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414 results on '"Ripoli, Andrea"'

7. Identification of COVID-19 patients at risk of hospital admission and mortality: a European multicentre retrospective analysis of mid-regional pro-adrenomedullin

Author

Sozio, Emanuela, Moore, Nathan A., Fabris, Martina, Ripoli, Andrea, Rumbolo, Francesca, Minieri, Marilena, Boverio, Riccardo, Rodríguez Mulero, María Dolores, Lainez-Martinez, Sara, Martínez Martínez, Mónica, Calvo, Dolores, Gregoriano, Claudia, Williams, Rebecca, Brazzi, Luca, Terrinoni, Alessandro, Callegari, Tiziana, Hernández Olivo, Marta, Esteban-Torrella, Patricia, Calcerrada, Ismael, Bernasconi, Luca, Kidd, Stephen P., Sbrana, Francesco, Miguens, Iria, Gordon, Kirsty, Visentini, Daniela, Legramante, Jacopo M., Bassi, Flavio, Cortes, Nicholas, Montrucchio, Giorgia, Di Lecce, Vito N., Lauritano, Ernesto C., García de Guadiana-Romualdo, Luis, González del Castillo, Juan, Bernal-Morell, Enrique, Andaluz-Ojeda, David, Schuetz, Philipp, Curcio, Francesco, Tascini, Carlo, and Saeed, Kordo

Published
2022
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10. MR-proADM as prognostic factor of outcome in COVID-19 patients

Author

Sozio, Emanuela, Tascini, Carlo, Fabris, Martina, D’Aurizio, Federica, De Carlo, Chiara, Graziano, Elena, Bassi, Flavio, Sbrana, Francesco, Ripoli, Andrea, Pagotto, Alberto, Giacinta, Alessandro, Gerussi, Valentina, Visentini, Daniela, De Stefanis, Paola, Merelli, Maria, Saeed, Kordo, and Curcio, Francesco

Published
2021
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12. Head-to-head comparison of plasma cTnI concentration values measured with three high-sensitivity methods in a large Italian population of healthy volunteers and patients admitted to emergency department with acute coronary syndrome: A multi-center study

Author

Clerico, Aldo, Ripoli, Andrea, Zaninotto, Martina, Masotti, Silvia, Musetti, Veronica, Ciaccio, Marcello, Aloe, Rosalia, Rizzardi, Sara, Dittadi, Ruggero, Carrozza, Cinzia, Fasano, Tommaso, Perrone, Marco, de Santis, Antonio, Prontera, Concetta, Riggio, Daniela, Guiotto, Cristina, Migliardi, Marco, Bernardini, Sergio, and Plebani, Mario

Published
2019
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13. sST2 Predicts Outcome in Chronic Heart Failure Beyond NT−proBNP and High-Sensitivity Troponin T

Author

Emdin, Michele, Aimo, Alberto, Vergaro, Giuseppe, Bayes-Genis, Antoni, Lupón, Josep, Latini, Roberto, Meessen, Jennifer, Anand, Inder S., Cohn, Jay N., Gravning, Jørgen, Gullestad, Lars, Broch, Kaspar, Ueland, Thor, Nymo, Ståle H., Brunner-La Rocca, Hans-Peter, de Boer, Rudolf A., Gaggin, Hanna K., Ripoli, Andrea, Passino, Claudio, and Januzzi, James L., Jr.

Published
2018
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16. Meta-Analysis of Soluble Suppression of Tumorigenicity-2 and Prognosis in Acute Heart Failure

Author

Aimo, Alberto, Vergaro, Giuseppe, Ripoli, Andrea, Bayes-Genis, Antoni, Pascual Figal, Domingo A., de Boer, Rudolf A., Lassus, Johan, Mebazaa, Alexandre, Gayat, Etienne, Breidthardt, Tobias, Sabti, Zaid, Mueller, Christian, Brunner-La Rocca, Hans-Peter, Tang, W.H. Wilson, Grodin, Justin L., Zhang, Yuhui, Bettencourt, Paulo, Maisel, Alan S., Passino, Claudio, Januzzi, James L., and Emdin, Michele

Published
2017
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18. Comorbidity in lipoprotein apheresis: Their role in the era of new lipid‐lowering therapies.

