Author: "Robert White" / Language: english - Searchworks@Jio Institute Digital Library Search Results

131 results on '"Robert White"'

1. Transcriptionally active chromatin loops contain both ‘active’ and ‘inactive’ histone modifications that exhibit exclusivity at the level of nucleosome clusters

Author: Stefan A. Koestler, Madeleine L. Ball, Leila Muresan, Vineet Dinakaran, and Robert White
Subjects: Chromatin, Histone modification, Epigenetic mark, Transcription, Transcription loop, Nucleosome, Genetics, QH426-470
Abstract: Abstract Chromatin state is thought to impart regulatory function to the underlying DNA sequence. This can be established through histone modifications and chromatin organisation, but exactly how these factors relate to one another to regulate gene expression is unclear. In this study, we have used super-resolution microscopy to image the Y loops of Drosophila melanogaster primary spermatocytes, which are enormous transcriptionally active chromatin fibres, each representing single transcription units that are individually resolvable in the nuclear interior. We previously found that the Y loops consist of regular clusters of nucleosomes, with an estimated median of 54 nucleosomes per cluster with wide variation. In this study, we report that the histone modifications H3K4me3, H3K27me3, and H3K36me3 are also clustered along the Y loops, with H3K4me3 more associated with diffuse chromatin compared to H3K27me3. These histone modifications form domains that can be stretches of Y loop chromatin micrometres long, or can be in short alternating domains. The different histone modifications are associated with different sizes of chromatin clusters and unique morphologies. Strikingly, a single chromatin cluster almost always only contains only one type of the histone modifications that were labelled, suggesting exclusivity, and therefore regulation at the level of individual chromatin clusters. The active mark H3K36me3 is more associated with actively elongating RNA polymerase II than H3K27me3, with polymerase often appearing on what are assumed to be looping regions on the periphery of chromatin clusters. These results provide a foundation for understanding the relationship between chromatin state, chromatin organisation, and transcription regulation – with potential implications for pause-release dynamics, splicing complex organisation and chromatin dynamics during polymerase progression along a gene.
Published: 2024
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2. Attachment-based psychosocial programme for under-privileged school children with adverse life experiences in Istanbul, Turkey

Author: Nasir Warfa, Özden Bademci, Şahin Karasar, and Robert White
Subjects: Attachment Theory, Psychosocial Models, Istanbul School Children, Psychology, BF1-990
Abstract: Abstract Children experiencing educational neglect are likely to experience the harm associated with adverse life experiences and a range of emotional and psychological challenges. Using attachment theory and psychosocial frameworks, we devised and implemented an intervention designed to ameliorate the deleterious effects of challenging behaviours in an elementary school situated in a deprived neighbourhood of Istanbul, Turkey. For a period of eight months, 160 pupils received a psychosocial intervention once a week. Children’s patterns of behaviour, emotions, movements, interactivity, socialisation and interpersonal communications were observed during this period. Core activities of the intervention included library visits, reading, writing and listening games, maths games, drawing, animal animation, leaf making, ball games, parachuting games, colouring, hula-hoop and driver-car role plays. At the end of the intervention, one group of children made significant improvements in behavioural changes while no improvements were observed for another group. Although further research is required to generalize beyond the reference group, the findings suggest that a robust collaboration between inter-agency community partnership and universities can play a crucial role in responding to the needs of marginalized children with psychological and emotional problems.
Published: 2022
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3. The anatomy of transcriptionally active chromatin loops in Drosophila primary spermatocytes using super-resolution microscopy.

Author: Madeleine L Ball, Stefan A Koestler, Leila Muresan, Sohaib Abdul Rehman, Kevin O'Holleran, and Robert White
Subjects: Genetics, QH426-470
Abstract: While the biochemistry of gene transcription has been well studied, our understanding of how this process is organised in 3D within the intact nucleus is less well understood. Here we investigate the structure of actively transcribed chromatin and the architecture of its interaction with active RNA polymerase. For this analysis, we have used super-resolution microscopy to image the Drosophila melanogaster Y loops which represent huge, several megabases long, single transcription units. The Y loops provide a particularly amenable model system for transcriptionally active chromatin. We find that, although these transcribed loops are decondensed they are not organised as extended 10nm fibres, but rather they largely consist of chains of nucleosome clusters. The average width of each cluster is around 50nm. We find that foci of active RNA polymerase are generally located off the main fibre axis on the periphery of the nucleosome clusters. Foci of RNA polymerase and nascent transcripts are distributed around the Y loops rather than being clustered in individual transcription factories. However, as the RNA polymerase foci are considerably less prevalent than the nucleosome clusters, the organisation of this active chromatin into chains of nucleosome clusters is unlikely to be determined by the activity of the polymerases transcribing the Y loops. These results provide a foundation for understanding the topological relationship between chromatin and the process of gene transcription.
Published: 2023
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4. Case report: Immune remission from generalized myasthenia gravis in a dog with a thymoma and cholangiocellular carcinoma

Author: Thomas Mignan, Robert White, Kimberley Stee, Giuseppe Bonanno, Mike Targett, and Mark Lowrie
Subjects: acquired, junctionopathy, acetylcholine, thymectomy, canine, Veterinary medicine, SF600-1100
Abstract: A 9-year-old male neutered Cockapoo was presented with an acute and progressive history of exercise induced weakness involving all limbs, and bilateral decreased ability to blink. Investigations revealed generalized myasthenia gravis alongside the presence of a thymoma and a cholangiocellular carcinoma. Symptomatic treatment through pyridostigmine bromide was used to control clinical signs, and complete surgical removal of the thymoma and cholangiocellular carcinoma was performed. Serum acetylcholine receptor antibody concentration was measured serially. Clinical remission defined as resolution of clinical signs alongside discontinuation of treatment was achieved by day 251 (8.2 months). Immune remission defined as normalization of serum acetylcholine receptor antibody concentration alongside resolution of clinical signs and discontinuation of treatment was achieved by day 566 (18.5 months). Neurological examination was normal, and the owners did not report any clinical deterioration during the final follow-up appointment on day 752 (24 months), hence outcome was considered excellent. This is the first report describing the temporal evolution of serum acetylcholine receptor antibody concentration in a dog with thymoma-associated myasthenia gravis which achieved immune remission following thymectomy. Treatment was successfully discontinued without any evidence of clinical deterioration thereafter despite serum acetylcholine receptor antibody concentration not normalizing for another 315 days (10 months).
Published: 2023
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5. Teachers as educational change agents: what do we currently know? findings from a systematic review [version 1; peer review: 2 approved]

Author: Chris Brown, Anthony Kelly, and Robert White
Subjects: teacher change agents, educational change agents, school change, school system change, self-improving school systems, systematic review, eng, Economic growth, development, planning, HD72-88, Education
Abstract: Change agents are individuals who can successfully transform aspects of how organisations operate. In education, teachers as change agents are increasingly seen as vital to the successful operation of schools and self-improving school systems. To date, however, there has been no systematic investigation of the nature and role of teacher change agents. To address this knowledge gap, we undertook a systematic review into five key areas regarding teachers as change agents. After reviewing 70 outputs we found that current literature predominantly positions teacher change agents as the deliverers of top-down change, with the possibility of bottom-up educational reform currently neglected.
Published: 2021
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6. High-Resolution Quantitative Mapping of Macaque Cervicovaginal Epithelial Thickness: Implications for Mucosal Vaccine Delivery

Author: Kathleen L. Vincent, Patrice A. Frost, Massoud Motamedi, Edward J. Dick, Jingna Wei, Jinping Yang, Robert White, and Marie-Claire Gauduin
Subjects: high-resolution optical coherence tomography imaging, depo medroxyprogesterone, intravaginal, mucosal, rhesus macaque, vaccine delivery, Immunologic diseases. Allergy, RC581-607
Abstract: Vaginal mucosal surfaces naturally offer some protection against sexually transmitted infections (STIs) including Human Immunodeficiency Virus-1, however topical preventative medications or vaccine designed to boost local immune responses can further enhance this protection. We previously developed a novel mucosal vaccine strategy using viral vectors integrated into mouse dermal epithelium to induce virus-specific humoral and cellular immune responses at the site of exposure. Since vaccine integration occurs at the site of cell replication (basal layer 100-400 micrometers below the surface), temporal epithelial thinning during vaccine application, confirmed with high resolution imaging, is desirable. In this study, strategies for vaginal mucosal thinning were evaluated noninvasively using optical coherence tomography (OCT) to map reproductive tract epithelial thickness (ET) in macaques to optimize basal layer access in preparation for future effective intravaginal mucosal vaccination studies. Twelve adolescent female rhesus macaques (5-7kg) were randomly assigned to interventions to induce vaginal mucosal thinning, including cytobrush mechanical abrasion, the chemical surfactant spermicide nonoxynol-9 (N9), the hormonal contraceptive depomedroxyprogesterone acetate (DMPA), or no intervention. Macaques were evaluated at baseline and after interventions using colposcopy, vaginal biopsies, and OCT imaging, which allowed for real-time in vivo visualization and measurement of ET of the mid-vagina, fornices, and cervix. P value ≤0.05 was considered significant. Colposcopy findings included pink, rugated tissue with variable degrees of white-tipped, thickened epithelium. Baseline ET of the fornices was thinner than the cervix and vagina (p
Published: 2021
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7. Chromatin accessibility plays a key role in selective targeting of Hox proteins

Author: Damiano Porcelli, Bettina Fischer, Steven Russell, and Robert White
Subjects: Hox gene, Hox protein, Chromatin, Chromatin accessibility, Hox cofactors, Transcription factor, Biology (General), QH301-705.5, Genetics, QH426-470
Abstract: Abstract Background Hox transcription factors specify segmental diversity along the anterior-posterior body axis in metazoans. While the different Hox family members show clear functional specificity in vivo, they all show similar binding specificity in vitro and a satisfactory understanding of in vivo Hox target selectivity is still lacking. Results Using transient transfection in Kc167 cells, we systematically analyze the binding of all eight Drosophila Hox proteins. We find that Hox proteins show considerable binding selectivity in vivo even in the absence of canonical Hox cofactors Extradenticle and Homothorax. Hox binding selectivity is strongly associated with chromatin accessibility, being highest in less accessible chromatin. Individual Hox proteins exhibit different propensities to bind less accessible chromatin, and high binding selectivity is associated with high-affinity binding regions, leading to a model where Hox proteins derive binding selectivity through affinity-based competition with nucleosomes. Extradenticle/Homothorax cofactors generally facilitate Hox binding, promoting binding to regions in less accessible chromatin but with little effect on the overall selectivity of Hox targeting. These cofactors collaborate with Hox proteins in opening chromatin, in contrast to the pioneer factor, Glial cells missing, which facilitates Hox binding by independently generating accessible chromatin regions. Conclusions These studies indicate that chromatin accessibility plays a key role in Hox selectivity. We propose that relative chromatin accessibility provides a basis for subtle differences in binding specificity and affinity to generate significantly different sets of in vivo genomic targets for different Hox proteins.
Published: 2019
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8. David R. Klein

Author: Eigil Reimers, Olav Hjeljord, Robert White, and Rolf Langvatn
Subjects: Animal culture, SF1-1100
Published: 2020
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9. Supporting Children Experiencing Social and Emotional Needs Who Are Identified by School Staff as at Risk of Exclusion Due to Disruptive Classroom Behavior

Author: Robert White
Abstract: The positive promotion of social and emotional wellbeing in schools can be seen as a means to lessen the impact of social difficulties and behavioral problems on educational engagement. This study employed a multicomponent, whole school approach to promoting positive social and emotional wellbeing. School personnel identified nine primary Key Stage 2 pupils (ages 8 - 10) who were at risk of exclusion due to their disruptive and aggressive behavior. These pupils attended five maintained primary schools located across England. Following analysis of four baseline data points for stability, the Building Schools of Character (BSC) program was commenced. During this period, classroom observations were conducted weekly over the course of one academic school year. All pupils showed a marked decrease in disruptive behavior and were no longer considered at risk of exclusion by staff. These findings suggest a whole school positive social and emotional development approach can decrease disruptive behavior in the classroom.
Published: 2024

