1. The Functional Anatomy of Non-Verbal (Pitch Memory) Function in Left and Right Anterior Temporal Lobectomy Patients
- Author
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Joseph I. Tracy, Sonal U Mayekar, R. Nick Hernandez, Brian F. Corbett, Ashwini Sharan, Michael R. Sperling, Mark B. Pascua, and Karol Osipowicz
- Subjects
Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Audiology ,Klüver–Bucy syndrome ,behavioral disciplines and activities ,Article ,Functional Laterality ,Temporal lobe ,Pitch Discrimination ,Judgment ,Text mining ,immune system diseases ,Memory ,hemic and lymphatic diseases ,medicine ,Image Processing, Computer-Assisted ,Humans ,Association (psychology) ,Anterior temporal lobectomy ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Cognition ,Recognition, Psychology ,General Medicine ,Middle Aged ,medicine.disease ,Anterior Temporal Lobectomy ,Magnetic Resonance Imaging ,Temporal Lobe ,Acoustic Stimulation ,Epilepsy, Temporal Lobe ,Data Interpretation, Statistical ,Educational Status ,Kluver-Bucy Syndrome ,Surgery ,Female ,Neurology (clinical) ,business ,psychological phenomena and processes ,Psychomotor Performance - Abstract
An fMRI pitch memory task was administered to left and right anterior temporal lobectomy (ATL) patients. The goal was to verify the neuroanatomical correlates of non-verbal memory, and to determine if pitch memory tasks can identify cognitive risk prior to ATL. The data showed that the bilateral posterior superior temporal lobes implement pitch memory in both ATL patients and NCs (normal controls), indicating that the task can be accomplished with either anterior temporal lobe resected. NCs activate the posterior temporal lobes more strongly than ATL patients during highly accurate performance. In contrast, both ATL groups activate the anterior cingulate in association with accuracy. While our data clarifies the functional neuroanatomy of pitch memory, it also indicates that such tasks do not serve well to lateralize and functionally map potentially “at risk” non-verbal memory skills prior to ATL.
- Published
- 2012