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Byline: Sudeshna. Mondal, Samudra. Guha, Abanti. Saha, Loknath. Ghoshal, Debabrata. Bandyopadhyay Background: Psoriasis is a common inflammatory dermatological condition and affects 2-3% population worldwide. Psoriasis area and severity index (PASI) [...]

Byline: Farhat. Fatema, Loknath. Ghoshal, Abanti. Saha, Sristi. Agarwal, Debabrata. Bandyopadhyay Background: Psoriasis is a chronic inflammatory diseaseresulting from a complex interplay of genetic and environmental factors affecting the skin, [...]

Background: Though higher doses of terbinafine are often prescribed to treat dermatophyte infections, it is unknown if such doses are more effective than the conventional dose because comparative data are unavailable. Aim: To compare the efficacy and safety of a once-daily dose of oral terbinafine 250 mg with 500 mg along with topical clotrimazole in the treatment of tinea infections. Methods: A randomised, assessor-blinded, comparative study was carried out. Each group of subjects were administered either 250 mg or 500 mg oral terbinafine once daily for four weeks, along with topical clotrimazole. Clinical improvement was assessed after two weeks and again after four weeks from treatment initiation. Result: A total of 60 patients with tinea corporis and cruris were randomised into two groups receiving either 250 mg (group A) or 500 mg (group B) oral terbinafine, along with clotrimazole cream in both groups. Baseline clinical parameters such as lesional activity (papules, vesicles and pustules), degree of erythema, scaling and severity of itching were comparable between both treatment arms. At the first and second follow-ups, no significant differences were found in the clinical parameters between the two groups. At the end of two weeks 13.8% of group A and 14.3% of group B and after 4 weeks 25.9% of group A and 33.3% of group B participants became KOH negative (P = 1.00 and 0.76, respectively). No significant difference in culture negativity was reported at the end of therapy (four weeks) between the two treatment arms (P = 0.78). Overall cure rates were 20% and 33.3% in the two treatment arms respectively at the end of the study (P = 0.82). Conclusion: Oral terbinafine 250 mg daily yielded a poor cure rate in tinea cruris and corporis after 4 weeks of treatment and an increased dose of 500 mg did not have any additional benefit. [ABSTRACT FROM AUTHOR]

Byline: Adrija. Datta, Somodyuti. Chandra, Abanti. Saha, Amrita. Sil, Nilay. Das Background: Autologous serum therapy aims to supplement the existing pharmacotherapy in chronic urticaria by decreasing the antihistamine pill-burden and [...]

Byline: Indrashis. Podder, Abanti. Saha, Debabrata. Bandyopadhyay Background: At present, the WHO recommends fixed duration multidrug therapy (FD-MDT) for the treatment of leprosy, in which treatment is provided for a [...]

Byline: Satyendranath. Chowdhury, Indrashis. Podder, Abanti. Saha, Debabrata. Bandyopadhyay Background: Contrary to popular perception, several dermatological conditions may be associated with lethal outcome in the absence of timely intervention or [...]

Byline: Indrashis. Podder, Sabari. Bhattacharya, Vivek. Mishra, Tushar. Sarkar, Somodyuti. Chandra, Amrita. Sil, Santasmita. Pal, Dhiraj. Kumar, Abanti. Saha, Koushik. Shome, Debabrata. Bandyopadhyay, Nilay. Das Background: Current therapeutic modalities for [...]

Byline: Satyendra. Chowdhury, Indrasish. Podder, Abanti. Saha, Debabrata. Bandyopadhyay Background: Dermatology is primarily considered to be an outpatient-centered specialty. However, several inpatient admissions to other specialties require dermatologic consultation for [...]

