study to compare treatment outcomes of cPDT with a red LED lamp and idlPDT with a polychromatic white LED lamp in adult patients affected by symmetrical AKs of face and/or scalp. In this comparative, intra-patient, split-face, randomized clinical trial forty-three adult patients were enrolled. Two contralateral and symmetrical target areas of the face and/or scalp harboring at least 5 AKs were selected and randomized 1:1 to treatment with cPDT and idlPDT. The AKs number and cumulative area were assessed at baseline (T0). Efficacy and cosmetic outcome were assessed 3 months after treatment (T1). Total AKs number and area reduced significantly with both idlPDT (p <.0001) and cPDT (p <.0001) in comparison to baseline. cPDT was more painful (p <.0001) and induced a more severe inflammation (p <.0001). Twenty-nine patients (70.7%) gave their overall preference to idlPDT (p <.001). idlPDT may represent an alternative treatment protocol to cPDT for in-office treatment of AKs patients with better tolerability and a not inferior efficacy. [ABSTRACT FROM AUTHOR]

Published
2022
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16. Intensity Modulated Proton Therapy (IMPT) vs Intensity Modulated Radiation Therapy (IMRT)in malignant pleural mesothelioma (MPM): a dosimetric comparison

Author

Lorentini, S, Hamer, P, Amichetti, M, Spiazzi, L, Tonoli, S, Magrini, S, and Schwarz, M

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Background: Recently the trimodality approach (neoadjuvant chemotherapy, extrapleural pneumonectomy and hemithoracic irradiation) is increasingly used for patients (pts) affected by MPM. With IMRT an increase in therapeutic dose to the pleural cavity and a reduction of doses to organs at risk (OAR) [for full text, please go to the a.m. URL], PTCOG 48; Meeting of the Particle Therapy Co-Operative Group

Published
2009
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45. PD-0416: Daily adaptive strategy simulation in lung cancer pts treated with RTCHT with reduced CTV-PTV MARGIN.

Author

Bonu, M.L., Borgetti, P., Spiazzi, L., Taddeo, A., Volpi, G., Guaineri, A., Costantino, G., Donofrio, A., Guerini, A., Tomasini, D., Toraci, C., Imbrescia, J., and Magrini, S.M.

Subjects
*LUNG cancer
Abstract

Poster discussion: CL: Lung PD-0416: Daily adaptive strategy simulation in lung cancer pts treated with RTCHT with reduced CTV-PTV MARGIN M.L. Bonu, P. Borgetti, L. Spiazzi, A. Taddeo, G. Volpi, A. Guaineri, G. Costantino, A. Donofrio, A. Guerini, D. Tomasini, C. Toraci, J. Imbrescia, S.M. Magrini. [Extracted from the article]

Published
2020
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46. How Has Prostate Cancer Radiotherapy Changed in Italy between 2004 and 2011? An Analysis of the National Patterns-Of-Practice (POP) Database by the Uro-Oncology Study Group of the Italian Society of Radiotherapy and Clinical Oncology (AIRO)

Author

Stefania Gottardo, Diana Greco, Simona Borghesi, Beatrice Detti, Gianluca Ingrosso, Paolo Antognoni, Umberto Ricardi, Alessandro Magli, Stefano Maria Magrini, Ercole Mazzeo, Luigi Spiazzi, Andrea Emanuele Guerini, Luca Frassinelli, Sara Nanni, Sara Bartoncini, Frank Lohr, Alessio Bruni, Rolando Maria D'Angelillo, Giulio Francolini, Stefano Arcangeli, Alessia Guarneri, Luca Triggiani, Mazzeo, E, Triggiani, L, Frassinelli, L, Guarneri, A, Bartoncini, S, Antognoni, P, Gottardo, S, Greco, D, Borghesi, S, Nanni, S, Bruni, A, Ingrosso, G, D'Angelillo, R, Detti, B, Francolini, G, Magli, A, Guerini, A, Arcangeli, S, Spiazzi, L, Ricardi, U, Lohr, F, and Magrini, S

