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9 results on '"Schneider, Gerd H."'

1. Behavioural outcomes of subthalamic stimulation and medical therapy versus medical therapy alone for Parkinson's disease with early motor complications (EARLYSTIM trial): secondary analysis of an open-label randomised trial

Author

Negovanska, Velina, Welter, Marie-Laure, Corvol, Jean-Christophe, Agid, Yves, Navarro, Soledad, Meier, Niklaus, Hartmann, Andreas, Hesekamp, Helke, Cornu, Philippe, Möller, Bettina, Nebel, Adelheid, Raethjen, Jan, Knudsen, Karina, Volkmann, Jens, Falk, Daniela, Paschen, Steffen, Meister, Ingo, Kuhn, Jens, Donner, Kerstin, Kessler, Josef, Barbe, Michael, Fink, Gereon, Maarouf, Mohammad, Kühn, Andrea, Müller, Bianca, Faust, Katharina, Gruber, Doreen, Schneider, Gerd-H., Seigneuret, Eric, Pollak, Pierre, Fraix, Valerie, Kistner, Andrea, Rascol, Olivier, Arbus, Christophe, Danet, Lola, Chaynes, Patrick, Groiss, Stefan J., Hartmann, Christian, Südmeyer, Martin, Partowinia-Peters, Mahnaz, Vesper, Jan, Ledily, Severine, Damier, Philippe, Raoul, Sylvie, Trenkwalder, Claudia, Richter-Dreske, Wenke, Wächter, Tobias, Weiss, Daniel, Eusebio, Alexandro, Azulay, Jean Philippe, Polo, Gustavo, Pinto, Serge, Levin, Johannes, Dornier, Stephanie, Pene, Fredy, Hourton, Delphine, Quintin, Mathieu, Hoffart-Jourdain, Cecile, Brocvielle, Helene, Balthasar, Kerstin, Stein, Meryem, Harnisch, Susanne, Reuss, Alexander, Aminossadati, Behnaz, Nasemann, Christian, Oertel, Wolfgang, Bataille, Benoit, Hellwig, Dieter, Gharabaghi, Alireza, Amtage, Florian, Mertens, Patrick, Kloss, Manja, Post, Bart, Speelman, Hans, Lhommée, Eugénie, Wojtecki, Lars, Czernecki, Virginie, Witt, Karsten, Maier, Franziska, Tonder, Lisa, Timmermann, Lars, Hälbig, Thomas D, Pineau, Fanny, Durif, Franck, Witjas, Tatiana, Pinsker, Marcus, Mehdorn, Maximilian, Sixel-Döring, Friederike, Kupsch, Andreas, Krüger, Rejko, Elben, Saskia, Chabardès, Stephan, Thobois, Stéphane, Brefel-Courbon, Christine, Ory-Magne, Fabienne, Regis, Jean-Marie, Maltête, David, Sauvaget, Anne, Rau, Jörn, Schnitzler, Alfons, Schüpbach, Michael, Schade-Brittinger, Carmen, Deuschl, Gunther, Houeto, Jean-Luc, and Krack, Paul

Published
2018
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2. Quality of life predicts outcome of deep brain stimulation in early Parkinson disease

Author

Schuepbach, W.M. Michael, Tonder, Lisa, Schnitzler, Alfons, Krack, Paul, Rau, Joern, Hartmann, Andreas, Hälbig, Thomas, Pineau, Fanny, Falk, Andrea, Paschen, Laura, Paschen, Stephen, Volkmann, Jens, Dafsari, Haidar S., Barbe, Michael T., Fink, Gereon R., Kühn, Andrea, Kupsch, Andreas, Schneider, Gerd-H., Seigneuret, Eric, Fraix, Valerie, Kistner, Andrea, Chaynes, P. Patrick, Ory-Magne, Fabienne, Brefel-Courbon, Christine, Vesper, Jan, Wojtecki, Lars, Derrey, Stéphane, Maltête, David, Damier, Philippe, Derkinderen, Pascal, Sixel-Döring, Friederike, Trenkwalder, Claudia, Gharabaghi, Alireza, Wächter, Tobias, Weiss, Daniel, Pinsker, Marcus O., Regis, Jean-Marie, Witjas, Tatiana, Thobois, Stephane, Mertens, Patrick, Knudsen, Karina, Schade-Brittinger, Carmen, Houeto, Jean-Luc, Agid, Yves, Vidailhet, Marie, Timmermann, Lars, and Deuschl, Günther

