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Summary: Background: While many patients seem to recover from SARS-CoV-2 infections, many patients report experiencing SARS-CoV-2 symptoms for weeks or months after their acute COVID-19 ends, even developing new symptoms weeks after infection. These long-term effects are called post-acute sequelae of SARS-CoV-2 (PASC) or, more commonly, Long COVID. The overall prevalence of Long COVID is currently unknown, and tools are needed to help identify patients at risk for developing long COVID. Methods: A working group of the Rapid Acceleration of Diagnostics-radical (RADx-rad) program, comprised of individuals from various NIH institutes and centers, in collaboration with REsearching COVID to Enhance Recovery (RECOVER) developed and organized the Long COVID Computational Challenge (L3C), a community challenge aimed at incentivizing the broader scientific community to develop interpretable and accurate methods for identifying patients at risk of developing Long COVID. From August 2022 to December 2022, participants developed Long COVID risk prediction algorithms using the National COVID Cohort Collaborative (N3C) data enclave, a harmonized data repository from over 75 healthcare institutions from across the United States (U.S.). Findings: Over the course of the challenge, 74 teams designed and built 35 Long COVID prediction models using the N3C data enclave. The top 10 teams all scored above a 0.80 Area Under the Receiver Operator Curve (AUROC) with the highest scoring model achieving a mean AUROC of 0.895. Included in the top submission was a visualization dashboard that built timelines for each patient, updating the risk of a patient developing Long COVID in response to clinical events. Interpretation: As a result of L3C, federal reviewers identified multiple machine learning models that can be used to identify patients at risk for developing Long COVID. Many of the teams used approaches in their submissions which can be applied to future clinical prediction questions. Funding: Research reported in this RADx® Rad publication was supported by the National Institutes of Health. Timothy Bergquist, Johanna Loomba, and Emily Pfaff were supported by Axle Subcontract: NCATS-STSS-P00438.

The National Clinical Cohort Collaborative (N3C) uses privacy-preserving record linkage (PPRL) to formulate longitudinal patient histories and for de-duplication across disparate data including electronic health records, administrative claims, and mortality data. The N3C employs a linkage honest broker implementation model which separates the entity holding de-identified PPRL tokens, from the entity holding the substantive data payloads. As a result of this data governance structure, linkage quality assessments are necessarily distributed into 2 distinct processes: 1) Linkage Honest Broker receipt and processing of linkages, 2) Data Aggregation entity assembling data based on received linkage crosswalks. Data is released on a weekly basis. This presentation will focus on Step 2 for the Mortality data linkages where the downstream data linkage pipelines must assess linkage quality across several dimensions of quality, focused on plausibility. There are 4 types of mortality data spanning the electronic health record, government Social Security Administration death master files, third-party obituary data, and administrative claims. Each of these sources has different levels of authoritativeness and data latency, compounding the challenges of reconciling fact of death including accurate death reporting dates. To address these challenges, we implemented an automated linkage quality pipeline which generates reports that assess linkage plausibility across the various data types, classifying concordance and discordance between data sources including age, dates of death, surfacing plausible and non-plausible activities post-death. Sharing our real-world implementation will aid conference attendees in understanding how to plan for such activities when considering specific implementation models for privacy-preserving linkages.

Data centralization is increasingly non-viable in the changing landscape of data privacy and data governance. New models of data sharing are needed, in particular when privacy-preserving record linkages (PPRL) are being used to connect data within restricted data enclaves and public open enclaves. We share a privacy-preserving data-sharing infrastructure that employs a linkage honest broker implementation of PPRL connecting structured electronic health record data between the National Center for Advancing Translational Science (NCATS) National Clinical Cohort Collaborative (N3C), a restricted data enclave, with the National Cancer Institute (NCI) Cancer Imaging Archive (TCIA), a public open enclave. In particular we will address: • Data governance models needed when linking data from restricted vs. public enclaves • Specific privacy-preserving consideration when linking to imaging data which contain specific structured data and imaging considerations • Privacy-preserving data aggregation when combining multi-modal data from restricted data enclaves with publicly discoverable imaging data

Abstract Combination of anti-cancer drugs is broadly seen as way to overcome the often-limited efficacy of single agents. The design and testing of combinations are however very challenging. Here we present a uniquely large dataset screening over 5000 targeted agent combinations across 81 non-small cell lung cancer cell lines. Our analysis reveals a profound heterogeneity of response across the tumor models. Notably, combinations very rarely result in a strong gain in efficacy over the range of response observable with single agents. Importantly, gain of activity over single agents is more often seen when co-targeting functionally proximal genes, offering a strategy for designing more efficient combinations. Because combinatorial effect is strongly context specific, tumor specificity should be achievable. The resource provided, together with an additional validation screen sheds light on major challenges and opportunities in building efficacious combinations against cancer and provides an opportunity for training computational models for synergy prediction.

