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537 results on '"Schäfer, Markus"'

16. Neoadjuvant Chemoradiotherapy Versus Chemotherapy for the Treatment of Locally Advanced Esophageal Adenocarcinoma in the European Multicenter ENSURE Study

Author

Elliott, Jessie A., Klevebro, Fredrik, Mantziari, Styliani, Markar, Sheraz R., Goense, Lucas, Johar, Asif, Lagergren, Pernilla, Zaninotto, Giovanni, van Hillegersberg, Richard, van Berge Henegouwen, Mark I., Schäfer, Markus, Nilsson, Magnus, Hanna, George B., Reynolds, John V., Van Veer, Hans, Depypere, Lieven, Coosemans, Willy, Nafteux, Philippe, Carroll, Paul, Allison, Frances, Darling, Gail, Findlay, John M, Everden, Serenydd, Maynard, Nicholas D, Ariyarathenam, Arun, Sanders, Grant, Jaunoo, Shameen, Singh, Pritam, Parsons, Simon, Saunders, John, Vohra, Ravinder, Sinha, Aaditya, Tan, Benjamin HL., Whiting, John G, Boshier, Piers R, Phillips, Alexander W, Griffin, S Michael, Walker, Robert C., Underwood, Tim J, Piessen, Guillaume, Theisen, Jorg, Friess, Hans, Bruns, Christiane J., Schröder, Wolfgang, Collins, Chris G, McAnena, Oliver J, Rooney, Siobhan, Quinn, Aoife, Toale, Conor, Murphy, Thomas J, Ravi, Narayanasamy, Donohoe, Claire L, Scarpa, Marco, Bardini, Romeo, Degasperi, Silvia, Saadeh, Luca, Castoro, Carlo, Alfieri, Rita, Pinto, Eleonora, Mattara, Genny, Kalff, Marianne C, Gisbertz, Suzanne S, Berge Henegouwen, Mark I Van, van Hootegem, Sander JM, Lagarde, Sjoerd M, Lanschot, J Jan B van, Kingma, B Feike, Rurrda, Jelle P, van Hillegersberg, Richard, Kennedy, Raymond, Carey, P. Declan, Prodehl, Leanne, Lamb, Peter J, Skipworth, Richard JE, Cero, Mariagiulia Dal, Pera, Manuel, Huang, Biying, Linder, Gustav, Sundbom, Magnus, Mantziari, Styliani, Schäfer, Markus, and Demartines, Nicolas

Published
2023
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18. Reliability assessment of composite column according to Monte Carlo Simulation and Latin Hypercube Sampling

Author

Zogu Pellumb and Schäfer Markus

Subjects
Environmental sciences, GE1-350
Abstract

When a structural element, like a column, is evaluated for resistance using the finite element method or analytical calculation, all parameters related to the resistance side and action effect are treated as deterministic. Nevertheless, in probabilistic analyses, these parameters are regarded as random variables, which are defined using various distributions like the normal distribution, log-normal distribution, beta, or gamma distribution. Monte Carlo Simulation (MCS) and Latin Hypercube Sampling (LHS) are two sampling methods widely used for generating random samples from statistical distribution. The number of samples generated influences the accuracy of the sampling methods especially the Monte Carlo Simulation; generally speaking, the more samples generated, the more accurate the results and this also implies a significant amount of work and computation time. Consequently, the purpose of this paper is to compare the two sampling methods for the reliability assessment of the resistance of the composite column to flexural buckling under compression force.

Published
2024
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19. Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe

Author

Rozema, Tom, Heisterkamp, Joos, Schaefer, Markus, Ozsahin, Esat-Mahmut, de Haan, Jacco, Willem van den Berg, Jan, Duprez, Frederic, Callebout, Eduard, van Daele, Elke, Hacker, Ulrich, Hoffmeister, Albrecht, Kuhnt, Thomas, Denecke, Timm, Kluge, Regine, Prager, Gerald, Ilhan-Mutlu, A., Cuicchi, Dajana, Ardizzoni, Andrea, Rosman, Camiel, Gootjes, Elske C., Rütten, Heidi, Puccetti, Francesco, Cascinu, Stefano, Slim, Najla, Barrios, Maria Eugenia, Fernandez, Maria Carmen, Martí-Oriol, Roberto, Alvaro, Marisol Huerta, Vera, Almudena, Jordá, Esther, Mozos, Fernando L., Reig, Anna, Visa, Laura, Ciseł, Bogumiła, Czechowska, Joanna, Kwietniewska, Magdalena, Pikuła, Agnieszka, Skórzewska, Magdalena, Kozłowska, Aleksandra, Rawicz-Pruszyński, Karol, Kroese, Tiuri E., van Laarhoven, Hanneke W.M., Schoppman, Sebastian F., Deseyne, Pieter R.A.J., van Cutsem, Eric, Haustermans, Karin, Nafteux, Philippe, Thomas, Melissa, Obermannova, Radka, Mortensen, Hanna R., Nordsmark, Marianne, Pfeiffer, Per, Elme, Anneli, Adenis, Antoine, Piessen, Guillaume, Bruns, Christiane J., Lordick, Florian, Gockel, Ines, Moehler, Markus, Gani, Cihan, Liakakos, Theodore, Reynolds, John, Morganti, Alessio G., Rosati, Riccardo, Castoro, Carlo, Cellini, Francesco, D'Ugo, Domenico, Roviello, Franco, Bencivenga, Maria, de Manzoni, Giovanni, van Berge Henegouwen, Mark I., Hulshof, Maarten C.C.M., van Dieren, Jolanda, Vollebergh, Marieke, van Sandick, Johanna W., Jeene, Paul, Muijs, Christel T., Slingerland, Marije, Voncken, Francine E.M., Hartgrink, Henk, Creemers, Geert-Jan, van der Sangen, Maurice J.C., Nieuwenhuijzen, Grard, Berbee, Maaike, Verheij, Marcel, Wijnhoven, Bas, Beerepoot, Laurens V., Mohammad, Nadia H., Mook, Stella, Ruurda, Jelle P., Kolodziejczyk, Piotr, Polkowski, Wojciech P., Wyrwicz, Lucjan, Alsina, Maria, Pera, Manuel, Kanonnikoff, Tania F., Cervantes, Andrés, Nilsson, Magnus, Monig, Stefan, Wagner, Anna D., Guckenberger, Matthias, Griffiths, Ewen A., Smyth, Elizabeth, Hanna, George B., Markar, Sheraz, Chaudry, M. Asif, Hawkins, Maria A., Cheong, Edward, van Hillegersberg, Richard, and van Rossum, Peter S.N.

Published
2023
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23. An International Multicenter Study Exploring Whether Surveillance After Esophageal Cancer Surgery Impacts Oncological and Quality of Life Outcomes (ENSURE)

Author

Elliott, Jessie A., Markar, Sheraz R., Klevebro, Fredrik, Johar, Asif, Goense, Lucas, Lagergren, Pernilla, Zaninotto, Giovanni, van Hillegersberg, Richard, van Berge Henegouwen, Mark I., Nilsson, Magnus, Hanna, George B., Reynolds, John V., Van Veer, Hans, Depypere, Lieven, Coosemans, Willy, Nafteux, Philippe, Carroll, Paul, Allison, Frances, Darling, Gail, Findlay, John M, Everden, Serenydd, Maynard, Nicholas D, Ariyarathenam, Arun, Sanders, Grant, Jaunoo, Shameen, Singh, Pritam, Parsons, Simon, Saunders, John, Vohra, Ravinder, Sinha, Aaditya, HLTan, Benjamin, Whiting, John G, Boshier, Piers R, Phillips, Alexander W, Griffin, S Michael, Walker, Robert C, Underwood, Tim J, Piessen, Guillaume, Theisen, Jorg, Friess, Hans, Bruns, Christiane J, Schröder, Wolfgang, Collins, Chris G, McAnena, Oliver J, Rooney, Siobhan, Quinn, Aoife, Toale, Conor, Murphy, Thomas J, Ravi, Narayanasamy, Donohoe, Claire L, Scarpa, Marco, Bardini, Romeo, Degasperi, Silvia, Saadeh, Luca, Castoro, Carlo, Alfieri, Rita, Pinto, Eleonora, Mattara, Genny, Kalff, Marianne C, Gisbertz, Suzanne S, Van Berge Henegouwen, Mark I, van Hootegem, Sander JM, Lagarde, Sjoerd M, Wijnhoven, Bas PL, van Lanschot, J Jan B, Kingma, B Feike, Rurrda, Jelle P, van Hillegersberg, Richard, Kennedy, Raymond, Carey, P Declan, Prodehl, Leanne, Lamb, Peter J, Skipworth, Richard JE, Cero, Mariagiulia Dal, Pera, Manuel, Huang, Biying, Linder, Gustav, Sundbom, Magnus, Mantziari, Styliani, Schäfer, Markus, Allemann, Pierre, and Demartines, Nicolas

