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363 results on '"Ricci, Davide"'

7. Perovskite‐Like Liquid‐Crystalline Materials Based on Polyfluorinated Imidazolium Cations.

Author

Stergiou, Anastasios, Leccioli, Leonardo, Ricci, Davide, Zaffalon, Matteo L., Brovelli, Sergio, Bombelli, Francesca Baldelli, Terraneo, Giancarlo, Metrangolo, Pierangelo, and Cavallo, Gabriella

Subjects
LIQUID crystal states, SEMICONDUCTORS, LIQUID crystals, PEROVSKITE, MESOPHASES
Abstract

Hybrid Organic‐Inorganic Halide Perovskites (HOIHPs) represent an emerging class of semiconducting materials, widely employed in a variety of optoelectronic applications. Despite their skyrocket growth in the last decade, a detailed understanding on their structure–property relationships is still missing. In this communication, we report two unprecedented perovskite‐like materials based on polyfluorinated imidazolium cations. The two materials show thermotropic liquid crystalline behavior resulting in the emergence of stable mesophases. The manifold intermolecular F ⋅ ⋅ ⋅ F interactions are shown to be meaningful for the stabilization of both the solid‐ and liquid‐crystalline orders of these perovskite‐like materials. Moreover, the structure of the incorporated imidazolium cation was found to tune the properties of the liquid crystalline phase. Collectively, these results may pave the way for the design of a new class of halide perovskite‐based soft materials. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression.

Author

Perriera, Riccardo, Vitale, Emanuele, Pibiri, Ivana, Carollo, Pietro Salvatore, Ricci, Davide, Corrao, Federica, Fiduccia, Ignazio, Melfi, Raffaella, Zizzo, Maria Grazia, Tutone, Marco, Pace, Andrea, and Lentini, Laura

Subjects
STOP codons, GENE expression, DUCHENNE muscular dystrophy, HOUSEKEEPING, NONSENSE mutation
Abstract

Nonsense mutations cause several genetic diseases such as cystic fibrosis, Duchenne muscular dystrophy, β-thalassemia, and Shwachman–Diamond syndrome. These mutations induce the formation of a premature termination codon (PTC) inside the mRNA sequence, resulting in the synthesis of truncated polypeptides. Nonsense suppression therapy mediated by translational readthrough-inducing drugs (TRIDs) is a promising approach to correct these genetic defects. TRIDs generate a ribosome miscoding of the PTC named "translational readthrough" and restore the synthesis of full-length and potentially functional proteins. The new oxadiazole-core TRIDs NV848, NV914, and NV930 (NV) showed translational readthrough activity in nonsense-related in vitro systems. In this work, the possible off-target effect of NV molecules on natural termination codons (NTCs) was investigated. Two different in vitro approaches were used to assess if the NV molecule treatment induces NTC readthrough: (1) a study of the translational-induced p53 molecular weight and functionality; (2) the evaluation of two housekeeping proteins' (Cys-C and β2M) molecular weights. Our results showed that the treatment with NV848, NV914, or NV930 did not induce any translation alterations in both experimental systems. The data suggested that NV molecules have a specific action for the PTCs and an undetectable effect on the NTCs. [ABSTRACT FROM AUTHOR]

Published
2023
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18. Prosthetic valve endocarditis: predictors of early outcome of surgical therapy. A multicentric study

Author

Luciani, Nicola, Mossuto, Eugenio, Ricci, Davide, Luciani, Marco, Russo, Marco, Salsano, Antonio, Pozzoli, Alberto, Pierri, Michele D., D’Onofrio, Augusto, Chiariello, Giovanni A., Glieca, Franco, Canziani, Alberto, Rinaldi, Mauro, Nardi, Paolo, Milazzo, Valentina, Trecarichi, Enrico M., Santini, Francesco, De Bonis, Michele, Torracca, Lucia, Bizzotto, Eleonora, and Tumbarello, Mario

Published
2017
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20. Minimally invasive valve surgery: pushing boundaries over the eighty.

Author

Barbero, Cristina, Brenna, Dario, Salsano, Antonio, Pocar, Marco, Cura Stura, Erik, Calia, Claudia, Sebastiano, Viviana, Rinaldi, Mauro, and Ricci, Davide

Subjects
MITRAL valve surgery, TRICUSPID valve surgery, OCTOGENARIANS, HYPERTENSION, STATISTICS, STATISTICAL significance, CONFIDENCE intervals, MINIMALLY invasive procedures, OPERATIVE surgery, MULTIVARIATE analysis, LOG-rank test, SURGICAL complications, RETROSPECTIVE studies, FISHER exact test, MANN Whitney U Test, SEX distribution, PEARSON correlation (Statistics), T-test (Statistics), QUALITY of life, SURVIVAL analysis (Biometry), DESCRIPTIVE statistics, CHI-squared test, KAPLAN-Meier estimator, LOGISTIC regression analysis, ODDS ratio, DATA analysis software, CREATININE, PROPORTIONAL hazards models, OLD age
Abstract