Transepithelial electrical resistance (TEER) is a widely used technique for quantifying the permeability of epithelial and endothelial cell layers. However, traditional methods of measuring TEER are limited to single timepoint measurements and can subject cells to an altered environment during the measurement. Here, we assessed the validity of TEER measurements by the ECIS TEER96 device, which is designed to take continuous TEER measurements of a cell culture system in a standard laboratory incubator. We found that the instrument accurately measures TEER across TEER values ranging from 10 to 2050 Ω*cm2 and is more accurate than the manual epithelial voltohmmeter electrode at high TEER values. Furthermore, the high-resolution measurements provided by the device allowed for a unique insight into the mechanisms and kinetics of cells in vitro. To demonstrate the continuous measurement capability of the device, we tracked the formation of an MDCKI cell monolayer until TEER plateaued. Furthermore, we treated Caco-2 monolayers with different concentrations of DMSO and the antimicrobial and surfactant compound benzethonium chloride to measure disruptions to barrier integrity. Treatment of both compounds resulted in concentration-dependent loss of barrier integrity. Our results suggest that the ECIS TEER96 device is a reliable and convenient option for measuring TEER in cell cultures and can provide valuable insights into the behavior of cells in vitro. This technology will be especially useful for increasing throughput of drug permeability assays, inflammation studies, and gaining better understanding of disease states in a cell culture system.

Abstract Background Multi-institution electronic health records (EHR) are a rich source of real world data (RWD) for generating real world evidence (RWE) regarding the utilization, benefits and harms of medical interventions. They provide access to clinical data from large pooled patient populations in addition to laboratory measurements unavailable in insurance claims-based data. However, secondary use of these data for research requires specialized knowledge and careful evaluation of data quality and completeness. We discuss data quality assessments undertaken during the conduct of prep-to-research, focusing on the investigation of treatment safety and effectiveness. Methods Using the National COVID Cohort Collaborative (N3C) enclave, we defined a patient population using criteria typical in non-interventional inpatient drug effectiveness studies. We present the challenges encountered when constructing this dataset, beginning with an examination of data quality across data partners. We then discuss the methods and best practices used to operationalize several important study elements: exposure to treatment, baseline health comorbidities, and key outcomes of interest. Results We share our experiences and lessons learned when working with heterogeneous EHR data from over 65 healthcare institutions and 4 common data models. We discuss six key areas of data variability and quality. (1) The specific EHR data elements captured from a site can vary depending on source data model and practice. (2) Data missingness remains a significant issue. (3) Drug exposures can be recorded at different levels and may not contain route of administration or dosage information. (4) Reconstruction of continuous drug exposure intervals may not always be possible. (5) EHR discontinuity is a major concern for capturing history of prior treatment and comorbidities. Lastly, (6) access to EHR data alone limits the potential outcomes which can be used in studies. Conclusions The creation of large scale centralized multi-site EHR databases such as N3C enables a wide range of research aimed at better understanding treatments and health impacts of many conditions including COVID-19. As with all observational research, it is important that research teams engage with appropriate domain experts to understand the data in order to define research questions that are both clinically important and feasible to address using these real world data.

