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Green fiscal reforms would contribute to climate change mitigation, increase the economic efficiency of national tax systems and provide additional public revenues. Some countries in Latin America have already taken first steps towards green fiscal reforms. This outlook article provides an overview of the major challenges for the successful implementation of such reforms and discusses how they could be overcome.

With its abundance of renewable energy potentials, not only for hydropower and bioenergy, but also for wind and solar, Brazil provides good prospects for a carbon neutral energy system. The role of an enhanced coupling of the power, heat and transport sectors in such systems is not yet fully understood. This paper analyses the least-cost composition and operation of a fully renewable power supply system as part of a carbon neutral energy supply in Brazil. It relies on the application of the high-resolution energy system model REMix. Our analysis reveals that the expansion of wind and solar power is more cost-efficient than the construction of additional hydroelectric plants. This is favoured because the existing hydroelectric plants offer large capacity of dispatchable power to compensate for fluctuations, and thus no additional storage is necessary. Furthermore, the REMix analysis indicates that varying shares of solar and wind power technologies as well as the spatial distribution of power generation have only a small influence on supply costs. This implies that the transformation strategy in Brazil can be primarily based on other criteria such as regional development, public acceptance, environmental impact or industrial policy without major impacts on system costs. [ABSTRACT FROM AUTHOR]

The Ecuador's expansion plans for the power sector promote the exploitation of hydro power potential, natural gas and a small share of alternative renewable energies. In 2019, electricity generation reached 76.3% from hydroelectric power, 21.9% from thermal plants and 1.8% from other renewable resources. Although the power energy mix is mainly based on renewable technologies, the total energy demand is still dependent on fossil fuels, which is the case of the transport sector that alone accounted for 50% of the total primary energy consumed in the country. This paper analyzes the pathway to develop a clean and diversified electricity mix, covering the demand of three specific development levels of electric transportation. The linear optimization model (urbs) and the Ecuador Land Use and Energy Netwrok Analysis (ELENA) are used to optimize the expansion of the power system in the period from 2020 to 2050. Results show that reaching an electricity mix 100% based on renewable energies is possible and still cover a highly electrified transport that includes 47.8% of land passenger, and 5.9% of land freight transport. Therefore, the electrification of this sector is a viable alternative for the country to rely on its own energy resources, while reinforcing its future climate change mitigation commitments. [ABSTRACT FROM AUTHOR]

Abstract Exposure to ambient particulate matter (PM) caused an estimated 4.2 million deaths worldwide in 2015. However, PM emission standards for power plants vary widely. To explore if the current levels of these standards are sufficiently stringent in a simple cost-benefit framework, we compared the health benefits (avoided monetized health costs) with the control costs of tightening PM emission standards for coal-fired power plants in Northeast (NE) Brazil, where ambient PM concentrations are below World Health Organization (WHO) guidelines. We considered three Brazilian PM 10 (PM x refers to PM with a diameter under x micrometers) emission standards and a stricter U.S. EPA standard for recent power plants. Our integrated methodology simulates hourly electricity grid dispatch from utility-scale power plants, disperses the resulting PM 2.5 , and estimates selected human health impacts from PM 2.5 exposure using the latest integrated exposure-response model. Since the emissions inventories required to model secondary PM are not available in our study area, we modeled only primary PM so our benefit estimates are conservative. We found that tightening existing PM 10 emission standards yields health benefits that are over 60 times greater than emissions control costs in all the scenarios we considered. The monetary value of avoided hospital admissions alone is at least four times as large as the corresponding control costs. These results provide strong arguments for considering tightening PM emission standards for coal-fired power plants worldwide, including in regions that meet WHO guidelines and in developing countries. Graphical abstract Health benefits and control costs of tightening PM 10 standards for coal power plants in NE Brazil. Unlabelled Image Highlights • We compare health benefits and control costs of tightening PM 10 emissions standards. • We model electricity generation in NE Brazil and focus on coal power plants. • In our study area, PM concentrations are below WHO guidelines. • We combine an hourly dispatch model with dispersion and health assessment models. • Benefits of tighter PM 10 emission standards exceed control costs by a factor > 60. [ABSTRACT FROM AUTHOR]

Aim: To develop a fast, low-cost diagnostic strategy to identify single point mutations in highly variable genomes such as hepatitis C virus (HCV)., Methods: In patients with HCV infection, resistance-associated amino acid substitutions within the viral quasispecies prior to therapy can confer decreased susceptibility to direct-acting antiviral agents and lead to treatment failure and virological relapse. One such naturally occurring mutation is the Q80K substitution in the HCV-NS3 protease gene, which confers resistance to PI inhibitors, particularly simeprevir. Low-cost, highly sensitive techniques enabling routine detection of these single point mutations would be useful to identify patients at a risk of treatment failure. LightCycler methods, based on real-time PCR with sequence-specific probe hybridization, have been implemented in most diagnostic laboratories. However, this technique cannot identify single point mutations in highly variable genetic environments, such as the HCV genome. To circumvent this problem, we developed a new method to homogenize all nucleotides present in a region except the point mutation of interest., Results: Using nucleotide-specific probes Q, K, and R substitutions at position 80 were clearly identified at a sensitivity of 10% (mutations present at a frequency of at least 10% were detected). The technique was successfully applied to identify the Q80K substitution in 240 HCV G1 serum samples, with performance comparable to that of direct Sanger sequencing, the current standard procedure for this purpose. The new method was then validated in a Catalonian population of 202 HCV G1-infected individuals. Q80K was detected in 14.6% of G1a patients and 0% of G1b in our setting., Conclusion: A fast, low-cost diagnostic strategy based on real-time PCR and fluorescence resonance energy transfer probe melting curve analysis has been successfully developed to identify single point mutations in highly variable genomes such as hepatitis C virus. This technique can be adapted to detect any single point mutation in highly variable genomes., Competing Interests: Conflict-of-interest statement: There are no conflicts of interest to report.