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Ambient audio sampling methods such as the Electronically Activated Recorder (EAR) have become increasingly prominent in clinical and social sciences research. These methods record snippets of naturalistically assessed audio from participants' daily lives, enabling novel observational research about the daily social interactions, identities, environments, behaviors, and speech of populations of interest. In practice, these scientific opportunities are equaled by methodological challenges: researchers' own cultural backgrounds and identities can easily and unknowingly permeate the collection, coding, analysis, and interpretation of social data from daily life. Ambient audio sampling poses unique and significant challenges to cultural humility, diversity, equity, and inclusivity (DEI) in scientific research that require systematized attention. Motivated by this observation, an international consortium of 21 researchers who have used ambient audio sampling methodologies created a workgroup with the aim of improving upon existing published guidelines. We pooled formally and informally documented challenges pertaining to DEI in ambient audio sampling from our collective experience on 40+ studies (most of which used the EAR app) in clinical and healthy populations ranging from children to older adults. This article presents our resultant recommendations and argues for the incorporation of community-engaged research methods in observational ambulatory assessment designs looking forward. We provide concrete recommendations across each stage typical of an ambient audio sampling study (recruiting and enrolling participants, developing coding systems, training coders, handling multi-linguistic participants, data analysis and interpretation, and dissemination of results) as well as guiding questions that can be used to adapt these recommendations to project-specific constraints and needs., (© 2023. The Psychonomic Society, Inc.)

Pet ownership has often been lauded as a protective factor for well-being, particularly during the COVID-19 pandemic. We expanded this question to consider how pet (i.e., species, number) and owner (i.e., pet relationship quality, personality, attachment orientations) characteristics affected the association between pet ownership and well-being in a pre-registered mixed method analysis of 767 people assessed three times in May 2020. In our qualitative analyses, pet owners listed both benefits and costs of pet ownership during the COVID-19 pandemic. In our quantitative analyses, we found that pet ownership was not reliably associated with well-being. Furthermore, this association largely did not depend on the number of pets owned, the species of pet(s) owned, the quality of the human-pet relationship, or the owner's psychological characteristics. Our findings are consistent with a large body of research showing null associations of pet ownership on well-being (quantitatively) but positive reports of pet ownership (qualitatively)., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Existing research on racial/ethnic differences in stress and coping is limited by small samples, single-item measures, and lack of inclusion of Mexican Americans. We address these gaps by analyzing data from the Texas City Stress and Health Study, a cross-sectional sample of Black (N = 257), White (N = 304), US-born (N = 689), and foreign-born (N = 749) Mexican Americans residing in proximity to a petrochemical complex. We compared active and avoidant coping by race/ethnicity and explored multivariable associations between coping and perceived stress. Black and foreign-born Mexican American respondents had the highest stressor exposure yet displayed different patterns of coping and perceived stress patterns. Active coping may be particularly effective for African Americans but may not offset extreme stress disparities. For Mexican Americans, the lack of association between coping and stress underscores the need for more work focused on the culturally diverse coping experiences., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

A large body of research suggests that extraversion is positively related to well-being. However, it is unclear whether this association can be explained by social participation (i.e., more extraverted individuals engage in social interactions more frequently) or social reactivity (i.e., more extraverted individuals profit more from social interactions) processes. Here, we examined the role of social interactions for the extraversion-well-being relationship during the COVID-19 pandemic, an unprecedented time of reduced social contact. We analyzed data from an international, longitudinal study (Study 1: 10,523 assessments provided by 4,622 participants) and two experience sampling studies (Study 2: 29,536 assessments provided by 293 participants; Study 3: 61,492 assessments provided by 1,381 participants). Preregistered multilevel structural equation models revealed that extraversion was robustly related to well-being, even when social restrictions were in place. Across data sets, we found some support for the social participation hypothesis (i.e., the relationship between extraversion and well-being is mediated by social interactions), but the social reactivity hypothesis (i.e., extraversion moderates the relationship between social interactions and well-being) was not consistently supported. Strikingly, however, exploratory analyses showed that the social reactivity hypothesis was supported for specific facets of extraversion (i.e., sociability) and well-being (i.e., activated positive affect). Moreover, changes in social interaction patterns during the COVID-19 pandemic (e.g., decreases in face-to-face interactions and interactions with friends) were unrelated to extraversion, and more extraverted individuals did not suffer more from these changes. Taken together, these findings underline the robustness of the effect of extraversion on well-being during a societal crisis. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

A growing body of research has established responsiveness as a robust predictor of physical health. Here, we evaluate the extent to which this work establishes partner responsiveness as an active ingredient- a specific component within the broader construct of relationship quality that accounts for a demonstrated association between relationship quality and health. We review work demonstrating that responsiveness predicts a wide range of physical health outcomes, above and beyond other facets of relationship quality, and that it moderates the effects of other protective processes and risk factors. Finally, we discuss how new methodological and interdisciplinary approaches can provide generalizable, causal, and mechanistic evidence to further validate responsiveness as an active ingredient linking relationships and health., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Ltd. All rights reserved.)

Synthetic glucocorticoids, such as dexamethasone, have been used as a treatment for many immune conditions, such as asthma and, more recently, severe COVID-19. Single-cell data can capture more fine-grained details on transcriptional variability and dynamics to gain a better understanding of the molecular underpinnings of inter-individual variation in drug response. Here, we used single-cell RNA-seq to study the dynamics of the transcriptional response to glucocorticoids in activated peripheral blood mononuclear cells from 96 African American children. We used novel statistical approaches to calculate a mean-independent measure of gene expression variability and a measure of transcriptional response pseudotime. Using these approaches, we showed that glucocorticoids reverse the effects of immune stimulation on both gene expression mean and variability. Our novel measure of gene expression response dynamics, based on the diagonal linear discriminant analysis, separated individual cells by response status on the basis of their transcriptional profiles and allowed us to identify different dynamic patterns of gene expression along the response pseudotime. We identified genetic variants regulating gene expression mean and variability, including treatment-specific effects, and showed widespread genetic regulation of the transcriptional dynamics of the gene expression response., (© 2023 Resztak et al.; Published by Cold Spring Harbor Laboratory Press.)