10. A decision support tool for assessing cumulative effects on an Arctic migratory tundra caribou population

Author: Don Russell, Anne Gunn, and Robert White
Subjects: arctic national wildlife refuge, caribou, climate, cumulative effects, hydrocarbon, impact assessment, mitigation, modeling, porcupine caribou, Biology (General), QH301-705.5, Ecology, QH540-549.5
Abstract: As large migratory caribou herds decline globally and regional climate trends point to a warmer future, there is a need and a legislative requirement to ensure impacts of industrial development are fully assessed, particularly with respect to cumulative effects. In this paper we use a current proposal, the potential leasing of the 1002 lands on the Alaskan Arctic coastal plain of the Arctic National Wildlife Refuge for hydrocarbon development, to project the potential cumulative effects on the international Porcupine Caribou Herd. Using the caribou cumulative effects model, an existing decision support tool, we evaluate six alternative development scenarios for the 1002 lands, ranging from no leasing to full leasing with standard mitigation conditions. Compared to the no leasing option, at the current population size (218,000 caribou), our analysis projected that the likelihood of a herd decline over a 10-year period would increase from 3% to 19% depending on the leasing scenarios analyzed. This compares to an increased probability of decline from 11% to 26% if the starting population was 100,000, indicative of population estimates in the early 1970s. Our approach accomplishes one of the main steps in a comprehensive cumulative effects assessment, namely the quantification of past, present, and foreseeable future projects on a valued ecosystem component, the Porcupine Caribou Herd. We suggest the testing of underlining assumptions and refinements of the model required to more fully estimate the impacts of development. The use of transparent, quantitative decision support tools in assessing industrial development impacts on Arctic wildlife becomes more critical as climatic changes to Arctic landscapes accelerate.
Published: 2021
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11. 4350 From Translational to Transformational: Establishing CLIC’s Vision for a Research Education and Training Community

Author: Alfred Vitale, Russell Lackey, Melissa Trayhan, and Robert White
Subjects: Medicine
Abstract: OBJECTIVES/GOALS: The new CLIC Education & Career Development Gateway aims to be a translational science workforce ecosystem for CTSAs to share learning and training resources and career opportunities. The Gateway also provides individualized assistance to identify and implement TS learning and training resources. METHODS/STUDY POPULATION: The CLIC Education & Career Development Gateway, located on the CLIC website, is an entry way to: 1) the Education Clearinghouse, a platform where CTSA Program hubs can find and share educational resources individually or as part of resource kits; 2) the Opportunities Board, which includes jobs and mini-sabbaticals from CTSA Program hubs; and 3) the Education & Training Navigator, a personalized approach to education and training requests. These approaches help empower and support a cooperative learning and training community that is inclusive and collaborative, facilitating and amplifying opportunities for the sharing of educational resources throughout the translational science workforce. RESULTS/ANTICIPATED RESULTS: Through a person-centered, direct engagement approach, the anticipated outcomes of these efforts are to promote increased collaboration across CTSA Program Hubs and partners, and the amplification of accessible, relevant existing resources. Another anticipated outcome is increased production of educational materials through the reduction of work duplication and identification of gaps in education and training resources. The Gateway also provides an opportunity to communicate the work and efforts that consortium-level special groups (working groups, special interest groups, etc.) produce. Ongoing evaluations and suggestions will help determine future improvements and functionalities. DISCUSSION/SIGNIFICANCE OF IMPACT: CLIC’s education and training ecosystem promotes education as a community space to facilitate opportunities for collaboration and partnerships, amplifying visibility of the work created by members of the CTSA community, and encouraging a transformative career trajectory for trainees and scholars.
Published: 2020
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12. Real world evidence (RWE) – a disruptive innovation or the quiet evolution of medical evidence generation? [version 2; referees: 2 approved]

Author: Sajan Khosla, Robert White, Jesús Medina, Mario Ouwens, Cathy Emmas, Tim Koder, Gary Male, and Sandra Leonard
Subjects: Medicine, Science
Abstract: Stakeholders in healthcare are increasingly turning to real world evidence (RWE) to inform their decisions, alongside evidence from randomized controlled trials. RWE is generated by analysing data gathered from routine clinical practice, and can be used across the product lifecycle, providing insights into areas including disease epidemiology, treatment effectiveness and safety, and health economic value and impact. Recently, the US Food and Drug Administration and the European Medicines Agency have stated their ambition for greater use of RWE to support applications for new indications, and are now consulting with their stakeholders to formalize standards and expected methods for generating RWE. Pharmaceutical companies are responding to the increasing demands for RWE by developing standards and processes for each stage of the evidence generation pathway. Some conventions are already in place for assuring quality, whereas other processes are specific to the research question and data sources available. As evidence generation increasingly becomes a core role of medical affairs divisions in large pharmaceutical companies, standards of rigour will continue to evolve and improve. Senior pharmaceutical leaders can drive this change by making RWE a core element of their corporate strategy, providing top-level direction on how their respective companies should approach RWE for maximum quality. Here, we describe the current and future areas of RWE application within the pharmaceutical industry, necessary access to data to generate RWE, and the challenges in communicating RWE. Supporting and building on viewpoints from industry and publicly funded research, our perspective is that at each stage of RWE generation, quality will be critical to the impact that RWE has on healthcare decision-makers; not only where RWE is an established and evolving tool, but also in new areas that have the potential to disrupt and to improve drug development pathways.
Published: 2018
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13. Real world evidence (RWE) – a disruptive innovation or the quiet evolution of medical evidence generation? [version 1; referees: 2 approved]

Author: Sajan Khosla, Robert White, Jesús Medina, Mario Ouwens, Cathy Emmas, Tim Koder, Gary Male, and Sandra Leonard
Subjects: Medicine, Science
Abstract: Stakeholders in healthcare are increasingly turning to real world evidence (RWE) to inform their decisions, alongside evidence from randomized controlled trials. RWE is generated by analysing data gathered from routine clinical practice, and can be used across the product lifecycle, providing insights into areas including disease epidemiology, treatment effectiveness and safety, and health economic value and impact. Recently, the US Food and Drug Administration and the European Medicines Agency have stated their ambition for greater use of RWE to support applications for new indications, and are now consulting with their stakeholders to formalize standards and expected methods for generating RWE. Pharmaceutical companies are responding to the increasing demands for RWE by developing standards and processes for each stage of the evidence generation pathway. Some conventions are already in place for assuring quality, whereas other processes are specific to the research question and data sources available. As evidence generation increasingly becomes a core role of medical affairs divisions in large pharmaceutical companies, standards of rigour will continue to evolve and improve. Senior pharmaceutical leaders can drive this change by making RWE a core element of their corporate strategy, providing top-level direction on how their respective companies should approach RWE for maximum quality. Here, we describe the current and future areas of RWE application within the pharmaceutical industry, necessary access to data to generate RWE, and the challenges in communicating RWE. Supporting and building on viewpoints from industry and publicly funded research, our perspective is that at each stage of RWE generation, quality will be critical to the impact that RWE has on healthcare decision-makers; not only where RWE is an established and evolving tool, but also in new areas that have the potential to disrupt and to improve drug development pathways.
Published: 2018
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14. From State Terrorism to Petty Harassment: A Multi-Method Approach to Understanding Repression of Irish Republicans

Author: Robert White
Subjects: Language and Literature
Abstract: Beginning in 1969, the Provisional Irish Republican Army conducted a paramilitary campaign designed to unite Northern Ireland with the Republic of Ireland, creating a 32 county democratic socialist republic. The Provisional IRA’s campaign officially ended in 2005, but former Provisionals and others who followed them continue to pursue armed struggle to this day. The Provisional IRA and its successors are part of the centuries old and highly documented “resistance” of Irish people to British interference in Ireland. Over those centuries, state authorities ‒ the British, Irish, and Northern Irish governments ‒ have “resisted” the dissent of Irish Republicans. This paper draws on three different research methodologies available to social scientists ‒ counts of events that inform quantitative analyses, intensive interviews/oral histories, and visual sociology ‒ and argues that a multi-method approach will provide a better understanding of the dynamics of “resistance” in Ireland and, more generally, social protest.
Published: 2017
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15. Television – The Parallel School

Author: Robert White
Subjects: MEDIA, FAMILY, EDUCATION, MEDIA EDUCATION, Education, Social Sciences, Sociology (General), HM401-1281
Abstract: It is widely recognized that school-aged children in most European countries are watching an average of 2.5 to 3.0 hours of television every day. If we add the time spent with radio, newspapers, internet, magazines, and other leisure-time media, the total amount of time children aged 9-15 spend with media is estimated to be about four to six hours every day. This may be a matter of alarm to some teachers and parents who see students spending less time reading or doing school assignments. They fear that children will not be involved in a balanced set of activities that will develop social skills, commitment to family and Church, and creativity-building hobbies.
Published: 2017

16. Telewizja – druga szkoła

Author: Robert White
Subjects: MEDIA, RODZINA, KSZTAŁCENIE, WYCHOWANIE DO ODBIORU MEDIÓW, Education, Social Sciences, Sociology (General), HM401-1281
Abstract: Powszechnie wiadomo, że dzieci w wieku szkolnym w większości krajów europejskich codziennie oglądają telewizję przez około 2.5 do 3 godzin. Jeśli do tego dodamy czas spędzony na słuchaniu radia, czytaniu gazet i kolorowych magazynów, „błądzeniu” po Internecie i korzystaniu z innych mediów „wolnego czasu”, to całkowity czas poświęcony mediom przez dzieci w wieku 9-15 lat należałoby oszacować na 4-6 godzin dziennie. Dla niektórych nauczycieli i rodziców, którzy zauważają, że uczniowie spędzają mniej czasu na czytaniu i odrabianiu lekcji, może to być wręcz sytuacja alarmowa. Obawiają się oni, że dzieci nie zostaną objęte zajęciami rozwijającymi sprawności społeczne, zaangażowanie w rodzinę i Kościół oraz pobudzające twórczo hobby.
Published: 2017

17. Regions of very low H3K27me3 partition the Drosophila genome into topological domains.

Author: Sherif El-Sharnouby, Bettina Fischer, Jose Paolo Magbanua, Benjamin Umans, Rosalyn Flower, Siew Woh Choo, Steven Russell, and Robert White
Subjects: Medicine, Science
Abstract: It is now well established that eukaryote genomes have a common architectural organization into topologically associated domains (TADs) and evidence is accumulating that this organization plays an important role in gene regulation. However, the mechanisms that partition the genome into TADs and the nature of domain boundaries are still poorly understood. We have investigated boundary regions in the Drosophila genome and find that they can be identified as domains of very low H3K27me3. The genome-wide H3K27me3 profile partitions into two states; very low H3K27me3 identifies Depleted (D) domains that contain housekeeping genes and their regulators such as the histone acetyltransferase-containing NSL complex, whereas domains containing moderate-to-high levels of H3K27me3 (Enriched or E domains) are associated with regulated genes, irrespective of whether they are active or inactive. The D domains correlate with the boundaries of TADs and are enriched in a subset of architectural proteins, particularly Chromator, BEAF-32, and Z4/Putzig. However, rather than being clustered at the borders of these domains, these proteins bind throughout the H3K27me3-depleted regions and are much more strongly associated with the transcription start sites of housekeeping genes than with the H3K27me3 domain boundaries. While we have not demonstrated causality, we suggest that the D domain chromatin state, characterised by very low or absent H3K27me3 and established by housekeeping gene regulators, acts to separate topological domains thereby setting up the domain architecture of the genome.
Published: 2017
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18. Autodidactic sonnets

Author: Robert White
Subjects: shakespeare, sonnets, sidney, spenser, keats, pedagogy, Fine Arts, Arts in general, NX1-820, General Works, History of scholarship and learning. The humanities, AZ20-999
Abstract: True to one of the themes in this issue of our journal, my essay raises two broadly pedagogical questions. First, what did Shakespeare learn about writing sonnets from his most accomplished contemporaries, Sidney and Spenser, and secondly what does he teach his own readers about how to read his sonnets? A single answer to both is proposed: he learned and taught that the abiding and primary subject of the sonnet is the sonnet itself and the kind of beauty it offers to readers. For want of a better term, “autodidactic” is proffered as a clumsy word to describe this two-way process of self-learning and self-teaching.
Published: 2016
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19. Techno-Economic and Life Cycle Impacts Analysis of Direct Methanation of Glycerol to Bio-Synthetic Natural Gas at a Biodiesel Refinery

Author: Robert White, Freddy Segundo Navarro-Pineda, Timothy Cockerill, Valerie Dupont, and Julio César Sacramento Rivero
Subjects: bio-SNG, glycerol, soybean biodiesel, natural gas, life cycle impacts analysis, techno-economic analysis, Technology
Abstract: An economic and environmental feasibility study were carried out on the thermochemical conversion of glycerol to medium methane content biological synthetic natural gas (bio-SNG). A plant that processed 497 kg·h−1 of glycerol to bio-SNG was modelled as an on-site addition to a soybean biodiesel plant based in Missouri (USA) that produced 30 million litres of soybean biodiesel per year. Assuming the glycerol contained only 80 wt% free glycerol, the bio-SNG could substitute up to 24% of the natural gas at the soybean biodiesel plant. The discounted cash flow analysis showed it was possible to generate positive NPVs and achieve internal rates of return within the hurdle rate (12%) for biomass gasification technologies. From the environmental analysis it was found that the bio-SNG could reduce global warming potential by 28% when compared to conventional natural gas in the USA and translates to roughly 7% reduction in biodiesel natural gas emissions, if the maximum 24% of natural gas were to be substituted by bio-SNG. The work highlights the potential to divert waste glycerol to an onsite energy vector at soybean biodiesel plants with minimal change to the main biodiesel production process and potential reductions to soybean biodiesel global warming potential.
Published: 2019
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20. A One-Year Economic Evaluation of Six Alternative Strategies for the Management of Uninvestigated Upper Gastrointestinal Symptoms in Canadian Primary Care

