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2. Selective serotonin re-uptake inhibitors affect craniofacial structures in a mouse model.

Author

Quinn N Saluan, George R Bauer, Heema Vyas, Amr Mohi, Emily L Durham, and James J Cray

Subjects
Medicine, Science
Abstract

Selective serotonin re-uptake inhibitors (SSRI) widely used in the treatment of depression, anxiety, obsessive compulsive disorder, fibromyalgia, and migraine are among the most heavily prescribed drug class in the United States (US). Along with an overall rise in SSRI use, these medications are increasingly used by pregnant individuals and recent preclinical and clinical studies have indicated that SSRIs may increase the prevalence of congenital abnormalities and birth defects of the craniofacial region. Our group has developed pre-clinical models of study, including those that mimic the clinical use of SSRI in mice. Here we designed a study to interrogate a commonly prescribed SSRI drug, Citalopram, for its effects on craniofacial and dental development when introduced in utero. Pre-natal exposure to a clinically relevant dose of citalopram resulted in changes in craniofacial form identified by an increase in endocast volume in SSRI exposed postnatal day 15 mouse pups. More specifically, cranial length and synchondrosis length increased in SSRI exposed pups as compared to control pups of the same age. Additionally, growth center (synchondrosis) height and width and palate length and width decreased in SSRI exposed pups as compared to control un-exposed pups. Effects of SSRI on the molars was minimal. Craniofacial growth and development continue to be an area of interest in the investigation of in utero pharmaceutical drug exposure. Altogether these data indicate that prenatal SSRI exposure affects craniofacial form in multiple tissues and specifically at growth sites and centers of the skull.

Published
2024
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4. Practical Issues in Estimating Classification Accuracy and Consistency with R Package cacIRT

Author

Lathrop, Quinn N.

Abstract

There are two main lines of research in estimating classification accuracy (CA) and classification consistency (CC) under Item Response Theory (IRT). The R package cacIRT provides computer implementations of both approaches in an accessible and unified framework. Even with available implementations, there remains decisions a researcher faces when choosing and applying the best approach for the situation. This paper identifies and discusses the practical issues that researchers may face when estimating CA and CC. To exemplify the analytic decisions, both approaches are applied to a common dataset with discussion. In addition to generalizable guidance, the demonstration provides R code for the cacIRT package.

Published
2015

5. A seismic assessment procedure for historic structures

Author

Quinn, N. L.

Subjects
624.1
Abstract

The majority of the world's population live in "vernacular" buildings, often dismissed as unengineered structures, built in distinct local styles using local materials and structural techniques. The collapse of these buildings has been blamed for a large number of deaths in recent earthquakes, leading to appeals for their demolition or strengthening. However, many are of high historical and cultural significance. Furthermore, their seismic behaviour is often poorly understood, and well-intentioned interventions may adversely affect their performance unless properly verified by a robust seismic assessment. Current evaluation procedures are not appropriate for these buildings as they do not emphasise compliance with conservation principles, nor consider unique structural techniques and materials. This thesis aims to develop a novel decision-tree-based diagnostic approach for the seismic assessment of historic vernacular buildings. The diagnosis is performed in two stages; a preliminary diagnosis based on onsite observations and archival research, and a detailed, more quantitative diagnosis based on numerical analysis and experimental testing. At each stage, four parameters are assessed; the initial structural concept, the interaction between components, the quality of connections, and the quality of the structural fabric. The procedure aims to be applicable to any class of vernacular buildings with minimal modifications. The approach has been validated by application to two historic residential buildings in Peru with different structural systems. To arrive at a diagnosis, experimental tests have been performed, and detailed finite element models developed at global and local level, which are shown to adequately represent the lateral response of the system. A specific focus is made on the characterisation of quincha, a technique consisting of a timber frame infilled with a weave of canes and mud. The procedure is applicable to both building types, with only minor modifications, and has proven to be a valuable tool for identifying vulnerabilities of the building.

Published
2017

7. Effects of microclimate on disease prevalence across an urbanization gradient.

Author

Fox, Quinn N., Farah, Keiko N., Shaw, Olivia S., Pollowitz, Michelle, Sánchez‐Conde, Armando, Goodson, Carrie, and Penczykowski, Rachel M.