Author

Sbrana, Francesco, Pianelli, Mascia, Luciani, Roberta, Bigazzi, Federico, Corciulo, Carmen, Ripoli, Andrea, Sampietro, Tiziana, and Dal Pino, Beatrice

Subjects
MEDICAL personnel, BENIGN prostatic hyperplasia, COMORBIDITY, GENERAL practitioners, PEPTIC ulcer
Abstract

Background: Despite advance in pharmacotherapy of lipid disorders, lipoprotein apheresis (LA) plays a leading role in the management of severe hypercholesterolemia and in atherosclerosis prevention. Methods: Aim of this study was to retrospectively evaluate Charlson Comorbidity Index (CCI), presence of major comorbidity, and/or concomitant polypharmacy (definite as 5+ drugs daily) in patients with inherited dyslipidemias on chronic LA. Results: Since 1994, we performed more than 500 LA treatment/year and followed a total of 83 patients (age 56 [47–65] years, male 75%). In subjects with more than 5 years of LA treatment (38 patients, age 54 [45–62] years, male 66%), at the end of the observation time (9 [7–16] years), patients had higher CCI, polypharmacy, anemia, heart failure, peptic ulcer disease, and benign prostatic hyperplasia. Discussion: Even in the era of new lipid‐lowering therapies, the LA treatment established itself as a safe and lifesaving intervention. Patients on chronic LA require a multidisciplinary approach to address their comorbidity and the apheresis unit's medical staff (doctors and nurses) play a pivotal role creating a bridge toward the general practitioner and other specialists for overcoming clinical issues. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Prognostic Value of High-Sensitivity Troponin T in Chronic Heart Failure: An Individual Patient Data Meta-Analysis

Author

Aimo, Alberto, Januzzi, James L., Jr, Vergaro, Giuseppe, Ripoli, Andrea, Latini, Roberto, Masson, Serge, Magnoli, Michela, Anand, Inder S., Cohn, Jay N., Tavazzi, Luigi, Tognoni, Gianni, Gravning, Jørgen, Ueland, Thor, Nymo, Ståle H., Brunner-La Rocca, Hans-Peter, Genis, Antoni Bayes, Lupón, Josep, de Boer, Rudolf A., Yoshihisa, Akiomi, Takeishi, Yasuchika, Egstrup, Michael, Gustafsson, Ida, Gaggin, Hanna K., Eggers, Kai M., Huber, Kurt, Tentzeris, Ioannis, Tang, Wai H.W., Grodin, Justin, Passino, Claudio, and Emdin, Michele

Published
2018
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26. Ischemic strokes in COVID-19: risk factors, obesity paradox, and distinction between trigger and causal association.

Author

Janes, Francesco, Sozio, Emanuela, Gigli, Gian Luigi, Ripoli, Andrea, Sbrana, Francesco, Kuris, Fedra, Nesi, Lorenzo, Semenzin, Tosca, Bertolino, Giacomo, Deana, Cristian, Bagatto, Daniele, Ciardi, Chiara, Fabris, Martina, Merlino, Giovanni, Bax, Francesco, Nilo, Annacarmen, Pez, Sara, Valente, Mariarosaria, and Tascini, Carlo

Subjects
OBESITY paradox, DISEASE risk factors, ISCHEMIC stroke, COVID-19, MYOCARDIAL ischemia, STROKE
Abstract