Subjects
0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, genetic structures, medicine.medical_treatment, behavioral disciplines and activities, Article, Settore MED/06, Pattern Of Practice, Late toxicity, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Settore MED/36, Internal medicine, medicine, External beam radiotherapy, RC254-282, radiotherapy, Image-guided radiation therapy, Clinical Oncology, Radiotherapy, urogenital system, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, prostate cancer, Acute toxicity, body regions, Radiation therapy, 030104 developmental biology, 030220 oncology & carcinogenesis, Toxicity, business, psychological phenomena and processes
Abstract

Background and purpose: Two previous “Patterns Of Practice” surveys (POP I and POP II), including more than 4000 patients affected by prostate cancer treated with radical external beam radiotherapy (EBRT) between 1980 and 2003, established a “benchmark” Italian data source for prostate cancer radiotherapy. This report (POP III) updates the previous studies. Methods: Data on clinical management and outcome of 2525 prostate cancer patients treated by EBRT from 2004 to 2011 were collected and compared with POP II and, when feasible, also with POP I. This report provides data on clinical presentation, diagnostic workup, radiation therapy management, and toxicity as collected within the framework of POP III. Results: More than 50% of POP III patients were classified as low or intermediate risk using D’Amico risk categories as in POP II, 46% were classified as ISUP grade group 1. CT scan, bone scan, and endorectal ultrasound were less frequently prescribed. Dose-escalated radiotherapy (RT), intensity modulated radiotherapy (IMRT), image guided radiotherapy (IGRT), and hypofractionated RT were more frequently offered during the study period. Treatment was commonly well tolerated. Acute toxicity improved compared to the previous series, late toxicity was influenced by prescribed dose and treatment technique. Five-year overall survival, biochemical relapse free survival (BRFS), and disease specific survival were similar to those of the previous series (POP II). BRFS was better in intermediate- and high-risk patients treated with ≥ 76 Gy. Conclusions: This report highlights the improvements in radiotherapy planning and dose delivery among Italian Centers in the 2004–2011 period. Dose-escalated treatments resulted in better biochemical control with a reduction in acute toxicity and higher but acceptable late toxicity, as not yet comprehensively associated with IMRT/IGRT. CTV-PTV margins &gt, 8 mm were associated with increased toxicity, again suggesting that IGRT—allowing for tighter margins—would reduce toxicity for dose escalated RT. These conclusions confirm the data obtained from randomized controlled studies.

Published
2021

47. PO-1572: Use of intravoxel incoherent motion (IVIM) MRI for predicting dysphagia in oropharyngeal carcinoma.

Author

Maddalo, M., Altabella, L., Pegurri, L., Guerini, A., Peretto, G., Alghisi, A., Turla, O., Guaineri, A., Costantino, G., Spiazzi, L., Costa, L., Mozzetti, C., Pasinetti, N., and Buglione, M.

Subjects
*DEGLUTITION disorders, *MAGNETIC resonance imaging, *CARCINOMA, *FORECASTING, *RADIOMICS
Abstract

Poster: Physics track: Radiobiological and predictive modelling, and radiomics PO-1572: Use of intravoxel incoherent motion (IVIM) MRI for predicting dysphagia in oropharyngeal carcinoma M. Maddalo, L. Altabella, L. Pegurri, A. Guerini, G. Peretto, A. Alghisi, O. Turla, A. Guaineri, G. Costantino, L. Spiazzi, L. Costa, C. Mozzetti, N. Pasinetti, M. Buglione. [Extracted from the article]

Published
2020
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48. PO-0843: Assessment of weight loss and subjective dysphagia after radiotherapy for head and neck cancer.

Author

Maddalo, M., Costantino, G., Buglione, M., Spiazzi, L., Volpi, G., Premi, A., Donofrio, A., Guerini, A., Alghisi, A., Pedretti, S., Costa, L., Greco, D., Cominardi, C., Pegurri, L., and Magrini, S.M.

Subjects
*HEAD & neck cancer, *DEGLUTITION disorders, *RADIOTHERAPY
Abstract

Poster: Clinical track: Head and Neck PO-0843: Assessment of weight loss and subjective dysphagia after radiotherapy for head and neck cancer M. Maddalo, G. Costantino, M. Buglione, L. Spiazzi, G. Volpi, A. Premi, A. Donofrio, A. Guerini, A. Alghisi, S. Pedretti, L. Costa, D. Greco, C. Cominardi, L. Pegurri, S.M. Magrini. [Extracted from the article]

Published
2020
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