Subjects
*DISEASE prevalence, *URBAN heat islands, *POWDERY mildew diseases, *CITY dwellers, *URBANIZATION, *NEIGHBORHOODS, *CLIMATE change
Abstract

Increased temperatures associated with urbanization (the "urban heat island" effect) have been shown to impact a wide range of traits across diverse taxa. At the same time, climatic conditions vary at fine spatial scales within habitats due to factors including shade from shrubs, trees, and built structures. Patches of shade may function as microclimate refugia that allow species to occur in habitats where high temperatures and/or exposure to ultraviolet radiation would otherwise be prohibitive. However, the importance of shaded microhabitats for interactions between species across urbanized landscapes remains poorly understood. Weedy plants and their foliar pathogens are a tractable system for studying how multiple scales of climatic variation influence infection prevalence. Powdery mildew pathogens are particularly well suited to this work, as these fungi can be visibly diagnosed on leaf surfaces. We studied the effects of shaded microclimates on rates of powdery mildew infection on Plantago host species in (1) "pandemic pivot" surveys in which undergraduate students recorded shade and infection status of thousands of plants along road verges in urban and suburban residential neighborhoods, (2) monthly surveys of plant populations in 22 parks along an urbanization gradient, and (3) a manipulative field experiment directly testing the effects of shade on the growth and transmission of powdery mildew. Together, our field survey results show strong positive effects of shade on mildew infection in wild Plantago populations across urban, suburban, and rural habitats. Our experiment suggests that this relationship is causal, where microclimate conditions associated with shade promote pathogen growth. Overall, infection prevalence increased with urbanization despite a negative association between urbanization and tree cover at the landscape scale. These findings highlight the importance of taking microclimate heterogeneity into account when establishing links between macroclimate or land use context and prevalence of disease. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Coronal Heating as Determined by the Solar Flare Frequency Distribution Obtained by Aggregating Case Studies