Author: Alan N Barkun, Ralph Crott, Carlo A Fallone, Wendy A Kennedy, Jean Lachaine, Carey Levinton, David Armstrong, Naoki Chiba, Alan Thomson, Sander Veldhuyzen van Zanten, Paul Sinclair, Sergio Escobedo, Bijan Chakraborty, Sandra Smyth, Robert White, Helen Kalra, and Krista Nevin
Subjects: Diseases of the digestive system. Gastroenterology, RC799-869
Abstract: BACKGROUND: The cost-effectiveness of initial strategies in managing Canadian patients with uninvestigated upper gastrointestinal symptoms remains controversial.
Published: 2010
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21. Primate-to-Human Retroviral Transmission in Asia

Author: Lisa Jones-Engel, Gregory A. Engel, Michael A. Schillaci, Aida Rompis, Artha Putra, Komang Gde Suaryana, Agustin Fuentes, Brigitte Beer, Sarah Hicks, Robert White, Brenda Wilson, and Jonathan S. Allan
Subjects: Disease Transmission, Simian foamy virus, exogenous retrovirus, primate zoonoses, Macaca, Southeast Asia, Medicine, Infectious and parasitic diseases, RC109-216
Abstract: We describe the first reported transmission to a human of simian foamy virus (SFV) from a free-ranging population of nonhuman primates in Asia. The transmission of an exogenous retrovirus, SFV, from macaques (Macaca fascicularis) to a human at a monkey temple in Bali, Indonesia, was investigated with molecular and serologic techniques. Antibodies to SFV were detected by Western blotting of serum from 1 of 82 humans tested. SFV DNA was detected by nested polymerase chain reaction (PCR) from the blood of the same person. Cloning and sequencing of PCR products confirmed the virus's close phylogenetic relationship to SFV isolated from macaques at the same temple. This study raises concerns that persons who work at or live around monkey temples are at risk for infection with SFV.
Published: 2005
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22. Engineering of macaque CD4+ T cells and CD34+ hematopoietic stem cells resistant to in vitro SIV infection using zinc finger nucleases

Author: Peter Lentz, Gregory Bonello, Fuchun Zhou, Mary Salas, Magdalena Cepeda, Robert White, and Marie-Claire Gauduin
Subjects: Microbiology, QR1-502, Public aspects of medicine, RA1-1270
Published: 2016
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23. Characterisation of Drosophila UbxCPTI000601 and hthCPTI000378 Protein Trap Lines

Author: Siew Woh Choo, Ching Yew Beh, Steven Russell, and Robert White
Subjects: Technology, Medicine, Science
Abstract: In Drosophila, protein trap strategies provide powerful approaches for the generation of tagged proteins expressed under endogenous control. Here, we describe expression and functional analysis to evaluate new Ubx and hth protein trap lines generated by the Cambridge Protein Trap project. Both protein traps exhibit spatial and temporal expression patterns consistent with the reported endogenous pattern in the embryo. In imaginal discs, Ubx-YFP is expressed throughout the haltere and 3rd leg imaginal discs, while Hth-YFP is expressed in the proximal regions of haltere and wing discs but not in the pouch region. The UbxCPTI000601 line is semilethal as a homozygote. No T3/A1 to T2 transformations were observed in the embryonic cuticle or the developing midgut. The homozygous survivors, however, exhibit a weak haltere phenotype with a few wing-like marginal bristles on the haltere capitellum. Although hthCPTI000378 is completely lethal as a homozygote, the hthCPTI000378/hthC1 genotype is viable. Using a hth deletion (Df(3R)BSC479) we show that hthCPTI000378/Df(3R)BSC479 adults are phenotypically normal. No transformations were observed in hthCPTI000378, hthCPTI000378/hthC1, or hthCPTI000378/Df(3R)BSC479 embryonic cuticles. We have successfully characterised the Ubx-YFP and Hth-YFP protein trap lines demonstrating that the tagged proteins show appropriate expression patterns and produce at least partially functional proteins.
Published: 2014
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24. Genome-wide analysis of the binding of the Hox protein Ultrabithorax and the Hox cofactor Homothorax in Drosophila.

Author: Siew Woh Choo, Robert White, and Steven Russell
Subjects: Medicine, Science
Abstract: Hox genes encode a family of transcription factors that are key developmental regulators with a highly conserved role in specifying segmental diversity along the metazoan body axis. Although they have been shown to regulate a wide variety of downstream processes, direct transcriptional targets have been difficult to identify and this has been a major obstacle to our understanding of Hox gene function. We report the identification of genome-wide binding sites for the Hox protein Ultrabithorax (Ubx) using a YFP-tagged Drosophila protein-trap line together with chromatin immunoprecipitation and microarray analysis. We identify 1,147 genes bound by Ubx at high confidence in chromatin from the haltere imaginal disc, a prominent site of Ubx function where it specifies haltere versus wing development. The functional relevance of these genes is supported by their overlap with genes differentially expressed between wing and haltere imaginal discs. The Ubx-bound gene set is highly enriched in genes involved in developmental processes and contains both high-level regulators as well as genes involved in more basic cellular functions. Several signalling pathways are highly enriched in the Ubx target gene set and our analysis supports the view that Hox genes regulate many levels of developmental pathways and have targets distributed throughout the gene network. We also performed genome-wide analysis of the binding sites for the Hox cofactor Homothorax (Hth), revealing a striking similarity with the Ubx binding profile. We suggest that these binding profiles may be strongly influenced by chromatin accessibility and provide evidence of a link between Ubx/Hth binding and chromatin state at genes regulated by Polycomb silencing. Overall, we define a set of direct Ubx targets in the haltere imaginal disc and suggest that chromatin accessibility has important implications for Hox target selection and for transcription factor binding in general.
Published: 2011
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25. Stability and dynamics of polycomb target sites in Drosophila development.

Author: Camilla Kwong, Boris Adryan, Ian Bell, Lisa Meadows, Steven Russell, J Robert Manak, and Robert White
Subjects: Genetics, QH426-470
Abstract: Polycomb-group (PcG) and Trithorax-group proteins together form a maintenance machinery that is responsible for stable heritable states of gene activity. While the best-studied target genes are the Hox genes of the Antennapedia and Bithorax complexes, a large number of key developmental genes are also Polycomb (Pc) targets, indicating a widespread role for this maintenance machinery in cell fate determination. We have studied the linkage between the binding of PcG proteins and the developmental regulation of gene expression using whole-genome mapping to identify sites bound by the PcG proteins, Pc and Pleiohomeotic (Pho), in the Drosophila embryo and in a more restricted tissue, the imaginal discs of the third thoracic segment. Our data provide support for the idea that Pho is a general component of the maintenance machinery, since the majority of Pc targets are also associated with Pho binding. We find, in general, considerable developmental stability of Pc and Pho binding at target genes and observe that Pc/Pho binding can be associated with both expressed and inactive genes. In particular, at the Hox complexes, both active and inactive genes have significant Pc and Pho binding. However, in comparison to inactive genes, the active Hox genes show reduced and altered binding profiles. During development, Pc target genes are not simply constantly associated with Pc/Pho binding, and we identify sets of genes with clear differential binding between embryo and imaginal disc. Using existing datasets, we show that for specific fate-determining genes of the haemocyte lineage, the active state is characterised by lack of Pc binding. Overall, our analysis suggests a dynamic relationship between Pc/Pho binding and gene transcription. Pc/Pho binding does not preclude transcription, but levels of Pc/Pho binding change during development, and loss of Pc/Pho binding can be associated with both stable gene activity and inactivity.
Published: 2008
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26. CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex.

Author: Eimear E Holohan, Camilla Kwong, Boris Adryan, Marek Bartkuhn, Martin Herold, Rainer Renkawitz, Steven Russell, and Robert White
Subjects: Genetics, QH426-470
Abstract: Insulator or enhancer-blocking elements are proposed to play an important role in the regulation of transcription by preventing inappropriate enhancer/promoter interaction. The zinc-finger protein CTCF is well studied in vertebrates as an enhancer blocking factor, but Drosophila CTCF has only been characterised recently. To date only one endogenous binding location for CTCF has been identified in the Drosophila genome, the Fab-8 insulator in the Abdominal-B locus in the Bithorax complex (BX-C). We carried out chromatin immunopurification coupled with genomic microarray analysis to identify CTCF binding sites within representative regions of the Drosophila genome, including the 3-Mb Adh region, the BX-C, and the Antennapedia complex. Location of in vivo CTCF binding within these regions enabled us to construct a robust CTCF binding-site consensus sequence. CTCF binding sites identified in the BX-C map precisely to the known insulator elements Mcp, Fab-6, and Fab-8. Other CTCF binding sites correlate with boundaries of regulatory domains allowing us to locate three additional presumptive insulator elements; "Fab-2," "Fab-3," and "Fab-4." With the exception of Fab-7, our data indicate that CTCF is directly associated with all known or predicted insulators in the BX-C, suggesting that the functioning of these insulators involves a common CTCF-dependent mechanism. Comparison of the locations of the CTCF sites with characterised Polycomb target sites and histone modification provides support for the domain model of BX-C regulation.
Published: 2007
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27. Towards a protocol for community monitoring of caribou body condition

Author: Gary Kofinas, Phil Lyver, Don Russell, Robert White, Augie Nelson, and Nicholas Flanders
Subjects: caribou management, caribou, monitoring body condition, local knowledge, traditional ecological knowledge (TEK), Animal culture, SF1-1100
Abstract: Effective ecological monitoring is central to the sustainability of subsistence resources of indigenous communities. For caribou, Arctic indigenous people's most important terrestrial subsistence resource, body condition is a useful measure because it integrates many ecological factors that influence caribou productivity and is recognized by biologists and hunters as meaningful. We draw on experience working with indigenous communities to develop a body condition monitoring protocol for harvested animals. Local indigenous knowledge provides a broad set of caribou health indicators and explanations of how environmental conditions may affect body condition. Scientific research on caribou body condition provides a basis to develop a simple dichotomous key that includes back fat, intestinal fat, kidney fat and marrow¬fat, as measures of body fat, which in autumn to early winter correlates with the likelihood of pregnancy. The dichotomous key was formulated on "expert knowledge" and validated against field estimates of body composition. We compare local indigenous knowledge indicators with hunter documented data based on the dichotomous key. The potential con¬tribution of community body condition monitoring can be realized through the continued comparative analysis of datasets. Better communication among hunters and scientists, and refinement of data collection and analysis methods are recommended. Results suggest that specific local knowledge may become generalized and integrated between regions if the dichotomous key is used as a generalized (semi-quantitative) index and complemented with other science and community-based assessments.
Published: 2003
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28. Educational Leadership and Critical Theory: What Can School Leaders Learn from the Critical Theorists

Author: Charles L. Lowery, Chetanath Gautam, Robert White, Michael E. Hess and Charles L. Lowery, Chetanath Gautam, Robert White, Michael E. Hess
Published: 2023

29. The New Fortune Theatre: That Vast Open Stage

Author: Ciara Rawnsley & Robert White and Ciara Rawnsley & Robert White
Published: 2018

30. Heterodyne Method of Sulphide Detection. Latest field results

Author: Robert White, Steve Collins, Keith Leslie, and Andrew Sloot
Subjects: Heterodyne, mixability, non-linear, sulphide, Kempfield
Abstract: The Heterodyne Method uses the semiconducting properties of sulphide minerals to produce secondary signals that may be used to map occurrences of those minerals and possibly distinguish between different types of sulphides and graphite. Several field trials of this technique have been run over the Kempfield prospect in eastern NSW. Many of these trials were plagued by logistic and technical difficulties but a considerable amount of valuable data and experience has been obtained. The results indicate show that this technique produces mappable results. However, the response to sulphide minerals has only been sporadic and it is clear that the secondary signals produced by this method are extremely complex. Further work is needed to resolve technical issues and ascertain the geological relevance of the large amount of information contained in the heterodyne signals., Open-Access Online Publication: May 22, 2023
Published: 2023
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31. Out of the Ashes: An Oral History of the Provisional Irish Republican Movement

Author: Robert White and Robert White
Published: 2017

32. Music of the Minnesinger and Early Meistersinger : A Bibliography

Author: LINKER, ROBERT WHITE and LINKER, ROBERT WHITE
Published: 2020
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33. The Relationship between Academic Integration and Student Success in Distance Learning in the Kentucky Community and Technical College System

