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1,715,395 results on '"Retrospective Study"'

28. Risk factors of urolithiasis: A hospital-based retrospective study

Author

Thenmozhi Paluchamy, N Dilli Rani, G Bhuvaneswari, and S Tamilselvi

Subjects
renal calculi, retrospective study, risk factors, stone formation, urolithiasis, Medicine
Abstract

AIM: Urolithiasis is the most prevalent urinary tract disease, posing a global public health concern. The escalating prevalence and recurrence rates of urolithiasis are attributed to lifestyle modifications, such as reduced physical activity and dietary habits. This retrospective study aims to explore the risk factors associated with urolithiasis among individuals diagnosed with this condition. Method: A retrospective hospital-based study involving 60 participants meeting the inclusion criteria was conducted. The participants were selected through convenience sampling from the urology, nephrology, and medical wards at Saveetha Medical College and Hospital. Demographic variables were collected, and the risk factors were assessed using a checklist on one-to-one interviews. Results: The study unveiled that most participants (68%) were male. Eighty percent of participants had the risk factor of decreased water intake, 74% consumed excess tomatoes, 56% had a history of recurrent urinary tract infections, 64% consumed an excessive amount of salt daily, 72% experienced a decreased urine output, 53% had a habit of alcohol consumption, and 45% included milk and milk products in their daily diet. A small percentage (5%) had a family history of urolithiasis. Additionally, 6% were undergoing Siddha treatment. Conclusion: The findings from this study underscore the significant factors contributing to urolithiasis. They can inform public health campaigns to raise awareness about lifestyle modifications, dietary changes, and hydration protocols contributing to kidney stone formation.

Published
2024
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29. Nomogram for predicting the risk of nosocomial infections among obstetric inpatients: a large-scale retrospective study in China

Author

Lei Huang, Houzhi Chen, Jielong Wu, Huiping Huang, and Jing Ran

Subjects
Large-scale retrospective study, Obstetric inpatients, Postpartum infections, Risk prediction model, Nomogram, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Objective This study aimed to develop and validate a nomogram for assessing the risk of nosocomial infections among obstetric inpatients, providing a valuable reference for predicting and mitigating the risk of postpartum infections. Methods A retrospective observational study was performed on a cohort of 28,608 obstetric patients admitted for childbirth between 2017 and 2022. Data from the year 2022, comprising 4,153 inpatients, were utilized for model validation. Univariable and multivariable stepwise logistic regression analyses were employed to identify the factors influencing nosocomial infections among obstetric inpatients. A nomogram was subsequently developed based on the final predictive model. The receiver operating characteristic (ROC) curve was utilized to calculate the area under the curve (AUC) to evaluate the predictive accuracy of the nomogram in both the training and validation datasets. Results The gestational weeks > = 37, prenatal anemia, prenatal hypoproteinemia, premature rupture of membranes (PROM), cesarean sction, operative delivery, adverse birth outcomes, length of hospitalization (days) > 5, CVC use and catheterization of ureter were included in the ultimate prediction model. The AUC of the nomogram was 0.828 (0.823, 0.833) in the training dataset and 0.855 (0.844, 0.865) in the validation dataset. Conclusion Through a large-scale retrospective study conducted in China, we developed and independently validated a nomogram to enable personalized postpartum infections risk estimates for obstetric inpatients. Its clinical application can facilitate early identification of high-risk groups, enabling timely infection prevention and control measures.

Published
2024
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30. Effect of Low-Dose Aspirin Use After Thermal Ablation in Patients with Hepatocellular Carcinoma: A Retrospective Study