Author

James Paul Mason, Alexandra Werth, Colin G. West, Allison Youngblood, Donald L. Woodraska, Courtney L. Peck, Arvind J. Aradhya, Yijian Cai, David Chaparro, James W. Erikson, Koushik Ganesan, T. R. Geerdts, Thi D Hoang, Thomas M. Horning, Yan Jin, Haixin Liu, Noah Lordi, Zheng Luo, Thanmay S. Menon, Josephine C. Meyer, Emma E Nelson, Kristin A. Oliver, Jorge L Ramirez Ortiz, Andrew Osborne, Alyx Patterson, Nick Pellatz, John Pitten, Nanako Shitara, Daniel Steckhahn, Aseem Visal, Hongda Wang, Chaoran Wang, Evan Wickenden, John Wilson, Mengyu Wu, Nikolay Yegovtsev, Ingrid H Zimmermann, James Holland Aaron, Jumana T. Abdullah, Jonathan M. Abrams, Riley Abrashoff, Andres B. Acevedo, Iker Acha, Daniela M. Meza Acosta, Megan M. Adam, Dante Q. Adams, Kalvyn N Adams, Elena R Adams, Zainab A. Akbar, Ushmi H. Akruwala, Adel Al-Ghazwi, Batool H. Alabbas, Areej A. Alawadhi, Yazeed A. Alharbi, Mohammed S. Alahmed, Mohammed A. Albakr, Yusef J. Albalushi, Jonathan Albaum, Ahmed Aldhamen, Nolan Ales, Mohammad Alesmail, Abdulelah Alhabeeb, Dania Alhamli, Isehaq Alhuseini, Suhail Alkaabi, Tameem Alkhezzi, Mohamed Alkubaisi, Nasser Allanqawi, Martin Allsbrook, Yousef A. Almohsen, Justin Thomas Almquist, Teeb Alnaji, Yousef A Alnasrallah, Nicholas Alonzi, Meshal Alosaimi, Emeen Alqabani, Mohammad Alrubaie, Reema A. Alsinan, Ava L. Altenbern, Abdullah Altokhais, Saleh A. Alyami, Federico Ameijenda, Hamzi Amer, Meggan Amos, Hunter J. Anderson, Carter Andrew, Jesse C Andringa, Abigail Angwin, Gabreece Van Anne, Andrew Aramians, Camila Villamil Arango, Jack. W. Archibald, Brian A. Arias-Robles, Maryam Aryan, Kevin Ash, Justin Astalos, N. S. Atchley-Rivers, Dakota N. Augenstein, Bryce W. Austin, Abhinav Avula, Matthew C. Aycock, Abdulrahman A. Baflah, Sahana Balaji, Brian Balajonda, Leo M Balcer, James O. Baldwin, David J Banda, Titus Bard, Abby Barmore, Grant M. Barnes, Logan D. W. Barnhart, Kevin M. Barone, Jessica L. Bartman, Claire Bassel, Catalina S Bastias, Batchimeg Bat-Ulzii, Jasleen Batra, Lexi Battist, Joshua Bay, Simone Beach, Sara Beard, Quinn I Beato, Ryan Beattie, Thomas Beatty, Tristan De La Beaujardiere, Jacob N. Beauprez, M. G. Beck, Lily Beck, Simone E. Becker, Braden Behr, Timothy A. Behrer, Joshua Beijer, Brennan J. Belei, Annelene L. Belknap, Aislyn Bell, Caden Bence, Evan Benke, Naomi Berhanu, Zachary D. Berriman-Rozen, Chrisanna Bertuccio, Owen A. Berv, Blaine B. Biediger, Samuel J Biehle, Brennen Billig, Jacob Billingsley, Jayce A. Billman, Connor J. Biron, Gabrielle E. Bisacca, Cassidy A. Blake, Guillermo Blandon, Olivia Blevins, Ethan Blouin, Michal Bodzianowski, Taylor A. Boeyink, Matthew Bondar, Lauren Bone, Alberto Espinosa De Los Monteros Bonilla, William T Borelli, Luke R. Borgerding, Troy Bowen, Christine Boyer, Aidan Boyer, Aidan P. Boyle, Tom Boyne, Donovan Branch, Ariana E. Brecl, David J. Brennan, Alexander J Brimhall, Jennifer L. Brockman, Sarah Brookins, Gabriel T. Brown, Cameron L. Brown, Ryan Brown, Jordi Brownlow, Grant Brumage-Heller, Preston J. Brumley, Samuel Bryan, A. Brzostowicz, Maryam Buhamad, Gigi Bullard-Connor, J. R. Ramirez Bunsow, Annemarie C. Burns, John J. Burritt, Nicholas David Burton, Taylor Burton, Celeste Busch, Dylan R. Butler, B. W. Buxton, Malena C. Toups, Carter C. Cabbage, Breonna Cage, Jackson R. Cahn, Andrew J Campbell, Braden P. Canales, Alejandro R. Cancio, Luke