This in-depth critical review investigates the impact of COVID-19 on personal relationships from the start of the pandemic in early 2020 to September 2021. Research examining six themes are identified and described in detail: the impact of COVID-19 on (1) family and intimate relationships; (2) LGBTQ+ relationships; (3) how COVID-19 is linked to technologically mediated communication and personal relationships; (4) potential shifts in sexual behaviors and desire; (5) potential shifts in relational conflict and intimate partner violence; and (6) constructive aspects of personal relationships, which is a broad theme that includes outcomes such as resilience, relational quality, coping, and social support. Findings for overarching patterns are offered to highlight implications for current research and identify future directions to consider when continuing to study personal relationships during the COVID-19 pandemic and similar future crises., (© The Author(s) 2022.)

Objective: This study investigated the links between naturalistically observed and self-reported interpersonal problems, diabetes management, and glucose levels in older adolescents and young adults with type 1 diabetes., Design: Sixty-eight older adolescents and young adults (aged 17-20 years) participated in a cross-sectional study that consisted of three home visits and a daily diary segment., Main Outcome Measures: Participants wore the Electronically Activated Recorder (EAR) for four days to capture interpersonal problems and wore a continuous glucose monitor for blood glucose levels. Researchers also collected HbA1 c values, conducted an interview to assess diabetes management, and collected participant-reported severity of interpersonal problems., Results: High EAR-observed interpersonal problems were associated with poor diabetes management. Multiple regression analyses revealed that high EAR-observed interpersonal problems continued to explain variance in poor diabetes management after including self-reported interpersonal problems and covariates., Conclusion: These findings corroborate literature suggesting that negative interactions are associated with type 1 diabetes management. This study is the first to use the EAR to capture naturalistically observed interactions in this population and identify its utility beyond self-reports. These findings highlight the importance of considering naturalistically observed interactions when developing interventions to promote better diabetes management in older adolescents and young adults.

Puberty is an important developmental period marked by hormonal, metabolic and immune changes. Puberty also marks a shift in sex differences in susceptibility to asthma. Yet, little is known about the gene expression changes in immune cells that occur during pubertal development. Here we assess pubertal development and leukocyte gene expression in a longitudinal cohort of 251 children with asthma. We identify substantial gene expression changes associated with age and pubertal development. Gene expression changes between pre- and post-menarcheal females suggest a shift from predominantly innate to adaptive immunity. We show that genetic effects on gene expression change dynamically during pubertal development. Gene expression changes during puberty are correlated with gene expression changes associated with asthma and may explain sex differences in prevalence. Our results show that molecular data used to study the genetics of early onset diseases should consider pubertal development as an important factor that modifies the transcriptome., (© 2023. The Author(s).)

The COVID-19 pandemic has touched many aspects of people's lives around the world, including their romantic relationships. While media outlets have reported that the pandemic is difficult for couples, empirical evidence is needed to test these claims and understand why this may be. In two highly powered studies ( N = 3271) using repeated measure and longitudinal approaches, we found that people who experienced COVID-19 related challenges (i.e., lockdown, reduced face-to-face interactions, boredom, or worry) also reported greater self and partner phone use (Study 1) and time spent on social media (Study 2), and subsequently experienced more conflict and less satisfaction in their romantic relationship. The findings provide insight into the struggles people faced in their relationships during the pandemic and suggest that the increase in screen time - a rising phenomenon due to the migration of many parts of life online - may be a challenge for couples., (© The Author(s) 2022.)

The COVID-19 pandemic and the resulting social distancing measures have caused widespread social and economic disruptions, resulting in spikes in unemployment and financial instability, along with drastic changes to people's ability to feel socially connected. Many of the changes resulting from the COVID-19 pandemic are risk factors for depressive symptoms, which are associated with lower levels of sexual desire. The current research (N = 4,993) examined whether responses to external stressors brought on by COVID-19 (i.e., financial concern, worry, loneliness, stress) were associated with sexual desire among a multi-national sample of people in relationships (Studies 1-2), and whether this association was, in part, due to reports of depressive symptoms (Study 2). In the period immediately following the onset of the pandemic, more financial concern (Study 1) and worry (Study 2) were associated with higher sexual desire, while other factors, like stress (Studies 1-2), were associated with lower desire. We also followed a subset of participants every two weeks during the initial stages of the pandemic and at times when people reported greater stress, loneliness, financial strain, or worry than their average, they reported greater depressive symptoms, which was, in turn, associated with lower sexual desire. Results suggest that the social isolation and stress resulting from the COVID-19 pandemic have mixed associations with sexual desire at the onset of the pandemic. But over time, when people report heightened COVID-related stressors, they tend to report lower sexual desire for their partner, in part because these stressors are associated with more depressive symptoms., (© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Objective: Although psychosocial stressors in the home environment place children at risk for physical health problems, less is known about whether or how peer stressors contribute to health problems in youth. The current study investigated associations between daily peer problems and asthma symptoms among adolescents with asthma. The possible mediating role of nightly sleep disturbance and the moderating role of adolescent mental health were also examined., Method: Adolescents ( N = 297) with asthma reported on peer problems, nighttime awakenings, sleep quality, and asthma symptoms over 4 days. Youth also self-administered daily peak expiratory flow rate (PEFR) assessments, and parents reported on their children's anxious-depressive symptoms., Results: Adolescents encountering more daily peer problems experienced more severe asthma symptoms, but not lower PEFR. Mediation analyses demonstrated that associations between daily peer problems and subjective asthma symptoms were partially explained by more nighttime awakenings and lower sleep quality, even after accounting for potentially confounding demographic factors and adolescents' daily experiences of familial stress. However, these indirect pathways did not vary depending on youth anxious-depressive symptoms., Conclusions: The findings provide novel evidence for everyday peer stress as a developmentally relevant health risk factor among adolescents with asthma. Insofar as daily peer problems were associated with elevated asthma symptoms via impaired sleep, psychosocial interventions focusing on the peer context may help mitigate maladaptive health behaviors and asthma morbidity. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Objective: The current research aims to examine a potential explanation for SES disparities in youth medication adherence: the frequency of children's daily routines., Design: In a cross-sectional sample of 194 youth with asthma (112 boys and 82 girls; average age = 12.8 years old) and their primary caregivers primarily from the Detroit metropolitan area, caregivers reported their SES and the frequency of their children's daily routines during the first laboratory visit. At a follow-up visit, caregivers and their children completed the Family Asthma Management System Scale (FAMSS), a well-validated, semi-structured interview that assess children's degree of adherence to prescribed medications., Main Outcome Measures: Children's daily routines were measured with the Child Routines Inventory while children's medication adherence was measured with the FAMSS., Results: Mediation analyses revealed that the association between subjective (but not objective) SES and medication adherence was partially mediated by the frequency of children's daily routines., Conclusion: These results suggest that the frequency of children's daily routines is an important factor linking SES and medication adherence, a finding with important implications for improving health outcomes and reducing health disparities between low SES children and their high SES counterparts.