Effective small molecule therapies to combat the SARS-CoV-2 infection are still lacking as the COVID-19 pandemic continues globally. High throughput screening assays are needed for lead discovery and optimization of small molecule SARS-CoV-2 inhibitors. In this work, we have applied viral pseudotyping to establish a cell-based SARS-CoV-2 entry assay. Here, the pseudotyped particles (PP) contain SARS-CoV-2 spike in a membrane enveloping both the murine leukemia virus (MLV) gag-pol polyprotein and luciferase reporter RNA. Upon addition of PP to HEK293-ACE2 cells, the SARS-CoV-2 spike protein binds to the ACE2 receptor on the cell surface, resulting in priming by host proteases to trigger endocytosis of these particles, and membrane fusion between the particle envelope and the cell membrane. The internalized luciferase reporter gene is then expressed in cells, resulting in a luminescent readout as a surrogate for spike-mediated entry into cells. This SARS-CoV-2 PP entry assay can be executed in a biosafety level 2 containment lab for high throughput screening. From a collection of 5,158 approved drugs and drug candidates, our screening efforts identified 7 active compounds that inhibited the SARS-CoV-2-S PP entry. Of these seven, six compounds were active against live replicating SARS-CoV-2 virus in a cytopathic effect assay. Our results demonstrated the utility of this assay in the discovery and development of SARS-CoV-2 entry inhibitors as well as the mechanistic study of anti-SARS-CoV-2 compounds. Additionally, particles pseudotyped with spike proteins from SARS-CoV-2 B.1.1.7 and B.1.351 variants were prepared and used to evaluate the therapeutic effects of viral entry inhibitors.

Athlete maltreatment has become 'one of the greatest concerns faced by governing bodies, authorities and practitioners in sport' (Stirling 2009, p. 1901). Its causes broadly stem from: (1) the culture and authority structures in organised sport; (2) the limited legal rights of athletes; and (3) a fragmented system of organisational oversight. Cutting across these causes is the distinct 'policy mix' within the elite sport system itself. Drawing upon a theoretical framework located within 'new institutionalism' and an interpretive qualitative approach using document analysis and semi-structured interviews, this investigation focuses on how policy instruments (e.g. programmes, rules, budgets, etc.) combine to shape/reinforce the behaviour and views of athletes, coaches, and administrators. Findings show that the policy instruments within the existing hierarchical structure of the elite sport system are interconnected and complement each other to mutually facilitate the attainment of elite sport success. Overall, this study suggests that the mix of policy instruments aimed at achieving the state's sport/political objectives may sustain and reinforce maltreatment. [ABSTRACT FROM AUTHOR]

Wellbeing has firmly established itself within contemporary practice, politics and policy. Indeed, the cultural, commercial, and terrestrial landscape of the concept is staggering and manifests within popular discourse and across global organisations and institutions, national governments, workplaces, and consumer lifestyle products and services. Notably, the field of sport, exercise, and physical activity has been identified by the World Health Organisation (WHO), the United Nations, and the OECD as a key sector with the potential to contribute to people's wellbeing. This should not be surprising given that there is a large body of literature espousing the benefits of regular physical activity (in myriad forms) as part of a healthy lifestyle. However, there are increasing concerns that wellbeing's global ubiquity may be leading to a range of unintended consequences and/or unscrupulous practices within both international organisations and nation-states. This largely conceptual essay focuses on the concept and process of wellbeing washing by (1) tracing the historical roots and evolution of wellbeing; (2) exploring its reconceptualization within the framework of neoliberalism; (3) offering a preliminary outline of the concept of wellbeing washing; and (4) briefly describing how wellbeing washing is manifesting within the context of sport in Aotearoa/New Zealand. Overall, this analysis explores wellbeing as a contested terrain of interests marked by a range of complexities and contradictions. [ABSTRACT FROM AUTHOR]

Athlete maltreatment in organized sport has attracted considerable attention from governing bodies, stakeholders and the general public. Despite numerous studies and policy proposals from various countries, the problem remains unresolved due to its inherent complexity. Drawing upon the concept of 'a wicked problem' widely utilized in policy analysis, this study first identifies the wicked features of maltreatment, focusing on: (1) the difficulty of establishing a definition of maltreatment; (2) the challenges of identifying its causes; and (3) the impediments to identifying solutions in a context of embedded stakeholders and unintended consequences. To provide further analysis, we compare athlete maltreatment with other issues in sport such as doping and match-fixing, to suggest that lessons can be drawn from other wicked problems in the same contested terrain. Overall, given the complex interplay between maltreatment and the maintenance/legitimization of sport systems, this paper calls for continuing attention and evaluation of existing research/policies and advocates for a more multidimensional view that acknowledges maltreatment as a wicked problem. [ABSTRACT FROM AUTHOR]

Understanding the infection parameters and host responses against SARS-CoV-2 require data from large cohorts using standardized methods. Here, the authors optimize a serum ELISA protocol that has minimal cross-reactivity and flexible sample collection workflow in an attempt to standardize data generation and help inform on COVID-19 pandemic and immunity.