Common wart, also known as verruca vulgaris is characterized by focal proliferation of keratinocytes caused by multiple strains of human papilloma virus (HPV). Conventional treatments like chemical cautery, cryotherapy, electro-cautery, etc often fail to cure verruca satisfactorily. The present work was a randomized, parallel-group, non-inferiority clinical trial with an objective of comparing the effectiveness and safety of subcutaneous MMR versus intralesional MMR vaccine in the treatment of multiple warts. Method: Consenting patients of both sexes of 18-65 years age, who have viral warts and did not receive anti-wart treatment in the last 4 weeks and devoid of any active bacterial or viral skin diseases were included in the study. Interventions: Eligible patients were randomized into either group A (receiving 0.3 ml of intralesional MMR) or group B (receiving 0.5 ml of subcutaneous MMR). A total of three injections were administered at two weeks interval. Outcome Measure: The response was considered complete if there was disappearance of the wart(s) and return of the normal skin markings, partial if the wart(s) was regression in size by 50-99% and no response if there was be 0-49% decrease in wart size. Results: Thirty patients were recruited in each group; 5 of group A and 3 of group B were lost to follow up. Modified intention to treat analysis was performed, so, the last observation of such patients was carried forward and all 60 participants were analysed. Number of warts and size of the largest wart were declined significantly (P < 0.001 and P = 0.001 respectively) in both the treatment arms. No significant difference between two groups were seen. Complete clearance including distant lesions was achieved in 22 patients; 12 (48%) in group A and 10 (37.04%) in group B, but the final outcome at the end of the study showed no significant difference between the two t groups. (P = 0.64). Adverse Events: Only one patient had developed mild fever with tender, enlarged parotid gland after first injection of subcutaneous MMR which resolved within two weeks. Conclusion: Efficacy and safety profile of Subcutaneous and intralesional MMR were almost same. Both can be considered as safe and cost effective treatment of warts while the subcutaneous route may be easier to administer. [ABSTRACT FROM AUTHOR]

Byline: Sibashish. Guha, Debabrata. Bandyopadhyay, Abanti. Saha, Niharika. Lal Porphyria cutanea tarda (PCT), a relatively uncommon metabolic disease, is the most common cutaneous porphyria. Here, we present the case of [...]

Byline: Abanti. Saha, Satyendranath. Chowdhury, Debabrata. Bandyopadhyay Sir, Granular cell tumours (GCTs) are uncommonly encountered and can occur in various organs including the skin. Frequent locations are the tongue (40%), [...]

Byline: Debabrata. Bandyopadhyay, Abanti. Saha Background: Inflammatory linear verrucous epidermal nevus (ILVEN) is a distinct variety of keratinocytic epidermal naevus. In contrast to non-inflammatory epidermal naevi, ILVEN are far less [...]

Byline: Debabrata. Bandyopadhyay, Abanti. Saha Tufted angioma (TA) is a localized benign hamartomatous vascular proliferation usually presenting in the childhood as an erythematous plaque. We report here a rare case [...]

Byline: Vivek. Mishra, Abanti. Saha, Debabrata. Bandyopadhyay, Anirban. Das Verrucous epidermal nevi are congenital, noninflammatory cutaneous hamartomas composed of keratinocytes. They follow the lines of Blaschko and show hyperkeratosis without [...]

Byline: Tirthankar. Gayen, Anupam. Das, Kaushik. Shome, Debabrata. Bandyopadhyay, Dipti. Das, Abanti. Saha Granular cell tumor is a distinctly rare neoplasm of neural sheath origin. It mainly presents as a [...]

Byline: Debabrata. Bandyopadhyay, Abanti. Saha, Sabari. Bhattacharya Cutaneous leiomyomas are benign tumors derived from the smooth muscles of the skin. They are firm, skin-colored to brownish, frequently painful papules and [...]

Byline: Dipti. Das, Anupam. Das, Abanti. Saha, Swapan. Sardar, Kaushik. Shome, Ramesh. Gharami A 16-year-old boy born of non-consanguineous marriage presented with numerous solid elevated lesions over his body. To [...]