Objective: To investigate the role of caregiver- and youth-reports of parent-child conflict on trajectories of asthma-related health outcomes over 2 years., Methods: In a sample of 193 youth with asthma (42.7% female; M age = 12.78) and their primary caregivers, we used a multi-method and multi-informant approach to assess self-reported parent-child conflict from youth and caregivers at both the daily and global levels at baseline. Next, we annually assessed subjective (i.e., youth self-reported asthma symptoms) and clinical (i.e., peak flow) asthma health outcomes for 2 years., Results: Latent growth curve models revealed an effect of baseline youth-reported global family conflict on peak flow trajectories such that youth who reported greater parent-child conflict at baseline experienced less of an increase in peak flow over time than youth who reported less parent-child conflict at baseline (standardized β = -0.27, p = .003)., Conclusions: Youth with asthma who perceive greater overall conflict with their caregivers experience less improvement in peak flow as they age. The research and clinical implications of these findings are discussed., (Copyright © 2021 Elsevier Inc. All rights reserved.)

This study used ecological sampling methods to examine associations between youth athletes' experiences receiving and engaging in behaviors indicative of in-group ties, cognitive centrality, and in-group affect (i.e., social identity) during a 3-day competitive ice hockey tournament. Forty-five youth (Mage = 12.39 years; SDage = 1.14 years; 94% male) from nine teams wore an electronically activated recorder that captured brief (50-s) audio observations throughout the tournament. Participants also completed daily diary questionnaires for each day of competition. Multilevel structural equation modeling demonstrated that athletes were more likely to engage in behaviors indicative of in-group affect and cognitive centrality on days when they received as higher-than-average frequency of behaviors indicative of cognitive centrality from teammates, coaches, and parents. The findings suggest that when team members interact in ways that demonstrate they are thinking about their team, they influence fellow members to behave in ways that promote a sense of "us."

Objectives: Children who grow up in more socioeconomically disadvantaged homes experience greater levels of inflammation and worse asthma symptoms than children from more advantaged families. However, recent evidence suggests that certain family-level factors can mitigate health disparities associated with socioeconomic status (SES). In a sample of youth with asthma, we investigated the potential buffering effects of maternal involvement and warmth on SES disparities in asthma-related immune responses, assessed via glucocorticoid resistance (GR) of immune cells., Methods: One hundred and forty-three youth (10-16 years of age) with asthma completed measures of maternal involvement and warmth, and their primary caregivers reported their levels of education, income, and financial stress. Peripheral blood mononuclear cells from youth's blood were isolated, cultured, and assayed to determine mitogen-stimulated (PMA/INO + Etho) and mitogen/hydrocortisone-stimulated (PMA/INO + Cort) levels of two Th-2 cytokines (i.e., interleukin-5, interleukin-13) and one Th-1 cytokine (i.e., interferon-γ). GR was calculated by subtracting log-transformed cytokine concentration in the PMA/INO + Etho samples from log-transformed cytokine concentration in the PMA/INO + Cort samples., Results: Both maternal involvement and warmth moderated the indirect pathway from family SES to GR of Th-2 cytokines via financial stress. Specifically, we found that low family SES was associated with elevated GR of Th-2 cytokines via increased financial stress among youth reporting low levels of maternal involvement and warmth, but not among those reporting high levels of maternal involvement or warmth., Conclusions: These results highlight the protective role of maternal involvement and warmth in health-related biological processes modulated by family SES among youth with asthma., (Copyright © 2021 Elsevier Inc. All rights reserved.)

Social interactions and the overall psychosocial environment have a demonstrated impact on health, particularly for people living in disadvantaged urban areas. Here, we investigated the effect of psychosocial experiences on gene expression in peripheral blood immune cells of children with asthma in Metro Detroit. Using RNA-sequencing and a new machine learning approach, we identified transcriptional signatures of 19 variables including psychosocial factors, blood cell composition, and asthma symptoms. Importantly, we found 169 genes associated with asthma or allergic disease that are regulated by psychosocial factors and 344 significant gene-environment interactions for gene expression levels. These results demonstrate that immune gene expression mediates the link between negative psychosocial experiences and asthma risk., Competing Interests: JR, AF, HM, AA, XW, DW, SZ, RS, RP, FL No competing interests declared, (© 2021, Resztak et al.)

Advances in mobile and wearable technologies mean it is now feasible to record hours to days of participant behavior in its naturalistic context, a great boon for psychologists interested in family processes and development. While automated activity recognition algorithms exist for a limited set of behaviors, time-consuming human annotations are still required to robustly characterize the vast majority of behavioral and affective markers of interest. This report is the first to date which systematically tests the efficacy of different sampling strategies for characterizing behavior from audio recordings to provide practical guidelines for researchers. Using continuous audio recordings of the daily lives of 11 preschool-aged children, we compared sampling techniques to determine the most accurate and efficient approach. Results suggest that sampling both low and high frequency verbal and overt behaviors is best if samples are short in duration, systematically rather than randomly selected, and sampled to cover at least 12.5% of recordings. Implications for assessment of real-world behavior are discussed. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Reports an error in "Housework, health, and well-being in older adults: The role of socioeconomic status" by Jacqueline Rodriguez-Stanley, María Alonso-Ferres, Samuele Zilioli and Richard B. Slatcher ( Journal of Family Psychology , 2020[Aug], Vol 34[5], 610-620). In the article (http://dx.doi.org/10 .1037/fam0000630), values are incorrectly reported in columns 1-3 of Table 1 and in the "Eudaimonic well-being," "Physical health," and "Sleep dysfunction" columns of Table 2. Although the significance of the associations and analyses remain unchanged, the corrected table columns are included in the erratum. (The following abstract of the original article appeared in record 2020-09875-001.) For most adults, household chores are undesirable tasks yet need to be completed regularly. Previous research has identified absolute hours spent on household chores and one's perceived fairness of the housework distribution as predictors of romantic relationship quality and well-being outcomes. Drawing from the Equity Theory, we hypothesized that perceived fairness acts as an underlying psychological mechanism linking household chores hours to long-term effects of relationship quality, well-being, physical health, and sleep quality in a sample of 2,644 married and cohabiting adults from the Midlife Development in the U.S. study. Additionally, following the Reserve Capacity Model, socioeconomic status (SES) was tested as a moderator because of its association with exposure to stressors and psychological resources which contribute to perceived fairness. Moderated mediation results showed significant indirect effects of household chore hours through perceived fairness on prospective measures of well-being, marital quality, physical health, and sleep dysfunction among individuals of lower SES but not higher SES when controlling for age, sex, and paid work hours. These results highlight the importance of perceived fairness and the influence of SES in the links among household chores and long-term relationship processes, health, and well-being. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