This study considers the reforms of Chile's state sport structures from 2001 to 2022. Drawing upon institutional frameworks, the purpose of this article is to analyse the emerging rules, practices and narratives from these reforms. This study employed a qualitative approach, with data gathered from document analysis and semi-structured interviews with six policymakers/bureaucrats from the Ministry of Sport (MINDEP) and National Institute of Sport (IND). Data was analysed through thematic coding of available texts (e.g. policies, government documentation, media sources and interview transcripts) via MAXQDA 2022 qualitative analysis software. The findings highlight that incommensurate rules, practices and narratives may be the impetus for institutional change. Rules connected with New Public Management (NPM) and the creation of the National Institute of Sport (Law 19.712 of 2001) conflicted with the discretionary practices of previous institutional arrangements. Subsequent legislation created a (rule-based) dichotomy between 'thinkers' (MINDEP) and 'doers' (IND), which has been influenced by the practice of politically based appointments into the IND. While informants suggested that the system's parochialism and incapacity render change unlikely in the future, there is nevertheless evidence of change emanating from the combination of broken rules (in the form of scandals), incommensurate practices and contemporary narratives about the need to engage with communities. [ABSTRACT FROM AUTHOR]

On 17th May 2020, the New Zealand Government announced a $265 million investment to support sport and recreation amid the country's first COVID-19 lockdown. The Sport NZ Recovery Package (RP) focused on three investment outcomes for the sector: 'Reset and Rebuild', 'Strengthen and Adapt', and [become] 'Different and Better' (Sport NZ 2020a). This study examines the overall design features and funding initiatives of the RP as a novel policy response to 'turbulence'. Of particular interest is whether this instrument was 'system changing' (McDonnell and Elmore 1987) and how it might enable future transformation or stability in the sports sector. Drawing from documents and interviews with officials from Sport NZ, one National Sports Organisation (NSO), and six Regional Sports Trusts (RSTs), three key findings relate to 1) the characteristics of the RP as policy instrument; 2) the novelty of Tū Manawa relative to Sport NZ's shifting strategy; and 3) the way in which organisations coped with the administration of new funds. The findings suggest that Sport NZ's funding strategies were multidimensional (targeting a wider array of activities and organisations than those pre-COVID-19) and could themselves be 'turbulent-inducing'. Future studies should examine the long-term legacy of the package and its associated goals to interpret if Sport NZ's initiatives are sustained for the [promised] readjustment and strengthening of the New Zealand sports sector. [ABSTRACT FROM AUTHOR]

In the fall of 2014, an international news agency reported that patients suffering from Ebola virus disease (EVD) in Liberia were treated successfully with lamivudine, an antiviral drug used to treat human immunodeficiency virus-1 and hepatitis B virus infections. According to the report, 13 out of 15 patients treated with lamivudine survived and were declared free from Ebola virus disease. In this study, the anti-Ebola virus (EBOV) activity of lamivudine and another antiretroviral, zidovudine, were evaluated in a diverse set of cell lines against two variants of wild-type EBOV. Variable assay parameters were assessed to include different multiplicities of infection, lengths of inoculation times, and durations of dosing. At a multiplicity of infection of 1, lamivudine and zidovudine had no effect on EBOV propagation in Vero E6, Hep G2, or HeLa cells, or in primary human monocyte-derived macrophages. At a multiplicity of infection of 0.1, zidovudine demonstrated limited anti-EBOV activity in Huh 7 cells. Under certain conditions, lamivudine had low anti-EBOV activity at the maximum concentration tested (320 μM). However, lamivudine never achieved greater than 30% viral inhibition, and the activity was not consistently reproducible. Combination of lamivudine and zidovudine showed no synergistic antiviral activity. Independently, a set of in vitro experiments testing lamivudine and zidovudine for antiviral activity against an Ebola-enhanced green fluorescent protein reporter virus was performed at the Centers for Disease Control and Prevention. No antiviral activity was observed for either compound. A study evaluating the efficacy of lamivudine in a guinea pig model of EVD found no survival benefit. This lack of benefit was observed despite plasma lamivudine concentrations in guinea pig of about 4 μg/ml obtained in a separately conducted pharmacokinetics study. These studies found no evidence to support the therapeutic use of lamivudine for the treatment of EVD.