BACKGROUND Mean age of patients with valves diseases is significantly increasing, and, in the near future, cardiac surgeons will have to deal with a considerable number of patients aged more than 80 years. The remarkable results gained by the minimally invasive approach have encouraged its application in more complex and fragile patients, such as older people. This study aimed to identify the rate of early mortality and major complications, and independent predictors for mid-term mortality in octogenarians undergoing minimally invasive valve surgery. METHODS Octogenarian patients undergoing right mini-thoracotomy mitral and/or tricuspid valve surgery between 2006 and 2020 were included. Primary endpoint was to identify independent predictors for mid-term mortality, and secondary endpoints were operative morality, stroke, independent predictors for early composite outcome, and quality of life at follow-up. RESULTS Analysis was performed on 130 patients. Stroke occurred in one patient (0.8%), while operative mortality was 6% (eight patients). One-year and five-year survival were 86% and 64%, respectively. Logistic regression identified age and creatinine level as independent predictors of mid-term mortality, survival analysis showed that age ≥ 84 years and creatinine level ≥ 1.22 mg/dL were the cut-off points for worst prognosis. Female gender and hypertension were found to be independent predictors of early composite outcome. CONCLUSIONS Results of the present study show that age alone should not be considered a contraindication for minimally invasive valve surgery. Identifying patients who are most likely to have survival and functional benefits after surgery is decisive to achieve optimal health outcomes and prevent futile procedures. [ABSTRACT FROM AUTHOR]

Published
2023
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22. SHARK-NIR: Requirements to the LBT - PSR

Author

VIOTTO, VALENTINA, FARINATO, JACOPO, BERGOMI, Maria, DE PASCALE, Marco, GREGGIO, Davide, MARAFATTO, Luca, RICCI, Davide, and ITA

Abstract

SHARK is an instrument proposed for LBT in the framework of the “2014 Call for Proposals for Instrument Upgrades and New Instruments” (see RD1 and RD2). It is composed by two channels, a visible and a near infrared arm, to be installed one for each LBT telescope, and it will exploit, in its binocular fashion, unique challenging science from exoplanet to extragalactic topics with simultaneous spectral coverage from B to H band, taking advantage of the outstanding performances of the binocular XAO LBT capability.

Published
2022

23. SHARK-NIR: SHARK-NIR Requirements to the LBT - PSR

Author

VIOTTO, VALENTINA, FARINATO, JACOPO, BERGOMI, Maria, DE PASCALE, Marco, GREGGIO, Davide, MARAFATTO, Luca, RICCI, Davide, and ITA

Abstract

SHARK is an instrument proposed for LBT in the framework of the “2014 Call for Proposals for Instrument Upgrades and New Instruments” (see RD1 and RD2). It is composed by two channels, a visible and a near infrared arm, to be installed one for each LBT telescope, and it will exploit, in its binocular fashion, unique challenging science from exoplanet to extragalactic topics with simultaneous spectral coverage from B to H band, taking advantage of the outstanding performances of the binocular XAO LBT capability.

Published
2022

24. SHARK-NIR - Acceptance Test Plan

Author

MARAFATTO, Luca, BERGOMI, Maria, RICCI, Davide, GREGGIO, Davide, RADHAKRISHNAN SANTHAKUMARI, KALYAN KUMAR, and ITA

Abstract

This document has the purpose to identify and describe the SHARK-NIR test plan for the PAE, which will be held at INAF-Osservatorio Astronomico di Padova laboratories.

Published
2022

27. Extracorporeal CO 2 Removal During Renal Replacement Therapy to Allow Lung-Protective Ventilation in Patients With COVID-19–Associated Acute Respiratory Distress Syndrome.

Author

Alessandri, Francesco, Tonetti, Tommaso, Pistidda, Laura, Busani, Stefano, Borrazzo, Cristian, Fanelli, Vito, Polzoni, Mauro, Piazza, Ornella, Lorini, Luca, Cattaneo, Sergio, Ricci, Davide, Zanoni, Andrea, Girardis, Massimo, Terragni, Pierpaolo, Tempesta, Michele, Di Luca, Marina, Pugliese, Francesco, Ranieri, V. Marco, Aldegheri, Giorgio, and Bernd, Claus

Published
2023
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37. Calibration of force actuators on an adaptive secondary prototype

Author

Ricci, Davide, Riccardi, Armando, and Zanotti, Daniela

Subjects
Actuators -- Usage, Optics, Adaptive -- Research, Force and energy -- Research, Calibration -- Methods, Astronomy, Physics
Abstract

In the context of the Large Binocular Telescope project, we present the results of force actuator calibrations performed on an adaptive secondary prototype called P45, a thin deformable glass with magnets glued onto its back. Electromagnetic actuators, controlled in a closed loop with a system of internal metrology based on capacitive sensors, continuously deform its shape to correct the distortions of the wavefront. Calibrations of the force actuators are needed because of the differences between driven forces and measured forces. We describe the calibration procedures and the results, obtained with errors of less than 1.5%. OCIS codes: 220.1080, 350.1260, 350.1270.

Published
2008

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