For most adults, household chores are undesirable tasks yet need to be completed regularly. Previous research has identified absolute hours spent on household chores and one's perceived fairness of the housework distribution as predictors of romantic relationship quality and well-being outcomes. Drawing from the Equity Theory, we hypothesized that perceived fairness acts as an underlying psychological mechanism linking household chores hours to long-term effects of relationship quality, well-being, physical health, and sleep quality in a sample of 2,644 married and cohabiting adults from the Midlife Development in the U.S. study. Additionally, following the Reserve Capacity Model, socioeconomic status (SES) was tested as a moderator because of its association with exposure to stressors and psychological resources which contribute to perceived fairness. Moderated mediation results showed significant indirect effects of household chore hours through perceived fairness on prospective measures of well-being, marital quality, physical health, and sleep dysfunction among individuals of lower SES but not higher SES when controlling for age, sex, and paid work hours. These results highlight the importance of perceived fairness and the influence of SES in the links among household chores and long-term relationship processes, health, and well-being. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

The current study tested whether positive and negative behaviors exhibited by couples during conflict interactions assessed in the laboratory are associated with individuals' diurnal cortisol patterns (i.e., circadian rhythms in cortisol across the course of the day) outside of the lab. Participants (N = 82) provided a total of 18 salivary cortisol samples over a 3-day period and came into the lab with their spouse to engage in two ten-minute dyadic conflict discussions. These videotaped interactions were coded to assess the intensity with which couples displayed various positive behaviors (e.g., humor, affection) and negative behaviors (e.g., defensiveness, frustration) during the conflict discussions. Multi-level modeling was used to examine the associations between couples' positive and negative behavior during conflict discussions and diurnal cortisol patterns in daily life. Results showed links between overall positive, but not negative, behaviors and diurnal cortisol patterns. Individuals who experienced more positive behaviors with their partner during the conflict discussion showed a steeper ("healthier") cortisol slope across the day in their daily lives. Exploratory analyses investigating the association between specific positive and negative behaviors and diurnal cortisol revealed that affection and scorn were associated with diurnal cortisol patterns in daily life. This research advances our understanding of the impact of social relationships on physical health from a biopsychosocial perspective and has implications for understanding how the ways in which couples resolve conflict are linked to health-related biological processes in daily life., Competing Interests: Declaration of Competing Interest None., (Copyright © 2020 Elsevier Ltd. All rights reserved.)

Self-disclosure and perceived responsiveness are important building blocks of social relationships that have long-lasting consequences for health and well-being. However, the conditions under which self-disclosure and responsiveness are likely to benefit health, and how early in life these benefits arise, remain unclear. Among 141 youth (aged 10-17) with asthma, we investigated how average daily levels of self-disclosure and responsiveness are linked to positive and negative affect and the expression of the glucocorticoid receptor gene NR3C1 , a marker of improved regulation of stress physiology and immune functioning. Higher levels of self-disclosure were associated with higher NR3C1 expression and positive affect only when perceptions of responsiveness were high. Furthermore, perceived responsiveness was linked to NR3C1 expression for females but not males. These results suggest that the potential benefits of self-disclosure depend on the extent to which interaction partners are perceived as responsive and that these benefits emerge prior to adulthood.

This article introduces and outlines the case for an evolutionary mismatch between smartphones and the social behaviors that help form and maintain close social relationships. As psychological adaptations that enhance human survival and inclusive fitness, self-disclosure and responsiveness evolved in the context of small kin networks to facilitate social bonds, promote trust, and enhance cooperation. These adaptations are central to the development of attachment bonds, and attachment theory is a middle-level evolutionary theory that provides a robust account of the ways human bonding provides for reproductive and inclusive fitness. Evolutionary mismatches operate when modern contexts cue ancestral adaptations in a manner that does not provide for their adaptive benefits. We argue that smartphones and their affordances, although highly beneficial in many circumstances, cue humans' evolved needs for self-disclosure and responsiveness across broad virtual networks and, in turn, have the potential to undermine immediate interpersonal interactions. We review emerging evidence on the topic of technoference , which is defined as the ways in which smartphone use may interfere with or intrude into everyday social interactions. The article concludes with an empirical agenda for advancing the integrative study of smartphones, intimacy processes, and close relationships.

Prior evidence suggests that an individual's attachment orientation is linked to the health and health-related biology of his/her romantic relationship partners. The current study examined whether this effect extends to parent-child relationships. Specifically, we investigated the association between maternal attachment anxiety and avoidance and diurnal cortisol of offspring. In a sample of 138 youth with asthma and their primary caregivers, caregivers reported their attachment orientations, and their children (aged 10-17) supplied four saliva samples per day over four days to assess diurnal cortisol patterns. Growth curve analyses revealed no links to caregiver attachment anxiety, but caregiver attachment avoidance was significantly associated with children's diurnal cortisol slopes, such that greater attachment avoidance predicted flatter diurnal cortisol slopes. Maternal warmth did not mediate this link. These results support the possibility that an individual's adult attachment orientation may "get under the skin" of family members to influence their health-related biology. Future research should seek to determine the causal direction of this association and mechanisms of this effect.