The global expansion of sports betting has resulted in the formation of (inter)national governing regimes aimed at sustaining revenue and regulating attendant issues, including match-fixing. This article explores the workings of these regimes vis-à-vis the management of match-fixing issues in sport. More particularly, this article focuses on betting monitoring programmes as countermeasures against match-fixing and conceptualises these as social instruments that ultimately define issues and influence the wider integrity agenda of anti-match-fixing campaigns. Analysing documentary, observation and interview data from two disparate monitoring programmes, the results show that betting monitoring is a technical extension of corporate risk management, invariably reflecting the business interests of the betting industry. Therefore, the operating logic of betting monitoring defines match-fixing as an act of sabotaging the competitive edge of betting companies. Moreover, this interest-laden paradigm reigns within the broader policy agenda of sport integrity by equating the betting industry's interest with that of sport. From this, the article suggests that betting monitoring plays a part in the legitimation of commercial gambling by reframing the issue of match-fixing as a common enemy that gambling and sport join forces to combat, not a risk that gambling brings to sport. [ABSTRACT FROM AUTHOR]

Phosphoinositide kinases regulate diverse cellular functions and are important targets for therapeutic development for diseases, such as diabetes and cancer. Preparation of the lipid substrate is crucial for the development of a robust and miniaturizable lipid kinase assay. Enzymatic assays for phosphoinositide kinases often use lipid substrates prepared from lyophilized lipid preparations by sonication, which result in variability in the liposome size from preparation to preparation. Herein, we report a homogeneous 1536-well luciferase-coupled bioluminescence assay for PI5P4Kα. The substrate preparation is novel and allows the rapid production of a DMSO-containing substrate solution without the need for lengthy liposome preparation protocols, thus enabling the scale-up of this traditionally difficult type of assay. The Z'-factor value was greater than 0.7 for the PI5P4Kα assay, indicating its suitability for high-throughput screening applications. Tyrphostin AG-82 had been identified as an inhibitor of PI5P4Kα by assessing the degree of phospho transfer of γ-(32)P-ATP to PI5P; its inhibitory activity against PI5P4Kα was confirmed in the present miniaturized assay. From a pilot screen of a library of bioactive compounds, another tyrphostin, I-OMe tyrphostin AG-538 (I-OMe-AG-538), was identified as an ATP-competitive inhibitor of PI5P4Kα with an IC(50) of 1 µM, affirming the suitability of the assay for inhibitor discovery campaigns. This homogeneous assay may apply to other lipid kinases and should help in the identification of leads for this class of enzymes by enabling high-throughput screening efforts.

The concern for athlete maltreatment in elite sport emerged in response to a wide range of high-profile cases. While diverse theories and concepts have been used to explore the subject, there is a need for non-Western analyses that can attend to the cultures, practices and narratives of Asian states. Drawing on the case of South Korea's elite sport system, this paper scrutinises the mix of institutional practices and narratives that may variously converge to enable maltreatment or diverge, to prompt calls for systemic change. Grounded in ‘new institutionalism’ and a qualitative approach that incorporates document analysis and semi-structured interviews, this research examines maltreatment within a unique Korean Confucian hierarchical socio-cultural context. The results indicate that complementary practices and narratives enable maltreatment and facilitate the continuation of the system. Conversely, this study also investigated instances of divergence highlighting the impetus for change. However, there is some evidence to suggest that accommodating reforms, which remain essentially shaped by existing practices and narratives, often lead to resistance against substantial change. In sum, the combination of convergent and divergent practices and narratives, within the complex and unique cultural and structural context of Korea, signals that while policy changes to address athlete maltreatment are emerging, barriers to fundamental, sustained change remain. [ABSTRACT FROM AUTHOR]

Government sport agencies maintain an enduring interest in National Sport Organisations (NSOs) and deploy a number of tools to make them more effective and efficient. Independent, consultant-led reviews are increasingly used to assess aspects of capability, sustainability, governance, management, and programme delivery. However, it is unknown how NSOs respond to these instruments and the latter's capacity to induce substantive change. This research investigates how and why NSOs respond to independent reviews of their organisations, whether purposefully, passively or politically. Drawing from documents and interviews with NSO officials, findings demonstrate that NSOs respond both purposefully and passively to recommendations advising centralised control over their networks. While there is evidence that responses to reviews invite further state involvement, the mix of responses, along with the finding that 'reviews beget reviews', suggests NSOs maintain considerable agency to 'muddle through' recommendations. This study speaks to why reviews may be repeated and why they may face increasing scepticism. [ABSTRACT FROM AUTHOR]