Background and purpose: Stroke has been described as a COVID-19 complication. However, its occurrence rate, risk factors, and causal relationships are still not well established. Methods: We describe the characteristics of confirmed COVID-19-related strokes among all cases of COVID-19 hospitalized in our health network, from November 1, 2020 to April 30, 2021. Risk factor analysis has been conducted for ischemic stroke (IS), which represents 92% of all confirmed cases of Covid-19-related strokes, and a "causal attribution to infection" classification is provided. Results: In all, 62/4105 hospitalized COVID-19 patients had an acute stroke (1.51%). Severe COVID-19 (OR 2.27--CI 1.06-4.77; p = 0.032), atrial fibrillation (OR 3.65--CI 1.63-7.98; p = 0.001), and ischemic heart disease (OR 4.590--CI 1.714-12.137; p = 0.002) proved to be independent risk factors for IS, while obesity was a protective factor (OR 0.90--CI 0.82-0.97; p = 0.012). COVID-19 had a causal role in 32.1% of IS cases, was a relevant cofactor in 28.6% of cases of IS, and was a possible trigger in 39.3% of events. Conclusion: Our stroke occurrence rate is consistent with other populationbased reports (range 0.34-2.7%). Prespecified peculiar clinical and radiological features allow the distinction between "IS caused by COVID-19" and "IS triggered by COVID-19." Clinical history of vascular diseases and risk factors is crucial in determining the risk of IS in patients with COVID-19. However, the protective effect of a BMI > 30 kg/m2 seems to suggest an obesity paradox. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Safety and Efficacy of a Single Procedure of Extraction and Reimplantation of Infected Cardiovascular Implantable Electronic Device (CIED) in Comparison with Deferral Timing: An Observational Retrospective Multicentric Study.

Author

Tascini, Carlo, Giuliano, Simone, Attanasio, Vittorio, Segreti, Luca, Ripoli, Andrea, Sbrana, Francesco, Severino, Sergio, Sordelli, Chiara, Weisz, Sara Hana, Zanus-Fortes, Agnese, Leanza, Gabriele Maria, Carannante, Novella, Di Cori, Andrea, Bongiorni, Maria Grazia, Zucchelli, Giulio, and De Vivo, Stefano

Subjects
ARTIFICIAL implants, ELECTRONIC equipment, REIMPLANTATION (Surgery), DENTAL extraction, SURVIVAL rate, CARDIOLOGICAL manifestations of general diseases, DEATH rate
Abstract

(1) Background: Infections are among the most frequent and life-threatening complications of cardiovascular implantable electronic device (CIED) implantation. The aim of this study is to compare the outcome and safety of a single-procedure device extraction and contralateral implantation versus the standard-of-care (SoC) two-stage replacement for infected CIEDs. (2) Methods: We retrospectively included 66 patients with CIED infections who were treated at two Italian hospitals. Of the 66 patients enrolled in the study, 27 underwent a single procedure, whereas 39 received SoC treatment. All patients were followed up for 12 months after the procedure. (3) Results: Considering those lost to follow-up, there were no differences in the mortality rates between the two cohorts, with survival rates of 81.5% in the single-procedure group and 84.6% in the SoC group (p = 0.075). (4) Conclusions: Single-procedure reimplantation associated with an active antibiofilm therapy may be a feasible and effective therapeutic option in CIED-dependent and frail patients. Further studies are warranted to define the best treatment regimen and strategies to select patients suitable for the single-procedure reimplantation. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Prognostic value of right ventricular refractory period heterogeneity in Type-1 Brugada electrocardiographic pattern.

Author

Rossi, Andrea, Giannoni, Alberto, Nesti, Martina, Notarstefano, Pasquale, Castiglione, Vincenzo, Solarino, Gianluca, Teresi, Lucio, Mirizzi, Gianluca, Russo, Vincenzo, Panchetti, Luca, Startari, Umberto, Ripoli, Andrea, Gentile, Francesco, Santoro, Amato, Botto, Nicoletta, Casolo, Giancarlo, Sieira, Juan, Pieroni, Maurizio, Santangeli, Pasquale, and Emdin, Michele