Objective: This study tested longitudinal associations between absolute levels of perceived partner responsiveness (PPR; how much people perceive that their romantic partners understand, care for, and appreciate them), daily negative affect reactivity and positive affect reactivity, and all-cause mortality in a sample of 1,208 adults for three waves of data collection spanning 20 years. We also tested whether longitudinal changes in PPR predicted mortality via affect reactivity., Methods: Data were taken from the National Survey of Midlife Development in the United States. PPR was assessed at waves 1 and 2, affect reactivity to stressors was assessed by daily diary reports at wave 2, and mortality status was obtained at wave 3., Results: Mediation analyses revealed absolute levels of PPR at wave 1 predicted wave 3 mortality via wave 2 affective reactivity in the predicted direction, but this did not remain robust when statistically accounting for covariates (e.g., marital risk, neuroticism), β = .004, 95% confidence interval = -.03 to .04. However, wave 1-2 PPR change predicted negative affect (but not positive affect) reactivity to daily stressors at wave 2, which then predicted mortality risk a decade later (wave 3); these results held when adjusting for relevant demographic, health, and psychosocial covariates, β = -.04, 95% confidence interval = -.09 to -.002., Conclusions: These findings are among the first to provide direct evidence of psychological mechanisms underlying the links between intimate relationships and mortality and have implications for research aiming to develop interventions that increase or maintain responsiveness in relationships over time.

Close relationships are known to predict physical health outcomes. The time has come for a shift toward achieving a better understanding of the underlying mechanisms. One promising group of psychological mechanisms is affective processes, such as discrete emotions, emotion regulation, and affect reactivity. In this paper, we discuss the evidence linking relationship functioning with both the positive and negative valences of each affective process, considering the contributions of different types of close relationships across the lifespan, and the evidence for each affective process impacting physical health. We note evidence suggesting that affective processes may also have a causal impact on relationship function. When available, we review literature testing full mediational pathways, from relationship functioning to affective processes to physical health, as the ideal methodology for testing these links. Finally, we identify core themes and propose key future directions for this research.

The glucocorticoid receptor gene NR3C1 is an important down-regulator of inflammation and is typically under-expressed in individuals with low socioeconomic status (SES). Negative emotionality has been suggested as a potential mediator of SES disparities in health outcomes. In this study, we expand this literature by naturalistically assessing negative emotionality in a key emotional environment: the family. In a sample of 104 youth with asthma (10-17 years) and their primary caregiver, we assessed SES via caregiver report, emotional expression by youth and parents in the home over four days using the electronically activated recorder (EAR), and NR3C1 expression via blood collected from youth. Although there was not a direct effect of SES on NR3C1 expression, bootstrapping mediation analyses showed a significant indirect path such that lower SES was associated with a more negative family emotional climate, which in turn predicted reduced NR3C1 expression. No mediation effects were found for family positive emotional climate. This research demonstrates the importance of examining the effects of SES on emotion expression in the family context and suggests a critical biopsychosocial pathway underlying SES-based health disparities that may extend beyond youth., (Copyright © 2018 Elsevier Ltd. All rights reserved.)

Quality of marital relationships is consistently linked to personal well-being. However, almost all of the studies linking marital processes to well-being have been conducted in Western (particularly North American) countries. Growing evidence shows that perceived partner responsiveness is a central relationship process predicting well-being in Western contexts but little is known about whether this association generalizes to other countries. The present work investigated whether the predictive role of perceived partner responsiveness in well-being differs across the United States and Japan-2 contexts with contrasting views on how the self is conceptualized in relation to the social group. A large life span sample of married or long-term cohabiting adults (n = 3,079, age range = 33-83 in the United States and n = 861, age range = 30-79 in Japan) completed measures of perceived partner responsiveness, hedonic and eudaimonic well-being, and demographic (age, gender, education) and personality (extraversion and neuroticism) covariates known to predict well-being. Perceived partner responsiveness positively predicted hedonic and eudaimonic well-being both in the U.S. and in Japan. However, perceived partner responsiveness more strongly predicted both types of well-being in the United States as compared with Japan. The difference in slopes across the 2 countries was greater for eudaimonic as compared with hedonic well-being. The interaction between perceived partner responsiveness and country held even after controlling for demographic factors and personality traits. By showing that the role of perceived partner responsiveness in well-being may be influenced by cultural context, our findings contribute to achieving a more nuanced picture of the role of relationships in personal well-being. (PsycINFO Database Record, ((c) 2018 APA, all rights reserved).)

Rationale: Patient-physician communication plays an essential role in a variety of patient outcomes; however, it is often difficult to operationalize positive patient-physician communication objectively, and the existing evaluation tools are generally time-consuming., Objective: This study proposes semantic similarity of the patient's and physician's language in a medical interaction as a measure of patient-physician communication. Latent semantic analysis (LSA), a mathematical method for modeling semantic meaning, was employed to assess similarity in language during clinical interactions between physicians and patients., Methods: Participants were 132 Black/African American patients (76% women, Mage = 43.8, range = 18-82) who participated in clinical interactions with 17 physicians (53% women, Mage = 27.1, range = 26-35) in a primary care clinic in a large city in the Midwestern United States., Results: LSA captured reliable information about patient-physician communication: The mean correlation indicating similarity between the transcripts of a physician and patient in a clinical interaction was 0.142, significantly greater than zero; the mean correlation between a patient's transcript and transcripts of their physician during interactions with other patients was not different from zero. Physicians differed significantly in the semantic similarity between their language and that of their patients, and these differences were related to physician ethnicity and gender. Female patients exhibited greater communication similarity with their physicians than did male patients. Finally, greater communication similarity was predicted by less patient trust in physicians prior to the interaction and greater patient trust after the interaction., Conclusion: LSA is a potentially important tool in patient-physician communication research. Methodological considerations in applying LSA to address research questions in patient-physician communication are discussed., (Copyright © 2017 Elsevier Ltd. All rights reserved.)