Carey, Emma L. Carillion, Michael Andrew Carpender, Emily Carpenter, Shivank Chadda, Paige Chambers, Jasey Chanders, Olivia M. Chandler, Ethan C. Chang, Mitchell G. Chapman, Logan T. Chapman, S. Chavali, Luis Chavez, Kevin Chen, Lily Chen, Sam Chen, Judy Chen, Jenisha Chhetri, Bradyn Chiles, Kayla M. Chizmar, Katherine E Christiansen, Nicholas A. Cisne, Alexis Cisneros, David B. Clark, Evelyn Clarke, Peter C Clarkson, Alexis R. Clausi, Brooke Cochran, Ryan W. Coe, Aislinn Coleman-Plante, Jake R. Colleran, Zachary Colleran, Curran Collier, Nathaniel A. Collins, Sarah Collins, Jack C. Collins, Michael Colozzi, Aurora Colter, Rebecca A. Cone, Thomas C. Conroy, Reese Conti, Charles J. Contizano, Destiny J. Cool, Nicholas M. Cooper, Jessica S Corbitt, Jonas Courtney, Olivia Courtney, Corben L. Cox, Wilmsen B. Craig, Joshua B. Creany, Anastasia Crews, K. A. Crocker, A. J. Croteau, Christian J. Crow, Zoe Cruse, Avril Cruz, Tyler L. Curnow, Hayden Current, Riley T. Curry, Libby Cutler, Aidan St. Cyr, Frederick M. Dabberdt, Johnston Daboub, Olivia Damgaard, Swagatam Das, Emma A. B. Davis, Elyse Debarros, Sean Deel, Megan E. Delasantos, Tianyue Deng, Zachary Derwin, Om Desai, Kai Dewey, John S. Dias, Kenzie A. Dice, R. Dick, Cyrus A. Dicken, Henry Dietrick, Alexis M. Dinser, Alyssa M. Dixon, Thomas J. Dixon, Helen C. Do, Chris H Doan, Connor Doane, Joshua Dodrill, Timothy Doermer, Lizbeth Montoya Dominguez, J. Dominguez, Emerson N. Domke, Caroline R. Doran, Jackson A. Dorr, Philip Dorricott, Danielle C. Dresdner, Michael Driscoll, Kailer H. Driscoll, Sheridan J. Duncan, Christian Dunlap, Gabrielle M. Dunn, Tien Q. Duong, Tomi Oshima Dupeyron, Peter Dvorak, Andrew East, Andrew N. East, Bree Edwards, Lauren Ehrlich, Sara I. Elbashir, Rasce Engelhardt, Jacob Engelstad, Colin England, Andrew Enrich, Abbey Erickson, Benjamin Erickson, Nathan Evans, Calvin A Ewing, Elizabeth A. Eyeson, Ian Faber, Avery M. Fails, John T Fauntleroy, Kevin Fell, Zitian Feng, Logan D. Fenwick, Nikita Feoktistov, Ryann Fife, John Alfred D. Figueirinhas, Jean-Paul Fisch, Emmalee Fischer, Jules Fischer-White, Aidan F. Fitton, Alexander Fix, Lydia Flackett, Fernando Flores, Aidan Floyd, Leonardo Del Foco, Adeduni Folarin, Aidan E. Forbes, Elise Fortino, Benjamin L. Fougere, Alexandra A. Fowler, Margaret Fox, James M. French, Katherine V. French, Florian G. Frick, Calvin R. Fuchs, Bethany E. S. Fuhrman, Sebastian Furney, Moutamen Gabir, Gabriela Galarraga, Skylar Gale, Keala C. Gapin, A. J. Garscadden, Rachel Gasser, Lily Gayou, Emily E. Gearhart, Jane Geisman, Julianne R. Geneser, Sl Genne, Julia G Gentile, Eleanor Gentry, Jacob D. George, Nathaniel James Georgiades, Phillip Gerhardstein, Clint Gersabeck, Bandar Abu Ghaith, Dorsa Ghiassi, B. C. Giebner, Dalton Gilmartin, Connor B. Gilpatrick, Michael Gjini, Olivia Golden, Nathan T. Golding, C. A. Goldsberry, Angel R. Gomez, Angel A. Gomez, Sean Gopalakrishnan, Mariam Gopalani, Nicholas Gotlib, Alaina S. Graham, Michael J Gray, Alannah H. Gregory, Joshua A. Gregory, Kristyn Grell, Justus Griego, Nicholas F. Griffin, Kyle J. Griffin, Matt Guerrero, Nicole Gunderson, Mutian Guo, E. R. Gustavsson, Grace K. Hach, L. N. Haile, Jessica Haines, Jack J. Mc Hale, Ryder Buchanan Hales, Mark S. Haley, Jacqueline L. Hall, Sean R. Hamilton, Soonhee Han, Tyler Hand, Luke C. Hanley, Connor M Hansen, Joshua A. Hansen, Jonathan