Author: Johnson, Robert White
Abstract: This dissertation is a study of factors that contribute to dropout from distance learning classes in the Kentucky Community and Technical College System (KCTCS). It is divided into five chapters. Chapter One gives a history of distance learning through in KCTCS. It includes the background of the study, statement of the problem, purpose of the study, the research questions, major concepts, and the significance of the study. The chapter concludes with a definition of terms and limitations. Chapter Two is a literature review of factors associated with student success in distance learning courses in the community college. It examines the theoretical framework for student dropout from distance learning suggested by Kember (1989). Chapter Three describes the methodology used to address and answer the research questions of this study. The dichotomous dependent variable was completion. The seven independent variables were gender, ethnicity, age, financial aid status, earliest logic (eagerness), number of logins (dedication) and number of course mail messages sent by student (participation) The data were collected from the KCTCS student information system and from the ANGEL course management system. Subjects for this study were community college student enrolled statewide in online versions of ENG 101 and ENG 102 during the 2004-2005 academic year (N = 405). Chapter Four provides the results of the study. The primary statistical analysis methods used to determine the relative impact of each independent variable on the dependent variable of success were discriminate function analysis and multiple regression. Of the variables tested, dedication and financial aid status were statistically significant predictors of success. Descriptive statistics suggested that African-American and female students were more likely to form social relationships and succeed more often as a result of academic integration. Chapter Five contains a summary of the study, implications, and suggestions for further research. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]
Published: 2009

34. Who is to Blame?: Disasters, nature, and acts of God

Author: Robert White FRS and Robert White FRS
Published: 2014

35. Biofuel Blending Reduces Aircraft Engine Particle Emissions at Cruise Conditions

Author: Richard H Moore, Kenneth L Thornhill, Bernadett Weinzierl, Daniel Sauer, Eugenio D'Ascoli, Brian Beaton, Andreas J Beyersdorf, Dan Bulzan, Chelsea Corr, Ewan Crosbie, Robert Martin, Dean Riddick, Michael Shook, Gregory Slover, Christiane Voigt, Robert White, Edward Winstead, Richard Yasky, Luke D Ziemba, Anthony Brown, Hans Schlager, and Bruce E Anderson
Subjects: Aircraft Propulsion And Power
Abstract: Aviation aerosol emissions have a disproportionately large climatic impact because they are emitted high in the relatively pristine upper troposphere where they can form linear contrails and influence cirrus clouds. Research aircraft from NASA, DLR, and NRC Canada made airborne measurements of gaseous and aerosol composition and contrail microphysical properties behind the NASA DC-8 aircraft at cruise altitudes. The DC-8 CFM-56-2C engines burned traditional medium-sulfur Jet A fuel as well as a low-sulfur Jet A fuel and a 50:50 biofuel blend. Substantial, two-to-three-fold emissions reductions are found for both particle number and mass emissions across the range of cruise thrust operating conditions. These observations provide direct and compelling evidence for the beneficial impacts of biojet fuel blending under real-world conditions.
Published: 2017
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36. Research data infrastructure for high-throughput experimental materials science

Author: Dave Evenson, Marcus Schwarting, Caleb Phillips, John D. Perkins, Robert White, Kevin R. Talley, Nick Wunder, William Tumas, Kristin Munch, Andriy Zakutayev, and Matthew Eash
Subjects: Condensed Matter - Materials Science, Process (engineering), experimental, workflow, metadata, General Decision Sciences, Experimental data, Materials Science (cond-mat.mtrl-sci), FOS: Physical sciences, Descriptor, Asset (computer security), Pipeline (software), Data science, Domain (software engineering), materials, Set (abstract data type), Metadata, Workflow, data, Data analysis, high-throughput
Abstract: Summary The High-Throughput Experimental Materials Database (HTEM-DB, htem.nrel.gov) is a repository of inorganic thin-film materials data collected during combinatorial experiments at the National Renewable Energy Laboratory (NREL). This data asset is enabled by NREL's Research Data Infrastructure (RDI), a set of custom data tools that collect, process, and store experimental data and metadata. Here, we describe the experimental data flow from the RDI to the HTEM-DB to illustrate the strategies and best practices currently used for materials data at NREL. Integration of the data tools with experimental instruments establishes a data communication pipeline between experimental researchers and data scientists. This work motivates the creation of similar workflows at other institutions to aggregate valuable data and increase their usefulness for future machine learning studies. In turn, such data-driven studies can greatly accelerate the pace of discovery and design in the materials science domain., Graphical abstract, Highlights • Automated curation of experimental materials data • Integration of data tools into the experimental laboratory • Simple, effective, and flexible data archival system • Collection of metadata for enhanced total data value, The bigger picture For machine learning to make significant contributions to a scientific domain, algorithms must ingest and learn from high-quality, large-volume datasets. The Research Data Infrastructure (RDI) that feeds the High-Throughput Experimental Materials Database (HTEM-DB, htem.nrel.gov) provides such a dataset from existing experimental data streams at the National Renewable Energy Laboratory (NREL). The described methods for curating experimental data can be applied to other materials research laboratory settings, paving the way for increased application of machine learning to materials science. In turn, the resulting new materials and new knowledge will benefit the society by advancing new technologies in energy, fuels, computing, security, and other important areas., This article describes the Research Data Infrastructure (RDI) and its application to create the High-Throughput Experimental Materials Database (HTEM-DB, htem.nrel.gov) at the National Renewable Energy Laboratory (NREL). RDI is a set of custom data tools that collect, process, and store experimental data and metadata, enabling the HTEM-DB repository for inorganic thin-film materials data collected during combinatorial experiments. This coupled experimental and data workflow from the RDI to the HTEM-DB illustrates the best practices currently used for materials data at NREL.
Published: 2021

37. Teachers as educational change agents: what do we currently know?: Findings from a systematic review

Author: Chris Brown, Anthony Kelly, and Robert White
Subjects: Successful operation, business.industry, Key (cryptography), School change, Public relations, Psychology, business
Abstract: Change agents are individuals who can successfully transform aspects of how organisations operate. In education, teachers as change agents are increasingly seen as vital to the successful operation of schools and self-improving school systems. To date, however, there has been no systematic investigation of the nature and role of teacher change agents. To address this knowledge gap, we undertook a systematic review into five key areas regarding teachers as change agents. After reviewing 70 outputs we found that current literature predominantly positions teacher change agents as the deliverers of top-down change, with the possibility of bottom-up educational reform currently neglected.
Published: 2021

38. Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at $ \sqrt{s} $ = 13 TeV

Author: I. A. Melzer-Pellmann, Brian L Winer, Mikhail Danilov, Francesca Nessi-Tedaldi, C. Adloff, Andreas Werner Jung, Mehmet Özgür Sahin, Donato Creanza, Chandiprasad Kar, Marc Dobson, Umberto Dosselli, M. Gola, Pieter David, Olga Evdokimov, Junghwan Goh, A. García Alonso, Livio Fanò, K. J. Pena Rodriguez, T. Boccali, Maurizio Pierini, David Cussans, Bisnupriya Sahu, Anadi Canepa, E. A. De Wolf, Benjamin Charles Radburn-Smith, K. Hurtado Anampa, A. Baden, Z. Y. You, M. Barrio Luna, Cilicia Uzziel Perez, Sabino Meola, Roberto Covarelli, Sebastian Brommer, Hideki Okawa, Laurits Tani, Liam Wezenbeek, Yuta Takahashi, Sergio Cittolin, Virgil E Barnes, Irakli Lomidze, Andrzej Novak, Efe Yigitbasi, A Dodonova, S. Fonseca De Souza, Graham Wilson, Zviad Tsamalaidze, Alessio Ghezzi, A. Bornheim, Dario Menasce, Abideh Jafari, Sebastian Wieland, C. Oropeza Barrera, Sioni Summers, Sumit Keshri, Simone Pigazzini, Grigory Pivovarov, S. Slabospitskii, Gianny Mestdach, E. Eskut, R. F. Von Cube, Claire Savard, P. Martinez Ruiz del Arbol, Sandra S. Padula, Yiwen Wen, Paolo Vitulo, William J Spalding, Grace Haza, Johannes Haller, Kinga Anna Wozniak, Kai Wei, S. Choi, L. Marchese, Dan Quach, Nancy Marinelli, Guillaume Bourgatte, Caroline Collard, Stefano Bianco, Brandon Chiarito, Vadim Oreshkin, Byung Hun Oh, Francesca Cavallari, D. Soldi, Brendan Regnery, Mikko Lotti, Natasa Raicevic, Georgios Anagnostou, Melody A. Swartz, Maxwell Chertok, Danek Kotlinski, A. Melo, Catherine Schiber, Yury Ivanov, Stephen Sanders, Andre Sznajder, Serdal Damarseckin, Gianni Zumerle, M. J. Kim, Paolo Dini, Fabio Ravera, Maren Tabea Meinhard, Simranjit Singh Chhibra, A. Escalante Del Valle, J. F. de Trocóniz, Ugur Kiminsu, G. P. Van Onsem, Sunil Bansal, S. Sánchez Navas, Mauro Emanuele Dinardo, Sven Dildick, Nhan Viet Tran, Mohammad Abrar Wadud, Christof Roland, Yao Yao, David Colling, Yuri Gershtein, Emmanuelle Perez, G. G. Da Silveira, Cristina Riccardi, Rogelio Reyes-Almanza, Jose Chinellato, Richard Cavanaugh, Ali Eren Simsek, David Barney, Aleksandra Lelek, Stephanie Beauceron, Maryam Bayatmakou, Plamen Iaydjiev, Michael Lukasik, Evan Ranken, J. Park, S. Wunsch, Martti Raidal, Nicholas Smith, Arnab Laha, Amina Zghiche, Emily MacDonald, Danilo Meuser, Andrew Gilbert, Ridhi Chawla, Nikola Godinovic, Hualin Mei, Altan Cakir, Paolo Meridiani, Aron Soha, Ulrich Husemann, A. Manousakis-Katsikakis, Fabio Monti, Khawla Jaffel, Jean-Charles Fontaine, A. De Cosa, Caleb Fangmeier, S. Cerci, Vinicius Massami Mikuni, S. B. Oh, Alexander Malakhov, Günter Flügge, Francesco Fallavollita, Simon Fayer, Danyyl Brzhechko, M. Naimuddin, Burin Asavapibhop, Xunwu Zuo, Anton Dimitrov, Luciano Di Fiore, Jinsook Kim, Marco Rovere, Robert Clare, I. Kravchenko, Karl Gill, James Bueghly, Matthew Nguyen, V. Rodríguez Bouza, E. Gurpinar Guler, Pedro G Mercadante, Hans-Christian Kaestli, Anup Kumar Sikdar, Gerry Bauer, A.N. Kozyrev, Werner Lustermann, Andromachi Tsirou, A. Di Pilato, James Strait, Robert Hirosky, Shawn Zaleski, Meenakshi Narain, J. León Holgado, Cristina Fernandez Bedoya, Isabel Pedraza, Paolo Azzurri, Emilien Chapon, M. R. Di Domenico, Vittorio Raoul Tavolaro, I. O. Atakisi, Simone Scarfi, H. El Faham, Maryam Zeinali, Kevin Nash, Thea Klaeboe Aarrestad, Gourab Saha, Valentina Dutta, Marco Toliman Lucchini, Mauricio Thiel, Ilya Gorbunov, Peter Timothy Cox, Torben Lange, Lucas Torterotot, Patrizia Azzi, A. Kasem, Thomas Hebbeker, Paul Lecoq, Hyejin Kwon, Jeremy Mans, Wesley Terrill, S. H. Lee, Gage Dezoort, C. Ramón Álvarez, D. E. Pellett, Konstantinos Theofilatos, Sandor Czellar, Elizabeth Starling, Nan Lu, René Caspart, N. Chernyavskaya, Elisabetta Manca, Nicolò Trevisani, P. Kontaxakis, Manuel Giffels, Alex Dorsett, Christoph Grab, Chun Cheng, Martin Delcourt, Henning Kirschenmann, S. Bhattacharya, Ia Iashvili, Roberto Seidita, Jean-Roch Vlimant, Brajesh C Choudhary, Andrea Trapote, Sébastien Viret, Y. Xiang, Guo-Ming Chen, Mohammad Hassan Hassanshahi, Arabella Martelli, Muhammad Ahmad, N. Bin Norjoharuddeen, Suman Bala Beri, Helena Bialkowska, Nur Zulaiha Jomhari, Vivian O'Dell, Charlotte Cooke, Julie Managan Hogan, Panos A Razis, Samuel Baxter, Ernesto Migliore, Hans-Jürgen Simonis, A. Vartak, Tyler Lam, Nadja Strobbe, Jean-Laurent Agram, Gabriella Pugliese, Todd Adams, Andrew Wightman, Biagio Rossi, Wit Busza, Kevin Lannon, G. Della Ricca, Alexis Pompili, Abraham Tishelman-Charny, Ang Li, Y. D. Kim, Stephen Wimpenny, Henning Flacher, J. Wanczyk, Nikolaos Manthos, Lorenzo Vigilante, Martin Grunewald, J. Piedra Gomez, Peter Robmann, Anterpreet Kaur, Mehmet Kaya, S. Ha, Intae Yu, A. Abreu, A. De Roeck, A. J. Campbell, L. V. Kardapoltsev, Amitabh Lath, G. L. Pinna Angioni, Angela Mehta, Miranda Bryson, Pierluigi Paolucci, M Myllymäki, Candan Isik, Zukhaimira Zolkapli, Michael Mulhearn, Jie Xiao, Jeroen Hegeman, A. David, Ksenia Shchelina, Steffie Ann Thayil, K. Vellidis, E. Di Marco, Gaël Touquet, Jeremi Niedziela, Oleg Prokofyev, Wolfram Erdmann, Radia Redjimi, Ivan Ovtin, C. Martinez Rivero, Chiara Amendola, A. Di Florio, Giorgio Apollinari, M. A. Shah, F. Pandolfi, Kyeongpil Lee, Fabio Iemmi, Rishi Patel, Y. D. Oh, Fabrizio Palla, Samila Muthumuni, S. Afanasiev, A. Álvarez Fernández, R. Kumar Verma, Patrick Connor, Anna Elliott-Peisert, Vuko Brigljevic, Lucia Silvestris, David Taylor, B. Jayatilaka, Josry Metwally, Aran Garcia-Bellido, Vyacheslav Valuev, Ren-Yuan Zhu, Alp Akpinar, Rajat Gupta, Serguei Ganjour, Debabrata Bhowmik, A. Carvalho Antunes De Oliveira, A. Meyer, Reyer Band, Younes Otarid, Guenakh Mitselmakher, S. Orfanelli, K Christoforou, Jordan Damgov, Pierluigi Bortignon, Guido Tonelli, Yasser Maghrbi, Zeljko Antunovic, Mykyta Shchedrolosiev, Debarati Roy, Furkan Dolek, Franco Ligabue, E. M. Da Costa, Giovanni Abbiendi, E. Bossini, Zuhal Seyma Demiroglu, Felipe Ramirez, Berkan Kaynak, Marc Osherson, Steven F. Maier, Francesco Setti, Brent Yates, Emanuela Barberis, Avraham Yagil, I. Dremin, Michael Dittmar, Aristotelis Kyriakis, Joona Havukainen, J. A. Brochero Cifuentes, Aleksandar Aleksandrov, Jacob Linacre, Pascal Vanlaer, Richard Breedon, Olmo Cerri, Saranya Ghosh, Maria Giulia Ratti, Olivier Davignon, Dmitri Konstantinov, Yacine Haddad, Conor Henderson, A. Hervé, Prasenjit Mal, Christina Snyder, Rui Zou, Angela Giraldi, Bianca Sofia Pinolini, L. S. Durkin, Souvik Das, A. Samalan, Gianni Masetti, Márton Bartók, Frans Meijers, Stephen Trembath-Reichert, Maxim Perfilov, Lucas Corcodilos, Antonin Kveton, Mauro Menichelli, A. Da Rold, Roland Horisberger, O. Gonzalez Lopez, J. Wang, Olivér Surányi, Hessamoddin Kaveh, Sascha Pascal Liechti, A. G. Stahl Leiton, Andrej Saibel, Anatoli Zarubin, Michele Arneodo, Garvita Agarwal, Federica Maria Simone, Edward Scott, Natalia Lychkovskaya, Salvatore My, Tiziano Camporesi, L. Brigliadori, Brent Stone, Seema Sharma, Sitong An, Prasant Kumar Rout, Arne Reimers, Dimitri Bourilkov, Gilvan Alves, M. Pelliccioni, Anna Teresa Meneguzzo, Kenneth Long, Andrea Carlo Marini, Francisco Yumiceva, Welathantri Gd Dharmaratna, Ritva Kinnunen, P. Chang, Darien Wood, Jyothsna Rani Komaragiri, Konstantin Shchablo, J. Pata, Ian Watson, Robert White, Timo Peltola, Michael Schmitt, Carlo Rovelli, Teruki Kamon, Dmitry Elumakhov, Ulrich Heintz, M. Kovac, Bjorn Burkle, Stephane Perries, Costas Foudas, H. Becerril Gonzalez, Konstantin Matchev, J. J. Hollar, Jean-Marie Brom, Xavier Coubez, Peter Hansen, Francisco Garcia, Basile Vermassen, Silvio Donato, Harry Cheung, Ferenc Sikler, Mario Kadastik, Alexander Dermenev, Ashley Parker, Minseok Oh, A. H. Merrit, T. A. Gómez Espinosa, A. Vorobyev, Peter Schleper, E. E. Boos, Kadri Ozdemir, Chosila Sutantawibul, Jay Mathew Lawhorn, Claude Amsler, S. Roy Chowdhury, Heriberto Castilla-Valdez, Andrea Bellora, Petar Maksimovic, Nicholas John Hadley, Zhen Hu, W. Haj Ahmad, James Dolen, Kun Shi, Zoltan Laszlo Trocsanyi, Jehad Mousa, Karl Matthew Ecklund, J. Conway, Laurent Favart, D. Del Re, Cristian Pena, Alexander Tapper, Vyacheslav Krutelyov, Bernard Ille, Ali Mohammadi, Dinko Ferencek, Caleb Smith, Chiara Aime, Giovanni Franzoni, Louise Skinnari, Nural Akchurin, Patrick Janot, Thorsten Chwalek, Daria Selivanova, Vincent Lemaitre, Deborah Pinna, K. Wichmann, P. Kyberd, Hyonsan Seo, Rachael Bucci, S. Seif El Nasr-storey, Freya Blekman, Anna Zacharopoulou, Joshuha Thomas-Wilsker, R. Lee, N. G. Redaelli, Davide Fiorina, Guido Andreassi, Paul Baillon, K. Wong, Yen-Jie Lee, Andrés G Delannoy, Christopher Hill, Gobinda Majumder, Artur Apresyan, Kevin Black, Louis Lyons, Marc Besancon, C. Chen, Dinyar Rabady, Jan Steggemann, David Michael Morse, L. Layer, S. W. Cho, Andrew Whitbeck, Viktor Veszpremi, Aliaksandr Litomin, Aliakbar Ebrahimi, Mohammadtaghi Hajheidari, Pallabi Das, Bennett Greenberg, A. Rizzi, Maral Alyari, Hannu Siikonen, Jean-Louis Faure, Riccardo Paramatti, Andrea Giammanco, Priyanka Kumari, Wolfram Dietrich Zeuner, G. Hamel de Monchenault, Kristian Harder, Hugues Lattaud, Aditee Rane, Z. Ye, Frank Jensen, Ettore Focardi, Malgorzata Kazana, Egidio Longo, David Hamilton, C. A. Salazar González, Dominique Gigi, Vilius Cepaitis, Patrick Bryant, A. Richards, Thomas Reis, Martin Lipinski, Frank Würthwein, A. Vagnerini, Raffaello D'Alessandro, Ulascan Sarica, Federico Siviero, Erhan Gülmez, Kaori Maeshima, Aurelijus Rinkevicius, Maria Toms, Anna Stakia, Martin Erdmann, E. De La Cruz-Burelo, Angela Taliercio, Manas Maity, Alexi Mestvirishvili, Andrew Wisecarver, Ulrich Goerlach, Ka Tung Lau, Leonid Didukh, S. Luo, Brieuc Francois, Christopher Rogan, Ruslan Chistov, Ying An, Massimo Casarsa, Marco Bozzo, Steve Nahn, Wren Vetens, V. Milosevic, A. Khan, V. K. Muraleedharan Nair Bindhu, Martina Malberti, Alain Givernaud, Duje Giljanovic, Nicolaus Kratochwil, I. Gonzalez Caballero, A. Benecke, Dong Ho Moon, Anton Karneyeu, M. Vander Donckt, Shabnam Jabeen, W. L. Aldá Júnior, Mauro Donegà, Igor Bayshev, V. Papadimitriou, Mikhail Kirsanov, Irene Bachiller, Luka Lambrecht, Micael Verissimo de Araujo, Patricia McBride, T. Aushev, Thomas Reitenspiess, Krzysztof Doroba, Dmytro Kovalskyi, V. Kutzner, S. Tkaczyk, D. Cutts, Matthew Kilpatrick, H. Rejeb Sfar, David Stuart, Ivan Mikulec, B. McMaster, Ddc Wickramarathna, R. Cousins, Alice Mignerey, Tommaso Tedeschi, W. Snoeys, Michael Benjamin Andrews, Dietrich Liko, Jay Dittmann, Simone Paoletti, Abhijith Gandrakota, D. Pérez Adán, Mykhailo Dalchenko, M. Lazarovits, Pawan Kumar Netrakanti, Raghunath Pradhan, Andrei Sobol, Suchandra Dutta, Anne Dabrowski, Sami Lehti, Umberto Molinatti, H. Bakhshiansohi, Jochen Schieck, Jane Nachtman, Brandon Bonham, Gabriella Pasztor, Sebastian Templ, Bryan Caraway, A. Pérez-Calero Yzquierdo, Caterina Aruta, J. Davis, J. A. Murillo Quijada, Kenichi Hatakeyama, Valentina Mariani, Dylan Rankin, Andrew Brinkerhoff, Evgueni Tcherniaev, Sébastien Wertz, Giulio Mandorli, K. A. Ulmer, K. Adamidis, D. Ramos, Thomas Ferguson, Vitalii Okhotnikov, Flavia Cetorelli, Thoth Gunter, Petar Adzic, Charis Kleio Koraka, Laura Martikainen, W. A. T. Wan Abdullah, Nikolai Golubev, Jason Gilmore, Daniele Pedrini, Tamás Álmos Vámi, Sergio F Novaes, Samet Lezki, Jose Flix, M. A. Mahmoud, Jingzhou Zhao, Branislav Ristic, Nikolas Pervan, M. Teklishyn, Balashangar Kailasapathy, C. Paus, Marco Meschini, Paolo Capiluppi, Frigyes Nemes, James Rohlf, Carlos Avila, Morgan Lethuillier, Yasar Onel, C. Mcgrady, Ka Hei Martin Kwok, Ricardo Eusebi, Salvatore Rappoccio, L. Kreczko, Alexandre Hakimi, Eric Appelt, Ivan Shvetsov, Z Warner, Stefanos Leontsinis, Savvas Kyriacou, Denis Rathjens, Claudio Caputo, Igor Golutvin, Mircho Rodozov, J. Ngadiuba, Loukas Gouskos, Frank Jm Geurts, Xuli Yan, Katherine Victoria Ellis, Marco Paganoni, Daniel Li, Smarajit Karmakar, Elizabeth Locci, Kyungwook Nam, Don Lincoln, Li Yuan, W. De Boer, Kirika Uchida, Anne-Marie Magnan, Wagner Carvalho, D. R. Claes, Marcel Rieger, Anders Ryd, Gavin Davies, Jory Sonneveld, Hafeez R Hoorani, P. Van Mechelen, A. Apyan, M. 