Research has demonstrated links between adult romantic attachment and one's own physical health; little is known about links between adult attachment orientations and offspring health. Prior work has shown that parents' greater attachment anxiety and avoidance predicts less warmth toward their children. Extensive work has also shown that lower maternal warmth has negative downstream effects on offspring health. We tested the novel hypothesis that mothers' dispositional romantic attachment would be linked-via maternal warmth-to their children's expression of the glucocorticoid receptor gene NR3C1 , higher expression of which is associated with healthier stress-regulation and inflammatory response. In a sample of 132 youth with asthma, we found that mothers' attachment anxiety and avoidance were both negatively associated with children's expression of NR3C1 , explained by lower youth-rated maternal warmth. Effects held after adjusting for demographic and psychosocial covariates. Implications for parents' attachment influencing the health of offspring are discussed.

Previous studies have shown that living in poor neighborhoods is associated with increased morbidity and mortality. However, researchers are now investigating the biological pathways responsible for the deleterious effects of neighborhood disadvantage on health. This study investigated whether neighborhood disadvantage (i.e., a measure of relative neighborhood quality derived by combining social and built environmental conditions) was associated with hair cortisol-a retrospective indicator of long-term hypothalamic pituitary adrenal (HPA) axis activation-and whether this link would be mediated by self-reported neighborhood satisfaction. Forty-nine older African Americans were recruited from thirty-nine Detroit census tracts across five strata of census tract adversity. Participants were interviewed face-to-face to collect psychosocial measures. Each provided a hair sample for analysis of cortisol. Multiple regression analyses revealed that higher neighborhood disadvantage was associated with higher levels of hair cortisol levels and that neighborhood satisfaction partially explained this association. These results are the first to our knowledge to demonstrate a direct link between neighborhood disadvantage and hair cortisol in a sample of older adults and to show that self-reported neighborhood satisfaction may be a psychological intermediary of this association., (Copyright © 2017 Elsevier Ltd. All rights reserved.)

Objective: Among older children and adolescents, keeping secrets from parents is consistently associated with lower levels of psychological well-being. Further, concealing one's thoughts and emotions has been associated with poor physical health outcomes in adults. However, it remains an open question whether secret-keeping is associated with poorer health and health-related behaviors (such as sleep) among youth and, if those hypothesized links exist, what the psychological mechanisms might be. We investigated the associations among youth secrecy towards parents, daily asthma symptoms and daily sleep behaviors in a sample of low-income youth with asthma aged 10-17 and tested negative affect as a possible mediator of these associations., Methods: One hundred and seventy two youths reported the extent to which they kept secrets towards parents over a period of four days. Asthma symptoms, nighttime awakenings, sleep onset latency, and subjective sleep quality were assessed with daily diaries completed by youths., Results: More frequent secret-keeping was associated with more severe asthma symptoms, lower ratings of sleep quality and greater number of nighttime awakenings. Secrecy was also associated with increased negative affect, which accounted for the associations between secrecy and number of awakenings and daytime asthma symptoms. These findings remained significant after controlling for youth age and other relevant demographic factors., Conclusions: Our findings suggest that secrecy towards parents can have consequential health outcomes for youth with asthma and point to the importance of investigating affective processes as mediators of the influence of secret-keeping on youth health., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Older adolescent and young adults (OAYA) with type 1 diabetes (T1D) living in contexts of socio-economic disadvantage (SED) suffer disproportionately from poor glycemic control and related health complications. Although SED may convey a variety of risks, it may exacerbate diabetes-related stress levels, which in turn may account for observed disparities in health outcomes. The primary goal of the present study was to investigate the relationship between subjective SED, diabetes-related perceived stress, and diurnal cortisol secretion in urban OAYA with T1D. A secondary goal was to determine if cortisol was related to measures of blood glucose (HbA1c and mean blood glucose). Analyses were conducted among OAYA ages 17-20 years (n=61) affected by T1D, who provided daily saliva samples for four days, measures of glycemic control (i.e., HbA1c and mean blood glucose assessed via Continuous Glucose Monitor), and completed psychosocial questionnaires. We found that subjective SED was associated with a flatter diurnal cortisol rhythm via diabetes-related stress. Flattened cortisol rhythm was, in turn, associated with higher levels of HbA1c, but not with mean blood glucose assessed via Continuous Glucose Monitor. These results represent some of the first empirical evidence on how distal social factors (i.e., subjective SED) and proximal psychological processes (diabetes-related perceived stress) are connected to condition-relevant biological mechanisms (i.e., elevated HbA1c), via broad biological pathways implicated in health (i.e., flatter cortisol slope)., (Copyright © 2017 Elsevier Ltd. All rights reserved.)

Physician racial bias can negatively affect Black patients' reactions to racially discordant medical interactions, suggesting that racial bias is manifested in physicians' communication with their Black patients. However, little is known about how physician racial bias actually influences their communication during these interactions. This study investigated how non-Black physicians' racial bias is related to their word use during medical interactions with Black patients. One hundred and seventeen video-recorded racially discordant medical interactions from a larger study were transcribed and analyzed using Linguistic Inquiry and Word Count (LIWC) software. Physicians with higher levels of implicit racial bias used first-person plural pronouns and anxiety-related words more frequently than physicians with lower levels of implicit bias. There was also a trend for physicians with higher levels of explicit racial bias to use first-person singular pronouns more frequently than physicians with lower levels of explicit bias. These findings suggest that non-Black physicians with higher levels of implicit racial bias may tend to use more words that reflect social dominance (i.e., first-person plural pronouns) and anxiety when interacting with Black patients.

Although research has investigated the neuroendocrine correlates of romantic relationships, the neuroendocrine correlates of friendship formation are largely unexplored. In two conditions, participants' salivary testosterone and cortisol were measured before and after a high versus low closeness activity with another same-sex participant. In the high closeness task, participants took turns answering questions that fostered increases in self-disclosure. The low closeness task fostered low levels of self-disclosure. Dyadic multilevel models indicated that lower basal testosterone and decreases in testosterone were associated with increased closeness between recently acquainted strangers. Our results suggest that people high in testosterone felt less close to others and desired less closeness. Further, lower basal cortisol and dynamic cortisol decreases were associated with greater closeness and desired closeness in the high closeness condition. Finally, we found that the partners of those who had lower cortisol desired more closeness. These findings suggest that lower testosterone and cortisol are linked to the facilitation of initial social bonds and that these social bonds may, in turn, be associated with changes in these hormones., (Copyright © 2016 Elsevier Ltd. All rights reserved.)

