Search

Background and aims: Gingivitis in orthodontic treatment remains a challenging and undesirable consequence of orthodontic treatment. Hence, a variety of chemical or herbal agents, methods, and techniques have been investigated to prevent or reduce gingivitis that occurs in orthodontic treatment. In this study, we will evaluate and compare the effect of curcumin (CMN) gel with chlorhexidine (CHX) gel on clinical parameters (plaque and gingival index) and oral bacterial number (total bacterial count test) in fixed orthodontic patients that have gingivitis. We are the first to use curcumin gel for patients that have gingivitis with fixed orthodontic appliances. Samples and Methods: Forty-five patients with fixed orthodontic appliances with metallic brackets that have generalized chronic dental plaque-induced gingivitis were selected randomly and divided into three groups - Group I (control), Group II (CMN), and Group III (CHX), respectively. Clinical parameters which are plaque index (PI) and gingival index (GI) were recorded at the baseline, 14 days, and 21 days of treatment, and a total bacterial count test (TBCT) was done for all the participants before and after treatment. Results: Both Curcumin and Chlorhexidine gel groups showed a significant reduction (P0.05). Conclusion: The results of this study show that curcumin and chlorhexidine gel have comparable anti-plaque, anti-gingivitis, and antibacterial activities and that both can be used to effectively treat plaque-induced gingivitis.

Prader-Willi syndrome (PWS) is a genetic disorder described by multifaceted clinical features with implications on the endocrine system, metabolism, and behavior. Some symptoms of PWS syndrome can be confused with the relative clinical aspects of hypothyroidism, such as lethargy, muscular hypotonia, and poor sucking ability. In this review, we would like to enlighten the importance of checking thyroid function in PWS patients at birth, at least annually, in those on growth hormone (GH) treatment, in any child of PWS with growth failure, and in those in whom there is an insufficient response to GH therapy, to ensure that any aberrant thyroid function is not overlooked and adequately treated.