Abstract

Aims To investigate the prognostic significance of heterogeneity in the refractoriness of right ventricular (RV) outflow tract (RVOT) and RV apex at the electrophysiological study (EPS) in Brugada syndrome (BrS). Methods and results A cohort of BrS patients (primary prevention) from five Italian centres was retrospectively analysed. Patients with spontaneous or drug-induced Type-1 electrocardiogram (ECG) + symptoms were offered an EPS for prognostic stratification. The primary endpoint was a composite of sudden cardiac death (SCD), resuscitated cardiac arrest, or appropriate intervention by the implantable cardioverter-defibrillator (ICD). Three hundred and seventy-two patients with BrS were evaluated (44 ± 15 years, 69% males, 23% with ICD): 4 SCDs and 17 ICD interventions occurred at follow-up (median 48, interquartile range: 36–60 months). Family history of SCD, syncope, and a spontaneous Type-1 ECG pattern were univariate predictors of the primary endpoint in the whole population. In patients undergoing EPS (n = 198, 53%, 44 ± 12 years, 71% males, 39% with ICD), 3 SCD and 15 ICD interventions occurred at follow-up. In this subset, the primary endpoint was not only predicted by ventricular tachycardia/fibrillation inducibility but also by a difference in the refractory period between RVOT and RV apex (ΔRPRVOT-apex) >60 ms. ΔRPRVOT-apex > 60 ms remained an independent predictor of SCD/ICD shock at bivariate analysis, even when adjusted for the other univariate predictors, showing the highest predictive power at C-statistic analysis (0.75, 95% confidence interval 0.63–0.86). Conclusions Heterogeneity of RV refractory periods is a strong, independent predictor of life-threatening arrhythmias in BrS patients, beyond VT/VF inducibility at EPS and common clinical predictors. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Fully Automated Regional Analysis of Myocardial T2* Values for Iron Quantification Using Deep Learning.

Author

Martini, Nicola, Meloni, Antonella, Positano, Vincenzo, Latta, Daniele Della, Keilberg, Petra, Pistoia, Laura, Spasiano, Anna, Casini, Tommaso, Barone, Angelica, Massa, Antonella, Ripoli, Andrea, and Cademartiri, Filippo

Subjects
ARTIFICIAL neural networks, DEEP learning, IRON overload, CONVOLUTIONAL neural networks, MAGNETIC resonance, INTRACLASS correlation
Abstract

Cardiovascular magnetic resonance (CMR) T2* mapping is the gold standard technique for the assessment of iron overload in the heart. The quantitative analysis of T2* values requires the manual segmentation of T2* images, which is a time-consuming and operator-dependent procedure. This study describes a fully-automated method for the regional analysis of myocardial T2* distribution using a deep convolutional neural network (CNN). A CNN with U-Net architecture was trained to segment multi-echo T2*-weighted images in 16 sectors in accordance with the American Heart Association (AHA) model. We used images from 210 patients (three slices, 10 multi-echo images) with iron overload diseases to train and test the CNN. The performance of the proposed method was quantitatively evaluated on an independent holdout test set by comparing the segmentation accuracy of the CNN and the T2* values obtained by the automated method against ground-truth labels provided by two experts. Segmentation metrics and global and regional T2* values assessed by the proposed DL method closely matched those obtained by experts with excellent intraclass correlation in all myocardial sectors of the AHA model (ICC range [0.944, 0.996]). This method could be effectively adopted in the clinical setting for fast and accurate analysis of myocardial T2*. [ABSTRACT FROM AUTHOR]

Published
2022
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44. Oral administration of gentamicin for prophylaxis of KPC-producing Klebsiella pneumoniae gut colonization in patients treated with a novel parenchymal-sparing liver surgery: the GEN Gut study

Author

Tascini, Carlo, Urbani, Lucio, Sbrana, Francesco, Forfori, Francesco, Licitra, Gabriella, Leoni, Chiara, Balestri, Riccardo, Rossi, Elisabetta, Fortunato, Simona, Leonildi, Alessandro, Puccini, Marco, Di Paolo, Antonello, Ripoli, Andrea, Colombatto, Piero, Menichetti, Francesco, and Buccianti, Piero

Published
2016
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