Author

Chen S, Duan Y, Zhang Y, Cheng L, Cai L, Hou X, Wang X, and Li W

Subjects
thermal ablation, aspirin, hepatocellular carcinoma, survival analysis, retrospective study, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Shanshan Chen,1,2 Youjia Duan,2 Yongchao Zhang,2 Long Cheng,2 Liang Cai,2 Xiaopu Hou,2 Xiaojun Wang,3 Wei Li1,2 1Cancer Center, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Cancer Center, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 3Department of Integrated Traditional Chinese and Western Medicine, Beijing Youan Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Wei Li, Cancer Center, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China, Email weili8989@ccmu.edu.cn Xiaojun Wang, Department of Integrated Traditional Chinese and Western Medicine, Beijing Youan Hospital, Capital Medical University, Beijing, People’s Republic of China, Email w_xiaojun@ccmu.edu.cnPurpose: To determine the effect of aspirin on hepatocellular carcinoma (HCC) recurrence and survival after thermal ablation.Methods: A retrospective analysis was performed to evaluate the efficacy and safety of aspirin in combination with thermal ablation. The clinical data were collected for the enrolled patients. Progression-free survival (PFS), overall survival (OS), and adverse events were analyzed.Results: A total of 174 patients with HCC were enrolled. The median PFS was 11.1 (95% confidence interval [CI]: 8.1− 14.0) months for patients who took aspirin and 8.6 (95% CI: 5.5− 11.8) months for patients who did not take aspirin. The median OS of patients in the aspirin group was 76.7 (95% CI: 58.1− 95.3) months and that in the non-aspirin group was 53.5 (95% CI: 42.7− 64.3) months. In patients with non-viral HCC, OS was significantly better for the aspirin group (P = 0.03) after ablation. The PFS of patients who underwent ablation alone in the aspirin group was obviously superior to that of patients in the non-aspirin group (P = 0.002). Stratified Cox regression analysis demonstrated that aspirin use after ablation might be a protective factor in specific HCC patient subgroups. The incidence of major adverse events did not significantly differ between the two groups.Conclusion: Low-dose aspirin use was associated with better OS in patients with non-viral HCC after thermal ablation. In patients who received thermal ablation alone, the administration of low-dose aspirin could improve PFS. Aspirin use might be a protective factor in some patients after ablation.Keywords: thermal ablation, aspirin, hepatocellular carcinoma, survival analysis, retrospective study

Published
2024

34. Trastuzumab deruxtecan for the treatment of patients with HER2-positive breast cancer with brain and/or leptomeningeal metastases: an updated overall survival analysis using data from a multicenter retrospective study (ROSET-BM)

Author

Nakayama, Takahiro, Niikura, Naoki, Yamanaka, Takashi, Yamamoto, Mitsugu, Matsuura, Kazuo, Inoue, Kenichi, Takahara, Sachiko, Nomura, Hironori, Kita, Shosuke, Yamaguchi, Miki, Aruga, Tomoyuki, Shibata, Nobuhiro, Shimomura, Akihiko, Ozaki, Yuri, Sakai, Shuji, Takiguchi, Daisuke, Takata, Takehiko, Bastanfard, Armin, Shiosakai, Kazuhito, and Tsurutani, Junji

Published
2024
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36. Long-term outcome of invasive pure micropapillary breast cancer compared with invasive mixed micropapillary and invasive ductal breast cancer: a matched retrospective study

Author

Magnoni, Francesca, Bianchi, Beatrice, Pagan, Eleonora, Corso, Giovanni, Sala, Isabella, Bagnardi, Vincenzo, Claudia, Sangalli, Brancaccio, Roberta, Bottazzoli, Elisa, Boato, Antony, Munzone, Elisabetta, Dellapasqua, Silvia, Fusco, Nicola, Viviana, Galimberti, and Veronesi, Paolo

Published
2024
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43. Efficacy of valganciclovir prophylaxis in kidney transplant recipients following low-dose rituximab induction therapy: a multicenter retrospective study

Author

Takehara, Tomohiro, Nishida, Hayato, Ichikawa, Kazunobu, Nawano, Takaaki, Takai, Satoshi, Fukuhara, Hiroki, Matsuura, Tomohiko, Maita, Shinya, Saito, Mitsuru, Murakami, Reiichi, Hatakeyama, Shingo, Obara, Wataru, Saitoh, Hisao, Ohyama, Chikara, Habuchi, Tomonori, Watanabe, Masafumi, and Tsuchiya, Norihiko

Published
2024
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