Hansson, Tony Yunfei Hao, Nicholas Haratsaris, Isabelle Hardie, Dillon F. Hardwick, Cameron T. Hares, Logan Swous Harris, Coyle M. Harris, Omer Hart, Kyle Hashiro, Elsie Hattendorf, Calder Haubrich, Elijah Hawat, Griffin A. Hayrynen, Danielle A. Heintz, Tim Hellweg, Angel Hernandez, Emanuel Herrera, Robert N. Herrington, Tim Herwig, Troy M. Hesse, Quinn Hiatt, Lea Pearl Hibbard, Imari R. Hicks, Andrew J. Hicks, Nigel Highhouse, Annalise K. Hildebrand, Paula Hill, Hallie Hill, Evan Hintsa, Anna E. Hirschmann, Travis Hitt, Ella Ho, Isabelle J. Hoff, Alex Hoffman, Blake A. Hogen, Linda Horne, Timothy J Houck, Noah H. Howell, E. M. Hrudka, J. Hu, Jianyang Huang, Chenqi Huang, Shancheng Huang, Zachary A. Hudson, Nathan C. Hudson, Tyler J. Huebsch, Owen Hull, Samuel C Hunter, Troy Husted, Abigail P. Hutabarat, Leslie Huynh, Antonio E. Samour Ii, Yolande Idoine, Julia A. Ingram, Taro Iovan, Samuel A. Isert, Antonio Salcido-Alcontar, Thomas Jacobsen, Alan A Jaimes, Connor Jameson, J. R. Jarriel, Sam Jarvis, Josh Jenkins, Alexander V. Jensen, Jacob Jeong, Luke A. Jeseritz, Trevor Jesse, Soo Yeun Ji, Yufan Jiang, Owen Johnson, Matthew Johnson, Sawyer Johnson, Julia Johnston, Braedon Y. Johnston, Olivia M. Jones, M. R. Jones, Tara Jourabchi, Tony A. House, Parker Juels, Sabrina J. H. T. Kainz, Emily Kaiser, Nicolas Ian Kallemeyn, Madison H. Kalmus, Etash Kalra, Margaret Kamenetskiy, Jeerakit Kanokthippayakun, Shaun D. Kapla, Brennan J. Karsh, Caden J. Keating, Morgan A. Kelley, Michael P. Kelley, Nicholas Kelly, James Kelly, Teagan Kelly, Christopher M Kelly, Kellen Kennedy, Cayla J. Kennedy, Forrest Kennedy, Abigail Kennedy, Liana Kerr-Layton, Marilyn Ketterer, Ibraheem A. Khan, Usman Khan, Sapriya Khanal, Jack L. Kiechlin, Dominic Killian, Kevin Kim, Brian T. Kim, Matthew M. Kim, Jake Kim, Aspen Kimlicko, Isabel M Kipp, Hunter B. Kirkpatrick, Natalie Kissner, Emily R. Kite, Olivia R. Kleinhaus, Philip Whiting Knott, Will Koch, Greta Koenig, Emily Koke, Thomas Kokes, Yash S. Kothamdi, Zack Krajnak, Zoe M. Kresek, Dylan Kriegman, Jake E. Kritzberg, Davis J. Krueger, Bartlomiej Kubiak, Kirsten Kuehl, Chrisanne Kuester, Nicolas A. Kuiper, Aman Priyadarshi Kumar, Connor Kuybus, Daniel Kwiatkowski, Quintin Y. Lafemina, Kevin Lacjak, Kyle Lahmers, Antonia Lam, Kalin Landrey, Maxwell B. Lantz, Zachary Larter, Benjamin P. Lau, Megan Lauzon, Rian Lawlor, Tyler Learned, E. C. Lee, Junwon Lee, Adrianna J. Lee, Justin Lee, Alexis Ying-Shan Lee, Christian J Lee, Nathaniel F. Lee, Linzhi Leiker, Dylan Lengerich, Cecilia Leoni, Adrienne R. Lezak, David Y. Li, Isaac Li, Ryan Z. Liao, Bridget Linders, Morgan I Linger, Katherine B. Linnane, Sam Lippincott, Barrett Lister, Shelby D Litton, Nianzi Liu, Steven Y. Liu, Timothy W. Logan, Nathan Londres, Mia C. Lonergan, Emily Lookhoff, N. E. Loomis, Christian Lopez, Justin Loring, Jeffrey Lucca, Dax Lukianow, Nathan M. Cheang, William Macdonald, Claire A. Madonna, Kasey O. Madsen, Tiffany E. Maksimuk, Macguire Mallory, Ryan A. Malone, Blake Maly, Xander R. Manzanares, Aimee S. Maravi, Serafima M. Marcus, Nasreen Marikar, Josie A. Marquez, Mathew J. Marquez, Lauren Marsh, Toni Marsh, Logan S. Martin, Alexa M. Martinez, Jose R. Martinez, Hazelia K. Martinez, Cara Martyr, Mirna Masri, Giorgio Matessi, Adam Izz Khan Mohd Reduan Mathavan, Randi M. Mathieson, Kabir P. Mathur, Graham Mauer, Victoria A. Mayer, Liam