Byline: Abanti. Saha, Nilay. Das, Avijit. Hazra, Ramesh. Gharami, Satyendra. Chowdhury, Pijush. Datta Background: Cutaneous adverse drug reactions (CADR) are the most frequent of all manifestations of drug sensitivity and [...]

Byline: Abanti. Saha, Nilay. Das, Ramesh. Gharami, Satyendra. Chowdhury, Pijush. Datta Introduction: Appendageal skin tumors (ATs) are those neoplasms that differentiate toward/arise from pilosebaceous apparatus, apocrine, or eccrine sweat glands. [...]

Background: Dermatology is primarily considered to be an outpatient-centered specialty. However, several inpatient admissions to other specialties require dermatologic consultation for optimum management. Aims: To analyze the causes of inpatient dermatology referrals, departments sending referrals, and impact of dermatology consultation on patient management. Materials and Methods: We conducted a cross-sectional study by analyzing the records of 486 patient referrals over a 4-year period. The demographic details, specialties requesting consultation, cause of referral, and dermatological advice have been recorded and analyzed. Results: Dermatology consultation changed the dermatologic diagnosis and treatment of almost two-thirds of patients. General medicine requested the maximum number of referrals, "skin rash" being the most common cause for referral. Accurate diagnosis on referrals was provided by only 30.2% of nondermatologists. Common dermatological disorders were often misdiagnosed by these physicians, and dermatology referrals had significant impact on the diagnosis and subsequent management of these patients. Conclusion: While dermatologic referral leads to improved patient care, there is a need for better training of nondermatologists enabling them to recognize and treat common dermatoses. [ABSTRACT FROM AUTHOR]

A letter to the editor is presented related to case study of a 30-year old woman suffering with aneurysmal benign fibrous histiocytoma (BFH).

Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nevoid condition characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities, having distinct porokeratotic histopathological features. The lesions usually present at birth or in childhood. We present here a case of late-onset PEODDN in a 23-year-old man who had lesions on the palm, forearm, arm and the chest along the lines of Blaschko, strictly localized to the left side of the body. [ABSTRACT FROM AUTHOR]

Seborrheic keratosis (SK) is a very common benign epidermal proliferation that is prevalent in all races. Most commonly occurring on the trunk, face, scalp, and the extremities, they can occur anywhere on the body except the palms and soles. The most common appearance is that of a very superficial verrucous plaque which appears to be stuck on the surface. Giant lesions are very rare, and their location on the genital area is rarer still. We report here a case of multiple giant SK lesions in a 59-year-old man. [ABSTRACT FROM AUTHOR]

Angiokeratomas are a group of vascular ectasias that involve the papillary dermis and may produce papillomatosis, acanthosis and hyperkeratosis of the epidermis. Angiokeratoma circumscriptum is the least common variant among many types. Angiokeratoma circumscriptum neviforme is a still rarer variety of angiokeratoma, which is classically seen at birth. We report here a case of congenital, linear, unilateral, verrucous plaques on the leg of a young girl, diagnosed as angiokeratoma circumscriptum neviforme (ACN). [ABSTRACT FROM AUTHOR]

A photograph of a 6-year-old girl with a Nevus of Ota is presented.

Competing Interests: There are no conflicts of interest.

Syringocystadenoma papilliferum is a rare benign adnexal tumor commonly located on the head and neck region and is usually associated with a nevus sebaceous. Linear lesions are uncommon and lesions on the breast are extremely rare. We report here a case of linear SCAP occurring de novo on the left breast of a 35-year-old healthy woman. Histopathology showed the characteristic papillary projections lined by double layer of cells inside epidermal invaginations.

Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is an uncommon, benign dermatosis that is characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities with distinct porokeratotic histopathological features. The lesions usually appear at birth or in childhood, although rare cases of late-onset adult PEODDN have been described. Herein we report a case of adult onset PEODDN with unilateral and segmental involvement.