Although the links between marital quality and physical health are now well established, the psychological processes through which marriage impacts health remain unclear. Additionally, prior research on the links between marriage and health has focused mainly on how negative aspects of relationships (e.g., conflict, hostility) can be damaging to one's physical health. In this article, we describe the strength and strain model of marital quality and health, which provides a roadmap for studying protective factors underlying marriage-health links. We home in one relationship process-partner responsiveness-and one broad class of psychological mechanisms-affective processes-to illustrate core aspects of the model. Our review suggests that future research will profit from a greater integration of theory from the social psychology of close relationships into studies of relationships and health.

The association between the quality of people's close relationships and their physical health is well-established. But from a psychological perspective, how do close relationships impact physical health? This article summarizes recent work seeking to identify the relationship processes, psychological mediators and moderators of the links between close relationships and health, with an emphasis on studies of married and cohabitating couples. We begin with a brief review of a recent meta-analysis of the links between marital quality and health. We then describe our strength and strain model of marriage and health, homing in on one process- partner responsiveness -and one moderator- adult attachment style -to illustrate ways in which basic relationship science can inform our understanding of how relationships impact physical health. We conclude with a brief discussion of promising directions in the study of close relationships and health.

Dysregulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis and disruptions of restorative processes (e.g., sleep) have been proposed as two key mechanisms through which loneliness leads to medical morbidity in adults and late adolescents. Whether loneliness acts through these biological and behavioral intermediaries in children as well remains unexplored. In a sample of 645 children aged 8-15 affected by parental HIV/AIDS in rural China, trait and state (i.e., daily) loneliness were measured in a 3-day diary study, wherein participants also provided cortisol samples and sleep measures. Whereas high levels of trait loneliness were found to predict lower morning cortisol levels, longer time in bed, lower sleep quality, and a higher number of night awakenings, daily loneliness was associated with a flatter diurnal cortisol slope and shorter time in bed. Although the association between trait loneliness and daily loneliness with HPA activity remained significant after controlling for psychological constructs that overlap with loneliness (e.g., depression and daily negative affect), some of the associations between loneliness and sleep measures became non-significant after including these additional covariates. These findings provide the first empirical evidence to our knowledge of associations between trait and state loneliness and health-related outcomes among school-aged children and young adolescents., Competing Interests: Conflicts of Interest: None declared., (Copyright © 2016 Elsevier Ltd. All rights reserved.)

Social class is a robust predictor of health, with risk for disease and mortality increasing towards the lower end of the socioeconomic (SES) spectrum. While certain psychological characteristics, such as high sense of control, can protect low-SES individuals from adverse health outcomes, very few studies have investigated the biological mechanisms underlying these relationships. In this study, we tested whether sense of control mitigated the associations between SES and cortisol activity, and SES and physical health in daily life (i.e., number and severity of physical symptoms). Next, we tested whether individual differences in cortisol secretion would act as a mechanism by which SES and perceived control influenced physical health. In a large national sample from the Midlife in the United States (MIDUS) survey, we found that SES interacted with perceived control in predicting morning cortisol levels, cortisol slopes, number of physical symptoms, and severity of physical symptoms. Specifically, SES disparities in these health outcomes were more pronounced among individuals reporting low levels of perceived control than among individuals endorsing high levels of perceived control. Further, we found that a flatter cortisol slope mediated the link between lower SES and greater number and severity of physical symptoms for those individuals who reported lower levels of perceived control, but not for individuals reporting higher levels of perceived control. These findings suggest that perception of greater control may act as a buffer against the effect of low SES on health-related physiological processes., Competing Interests: Conflicts of Interest: None declared., (Copyright © 2016 Elsevier Ltd. All rights reserved.)

Objective: Multiple aspects of religion have been linked with a variety of physical health outcomes; however, rarely have investigators attempted to empirically test the mechanisms through which religiosity impacts health. The links between religious participation, religious coping, and diurnal cortisol patterns over a 10-year period in a national sample of adults in the United States were investigated., Method: Participants included 1,470 respondents from the Midlife in the United States (MIDUS) study who provided reports on religious participation, religious coping, and diurnal cortisol., Results: Religious participation predicted steeper ("healthier") cortisol slopes at the 10-year follow-up, controlling for potential confounds. Further, religious struggle (religious coping marked by tension and strain about religious and spiritual issues) mediated the prospective association between religious participation and cortisol slope, such that greater religious attendance predicted lower levels of religious struggle 10 years later, which in turn was linked with a steeper cortisol slope; this effect remained strong when controlling for general emotional coping and social support. Positive religious coping was unrelated to diurnal cortisol patterns., Conclusion: These findings identify religious struggle as a mechanism through which religious participation impacts diurnal cortisol levels and suggest that diurnal cortisol is a plausible pathway through which aspects of religion influence long-term physical health. (PsycINFO Database Record, ((c) 2016 APA, all rights reserved).)

Objective: Both dimensions of the work-family interface, work-to-family and family-to-work spillover, have important implications for health and well-being. Despite the importance of these associations, very little is known about the physiological mechanisms through which the interplay between family and work experiences are translated into long-lasting consequences for health., Method: This study investigated both positive and negative aspects of each spillover dimension on diurnal cortisol secretion patterns in a large panel study of working adults between the ages of 33 and 80., Results: Greater negative family-to-work (NFW) spillover predicted lower wake-up cortisol values and a flatter (less "healthy") diurnal cortisol slope. This effect was evident even after controlling for the effects of the other spillover dimensions., Conclusions: These findings indicate that not all aspects of the work-family interface might impact stress physiology to the same extent and suggest that diurnal cortisol may be an important pathway through which negative aspects of the work-family interface leave their mark on health. (PsycINFO Database Record, ((c) 2016 APA, all rights reserved).)