Mazzotta, Glen S. Mccammon, Rowan Mcconvey, Tyler Mccormick, Andrew Mccoy, Kelleen Mcentee, Meaghan V. Mcgarvey, Riley M. Mcgill, James K. Mcintyre, Finbar K. Mckemey, Zane Mcmorris, Jesse J. Mcmullan, Ella Mcquaid, Caden Mcvey, Kyle Mccurry, Mateo M. Medellin, Melissa Medialdea, Amar Mehidic, Stella Meillon, Jonah B. Meiselman-Ashen, Sarah Mellett, Dominic Menassa, Citlali Mendez, Patricia Mendoza-Anselmi, Riley Menke, Sarah Mesgina, William J. Mewhirter, Ethan Meyer, Aya M. Miften, Ethan J. Miles, Andrew Miller, Joshua B. Miller, Emily B. Millican, Sarah J. Millican, Dylan P. Mills, Josh Minimo, Jay H. Misener, Alexander J. Mitchell, Alexander Z. Mizzi, Luis Molina-Saenz, Tyler S Moll, Hayden Moll, Maximus Montano, Michael Montoya, Eli Monyek, Jacqueline Rodriguez Mora, Gavin Morales, Genaro Morales, Annalise M. Morelock, Cora Morency, Angel J. Moreno, Remy Morgan, Alexander P. Moss, Brandon A. Muckenthaler, Alexander Mueller, Owen T. Mulcahy, Aria T. Mundy, Alexis A. Muniz, Maxwell J. Murphy, Madalyn C. Murphy, Ryan C. Murphy, Tyler Murrel, Andrew J. Musgrave, Michael S. Myer, Kshmya Nandu, Elena R. Napoletano, Abdulaziz Naqi, Anoothi Narayan, Liebe Nasser, Brenna K Neeland, Molly Nehring, Maya Li Nelson, Lena P. Nguyen, Lena Nguyen, Leonardo Nguyen, Valerie A. Nguyen, Khoa D Nguyen, Kelso Norden, Cooper Norris, Dario Nunes-Valdes, Rosemary O. Nussbaum, Cian O’Sullivan, Ian O’Neill, S. H. Oakes, Anand Odbayar, Caleb Ogle, Sean Oishi-Holder, Nicholas Olguin, Nathaniel P. Olson, Jason Ong, Elena N. Opp, Dan Orbidan, Ryan Oros, Althea E. Ort, Matthew Osborn, Austin Osogwin, Grant Otto, Jessica Oudakker, Igor Overchuk, Hannah M. Padgette, Jacqueline Padilla, Mallory Palizzi, Madeleine L. Palmgren, Adler Palos, Luke J. Pan, Nathan L. Parker, Sasha R. Parker, Evan J. Parkinson, Anish Parulekar, Paige J. Pastor, Kajal Patel, Akhil Patel, Neil S. Patel, Samuel Patti, Catherine Patton, Genevieve K. Payne, Matthew P. Payne, Harrison M. Pearl, Charles B. Beck Von Peccoz, Alexander J. Pedersen, Lily M. Pelster, Munisettha E. Peou, J. S. Perez, Freddy Perez, Anneliese Pesce, Audrey J. Petersen, B. Peterson, Romeo S. L. Petric, Joshua Pettine, Ethan J. Phalen, Alexander V. Pham, Denise M. Phan, Callie C Pherigo, Lance Phillips, Justin Phillips, Krista Phommatha, Alex Pietras, Tawanchai P. Pine, Sedique Pitsuean-Meier, Andrew M. Pixley, Will Plantz, William C. Plummer, Kaitlyn E. Plutt, Audrey E. Plzak, Kyle Pohle, Hyden Polikoff, Matthew Pollard, Madelyn Polly, Trevor J. Porter, David Price, Nicholas K. Price, Gale H. Prinster, Henry Austin Propper, Josh Quarderer, Megan S. Quinn, Oliver Quinonez, Devon Quispe, Cameron Ragsdale, Anna L. Rahn, M. Rakhmonova, Anoush K Ralapanawe, Nidhi Ramachandra, Nathaniel Ramirez, Ariana C. Ramirez, Sacha Ramirez, Parker Randolph, Anurag Ranjan, Frederick C Rankin, Sarah Grace Rapaport, Nicholas O Ratajczyk, Mia G. V. Ray, Brian D. Reagan, John C. Recchia, Brooklyn J. Reddy, Joseph Reed, Charlie Reed, Justin Reeves, Eileen N. Reh, Ferin J. Von Reich, Andrea B. Reyna, Alexander Reynolds, Hope Reynolds, Matthew Rippel, Guillermo A. Rivas, Anna Linnea Rives, Amanda M. Robert, Samuel M. Robertson, Maeve Rodgers, Stewart Rojec, Andres C. Romero, Ryan Rosasco, Beth Rossman, Michael Rotter, Tyndall Rounsefell, Charlotte Rouse, Allie C. Routledge, Marc G. Roy, Zoe A. Roy, Ryan Ruger, Kendall