Published
2023
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32. In silico approaches in organ toxicity hazard assessment: Current status and future needs for predicting heart, kidney and lung toxicities

Author

Bassan, Arianna, Alves, Vinicius M., Amberg, Alexander, Anger, Lennart T., Beilke, Lisa, Bender, Andreas, Bernal, Autumn, Cronin, Mark T.D., Hsieh, Jui-Hua, Johnson, Candice, Kemper, Raymond, Mumtaz, Moiz, Neilson, Louise, Pavan, Manuela, Pointon, Amy, Pletz, Julia, Ruiz, Patricia, Russo, Daniel P., Sabnis, Yogesh, Sandhu, Reena, Schaefer, Markus, Stavitskaya, Lidiya, Szabo, David T., Valentin, Jean-Pierre, Woolley, David, Zwickl, Craig, and Myatt, Glenn J.

Published
2021
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33. In silico approaches in organ toxicity hazard assessment: Current status and future needs in predicting liver toxicity

Author

Bassan, Arianna, Alves, Vinicius M., Amberg, Alexander, Anger, Lennart T., Auerbach, Scott, Beilke, Lisa, Bender, Andreas, Cronin, Mark T.D., Cross, Kevin P., Hsieh, Jui-Hua, Greene, Nigel, Kemper, Raymond, Kim, Marlene T., Mumtaz, Moiz, Noeske, Tobias, Pavan, Manuela, Pletz, Julia, Russo, Daniel P., Sabnis, Yogesh, Schaefer, Markus, Szabo, David T., Valentin, Jean-Pierre, Wichard, Joerg, Williams, Dominic, Woolley, David, Zwickl, Craig, and Myatt, Glenn J.

Published
2021
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37. Sex-related differences in oncologic outcomes, operative complications and health-related quality of life after curative-intent oesophageal cancer treatment: multicentre retrospective analysis.

Author

Mantziari, Styliani, Elliott, Jessie A, Markar, Sheraz R, Klevebro, Fredrik, Goense, Lucas, Johar, Asif, Lagergren, Pernilla, Zaninotto, Giovanni, Hillegersberg, Richard van, Henegouwen, Mark I van Berge, Schäfer, Markus, Nilsson, Magnus, Hanna, George B, Reynolds, John V, and Group, ENSURE Study

Subjects
ESOPHAGEAL cancer, QUALITY of life, PATIENTS, SQUAMOUS cell carcinoma, CANCER treatment
Abstract

Background Oesophageal cancer, in particular adenocarcinoma, has a strong male predominance. However, the impact of patient sex on operative and oncologic outcomes and recovery of health-related quality of life is poorly documented, and was the focus of this large multicentre cohort study. Methods All consecutive patients who underwent oncological oesophagectomy from 2009 to 2015 in the 20 European iNvestigation of SUrveillance after Resection for Esophageal cancer study group centres were assessed. Clinicopathologic variables, therapeutic approach, postoperative complications, survival and health-related quality of life data were compared between male and female patients. Multivariable analyses adjusted for age, sex, tumour histology, treatment protocol and major complications. Specific subgroup analyses comparing adenocarcinoma versus squamous cell cancer for all key outcomes were performed. Results Overall, 3974 patients were analysed, 3083 (77.6%) male and 891 (22.4%) female; adenocarcinoma was predominant in both groups, while squamous cell cancer was observed more commonly in female patients (39.8% versus 15.1%, P < 0.001). Multivariable analysis demonstrated improved outcomes in female patients for overall survival (HRmales 1.24, 95% c.i. 1.07 to 1.44) and disease-free survival (HRmales 1.22, 95% c.i. 1.05 to 1.43), which was caused by the adenocarcinoma subgroup, whereas this difference was not confirmed in squamous cell cancer. Male patients presented higher health-related quality of life functional scores but also a higher risk of financial problems, while female patients had lower overall summary scores and more persistent gastrointestinal symptoms. Conclusion This study reveals uniquely that female sex is associated with more favourable long-term survival after curative treatment for oesophageal cancer, especially adenocarcinoma, although long-term overall and gastrointestinal health-related quality of life are poorer in women. [ABSTRACT FROM AUTHOR]

Published
2024
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