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Mohammadi Najafabadi, Emil Sørensen Bols, Panja-Riina Luukka, Furong Yan, D. Diaz, Raffaele Gerosa, Alexander Ledovskoy, Vincent J Smith, K. Walkingshaw Pass, F. Vazzoler, Shameena Bonomally, Andrey Pozdnyakov, Roberto Salerno, Scarlet Norberg, Peter Fackeldey, R. D. Field, Olga Kodolova, Ram Krishna Dewanjee, Bora Isildak, Jonas Rübenach, Daniel Winterbottom, Thorben Quast, Weinan Si, Robert M Harris, G. Correia Silva, Gurpreet Singh Chahal, Sushrut Karmarkar, Andrew Buccilli, Marc Huwiler, Daniele Spiga, J. Alexander, G. M. Bilei, David Jonathan Hofman, Shubham Pandey, Wei Shi, O. Rieger, Thomas Klijnsma, W. S. Hou, N. Cavallo, Po-Hsun Chen, Stefano Mersi, Mykyta Haranko, Juska Pekkanen, Rohith Saradhy, M Nickel, B. Álvarez González, Krunal Gedia, Tom A. Williams, Nicola Turini, Cristina Mantilla, J. D. Ruiz Alvarez, Giacomo Bruno, Ian Mcalister, Michele Bianco, Antoine Lesauvage, W. E. Johns, D. Y. Wang, Mariana Shopova, Elham Khazaie, Eric Christian Chabert, Sandeep Bhowmik, Fengwangdong Zhang, A. Scribano, J. Van Der Linden, Boris Grynyov, Shengquan Tuo, Melanie Eich, Anna Macchiolo, Marguerite Tonjes, Kyle Cormier, David Mark Raymond, E. O. Olaiya, Christophe Delaere, J. Kaspar, Victor Kim, Armando Lanaro, Daniel Bloch, Mohamed Rashad Darwish, Giuseppe Benedetto Cerati, Dmitry Kondratyev, James D. Olsen, N. V. Krasnikov, M. G. Albrow, Deepak Kumar, J. S. Lange, Mario Maggi, Alexander Morton, Stavros Mallios, Walaa Elmetenawee, Fatma Boran, Pushpalatha C Bhat, Ilknur Hos, Arnab Purohit, Andrey Popov, Lara Zygala, B. Ribeiro Lopes, Ioannis Papakrivopoulos, Laurent Thomas, Raffaella Tramontano, Johann Rauser, M. Barroso Ferreira Filho, L. J. Gutay, V. Andreev, Grace Cummings, Francesco Fienga, C. A. Bernardes, C. Bernet, Roy Montalvo, Victor Murzin, Florian Eble, Adelina Lintuluoto, Q. Li, Katja Klein, Simon Christoph Schuler, János Karancsi, Umesh Joshi, Ashish Sharma, Marijus Ambrozas, Jared Sturdy, Doris Eckstein, Achim Geiser, Batoul Diab, Javier Cuevas, Mostafa Mahdavikhorrami, Marcello Abbrescia, Jona Motta, Theodor Christian Herwig, Sanjay Kumar, P. Tropea, Arash Jofrehei, Samuel Nathan Webb, Daniel Robert Marlow, Tahir Javaid, Roberto Mulargia, Dylan Gilbert, Giovanni Mocellin, E. Lusiani, Yves Sirois, A. M. Rossi, Toms Torims, Kousik Naskar, Th. Müller, Sarah Freed, Paul Sheldon, Alicia Calderon, Yuichi Kubota, Andreas Albert, Natale Demaria, Seyed Mohsen Etesami, Alfredo Gurrola, Ufuk Guney Tok, Abhisek Datta, Christopher Brew, Gintautas Tamulaitis, Lothar At Bauerdick, R. Loveless, Dan Brunner, Sanghyun Ko, Jennifer Ott, Byung-Sik Hong, Mahmod Moussa Abdelkhalek Gadallah, Hannes Sakulin, Tilman Rohe, Sara Nabili, M. Bluj, Michael Hildreth, Matthew Decaro, M. S. Meyer, Tanmay Sarkar, Matthew Joyce, Andrei Oskin, Ac Williams, Km Alpana, Bożena Boimska, Kerem Cankocak, Tahys Janssen, Andrew Levin, Anton Stepennov, Andrew Loeliger, Andrey Gribushin, A. Muthirakalayil Madhu, Harrison Prosper, V. Smirnov, Mario Deile, Stephen Robert Wagner, P. Priyanka, Daniele Trocino, Andreas Hinzmann, S. Chatterjee, Marcin Konecki, David Walter, Artur Lobanov, Nathaniel Pastika, Alexander Dierlamm, Michal Szleper, Chia-Ming Kuo, P. Major, Ioannis Evangelou, Filippo Errico, A. A. Bin Anuar, Nadia Pastrone, Candan Dozen, Michael Wayne Arenton, Attila József Rádl, J. Duarte, Siddhesh Sawant, Hsin-yeh Wu, G. Reales Gutiérrez, Xuyang Gao, Shalini Thakur, James John Brooke, Cédric Prieels, Brian Francis, Damir Lelas, Tamas Ferenc Csorgo, Lucas Wiens, Paolo Checchia, Alberto Messineo, Subash Chandra Behera, John Almond, P. Schütze, Michele Selvaggi, O. Behnke, Gulsen Onengut, Giacomo Sguazzoni, Z. A. Liu, Viktor Matveev, Sergio Sanchez Cruz, H. Lee, Dmitrii Kirpichnikov, Carlo Civinini, Clemens Lange, K. Sandeep, Santiago Folgueras, George Alverson, Roman Kogler, A. Bodek, Farrah Simpson, Oleksii Toldaiev, Mark Pesaresi, M. Lu, S. Shmatov, Kaitlin Salyer, F. Torres Da Silva De Araujo, Daniele Ruini, Michail Bachtis, Oleg Filatov, Jean-Baptiste Sauvan, Gigi Rolandi, Thomas Schuh, Stefano Argiro, Bennett Marsh, L. Urda Gómez, Markus Seidel, Vineet Kumar, Michael Krohn, Piotr Zalewski, C. Kleinwort, Zhenbin Wu, Bhawna Gomber, Marcello Mannelli, Christian Schwanenberger, Francesco Brivio, Nuno Leonardo, C-E Wulz, Andris Skuja, Ivica Puljak, Hans Reithler, Ben Bylsma, Roberto Tenchini, Ashutosh Bhardwaj, J. O. Gosewisch, Meng Xiao, Jacobo Konigsberg, Bryan Cardwell, Giacomo Boldrini, J. Anguiano, Y. Musienko, Henri Petrow, M. C. Fouz, Lukas Lechner, B. Maier, Lata Panwar, Peter Raics, Peicho Petkov, Sridhara Dasu, Emilio Meschi, Shaun Hogan, W. T. Lin, Raman Khurana, Aliya Nigamova, Alexandros Attikis, Erik Brücken, Achille Petrilli, G. Ortona, Bradley Cox, Colin Jessop, Changwoo Joo, Alessandro Calandri, M. Calderon De La Barca Sanchez, A. C. Bundock, Matthias Kasemann, Luca Giommi, Cole Lindsey, V. Makarenko, Sushil Chauhan, Paola Salvini, Florian Beaudette, Kajari Mazumdar, Hao Wang, Daniel Arcaro, Christina Wang, Shudhashil Bharthuar, Andrea Gelmi, B. Tali, Luigi Guiducci, Gregory R Snow, Igor Volobouev, Hirak Bandyopadhyay, Özlem Özçelik, Genady Gavrilov, Marcus Hohlmann, Sharad Malik, Byeonghak Ko, Carlos Florez, D. A. Perez Navarro, Ilaria Vai, Nicolas Postiau, Siqi Yuan, C. S. Moon, J. Mejia Guisao, Geetanjali Chaudhary, Evan Koenig, Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), CMS, Sağır, Sinan, Universidad de Cantabria, Physics, Elementary Particle Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, CMS Collaboration, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Department of Physics, Helsinki Institute of Physics, Armen, Tumasyan, Iorio, A. 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Estrada C., Mijuskovic J., Raicevic N., Krofcheck D., Butler P.H., Ahmad A., Asghar M.I., Awais A., Awan M.I.M., Hoorani H.R., Khan W.A., Shah M.A., Shoaib M., Waqas M., Avati V., Grzanka L., Malawski M., Bialkowska H., Bluj M., Boimska B., Gorski M., Kazana M., Szleper M., Zalewski P., Bunkowski K., Doroba K., Kalinowski A., Konecki M., Krolikowski J., Araujo M., Bargassa P., Bastos D., Boletti A., Faccioli P., Gallinaro M., Hollar J., Leonardo N., Niknejad T., Pisano M., Seixas J., Toldaiev O., Varela J., Afanasiev S., Budkouski D., Golutvin I., Gorbunov I., Karjavine V., Korenkov V., Lanev A., Malakhov A., Matveev V., Palichik V., Perelygin V., Savina M., Seitova D., Shalaev V., Shmatov S., Shulha S., Smirnov V., Teryaev O., Voytishin N., Yuldashev B.S., Zarubin A., Zhizhin I., Gavrilov G., Golovtcov V., Ivanov Y., Kim V., Kuznetsova E., Murzin V., Oreshkin V., Smirnov I., Sosnov D., Sulimov V., Uvarov L., Volkov S., Vorobyev A., Andreev Y., Dermenev A., Gninenko S., Golubev N., Karneyeu A., Kirpichnikov D., Kirsanov M., Krasnikov N., Pashenkov A., Pivovarov G., Toropin A., Epshteyn V., Gavrilov V., Lychkovskaya N., Nikitenko A., Popov V., Stepennov A., Toms M., Vlasov E., Zhokin A., Aushev T., Bychkova O., Chistov R., Danilov M., Oskin A., Polikarpov S., Selivanova D., Andreev V., Azarkin M., Dremin I., Kirakosyan M., Terkulov A., Belyaev A., Boos E., Bunichev V., Dubinin M., Dudko L., Gribushin A., Klyukhin V., Kodolova O., Lokhtin I., Obraztsov S., Perfilov M., Savrin V., Snigirev A., Blinov V., Dimova T., Kardapoltsev L., Kozyrev A., Ovtin I., Skovpen Y., Azhgirey I., Bayshev I., Elumakhov D., Kachanov V., Konstantinov D., Mandrik P., Petrov V., Ryutin R., Slabospitskii S., Sobol A., Troshin S., Tyurin N., Uzunian A., Volkov A., Babaev A., Okhotnikov V., Borshch V., Ivanchenko V., Tcherniaev E., Adzic P., Dordevic M., Milenovic P., Milosevic J., Aguilar-Benitez M., Alcaraz Maestre J., Alvarez Fernandez A., Bachiller I., Barrio Luna M., Bedoya C.F., Carrillo Montoya C.A., Cepeda M., Cerrada M., Colino N., De La Cruz B., Delgado Peris A., Fernandez Ramos J.P., Flix J., Fouz M.C., Gonzalez Lopez O., Goy Lopez S., Hernandez J.M., Josa M.I., Leon Holgado J., Moran D., Navarro Tobar A., Perez Dengra C., Perez-Calero Yzquierdo A., Puerta Pelayo J., Redondo I., Romero L., Sanchez Navas S., Urda Gomez L., Willmott C., de Troconiz J.F., Reyes-Almanza R., Alvarez Gonzalez B., Cuevas J., Erice C., Fernandez Menendez J., Folgueras S., Gonzalez Caballero I., Gonzalez Fernandez J.R., Palencia Cortezon E., Ramon Alvarez C., Rodriguez Bouza V., Soto Rodriguez A., Trapote A., Trevisani N., Vico Villalba C., Brochero Cifuentes J.A., Cabrillo I.J., Calderon A., Duarte Campderros J., Fernandez M., Fernandez Madrazo C., Fernandez Manteca P.J., Garcia Alonso A., Gomez G., Martinez Rivero C., Martinez Ruiz del Arbol P., Matorras F., Matorras-Cuevas P., Piedra Gomez J., Prieels C., Rodrigo T., Ruiz-Jimeno A., Scodellaro L., Vila I., Vizan Garcia J.M., 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R., Zhu D.H., Amsler C., Bartschi P., Botta C., Brzhechko D., Canelli M.F., Cormier K., De Wit A., Del Burgo R., Heikkila J.K., Huwiler M., Jin W., Jofrehei A., Kilminster B., Leontsinis S., Liechti S.P., Macchiolo A., Meiring P., Mikuni V.M., Molinatti U., Neutelings I., Reimers A., Robmann P., Sanchez Cruz S., Schweiger K., Takahashi Y., Adloff C., Kuo C.M., Lin W., Roy A., Sarkar T., Yu S.S., Ceard L., Chao Y., Chen K.F., Chen P.H., Hou W.-S., Li Y., Lu R.-S., Paganis E., Psallidas A., Steen A., Wu H., Yazgan E., Yu P., Asavapibhop B., Asawatangtrakuldee C., Srimanobhas N., Boran F., Damarseckin S., Demiroglu Z.S., Dolek F., Dumanoglu I., Eskut E., Guler Y., Gurpinar Guler E., Isik C., Kara O., Kayis Topaksu A., Kiminsu U., Onengut G., Ozdemir K., Polatoz A., Simsek A.E., Tali B., Tok U.G., Turkcapar S., Zorbakir I.S., Zorbilmez C., Isildak B., Karapinar G., Ocalan K., Yalvac M., Akgun B., Atakisi I.O., Gulmez E., Kaya M., Kaya O., Ozcelik O., Tekten S., Yetkin E.A., Cakir A., 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J.R., Wang C., Xie S., Zhang Z., Zhu R.Y., Alison J., An S., Andrews M.B., Bryant P., Ferguson T., Harilal A., Liu C., Mudholkar T., Paulini M., Sanchez A., Terrill W., Cumalat J.P., Ford W.T., Hassani A., MacDonald E., Patel R., Perloff A., Savard C., Stenson K., Ulmer K.A., Wagner S.R., Alexander J., Bright-thonney S., Cheng Y., Cranshaw D.J., Hogan S., Monroy J., Patterson J.R., Quach D., Reichert J., Reid M., Ryd A., Sun W., Thom J., Wittich P., Zou R., Albrow M., Alyari M., Apollinari G., Apresyan A., Apyan A., Bauerdick L.A.T., Berry D., Berryhill J., Bhat P.C., Burkett K., Butler J.N., Canepa A., Cerati G.B., Cheung H.W.K., Chlebana F., Cremonesi M., Di Petrillo K.F., Elvira V.D., Feng Y., Freeman J., Gecse Z., Gray L., Green D., Grunendahl S., Gutsche O., Harris R.M., Heller R., Herwig T.C., Hirschauer J., Jayatilaka B., Jindariani S., Johnson M., Joshi U., Klijnsma T., Klima B., Kwok K.H.M., Lammel S., Lincoln D., Lipton R., Liu T., Madrid C., Maeshima K., Mantilla C., Mason 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Wamorkar T., Wang B., Wisecarver A., Wood D., Bueghly J., Chen Z., Gilbert A., Gunter T., Hahn K.A., Liu Y., Odell N., Schmitt M.H., Velasco M., Band R., Bucci R., Das A., Dev N., Goldouzian R., Hildreth M., Hurtado Anampa K., Jessop C., Lannon K., Lawrence J., Loukas N., Lutton D., Marinelli N., Mcalister I., McCauley T., Mcgrady C., Mohrman K., Musienko Y., Ruchti R., Siddireddy P., Townsend A., Wayne M., Wightman A., Zarucki M., Zygala L., Bylsma B., Cardwell B., Durkin L.S., Francis B., Hill C., Nunez Ornelas M., Wei K., Winer B.L., Yates B.R., Addesa F.M., Bonham B., Das P., Dezoort G., Elmer P., Frankenthal A., Greenberg B., Haubrich N., Higginbotham S., Kalogeropoulos A., Kopp G., Kwan S., Lange D., Marlow D., Mei K., Ojalvo I., Olsen J., Stickland D., Tully C., Norberg S., Bakshi A.S., Barnes V.E., Chawla R., Das S., Gutay L., Jones M., Jung A.W., Karmarkar S., Kondratyev D., Liu M., Negro G., Neumeister N., Paspalaki G., Piperov S., Purohit A., Schulte J.F., Stojanovic M., 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Padeken K., Romeo F., Sheldon P., Tuo S., Velkovska J., Arenton M.W., Cox B., Cummings G., Hakala J., Hirosky R., Joyce M., Ledovskoy A., Li A., Neu C., Perez Lara C.E., Tannenwald B., White S., Wolfe E., Poudyal N., Black K., Bose T., Caillol C., Dasu S., De Bruyn I., Everaerts P., Fienga F., Galloni C., He H., Herndon M., Herve A., Hussain U., Lanaro