Ruggles-Delgado, Ian C. Rule, Madigan Rumley, Brenton M. Runyon, Collin Ruprecht, Bowman Russell, Sloan Russell, Diana Ryder, David Saeb, J. Salazar, Violeta Salazar, Maxwell Saldi, Jose A. Salgado, Adam D. Salindeho, Ethan S. Sanchez, Gustavo Sanchez-Sanchez, Darian Sarfaraz, Sucheta Sarkar, Ginn A. Sato, Carl Savage, Marcus T. Schaller, Benjamin T. Scheck, Jared A. W. Schlenker, Matthew J Schofer, Stephanie H. Schubert, Courtney Schultze, Grace K Schumacher, Kasper Seglem, Lauren Serio, Octave Seux, Hannan Shahba, Callie D. Shannahan, Shajesh Sharma, Nathan Shaver, Timothy Shaw, Arlee K. Shelby, Emma Shelby, Grace Shelchuk, Tucker Sheldrake, Daniel P. Sherry, Kyle Z. Shi, Amanda M. Shields, Kyungeun Shin, Michael C. Shockley, Dominick Shoha, Jadon Shortman, Mitchell Shuttleworth, Lisa Sibrell, Molly G. Sickler, Nathan Siles, H. K. Silvester, Conor Simmons, Dylan M. Simone, Anna Simone, Savi Singh, Maya A. Singh, Madeline Sinkovic, Leo Sipowicz, Chris Sjoroos, Ryan Slocum, Colin Slyne, Korben Smart, Alexandra N. Smith, Kelly Smith, Corey Smith, Elena K. Smith, Samantha M. Smith, Percy Smith, Trevor J Smith, G. L. Snyder, Daniel A. Soby, Arman S. Sohail, William J. Solorio, Lincoln Solt, Caitlin Soon, Ava A Spangler, Benjamin C. Spicer, Ashish Srivastava, Emily Stamos, Peter Starbuck, Ethan K. Stark, Travis Starling, Caitlyn Staudenmier, Sheen L. Steinbarth, Christopher H. Steinsberger, Tyler Stepaniak, Ellie N. Steward, Trey Stewart, T. C. Stewart, Cooper N. Stratmeyer, Grant L. Stratton, Jordin L. Stribling, S. A Sulaiman, Brandon J Sullivan, M. E. Sundell, Sohan N. Sur, Rohan Suri, Jason R. Swartz, Joshua D. Sweeney, Konner Syed, Emi Szabo, Philip Szeremeta, Michael-Tan D. Ta, Nolan C. Tanguma, Kyle Taulman, Nicole Taylor, Eleanor Taylor, Liam C. Taylor, K. E. Tayman, Yesica Tellez, Richard Terrile, Corey D Tesdahl, Quinn N. Thielmann, Gerig Thoman, Daniel Thomas, Jeffrey J. Thomas, William N. Thompson, Noah R. Thornally, Darien P. Tobin, Kelly Ton, Nathaniel J. Toon, Kevin Tran, Bryn Tran, Maedee Trank-Greene, Emily D. Trautwein, Robert B. Traxler, Judah Tressler, Tyson R. Trofino, Thomas Troisi, Benjamin L. Trunko, Joshua K. Truong, Julia Tucker, Thomas D Umbricht, C. H. Uphoff, Zachary T. Upthegrove, Shreenija Vadayar, Whitney Valencia, Mia M. Vallery, Eleanor Vanetten, John D. Vann, Ilian Varela, Alexandr Vassilyev, Nicholas J. Vaver, Anjali A. Velamala, Evan Vendetti, Nancy Ortiz Venegas, Aditya V. Vepa, Marcus T. Vess, Jenna S. Veta, Andrew Victory, Jessica Vinson, Connor Maklain Vogel, Michaela Wagoner, Steven P. Wallace, Logan Wallace, Caroline Waller, Jiawei Wang, Keenan Warble, N. R. D. Ward-Chene, James Adam Watson, Robert J. Weber, Aidan B. Wegner, Anthony A Weigand, Amanda M. Weiner, Ayana West, Ethan Benjamin Wexler, Nicola H. Wheeler, Jamison R. White, Zachary White, Oliver S. White, Lloyd C. Whittall, Isaac Wilcove, Blake C. Wilkinson, John S. Willard, Abigail K. Williams, Sajan Williams, Orion K. Wilson, Evan M. Wilson, Timothy R. Wilson, Connor B. Wilson, Briahn Witkoff, Aubrey M. Wolfe, Jackson R. Wolle, Travis M. Wood, Aiden L. Woodard, Katelynn Wootten, Catherine Xiao, Jianing Yang, Zhanchao Yang, Trenton J. Young, Isabel Young, Thomas Zenner, Jiaqi Zhang, Tianwei Zhao, Tiannie Zhao, Noah Y. Zhao, Chongrui Zhou, Josh J Ziebold, Lucas J. Ziegler, James C. Zygmunt, Jinhua Zhang, and H. J. Lewandowski