With growing governmental involvement in sport, there has been a corresponding demand on national sport organizations (NSOs) to operate within performance measurement systems. In this study, we analyze data from New Zealand to determine NSO officials’ perceptions of (a) their reporting relationship with the central agency (Sport and Recreation New Zealand), and (b) the system of performance contracts (or “investment schedules”). Following Norman (2002), we found differing perceptions regarding the legitimacy of performance systems and three tensions emerged. First, the clarity of focus enabled by performance measurement was tempered by the perception of an ever-changing political environment. Second, NSO officials acted strategically and opportunistically at times, marshalling arguments around performance measures to “capture” their principal. Third, neither trust nor distrust in the system necessarily translated into compliance; some NSOs sought independence from the system. This research speaks to the legitimacy of performance systems, a significant but tenuous element to their sustainability. [ABSTRACT FROM AUTHOR]

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Despite growing calls from activists and sport scholars for public consultation over the expenditure of public funds for stadium developments, there remains a lack of empirical research that examines the politics of these practices. This study critically examines the power relations and tensions present in the public-consultation processes and debates over the use of public funds to renovate or rebuild Carisbrook stadium. Specifically, we engage the enabling and constraining institutional mechanisms that structured five public meetings, which emerged as discursive political spaces in the policy-making process. In doing so, we critically examine the discourses that were actively shaped by stadium proponents to fit the mandates of neoliberal growth and resisted by concerned citizens who opposed: (a) the use of public funds to renovate or rebuild the stadium, and (b) a consultation process driven by a public-private partnership of business, civic, and rugby interests that had perplexing consequences for democratic politics in local governance. [ABSTRACT FROM AUTHOR]

This study illustrates how the rules and practices of a task force inquiry shaped the formulation of its policy. Adopting an institutional approach, it analyzes New Zealand's Ministerial Taskforce on Sport, Fitness and Leisure (2001). Specifically, this article investigates the role of institutional arrangements (including public consultation and submission procedures) in shaping, delimiting, and circumscribing that task forces findings and recommendations. The investigation consists of a critical analysis of available texts—including recorded observations of public consultations, written submissions, committee notes—and interviews with task force members. Two features of this task force are described and analyzed: (1) its terms of reference and operative assumptions and (2) its rules and procedures that guided the public participation processes. It is shown that the institutional arrangements can channel debates and thereby recast political relations among interests. [ABSTRACT FROM AUTHOR]

Taskforces, commissions of inquiry, and advisory committees are significant institutional features in the development of government sport policy. This study analyzes New Zealand's Ministerial Taskforce on Sport, Fitness, and Leisure (2001) and uses empirical data gathered from observations of consultations, interviews with committee members, and available documents. It is argued that procedural, organizational, and political considerations significantly shaped and constrained the Taskforce's findings and recommendations. Two fundamental contradictions are discussed. The first concerns the expectations for these bodies to develop both innovative and pragmatic recommendations in light of their ad hoc nature, their broad mandates, and short time lines. The second contradiction speaks to the paradoxical nature of taskforces in developing sport policy, noting in particular their dual roles as both advocates for the sport sector and investigators responsible for addressing problems and issues. [ABSTRACT FROM AUTHOR]

National taskforces and inquiries are used extensively by governments wishing to review their involvement in sport. Underpinning these reviews are dominant ideas like "national unity," or "excellence." Ideas matter in public policy because they form the basis for framing political judgments and because their meanings are continually translated into future plans and actions (Hoppe, 1993. This study investigates the role of ideas in shaping and circumscribing the findings and recommendations emanating from a national taskforce in New Zealand. Information was gathered through interviews with Taskforce members, observations of public consultations, and analysis of submitted documents. Key ideas included notions of efficiency, competitiveness, and leadership. These ideas are discussed, focusing in particular on their contradictory/paradoxical nature and their role in (re)producing power relations. The paper concludes with future research questions and a call for more critical investigations into sport policy-making. [ABSTRACT FROM AUTHOR]