A., Loeliger A., Loveless R., Madhusudanan Sreekala J., Mallampalli A., Mohammadi A., Pinna D., Savin A., Shang V., Smith W.H., Teague D., Trembath-Reichert S., Vetens W., Yerevan Physics Institute, Institut für Hochenergiephysik, Institute for Nuclear Problems, Universiteit Antwerpen, Vrije Universiteit Brussel, Université Libre de Bruxelles, Ghent University, Université Catholique de Louvain, Centro Brasileiro de Pesquisas Fisicas, Universidade do Estado do Rio de Janeiro (UERJ), Universidade Estadual Paulista (UNESP), Universidade Federal do ABC (UFABC), Bulgarian Academy of Sciences, University of Sofia, Beihang University, Tsinghua University, Institute of High Energy Physics, Peking University, Sun Yat-Sen University, Institute of Modern Physics and Key Laboratory of Nuclear Physics and Ion- beam Application (MOE) — Fudan University, Zhejiang University, Universidad de Los Andes, Universidad de Antioquia, Mechanical Engineering and Naval Architecture, Faculty of Science, Institute Rudjer Boskovic, University of Cyprus, Charles University, Escuela Politecnica Nacional, Universidad San Francisco de Quito, Egyptian Network of High Energy Physics, Fayoum University, National Institute of Chemical Physics and Biophysics, University of Helsinki, Lappeenranta University of Technology, Université Paris-Saclay, Institut Polytechnique de Paris, IPHC UMR 7178, Institut de Physique des 2 Infinis de Lyon (IP2I), Georgian Technical University, I.Physikalisches Institut, III.Physikalisches Institut A, III.Physikalisches Institut B, Deutsches Elektronen-Synchrotron, University of Hamburg, Karlsruher Institut fuer Technologie, NCSR Demokritos, National and Kapodistrian University of Athens, National Technical University of Athens, University of Ioánnina, Eötvös Loránd University, Wigner Research Centre for Physics, Institute of Nuclear Research ATOMKI, University of Debrecen, MATE Institute of Technology, Indian Institute of Science (IISc), HBNI, Panjab University, University of Delhi, Indian Institute of Technology Madras, Bhabha Atomic Research Centre, Tata Institute of Fundamental Research-A, Tata Institute of Fundamental Research-B, Indian Institute of Science Education and Research (IISER), Isfahan University of Technology, Institute for Research in Fundamental Sciences (IPM), University College Dublin, INFN Sezione di Bari, Università di Bari, Politecnico di Bari, INFN Sezione di Bologna, Università di Bologn, INFN Sezione di Catania, Università di Catania, INFN Sezione di Firenze, Università di Firenz, INFN Laboratori Nazionali di Frascati, INFN Sezione di Genova, Università di Genova, INFN Sezione di Milano-Bicocca, Università di Milano-Bicocca, INFN Sezione di Napoli, Università di Napoli ‘Federico II’, Università della Basilicata, Università G.Marconi, INFN Sezione di Padova, Università di Padova, INFN Sezione di Pavia, Università di Pavia, INFN Sezione di Perugia, Università di Perugia, INFN Sezione di Pisa, Università di Pisa, Scuola Normale Superiore di Pisa, Università di Siena, INFN Sezione di Roma, Sapienza Università di Roma, INFN Sezione di Torino, Università di Torino, Università del Piemonte Orientale, INFN Sezione di Trieste, Università di Trieste, Kyungpook National University, Institute for Universe and Elementary Particles, Hanyang University, Korea University, Kyung Hee University, Sejong University, Seoul National University, University of Seoul, Yonsei University, Sungkyunkwan University, American University of the Middle East (AUM), Riga Technical University, Vilnius University, Universiti Malaya, Universidad de Sonora (UNISON), Centro de Investigacion y de Estudios Avanzados del IPN, Universidad Iberoamericana, Benemerita Universidad Autonoma de Puebla, University of Montenegro, University of Auckland, University of Canterbury, Quaid-I-Azam University, Electronics and Telecommunications, National Centre for Nuclear Research, University of Warsaw, Laboratório de Instrumentação e Física Experimental de Partículas, Joint Institute for Nuclear Research, Petersburg Nuclear Physics Institute, Institute for Nuclear Research, Institute for Theoretical and Experimental Physics named by A.I.Alikhanov of NRC ‘Kurchatov Institute’, Moscow Institute of Physics and Technology, National Research Nuclear University ‘Moscow Engineering Physics Institute’ (MEPhI), P.N.Lebedev Physical Institute, Lomonosov Moscow State University, Novosibirsk State University (NSU), Institute for High Energy Physics of National Research Centre ‘Kurchatov Institute’, National Research Tomsk Polytechnic University, Tomsk State University, University of Belgrade: Faculty of Physics and VINCA Institute of Nuclear Sciences, Centro de Investigaciones Energéticas Medioambientales y Tecnológicas (CIEMAT), Universidad Autónoma de Madrid, Instituto Universitario de Ciencias y Tecnologías Espaciales de Asturias (ICTEA), CSIC-Universidad de Cantabria, University of Colombo, University of Ruhuna, Paul Scherrer Institut, ETH Zurich — Institute for Particle Physics and Astrophysics (IPA), Universität Zürich, National Central University, National Taiwan University (NTU), Science and Art Faculty, Physics Department, Bogazici University, Istanbul Technical University, Istanbul University, Institute for Scintillation Materials of National Academy of Science of Ukraine, Kharkov Institute of Physics and Technology, University of Bristol, Rutherford Appleton Laboratory, Imperial College, Brunel University, Baylor University, Catholic University of America, The University of Alabama, Boston University, Brown University, Davis, University of California, Riverside, Santa Barbara — Department of Physics, California Institute of Technology, Carnegie Mellon University, University of Colorado Boulder, Cornell University, Fermi National Accelerator Laboratory, University of Florida, Florida State University, Florida Institute of Technology, University of Illinois at Chicago (UIC), The University of Iowa, Johns Hopkins University, The University of Kansas, Kansas State University, Lawrence Livermore National Laboratory, University of Maryland, Massachusetts Institute of Technology, University of Minnesota, University of Nebraska-Lincoln, State University of New York at Buffalo, Northeastern University, Northwestern University, University of Notre Dame, The Ohio State University, Princeton University, University of Puerto Rico, Purdue University, Purdue University Northwest, Rice University, University of Rochester, The State University of New Jersey, University of Tennessee, Texas A&M University, Texas Tech University, Vanderbilt University, University of Virginia, Wayne State University, University of Wisconsin — Madison, TU Wien, Technology and Maritime Transport, Universidade Estadual de Campinas (UNICAMP), Federal University of Rio Grande do Sul, The University of the State of Amazonas, University of Chinese Academy of Sciences, Universidade Federal de Mato Grosso do Sul (UFMS), Nanjing Normal University Department of Physics, British University in Egypt, Zewail City of Science and Technology, Université de Haute Alsace, Erzincan Binali Yildirim University, Brandenburg University of Technology, Forschungszentrum Jülich, Assiut University, IIT Bhubaneswar, Institute of Physics, G.H.G.Khalsa College, Shoolini University, University of Hyderabad, University of Visva-Bharati, Indian Institute of Technology (IIT), Sharif University of Technology, University of Science and Technology of Mazandaran, Energy and Sustainable Economic Development, Centro Siciliano di Fisica Nucleare e di Struttura Della Materia, Consiglio Nazionale delle Ricerche — Istituto Officina dei Materiali, Consejo Nacional de Ciencia y Tecnología, Institute of Nuclear Physics of the Uzbekistan Academy of Sciences, St.Petersburg State Polytechnical University, Budker Institute of Nuclear Physics, University of Belgrade, Sri Lanka, Ecole Polytechnique Fédérale Lausanne, Stefan Meyer Institute for Subatomic Physics, IN2P3-CNRS, Şırnak University, Research Center of Experimental Health Science, Konya Technical University, Piri Reis University, Adiyaman University, Ozyegin University, Izmir Institute of Technology, Necmettin Erbakan University, Bozok Universitetesi Rektörlügü, Marmara University, Kafkas University, Istanbul Bilgi University, Hacettepe University, Faculty of Engineering, University of Southampton, IPPP Durham University, Bethel University, Karamanoğlu Mehmetbey University, Ain Shams University, Bingol University, Sinop University, Erciyes University, Texas A&M University at Qatar, Università di Trento, Milli Savunma University, CERN, and Damarseçkin, serdal
Subjects: transverse momentum: missing-energy, 13000 GeV-cms, (experiments), QC770-798, 01 natural sciences, Physics, Particles & Fields, Hadron-Hadron scattering (experiments), scattering [p p], Z0: hadronic decay, Large Hadron Collider, Luminosity (scattering theory), Beyond Standard Model, Dark matter, Hadron-Hadron scattering, Higgs physics, DARK-MATTER, HIGGS, Physics, upper limit [coupling constant], mass dependence, CERN LHC Coll, Higgs particle: branching ratio: upper limit, Physical Sciences, Higgs boson, PARTICLE PHYSICS, Neutrino, colliding beams [p p], p p: scattering, +quark+neutrino%22">leptoquark --> quark neutrino, coupling constant: upper limit, branching ratio: upper limit [Higgs particle], vector [coupling], 114 Physical sciences, Standard Model, coupling [dark matter], scalar [leptoquark], ddc:530, 010306 general physics, initial state, 0206 Quantum Physics, space-time: higher-dimensional, W: hadronic decay, Science & Technology, coupling: vector, 010308 nuclear & particles physics, Branching fraction, LARGE HADRON COLLIDER, CMS, cross section: ratio: upper limit, spin [dark matter], p p: colliding beams, invisible decay [Higgs particle], new particle, ComputerSystemsOrganization_COMPUTERSYSTEMIMPLEMENTATION, High Energy Physics - Experiment, dark matter: coupling, High Energy Physics - Experiment (hep-ex), ComputingMilieux_COMPUTERSANDEDUCATION, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], 0105 Mathematical Physics, Hadron-Hadron scattering (experi-ments), hadronic decay [Z0], Settore FIS/01 - Fisica Sperimentale, leptoquark: scalar, initial-state interaction [radiation], Nuclear & Particles Physics, category, High energy physics, Experimental particle physics, LHC, Radiation-hard detectors, Si microstrip and pad detectors, Radiation damage to detector materials (solid state), Particle tracking detectors (Solid-state detectors), radiation: damage, CMS: upgrade, tracking detector, semiconductor detector: design, semiconductor detector: microstrip, performance, Top physics, top: single production, 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Large extra dimension, Particle Physics - Experiment, Nuclear and High Energy Physics, Particle physics, data analysis method, neural network, FOS: Physical sciences, Higgs particle: invisible decay, statistical analysis, Nuclear and particle physics. Atomic energy. Radioactivity, 0103 physical sciences, dark matter: spin, ratio: upper limit [cross section], radiation: initial-state interaction, coupling: pseudoscalar, hadronic decay [W], higher-dimensional [space-time], ComputingMilieux_THECOMPUTINGPROFESSION, hep-ex, background, High Energy Physics::Phenomenology, mediation [dark matter], Beyond standard model, pseudoscalar [coupling], dark matter: mediation, Physics and Astronomy, missing-energy [transverse momentum], High Energy Physics::Experiment, experimental results
Abstract: CMS Collaboration: et al., A search is presented for new particles produced at the LHC in proton-proton collisions at s√ = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb−1, collected in 2017–2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb−1, collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date., Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract Nos. 675440, 724704, 752730, 758316, 765710, 824093, and COST Action CA16108 (European Union); CERN; the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia María de Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias.
Published: 2021

