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706 results on '"Ramin, Susan M"'

1. Cord Blood Haptoglobin, Cerebral Palsy and Death in Infants of Women at Risk for Preterm Birth: A Secondary Analysis of a Randomised Controlled Trial

Author

Buhimschi, Catalin S., Jablonski, Kathleen A., Rouse, Dwight J., Varner, Michael W., Reddy, Uma M., Mercer, Brian M., Leveno, Kenneth J., Wapner, Ronald J., Sorokin, Yoram, Thorp, John M., Jr, Ramin, Susan M., Malone, Fergal D., Carpenter, Marshall W., O'Sullivan, Mary J., Peaceman, Alan M., Saade, George R., Dudley, Donald, Caritis, Steve N., and Buhimschi, Irina A.

Published
2019
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2. Prediction of Cerebral Palsy or Death among Preterm Infants Who Survive the Neonatal Period.

Author

Peaceman, Alan M., Mele, Lisa, Rouse, Dwight J., Leveno, Kenneth J., Mercer, Brian M., Varner, Michael W., Reddy, Uma M., Wapner, Ronald J., Sorokin, Yoram, Thorp, John M., Ramin, Susan M., Malone, Fergal D., O'Sullivan, Mary J., Dudley, Donald J., and Caritis, Steve N.

Subjects
CEREBRAL palsy prevention, RISK assessment, DEATH, SECONDARY analysis, MAGNESIUM sulfate, PREDICTION models, DELIVERY (Obstetrics), RECEIVER operating characteristic curves, RESEARCH funding, SEX distribution, QUESTIONNAIRES, CEREBRAL palsy, PREGNANCY outcomes, DISCHARGE planning, BRAIN diseases, DISEASES, ODDS ratio, GESTATIONAL age, APGAR score, CONFIDENCE intervals, PREGNANCY complications, CEREBRAL hemorrhage, DISEASE risk factors, DISEASE complications, CHILDREN
Abstract

Objective To assess whether neonatal morbidities evident by the time of hospital discharge are associated with subsequent cerebral palsy (CP) or death. Study Design This is a secondary analysis of data from a multicenter placebo-controlled trial of magnesium sulfate for the prevention of CP. The association between prespecified intermediate neonatal outcomes (n = 11) and demographic and clinical factors (n = 10) evident by the time of discharge among surviving infants (n = 1889) and the primary outcome of death or moderate/severe CP at age 2 (n = 73) was estimated, and a prediction model was created. Results Gestational age in weeks at delivery (odds ratio [OR]: 0.74, 95% confidence interval [CI]: 0.67–0.83), grade III or IV intraventricular hemorrhage (IVH) (OR: 5.3, CI: 2.1–13.1), periventricular leukomalacia (PVL) (OR: 46.4, CI: 20.6–104.6), and male gender (OR: 2.5, CI: 1.4–4.5) were associated with death or moderate/severe CP by age 2. Outcomes not significantly associated with the primary outcome included respiratory distress syndrome, bronchopulmonary dysplasia, seizure, necrotizing enterocolitis, neonatal hypotension, 5-minute Apgar score, sepsis, and retinopathy of prematurity. Using all patients, the receiver operating characteristic curve for the final prediction model had an area under the curve of 0.84 (CI: 0.78–0.89). Using these data, the risk of death or developing CP by age 2 can be calculated for individual surviving infants. Conclusion IVH and PVL were the only neonatal complications evident at discharge that contributed to an individual infant's risk of the long-term outcomes of death or CP by age 2. A model that includes these morbidities, gestational age at delivery, and gender is predictive of subsequent neurologic sequelae. Key Points Factors known at hospital discharge are identified which are independently associated with death or CP by age 2. A model was created and validated using these findings to counsel parents. The risk of death or CP can be calculated at the time of hospital discharge. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Fetal Tachycardia in the Setting of Maternal Intrapartum Fever and Perinatal Morbidity.

