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1. Effects of the FDA Codeine Safety Investigation on Racial and Geographic Disparities in Opioid Prescribing after Pediatric Tonsillectomy and/or Adenoidectomy

Author

Amy E. Lawrence, Peter C. Minneci, Sharon Wrona, Jennifer N. Cooper, Katherine J. Deans, and Deena J. Chisolm

Subjects
medicine.medical_specialty, pediatrics, medicine.medical_treatment, Opioid prescribing, 03 medical and health sciences, 0302 clinical medicine, Adenoidectomy, 030225 pediatrics, medicine, 030212 general & internal medicine, opiates, codeine, disparities, business.industry, Codeine, lcsh:RJ1-570, lcsh:Pediatrics, Tonsillectomy, Prescription opioid, Pediatrics, Perinatology and Child Health, Emergency medicine, Surgery, Original Article, black box warning, business, medicine.drug
Abstract

Objective. Our objective was to examine the impact of the U.S. FDA’s 2013 black box warning against codeine on codeine and other opioid prescription filling after pediatric tonsillectomy and/or adenoidectomy (T/A) overall and by child race and provider urbanity/rurality. Methods. Patients ≤ 18 who underwent T/A in 8/2011 to 8/2016 were identified in Ohio Medicaid claims. Interrupted time series analyses were used to evaluate the impact of the FDA warning on codeine or other opioid prescription filling post-T/A. Results. In August 2011, codeine prescription filling was lower among black than white children ( P

Published
2021

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