New sport stadia are always contentious projects but in small cities, the stakes may be proportionally higher. This study analyses the turbulence generated by a stadium's approval and financing in Dunedin, New Zealand (2004-2017).It analyses: 1) the city's deferment of advice and fundraising to a charitable trust, 2) the financing apparatus that used council-owned companies (COCs) to obfuscate costs, and 3) the resultant consequences including legal proceedings, COC reforms and company failures. It is suggested that the porousness of governance arrangements invited scrutiny of the links between the city and its COCs, and by extension induced a temporary halt to the softening public-private boundary. [ABSTRACT FROM AUTHOR]

This article deploys the notion of 'self-Orientalization' to empirically investigate the signifying practices across the East–West divide for the construction of global advertising campaigns by Japanese sport brand Asics. In this context, Asics engaged in the practice of self-Orientalization as it formed a creative alliance with Western advertising agencies that represented Japanese culture and identity on behalf of the Japanese-based global headquarters. With insights from interviews with key advertising personnel, the article illuminates practices of negotiation and accommodation between Japanese and European creative workers in shaping 'authentic' and 'cool' signs of Japan. Overall, it suggests that self-Orientalization: (a) entails negotiations over the cultural-economic politics of representation between the Orient and the Occident and (b) simultaneously functions to blur such distinctions at the micro level of social relations and personal identification of creative workers when embodying and performing the Other on behalf of the Self. [ABSTRACT FROM AUTHOR]

Governing state-funded sport is tenuous because of the need to maintain legitimacy and support from political authorisers, stakeholders and network partners/members. The purpose of this paper is to compare/contrast how central sport agencies in Norway and New Zealand create, build or sustain legitimacy through their accountability regimes. More particularly, this comparison distinguishes between input and output sources of legitimacy, where the former is associated with democratic processes (e.g., electoral procedures and public consultation), and the latter is linked with results and demonstrable benefits. While the Norwegian Olympic and Paralympic Committee and Confederation of Sports (NIF) draws legitimacy from its representative membership structures and status as a social movement, Sport New Zealand claims legitimacy on the basis of achieving targets and outputs. In both cases there are emerging pressures to recast input-output legitimating narratives, suggesting their 'depleteability' over time. These shifts are discussed in relation to their influence on policy reforms within environments of accountability that are fluid and incomplete. [ABSTRACT FROM AUTHOR]

Research question: Officiating structures are under increasing pressure to ‘modernise’, raising the need to understand and appraise the suite of reforms aimed at modernising umpire development. The study explores how modernisation has impacted on officiating stakeholders at community and development levels. It investigates how stakeholders have responded to modernisation’s institutional ‘logics’ (e.g. continuous improvement, alignment) and its associated technologies (e.g. accreditations, whole-of-sport planning). Research methods: The study draws from a detailed case analysis of New Zealand’s largest women’s sport organisation: Netball New Zealand (NNZ). Methods include document analysis, semi-structured interviews with national officiating panel members (n = 4) and focus groups with zone representatives (two groups with four participants in each). This study combined inductive and deductive analyses. Results and findings: NNZ emphasised growth and continual improvement by establishing targets and initiating programmes to support more squads and levels of accreditation. It elicited specialist governance structures in umpiring through the addition of regional panels, while pursuing alignment and ‘joined-up’ operations through the advancement of pathways and the integration of athlete development strategies into umpiring. Implications: Modernisation reforms (such as umpire pathways) can lead to increasing volunteer workloads, a greater focus on youth and the emergence of an achievement culture concerned with standards, qualifications and incentives. Modernisation may thus improve youth recruitment, but does not necessarily solve retention problems. This study advances the importance of considering the consequences of modernisation on the capabilities of sport organisations. [ABSTRACT FROM AUTHOR]

The paper re-conceptualizes cultural intermediaries as shapers of “emerging cultural capital” (Prieur, A., and M. Savage. 2013. “Emerging Forms of Cultural Capital.”European Societies15 (2): 246–267; Savage, M., F. Devine, N. Cunningham, M. Taylor, Y. Li, J. Hjellbrekke, and A. Miles. 2013. “A New Model of Social Class? Findings from the BBC’s Great British Class Survey Experiment.”Sociology47 (2): 219–250) and re-frames their practice of signification and negotiation as informed by “multiple dimensions of mediation.” Drawing on a case study of Nike’s transnational advertising production and interviews with key actors within the context of production, the paper examines how the creative/cultural labour process cuts across global and national fields of cultural production and consumption through which popular culture and middle-brow tastes were mediated, signified and represented. In particular, a television campaign for the Japanese youth market was critically analysed to reveal how specific new tastes, lifestyles and consumption practices were legitimized as emerging forms of cultural capital. Consequently, their taste-making practices are profoundly implicated in symbolic struggles and cultural changes emerging within/from the increasingly “globalizing” field of cultural production. [ABSTRACT FROM PUBLISHER]