Author

Tita, Alan T. N., McGee, Paula L., Reddy, Uma M., Bloom, Steven L., Varner, Michael W., Ramin, Susan M., Caritis, Steve N., Peaceman, Alan M., Sorokin, Yoram, Sciscione, Anthony, Carpenter, Marshall W., Mercer, Brian M., Thorp, John M., Malone, Fergal D., and Buhimschi, Catalin

Subjects
RESEARCH, FETAL heart rate, FEVER, CARDIOVASCULAR diseases in pregnancy, DISEASES, PREGNANT women, FETAL diseases, RISK assessment, COMPARATIVE studies, TACHYCARDIA, DESCRIPTIVE statistics, RESEARCH funding, APGAR score, ODDS ratio, PERINATAL period, INTRAPARTUM care, SECONDARY analysis, TRACHEA intubation, DISEASE risk factors
Abstract

Objective The fetal consequences of intrapartum fetal tachycardia with maternal fever or clinical chorioamnionitis are not well studied. We evaluated the association between perinatal morbidity and fetal tachycardia in the setting of intrapartum fever. Study Design Secondary analysis of a multicenter randomized control trial that enrolled 5,341 healthy laboring nulliparous women ≥36 weeks' gestation. Women with intrapartum fever ≥ 38.0°C (including those meeting criteria for clinical chorioamnionitis) after randomization were included in this analysis. Isolated fetal tachycardia was defined as fetal heart rate (FHR) ≥160 beats per minute for at least 10 minutes in the absence of other FHR abnormalities. FHR abnormalities other than tachycardia were excluded from the analysis. The primary outcome was a perinatal composite (5-minute Apgar's score ≤3, intubation, chest compressions, or mortality). Secondary outcomes included low arterial cord pH (pH < 7.20), base deficit ≥12, and cesarean delivery. Results A total of 986 (18.5%) of women in the trial developed intrapartum fever, and 728 (13.7%) met criteria to be analyzed; of these, 728 women 336 (46.2%) had maternal-fetal medicine (MFM) reviewer-defined fetal tachycardia, and 349 of the 550 (63.5%) women during the final hour of labor had validated software (PeriCALM) defined fetal tachycardia. After adjusting for confounders, isolated fetal tachycardia was not associated with a significant difference in the composite perinatal outcome (adjusted odds ratio [aOR] = 3.15 [0.82–12.03]) compared with absence of tachycardia. Fetal tachycardia was associated with higher odds of arterial cord pH <7.2, aOR = 1.48 (1.01–2.17) and of infants with a base deficit ≥ 12, aOR = 2.42 (1.02–5.77), but no significant difference in the odds of cesarean delivery, aOR = 1.33 (0.97–1.82). Conclusion Fetal tachycardia in the setting of intrapartum fever or chorioamnionitis is associated with significantly increased fetal acidemia defined as a pH <7.2 and base excess ≥12 but not with a composite perinatal morbidity. Key Points The perinatal outcomes associated with fetal tachycardia in the setting of maternal fever are undefined. Fetal tachycardia was not significantly associated with perinatal morbidity although the sample size was limited. Fetal tachycardia was associated with an arterial cord pH <7.2 and base deficit of 12 or greater. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Antenatal Magnesium and Cerebral Palsy in Preterm Infants