39. Educational Leadership and Critical Theory : What Can School Leaders Learn From the Critical Theorists

Author: Charles L. Lowery, Chetanath Gautam, Robert White, Michael E. Hess, Charles L. Lowery, Chetanath Gautam, Robert White, and Michael E. Hess
Subjects: Critical theory, Critical pedagogy, Educational leadership--Philosophy, Educational change, Educational leadership
Abstract: This book shows how critical theory can help school leaders and administrators to prepare students for the ever-changing political, cultural, economic, and societal conditions of the world. The contributors use ideas from critical theorists including Adorno, Fromm, Marcuse and Habermas and connect them with contemporary theories and debates in educational leadership from moral education to criticaltheories on race, to culturally relevant practice.Educational Leadership and Critical Theory challenges the misconceptions of many present-day educators about the analytical lens offered by the Frankfurt School theorists which is often dismissed by policymakers and practitioners. Written by leading scholars based in the UK, USA, and Canada, the contributors emphasize and explain the importance of educational aesthetics, dialectics, education and civilization, the structural transformation of education's place in the public sphere, and education as revolution and enlightenment.
Published: 2024

40. Shakespeare Against War: Pacifist Readings

Author: Robert White and Robert White
Subjects: Pacifism in literature, Peace in literature
Abstract: Whilst Shakespearean drama provides eloquent calls to war, more often than not these are undercut or outweighed by compelling appeals to peaceful alternatives conveyed through narrative structure, dramatic context and poetic utterance. Placing Shakespeare's works in the history of pacifist thought, Robert White argues that Shakespeare's plays consistently challenge appeals to heroism and revenge and reveal the brutal futility of war. White also examines Shakespeare's interest in the mental states of military officers when their ingrained training is tested in love relationships. In imagery and themes, war infiltrates love, with problematical consequences, reflected in Shakespeare's comedies, histories and tragedies alike. Challenging a critical orthodoxy that military engagement in war is an inevitable and necessary condition, White draws analogies with the experience of modern warfare, showing the continuing relevance of Shakespeare's plays which deal with basic issues of war and peace that are still evident.
Published: 2024

41. Italian Theatre Since the War

Author: Pandolfi, Vito, Rizzo, Gino, and Linker, Robert White
Published: 1964
Full Text: View/download PDF

42. François Villon: Murderer or Poet?

Author: Linker, Robert White
Published: 1973
Full Text: View/download PDF

43. The Moral Case for Profit Maximization

Author: Robert White and Robert White
Subjects: Business ethics, Profit--Moral and ethical aspects, Profit--Philosophy
Abstract: The Moral Case for Profit Maximization argues that profit maximization is moral when businessmen seek to maximize profit by creating goods or services that are of objective value. Traditionally, profit maximization has been defended on economic grounds. Profit, economists argue, incentivizes businessmen to produce goods and services. In this view, businessmen do not need to be virtuous as long as they deliver the goods. It challenges the traditional defense of profit maximization, arguing that profit maximization is morally ambitious because it requires businessmen to form normative abstractions and to cultivate a virtuous character. In so doing, the author also challenges the moral basis of corporate social responsibility. Proponents of CSR argue that businessmen can do good while doing well. This book argues that businessmen already do good by maximizing profit, drawing upon the histories of the wheel, the refrigerator, and the shipping container, as well as the biographies of J. P. Morgan, John D. Rockefeller, and Thomas Edison to demonstrate the role of values in the creation of material goods and the role of the virtues in value creation. The author challenges readers to rethink the relationship between profit, value, and virtue.
Published: 2020

44. What Good Is God? : Crises, Faith, and Resilience

Author: Roger Abbott, Robert White FRS, Roger Abbott, and Robert White FRS
Subjects: Faith, Disasters--Religious aspects--Christianity, Resilience (Personality trait)--Religious aspects--Christianity
Abstract: In a world where natural disasters are increasingly impacting our lives, this insightful book brings together a variety of voices to discuss how we can respond practically and faithfully to such tragedies. Consciously making room for the perspectives of survivors, responders, and academics, it provides a multi-layered and compassionate examination of a difficult and often underexplored subject. As we try to make sense of a seemingly chaotic world that features earthquakes, tsunamis, and pandemics, readers will find this unique conversation a truly ispiring resource for thought, prayer, and action.
Published: 2020

45. Keats's Anatomy of Melancholy

Author: Robert White and Robert White
Subjects: Melancholy in literature
Abstract: This book examines John Keats's immensely important collection of poems, Lamia, Isabella, The Eve of St Agnes, And Other Poems (1820), and is published in the volume's bicentenary.
Published: 2020

46. How primary care can contribute to good mental health in adults

Author: Laura Nasir, Kurt C. Stange, Sunjai Gupta, John I. Spicer, Steve Thomas, Gina Giotaki, Tony Burch, Robert White, Baljeet Ruprah-Shah, Fiona Wright, Lise Hertel, Brian Fisher, Rachel Jenkins, Catherine Millington-Sanders, David Morris, Ricky Banarsee, Paul G. Thomas, Nigel Mathers, and Marina Marks
Subjects: 030506 rehabilitation, education.field_of_study, Population, Public Health, Environmental and Occupational Health, Review: Opinion and Debate, Primary care, Accountable care organisations, Mental health, collaboration, primary care, 03 medical and health sciences, 0302 clinical medicine, Alliance, Nursing, C848, 030212 general & internal medicine, Early childhood, 0305 other medical science, education, Psychology
Abstract: The need for support for good mental health is enormous. General support for good mental health is needed for 100% of the population, and at all stages of life, from early childhood to end of life. Focused support is needed for the 17.6% of adults who have a mental disorder at any time, including those who also have a mental health problem amongst the 30% who report having a long-term condition of some kind. All sectors of society and all parts of the NHS need to play their part. Primary care cannot do this on its own. This paper describes how primary care practitioners can help stimulate such a grand alliance for health, by operating at four different levels – as individual practitioners, as organisations, as geographic clusters of organisations and as policy-makers.
Published: 2018

47. Venture Capital Term Sheets

Author: Ramana Nanda, Robert White, William A. Sahlman, Ramana Nanda, Robert White, and William A. Sahlman
Published: 2018

48. Bootstrapping at Lightricks

Author: Christine Snively, Jeffrey J. Bussgang, Robert White, Christine Snively, Jeffrey J. Bussgang, and Robert White
Abstract: By August 2015, two-year-old mobile imaging software startup Lightricks had developed and released two best-selling paid mobile apps, grown to a team of 30, earned a revenue run rate of nearly $10 million, and achieved modest profitability. The bootstrapped company had explored raising funds, met with venture capital firms, and was presented with a term sheet. The co-founders believed the financing would allow them to scale up quicker, but they also worried about losing control of their company.
Published: 2017

49. The Outsourcing Manual

Author: Robert White, Barry James, Robert White, and Barry James
Subjects: Contracting out, Project management
Abstract: Large companies and small are increasingly seeing outsourcing as a means of making the most of their more limited resources. But how do you know whether it is right for your organization? What benefits are on offer and how do you ensure you realize them? How do you begin to construct a value-for-money agreement or determine a basis for pricing? What are the risks, and how do you recognize and manage them? Because every organization's needs are different, informed answers to these questions have been difficult to come by. Robert White and Barry James are experts with more than 35 years of experience in this field. The Outsourcing Manual is a fully comprehensive guide for any organization considering taking this route. It is above all practical, with models, outline procedures, a step-by-step guide to procurement, and standard documentation that can easily be adapted to your organization's requirements. There are case studies and worked examples throughout. The four part structure takes you through: assessment of outsourcing as a strategy for your organization; the planning phase; implementation; and outsourcing from the supplier's perspective. If you are involved in or considering outsourcing, the methodical and case study illustrated approach of The Outsourcing Manual will equip you to manage the process for a successful outcome.
Published: 2017

50. Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy : Advances in Diagnosis and Treatment

Author: Hans Forssberg, Andrea Guzzetta, James A Blackman, Giovanni Cioni, Alicia J Spittle, Marelle Thornton, Nathalie L. Maitre, Mijna Hadders-Algra, Ann-Christin Eliasson, Janice E. Brunstrom-Hernandez, Robert White, Garey Noritz, Sarah McIntyre, Donna M. Ferriero, Lindsay Pennington, Petra Karlsson, Christa Einspieler, Simona Fiori, Diane L. Damiano, Linda Fetters, Jane Valentine, Beatrice Latal, Lena Krumlinde-Sundholm, Karen Walker, Regina T. Harbourne, Linda S. de Vries, Andrew M. Gordon, Johanna Darrah, Roberta B. Shepherd, Iona Novak, Nadia Badawi, Roslyn N. Boyd, Darcy Fehlings, Catherine Morgan, Susan Greaves, Domenico M. Romeo, Alison Loughran-Fowlds, Angelina Kakooza-Mwesige, Michael T. Fahey, and Lars Adde
Subjects: General movements assessment, Pediatrics, medicine.medical_specialty, Neurology, Neurological examination, Cochrane Library, Cerebral palsy, law.invention, 03 medical and health sciences, 0302 clinical medicine, Settore MED/39 - NEUROPSICHIATRIA INFANTILE, Randomized controlled trial, law, 030225 pediatrics, medicine, Journal Article, Medical history, cerebral palsy, medicine.diagnostic_test, business.industry, medicine.disease, Systematic review, Pediatrics, Perinatology and Child Health, Physical therapy, business, 030217 neurology & neurosurgery
Abstract: Importance Cerebral palsy describes the most common physical disability in childhood and occurs in 1 in 500 live births. Historically, the diagnosis has been made between age 12 and 24 months but now can be made before 6 months’ corrected age. Objectives To systematically review best available evidence for early, accurate diagnosis of cerebral palsy and to summarize best available evidence about cerebral palsy–specific early intervention that should follow early diagnosis to optimize neuroplasticity and function. Evidence Review This study systematically searched the literature about early diagnosis of cerebral palsy in MEDLINE (1956-2016), EMBASE (1980-2016), CINAHL (1983-2016), and the Cochrane Library (1988-2016) and by hand searching. Search terms included cerebral palsy , diagnosis , detection , prediction , identification , predictive validity , accuracy , sensitivity , and specificity . The study included systematic reviews with or without meta-analyses, criteria of diagnostic accuracy, and evidence-based clinical guidelines. Findings are reported according to the PRISMA statement, and recommendations are reported according to the Appraisal of Guidelines, Research and Evaluation (AGREE) II instrument. Findings Six systematic reviews and 2 evidence-based clinical guidelines met inclusion criteria. All included articles had high methodological Quality Assessment of Diagnostic Accuracy Studies (QUADAS) ratings. In infants, clinical signs and symptoms of cerebral palsy emerge and evolve before age 2 years; therefore, a combination of standardized tools should be used to predict risk in conjunction with clinical history. Before 5 months’ corrected age, the most predictive tools for detecting risk are term-age magnetic resonance imaging (86%-89% sensitivity), the Prechtl Qualitative Assessment of General Movements (98% sensitivity), and the Hammersmith Infant Neurological Examination (90% sensitivity). After 5 months’ corrected age, the most predictive tools for detecting risk are magnetic resonance imaging (86%-89% sensitivity) (where safe and feasible), the Hammersmith Infant Neurological Examination (90% sensitivity), and the Developmental Assessment of Young Children (83% C index). Topography and severity of cerebral palsy are more difficult to ascertain in infancy, and magnetic resonance imaging and the Hammersmith Infant Neurological Examination may be helpful in assisting clinical decisions. In high-income countries, 2 in 3 individuals with cerebral palsy will walk, 3 in 4 will talk, and 1 in 2 will have normal intelligence. Conclusions and Relevance Early diagnosis begins with a medical history and involves using neuroimaging, standardized neurological, and standardized motor assessments that indicate congruent abnormal findings indicative of cerebral palsy. Clinicians should understand the importance of prompt referral to diagnostic-specific early intervention to optimize infant motor and cognitive plasticity, prevent secondary complications, and enhance caregiver well-being.
Published: 2017

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