Published
2019
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6. Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: Results from a prospective, randomized sham-controlled trial

Author

Mueller, Joerg, Skogseid, Inger M., Benecke, Reiner, Kupsch, Andreas, Trottenberg, Thomas, Poewe, Werner, Schneider, Gerd H., Eisner, Wilhelm, Wolters, Alexander, Müller, J. U., Deuschl, Günther, Pinsker, Marcus O., Roeste, Geir K., Vollmer-Haase, Juliane, Brentrup, Angela, Krause, Martin, Tronnier, Volker, Schnitzler, Alfons, Voges, Jüergen, Nikkhah, Guido, Vesper, Jan, Naumann, Markus, and Volkmann, Jens

Published
2008
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8. Intraoperative frozen section fails to improve diagnostic accuracy in stereotactic biopsies but doubles procedure length - results of a prospective randomized study

Author

Misch, Martin, Schneider, Gerd-H., Koch, Arend, Prall, Friedrich, Vajkoczy, Peter, and Stockhammer, Florian

Subjects
ddc: 610, prospective trial, 610 Medical sciences, Medicine, stereotaxy, frozen section
Abstract

Objective: Frame-based stereotactic biopsy has high technical standards, high diagnostic accuracy and a very precise target point definition due to multimodal image integration. However, intraoperative frozen section is considered the “gold standard” in this procedure. Omitting frozen [for full text, please go to the a.m. URL], 65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Published
2014
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9. Quality of life predicts outcome of deep brain stimulation in early Parkinson disease

Author

Schüpbach, Michael, Tonder, Lisa, Schnitzler, Alfons, Krack, Paul, Rau, Joern, Hartmann, Andreas, Hälbig, Thomas D, Pineau, Fanny, Falk, Andrea, Paschen, Laura, Paschen, Stephen, Volkmann, Jens, Dafsari, Haidar S, Barbe, Michael T, Fink, Gereon R, Kühn, Andrea, Kupsch, Andreas, Schneider, Gerd-H, Seigneuret, Eric, Fraix, Valerie, Kistner, Andrea, Chaynes, P Patrick, Ory-Magne, Fabienne, Brefel-Courbon, Christine, Vesper, Jan, Wojtecki, Lars, Derrey, Stéphane, Maltête, David, Damier, Philippe, Derkinderen, Pascal, Sixel-Döring, Friederike, Trenkwalder, Claudia, Gharabaghi, Alireza, Wächter, Tobias, Weiss, Daniel, Pinsker, Marcus O, Regis, Jean-Marie, Witjas, Tatiana, Thobois, Stephane, Mertens, Patrick, Knudsen, Karina, Schade-Brittinger, Carmen, Houeto, Jean-Luc, Agid, Yves, Vidailhet, Marie, Timmermann, Lars, and Deuschl, Günther

Subjects
10. No inequality, 610 Medicine & health, humanities, nervous system diseases, 3. Good health
Abstract

OBJECTIVE To investigate predictors for improvement of disease-specific quality of life (QOL) after deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson disease (PD) with early motor complications. METHODS We performed a secondary analysis of data from the previously published EARLYSTIM study, a prospective randomized trial comparing STN-DBS (n = 124) to best medical treatment (n = 127) after 2 years follow-up with disease-specific QOL (39-item Parkinson's Disease Questionnaire summary index [PDQ-39-SI]) as the primary endpoint. Linear regression analyses of the baseline characteristics age, disease duration, duration of motor complications, and disease severity measured at baseline with the Unified Parkinson's Disease Rating Scale (UPDRS) (UPDRS-III "off" and "on" medications, UPDRS-IV) were conducted to determine predictors of change in PDQ-39-SI. RESULTS PDQ-39-SI at baseline was correlated to the change in PDQ-39-SI after 24 months in both treatment groups (p < 0.05). The higher the baseline score (worse QOL) the larger the improvement in QOL after 24 months. No correlation was found for any of the other baseline characteristics analyzed in either treatment group. CONCLUSION Impaired QOL as subjectively evaluated by the patient is the most important predictor of benefit in patients with PD and early motor complications, fulfilling objective gold standard inclusion criteria for STN-DBS. Our results prompt systematically including evaluation of disease-specific QOL when selecting patients with PD for STN-DBS. CLINICALTRIALSGOV IDENTIFIER NCT00354133.

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