Author

Hauth, John C., Todd, Allison, Hill, Tawanda, Harris, Stacy, Nelson, Kathleen G., Biasini, Fred J., Anderson, Kristine, Jensen, Marla K., Williams, Lori A., Fullmer, Lisa H., Guzman, Anna M., Collin, Marc, VanBuren, George, Milluzzi, Cynthia, Fundzak, Monica, Santori, Cathy, Johnson, Francee, Landon, Mark B., Latimer, Cheryl, Curry, Valerie, Meadows, Sandra, Sciscione, Anthony, DiVito, Michelle, Talucci, Mary, Desai, Shobhana A., Paul, David A., Sibai, Baha M., Ramsey, Risa D., Mabie, William C., Kao, Lu, Cassie, Melanie, Norman, Gwendolyn S., Driscoll, Debra, Steffy, Barbara, Dombrowski, Mitchell P., Meis, Paul J., Swain, Melissa, Klinepeter, Kurt, O'Shea, T. Michael, Steele, Linda, Moise, Kenneth J., Jr., Brody, Seth, Bernhardt, Janice, Dorman, Karen, Gilstrap, Larry C., III, Day, Mary-Clare, Flinn-Gildersleeve, Erin, Ortiz, Felecia, Kerr, Marcia, Pemberton, Victoria, Paley, Lisa, Paley, Charles, Bousleiman, Sabine, Carmona, Vilmarie, Tillinghast, JoAnn, Allard, Donna, Vohr, Betty, Noel, Lucy, McCarten, Kathleen, Miodovnik, Menachem, Elder, Nancy, Girdler, Wendy, Gratton, Teresa L., Moawad, Atef, Lindheimer, Marshall, Jones, Phyllis L., Doyle, Faith, Alfonso, Carmen, Scott, May, Washington, Ramona, Mallett, Gail, Ramos-Brinson, Mercedes, Simon, Paula, Wen, Tony, Goodrum, Linda A., Saade, George R., Olson, Gayle L., Harirah, Hassan M., Martin, Elizabeth, Xenakis, Elly M.-J., Conway, Deborah L., Berkus, Michael, Kamon, Theresa M., Cotroneo, Margaret, Milford, Cheryl A., Sherman, M. Lynne, Dax, Jody S., Fay-Randall, Lisa, Melton, Carla F., Flores, Ester, Thom, Elizabeth, Jones-Binns, Barbara, Cooney, Maureen, Fischer, Molly L., McLaughlin, Sarah, Brunette, Kimberly, Fricks, Elizabeth, Spong, Catherine Y., Tolivaisa, Susan, McNellis, Donald, Catz, Charlotte, Howell, Kimberly, Nelson, Karin B., Roberts, James M., Hirtz, Deborah G., Weiner, Steven J., Bulas, Dorothy, DiPietro, Michael, Seibert, Joanna, Rouse, Dwight J., Mercer, Brian M., Varner, Michael W., Reddy, Uma M., Iams, Jay D., Wapner, Ronald J., Sorokin, Yoram, Thorp, John M., Jr., Ramin, Susan M., Malone, Fergal D., Carpenter, Marshall W., O'Sullivan, Mary J., Peaceman, Alan M., Hankins, Gary D.V., Dudley, Donald, and Caritis, Steve N.

Published
2015
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7. The association among cytochrome P450 3A, progesterone receptor polymorphisms, plasma 17-alpha hydroxyprogesterone caproate concentrations, and spontaneous preterm birth

Author

Bustos, Martha L., Caritis, Steve N., Jablonski, Kathleen A., Reddy, Uma M., Sorokin, Yoram, Manuck, Tracy, Varner, Michael W., Wapner, Ronald J., Iams, Jay D., Carpenter, Marshall W., Peaceman, Alan M., Mercer, Brian M., Sciscione, Anthony, Rouse, Dwight J., and Ramin, Susan M.

Published
2017
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9. In Reply

Author

Ramin, Susan M., Turrentine, Mark A., and Zahn, Christopher M.

Published
2018
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11. Managing psychiatric illness during pregnancy and breastfeeding: tools for decision making

Author

Puryear, Lucy J., Hall, Nicole R., Monga, Manju, and Ramin, Susan M.

Subjects
United States. Food and Drug Administration, Mentally ill persons, Antidepressants, Mental health, Decision making, Activities of daily living, Pregnancy, Pregnant women, Breast feeding, Health
Abstract

Changing drug safety ratings and conflicting information can make maintaining the mental health of the mother and the well-being of the fetus and infant complex. Here, a pharmacologic framework that [...]