As match-fixing has emerged as a global problem, states and sports organisations have proposed a range of countermeasures. However, despite their neutral, technocratic appearance, these instruments produce their own political effects. Drawing from a case study of the 2011 South Korean ‘K-League’ football match-fixing scandal that resulted in a raft of countermeasures, this article examines how match-fixing countermeasures (re)organise the power relations within the sports betting industry. Using a qualitative, interpretive multi-method approach, three consequences are suggested. First, the education programme redefines sports ethics by delivering new codes of conduct that are aligned to the demands of betting. Second, regulations instituted by the K-League and the government frame the illegal activity as infringing upon the key stakeholders’ economic interests, further privileging the importance of the betting regime. Third, the sports betting monitoring system itself empowers the sole betting company as a trustworthy ‘fixer’ of the match-fixing problem through co-optation into its policy framework. Consequently, this study shows that key stakeholders manage the risk of losing legitimacy by showcasing their efforts to fight against match-fixing, while also taking advantage of the countermeasures to normalise the business of sports betting, thus furthering their own interests. [ABSTRACT FROM AUTHOR]

To date there has been little explicit theorization concerning the role of risk in global migration studies. Drawing upon Beck's concept of the 'risk society,' this paper presents an investigation of the interplay between societal risk and micro-level migration decision-making. Thick historical contextualization and interview data are used to examine the process of decision-making of South Koreans' migration to New Zealand. Four risk factors were found to contribute to their 'exit' decisions: South Korea's highly competitive, work-oriented society brought about by compressed modernity; North Korea's threat of war and the South's consequent political and military culture; the home nation's obsession with education and academic performance; and the difficulties of reconciling traditional collectivist values with upward mobility. It is argued that while elements of risk may be universal, they need to be understood within specific cultural contexts and in relation to how they influence peoples' lived experiences. [ABSTRACT FROM AUTHOR]

Migration has commonly been theorised as a process that ends with settlement in a new country and thus return visits have not been conceptualised as part of the migration experience. As has been noted in the literature, the return visit is a temporary visit to an individual’s place of birth (or the ‘external homeland’) from a current country of residence which may help immigrants to construct and negotiate a transnational identity between the new and old homes. This study focuses on how one government, South Korea, uses sport as a part of a wider strategy to encourage return visits in order to maintain cultural, economic and political connections with overseas citizens. More specifically, this paper examines the experiences of Korean immigrants living in New Zealand who return to Korea to participate in the annual National Sports Festival. Drawing upon document analysis, interviews and participant observation data, three different types of experiences emerged: (1) athletic experiences through the event itself; (2) nostalgic experiences from reconnecting with families and friends or enjoying forms of culture and entertainment difficult to access in the receiving country; and (3) political and economic experiences through interactions with politicians and business people which may contribute to mutual benefits between their old and new homes. Overall, the paper discusses the experience and implications of Koreans who represent New Zealand in an (inter)national sport and cultural festival and its influence on their transnational lives and identities. [ABSTRACT FROM AUTHOR]

Small states are broadly distinguished on economic, political and cultural grounds and more particularly in relation to their vulnerability and resilience. This paper examines how legitimations around a country’s small size can induce compromises to buttress particular sport policies. Drawing from the New Zealand context, it explores how domestic cooperation can be prompted by the discursive frames of smallness itself. It further suggests that New Zealand’s corresponding ambition to ‘punch above its weight’ has enabled policy transformations to make the sport system appear more legitimate but no less vulnerable. Because scale invites consolidation, targeting and rationing, central sport agencies in small states may have to paradoxically invoke strategies to break the very communal bonds that provide them with the ‘fertile’ conditions for growth and competitive advantage. The study of small states may help scholars and policy-makers to better understand the significance of ‘managed intimacy’ as a counterbalance to neoliberal doctrines. [ABSTRACT FROM PUBLISHER]

An introduction is presented in which the editor discusses several report published within the issue on topics discussed at the 'Sport in Small Nations' International Symposium held at the University of Otago, Dunedin New Zealand in 2015 including importance of sport policies in small states.