Objective: Living in a dangerous and disadvantaged neighborhood is consistently linked with poor health outcomes; however, few studies have investigated psychosocial mechanisms of this relationship. We hypothesized that a specific facet of depression-anhedonia-would partially explain the relationship between stressful neighborhoods and poor health in youth with asthma., Method: 156 youths provided reports on their depressive symptoms, daily asthma symptoms, and peak expiratory flow rate (PEFR). Caregivers provided reports on neighborhood characteristics., Results: Youth residing in more at-risk neighborhoods experienced more symptoms of depression, greater asthma symptoms (both during the day and night), and marginally lower PEFR. Indirect effect analyses revealed that the relationship between neighborhood stress and youth asthma symptoms was partially explained by a key symptom of depression, anhedonia., Conclusions: These findings suggest that the neighborhood-health link is partially explained by symptoms of depression tapping into difficulties experiencing pleasure and motivation., (© The Author 2016. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)

Childhood adversity is associated with poor health outcomes in adulthood; the hypothalamic-pituitary-adrenal (HPA) axis has been proposed as a crucial biological intermediary of these long-term effects. Here, we tested whether childhood adversity was associated with diurnal cortisol parameters and whether this link was partially explained by self-esteem. In both adults and youths, childhood adversity was associated with lower levels of cortisol at awakening, and this association was partially driven by low self-esteem. Further, we found a significant indirect pathway through which greater adversity during childhood was linked to a flatter cortisol slope via self-esteem. Finally, youths who had a caregiver with high self-esteem experienced a steeper decline in cortisol throughout the day compared with youths whose caregiver reported low self-esteem. We conclude that self-esteem is a plausible psychological mechanism through which childhood adversity may get embedded in the activity of the HPA axis across the life span., (© The Author(s) 2016.)

Objective: Prior work has shown that negative aspects (e.g., conflict) of marriage or marriage-like relationships are associated with poor health of offspring, but much less is known about the effects of positive aspects (e.g., affection) of parental romantic relationships. This study investigated links between conflict and affection within parents' romantic relationships and the health of youth with asthma., Method: Eighty youths with asthma aged 10-17 answered daily questions over a 4-day period about conflict and affection within their parents' romantic relationship, as well as their own daily mood, asthma symptoms, and expiratory peak flow., Results: Multiple regression analyses revealed that romantic affection-but not conflict-was directly associated with higher expiratory peak flow. Further, there was a significant indirect effect of romantic affection via youth positive affect on lower asthma symptoms., Conclusion: These results are the first to our knowledge to demonstrate that youth-reported positive characteristics of parents' romantic relationships are associated with better health among youth with asthma. (PsycINFO Database Record, ((c) 2016 APA, all rights reserved).)

Objective: The present study explored pathways from the personality traits of neuroticism and conscientiousness through health-related behaviors to diurnal patterns of the stress hormone cortisol using data from a large national study., Method: Using prospective data from the Midlife in the United States (MIDUS II) study and the National Study of Daily Experiences (NSDE II, a MIDUS substudy), hierarchical linear modeling (HLM) and Monte Carlo estimation for multilevel model mediation were used to test direct and indirect effects (via general activity level, moderate and vigorous physical activity, lifetime history of regular smoking, and alcohol consumption) of neuroticism and conscientiousness on cortisol at wakeup, diurnal cortisol slope, and cortisol awakening response (N = 960)., Results: Initial HLM models showed greater levels of conscientiousness were associated with steeper (i.e., healthier) diurnal cortisol slope. Consistent with a hypothesized indirect biobehavioral pathway, when controlling for demographic factors, cortisol-related medications, daily stressors, and positive affect, HLM models showed the relationship between conscientiousness and diurnal cortisol slope was mediated by general activity levels. Lifetime history of smoking was associated with flatter diurnal cortisol slope, but did not mediate the effect of conscientiousness on diurnal cortisol slope. No effects were found for neuroticism., Conclusions: The results support a psychophysiological model of resilience--one that provides a more complete rendering of the health-protective mechanisms of conscientiousness via hypothalamic-pituitary-adrenal axis functioning. Specifically, the mediated pathway suggests greater engagement in the activities of day-to-day life are an instrumental means by which conscientious individuals experience healthier patterns of stress hormone secretion., ((c) 2015 APA, all rights reserved).)

Objective: Living a purposeful life is associated with better mental and physical health, including longevity. Accumulating evidence shows that these associations might be explained by the association between life purpose and regulation of physiological systems involved in the stress response. The aim of this study was to investigate the prospective associations between life purpose and allostatic load over a 10-year period., Methods: Analyses were conducted using data from the Midlife in the United States (MIDUS) survey. Assessment of life purpose, psychological covariates and demographics were obtained at baseline, while biomarkers of allostatic load were assessed at the 10-year follow-up., Results: We found that greater life purpose predicted lower levels of allostatic load at follow-up, even when controlling for other aspects of psychological well-being potentially associated with allostatic load. Further, life purpose was also a strong predictor of individual differences in self-health locus of control-i.e., beliefs about how much influence individuals can exert on their own health-which, in turn, partially mediated the association between purpose and allostatic load. Although life purpose was also negatively linked to other-health locus of control-i.e., the extent to which individuals believe their health is controlled by others/chance-this association did not mediate the impact of life purpose on allostatic load., Conclusion: The current study provides the first empirical evidence for the long-term physiological correlates of life purpose and supports the hypothesis that self-health locus of control acts as one proximal psychological mechanism through which life purpose may be linked to positive biological outcomes., (Copyright © 2015. Published by Elsevier Inc.)

The association between SES and health is well established; however, only a handful of studies have investigated the relationship between SES and daily cortisol parameters. Further, within this small literature, virtually no studies have looked at psychological factors that might mitigate this relationship. In this study, we tested whether life satisfaction--the overall subjective affective assessment of one's own life--acts as a protective factor against cortisol dysregulation driven by low-SES. Among a large sample (N=1325) of individuals from the Midlife in the United States (MIDUS) survey, we found that low-SES individuals with high levels of life satisfaction had a cortisol circadian profile similar to those of high-SES individuals. In contrast, low-SES individuals reporting low life satisfaction experienced attenuated morning cortisol concentrations and a flatter ("less healthy") diurnal cortisol slope. Although more studies are needed to investigate the constellation of psychological resources and processes through which life satisfaction exerts its effects, the current work shows that the general affective evaluation of one's own life acts as a buffer against the detrimental effect of low-SES on health-related physiological processes., (Copyright © 2015 Elsevier Ltd. All rights reserved.)