Published
2017

12. Corrigendum to ‘Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length’ Am J Obstet Gynecol 2009;201/4:375-377.e1-8

Author

Owen, John, Hankins, Gary, Iams, Jay D., Berghella, Vincenzo, Sheffield, Jeanne S., Perez-Delboy, Annette, Egerman, Robert S., Wing, Deborah A., Tomlinson, Mark, Silver, Richard, Ramin, Susan M., Guzman, Edwin R., Gordon, Michael, How, Helen Y., Knudtson, Eric J., Szychowski, Jeff M., Cliver, Suzanne, and Hauth, John C.

Published
2024
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18. Timing of treatment initiation for mild gestational diabetes mellitus and perinatal outcomes

Author

Palatnik, Anna, Mele, Lisa, Landon, Mark B., Reddy, Uma M., Ramin, Susan M., Carpenter, Marshall W., Wapner, Ronald J., Varner, Michael W., Rouse, Dwight J., Thorp, John M., Jr., Sciscione, Anthony, Catalano, Patrick, Saade, George R., Caritis, Steve N., Sorokin, Yoram, Peaceman, A., Simon, P., Mallett, G., Casey, B., Leveno, K., Moseley, L., Gold, J., Bradford, D., Fay, L., Garcia, M., Capellan, F., Miodovnik, M., Malone, F., Bousleiman, S., Husami, H., Carmona, V., Fredericks, N., Gantioqui, E., Greenspan, B., Williams, M., Anderson, K., Ashby, P., McAllister, S., Quinn, S., Castinella, F., Guzman, A., Steiner, J., Parker, J., Sheppard, J., Tisdale, J., Northen, A., Andrews, W., Catlow, D., Allard, D., Seebeck, M., Tillinghast, J., Iams, J., Johnson, F., Latimer, C., Weinandy, E., Maselli, B., Dorman, K., Brody, S., Timlin, S., Bernhardt, J., Hoffman, M., Guzman, E., Talucci, M., Grossman, T., Perez, C., Zeghibe, L., Tabangin, P., Mercer, B., Stetzer, B., Milluzzi, C., Dalton, W., Pichette, S., Harper, M., Swain, M., Meis, P., White, J., Gilstrap, L., Cannon, K., Martinez, J., Dusek, D., Moss, J., Brandon, J., Jackson, A., Hankins, G., Sharp, D., Bickus, M., Birkland, H., Cotroneo, M., Cuddy, N., Norman, G., Lockhart, P., Blackwell, S., Quast, L., Tolosa, J., Davis, L., Lairson, E., Cromett, C., Naze, C., Blaser, M., Thom, E., Zachary, J., Getachew, B., Cobb, C., Leuchtenburg, L., Gilbert, S., Spangler, T., Spong, C., Tolivaisa, S., Howell, K., and Anderson, G. D.

Published
2015
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20. The association among cytochrome P450 3A, progesterone receptor polymorphisms, plasma 17-alpha hydroxyprogesterone caproate concentrations, and spontaneous preterm birth

Author

Luce, M., Cotroneo, M., Venkataramanan, R., Zhao, W., Harper, M., Meis, P., Swain, M., Scott, B., Leftwich, C., Norman, G., Driscoll, D., Sudz, C., Wynn, L., Blackwell, S., Thorp, J., Dorman, K., Prata, E., Hamden, K., Anderson, K., Bonnemort, S., Lund, D., Russell, J., Parsons, J., Bousleiman, S., South, S., Carmona, V., Husami, H., Lankford, C., Perez, C., Johnson, F., Landon, M., Cline, D., Walker, H., Allard, D., Tillinghast, J., Dinsmoor, M., Simon, P.J., Huntley, M., Whitaker-Carr, C., Ramos-Brinson, M., Mallett, G., Milluzzi, C., Hunter, J., Dalton, W., Ehrenberg, H., Stetzer, B., Hoffman, M., Talucci, M., Tocci, C., Wilson, S., Lake, M., Andrews, W.W., Northen, A., Parks, M., Files, P. Blake, Gilstrap, L.C., Glenn-Cole, B., Cannon, K., Thom, E., Zachary, J., Palugod, R., Leuchtenburg, L., Spong, C., Klebanoff, M., Tolivaisa, S., Anderson, G., Bustos, Martha L., Caritis, Steve N., Jablonski, Kathleen A., Reddy, Uma M., Sorokin, Yoram, Manuck, Tracy, Varner, Michael W., Wapner, Ronald J., Iams, Jay D., Carpenter, Marshall W., Peaceman, Alan M., Mercer, Brian M., Sciscione, Anthony, Rouse, Dwight J., and Ramin, Susan M.

