894 results on '"Rubinsztein, David C."'
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2. Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion
3. Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise
4. Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis
5. p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome
6. Apoptotic cell death in disease—Current understanding of the NCCD 2023
7. Mammalian autophagosomes form from finger-like phagophores
8. Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration
9. Vinexin contributes to autophagic decline in brain ageing across species
10. Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
11. PSMC5 insufficiency and P320R mutation impair proteasome function.
12. The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy
13. cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases
14. Breakthroughs and bottlenecks in autophagy research
15. Autophagy in healthy aging and disease
16. VCP/p97 regulates Beclin-1-dependent autophagy initiation
17. International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis.
18. Autophagy regulation by acetylation—implications for neurodegenerative diseases
19. Author Correction: Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury
20. α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation
21. Autophagy in major human diseases
22. TMED9–SEC12, an important “contact” for autophagy
23. Lysosome positioning and mTOR activity in Lowe syndrome
24. Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway–UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies.
25. Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulation
26. Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly
27. Lithium Induces Autophagy by Inhibiting Inositol Monophosphatase
28. Cdk5 Phosphorylation of Huntingtin Reduces Its Cleavage by Caspases: Implications for Mutant Huntingtin Toxicity
29. RIPK1 promotes inflammation and β-amyloid accumulation in Alzheimer’s disease
30. Leucine regulates autophagy via acetylation of the mTORC1 component raptor
31. The autophagy of stress granules.
32. Bacterial and Yeast Chaperones Reduce Both Aggregate Formation and Cell Death in Mammalian Cell Models of Huntington's Disease
33. Markov Chain Monte Carlo Analysis of Human Y-Chromosome Microsatellites Provides Evidence of Biased Mutation
34. Microsatellite and Trinucleotide-Repeat Evolution: Evidence for Mutational Bias and Different Rates of Evolution in Different Lineages
35. Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing
36. Autophagy as a promoter of longevity: insights from model organisms
37. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
38. Genotypes at the GluR6 Kainate Receptor Locus are Associated with Variation in the Age of Onset of Huntington Disease
39. Mammalian phagophores with finger-like shapes emerge from recycling endosomes.
40. Microglial cytokines poison neuronal autophagy via CCR5, a druggable target.
41. LC3-positive structures are prominent in autophagy-deficient cells
42. ULK1‐mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn's mutant
43. Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
44. Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
45. The post‐translational regulation of transcription factor EB (TFEB) in health and disease.
46. Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury
47. An open-label study to assess the feasibility and tolerability of rilmenidine for the treatment of Huntington’s disease
48. Molecular definitions of autophagy and related processes
49. Correction to: Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulation
50. Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
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