Published
2017
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34. Advanced lipoprotein measures and recurrent preterm birth

Author

Thorp, John M., Jr., Rice, Madeline Murguia, Harper, Margaret, Klebanoff, Mark, Sorokin, Yoram, Varner, Michael W., Wapner, Ronald J., Caritis, Steve N., Iams, Jay D., Peaceman, Alan M., Mercer, Brian M., Sciscione, Anthony, Rouse, Dwight J., Ramin, Susan M., and Anderson, Garland B.

Published
2013
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35. The association of cerebral palsy and death with small-for-gestational-age birthweight in preterm neonates by individualized and population-based percentiles

Author

Grobman, William A., Lai, Yinglei, Rouse, Dwight J., Spong, Catherine Y., Varner, Michael W., Mercer, Brian M., Leveno, Kenneth J., Iams, Jay D., Wapner, Ronald J., Sorokin, Yoram, Thorp, John M., Jr., Ramin, Susan M., Malone, Fergal D., OʼSullivan, Mary J., Hankins, Gary D.V., and Caritis, Steve N.

Published
2013
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38. Maternal BMI, glucose tolerance, and adverse pregnancy outcomes

Author

Stuebe, Alison M., Landon, Mark B., Lai, Yinglei, Spong, Catherine Y., Carpenter, Marshall W., Ramin, Susan M., Casey, Brian, Wapner, Ronald J., Varner, Michael W., Rouse, Dwight J., Sciscione, Anthony, Catalano, Patrick, Harper, Margaret, Saade, George, Sorokin, Yoram, Peaceman, Alan M., and Tolosa, Jorge E.

Published
2012
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47. Maternal insulin resistance and preeclampsia

Author

Hauth, John C., Clifton, Rebecca G., Roberts, James M., Myatt, Leslie, Spong, Catherine Y., Leveno, Kenneth J., Varner, Michael W., Wapner, Ronald J., Thorp, John M., Jr, Mercer, Brian M., Peaceman, Alan M., Ramin, Susan M., Carpenter, Marshall W., Samuels, Philip, Sciscione, Anthony, Tolosa, Jorge E., Saade, George, Sorokin, Yoram, and Anderson, Garland D.

Published
2011

49. Vitamins C and E to prevent complications of pregnancy-associated hypertension

Author

Roberts, James M., Myatt, Leslie, Spong, Catherine Y., Thom, Elizabeth A., Hauth, John C., Leveno, Kenneth J., Pearson, Gail D., Wapner, Ronald J., Varner, Michael W., Thorp, John M. Jr., Mercer, Brian M., Peaceman, Alan M., Ramin, Susan M., Carpenter, Marshall W., Samuels, Philip, Sciscione, Anthony, Harper, Margaret, Smith, Wendy J., Saade, George, Sorokin, Yoram, and Anderson, Garland B.

Subjects
Hypertension in pregnancy -- Diet therapy, Vitamin C -- Health aspects, Vitamin E -- Health aspects, Drugs -- Adverse and side effects, Drugs -- Prevention
Abstract

A study was conducted to evaluate the benefits of antioxidation supplementation with vitamins C and E in helping prevent adverse events during pregnancy due to hypertension. Results indicated that the intake of the vitamins did not reduce the incidence of complications during pregnancy.

Published
2010

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