Published
2023
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13. The Mediated MIMIC Model for Understanding the Underlying Mechanism of DIF

Author

Cheng, Ying, Shao, Can, and Lathrop, Quinn N.

Abstract

Due to its flexibility, the multiple-indicator, multiple-causes (MIMIC) model has become an increasingly popular method for the detection of differential item functioning (DIF). In this article, we propose the mediated MIMIC model method to uncover the underlying mechanism of DIF. This method extends the usual MIMIC model by including one variable or multiple variables that may completely or partially mediate the DIF effect. If complete mediation effect is found, the DIF effect is fully accounted for. Through our simulation study, we find that the mediated MIMIC model is very successful in detecting the mediation effect that completely or partially accounts for DIF, while keeping the Type I error rate well controlled for both balanced and unbalanced sample sizes between focal and reference groups. Because it is successful in detecting such mediation effects, the mediated MIMIC model may help explain DIF and give guidance in the revision of a DIF item.

Published
2016
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14. Preliminary estimates of the contribution of Arctic nitrogen fixation to the global nitrogen budget

Author

Rachel E. Sipler, Donglai Gong, Steven E. Baer, Marta P. Sanderson, Quinn N. Roberts, Margaret R. Mulholland, and Deborah A. Bronk

Subjects
Oceanography, GC1-1581
Abstract

Abstract Dinitrogen (N2) fixation is the source of all biologically available nitrogen on earth, and its presence or absence impacts net primary production and global biogeochemical cycles. Here, we report rates of 3.5–17.2 nmol N L−1 d−1 in the ice‐free coastal Alaskan Arctic to show that N2 fixation in the Arctic Ocean may be an important source of nitrogen to a seasonally nitrogen‐limited system. If widespread in surface waters over ice‐free shelves throughout the Arctic, N2 fixation could contribute up to 3.5 Tg N yr−1 to the Arctic nitrogen budget. At these rates, N2 fixation occurring in ice‐free summer waters would offset up to 27.1% of the Arctic denitrification deficit and contribute an additional 2.7% to N2 fixation globally, making it an important consideration in the current debate of whether nitrogen in the global ocean is in steady state. Additional investigations of high‐latitude marine diazotrophic physiology are required to refine these N2 fixation estimates.

Published
2017
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16. Late‐season nitrogen uptake across the western coastal Alaskan Arctic.

Author

Stanley, Brianna C., Sipler, Rachel E., Roberts, Quinn N., Spackeen, Jenna L., Norton, E. Zane, and Bronk, Deborah A.

Subjects
CONTINENTAL shelf, TUNDRAS, CARBON cycle, AMINO acids, MICROBIAL communities, NITROGEN, UREA as fertilizer, SUMMER
Abstract

Productivity in the Arctic is expected to increase as temperatures and the number of open water days rise. With this increased productivity, the coastal shelves of the Arctic Ocean may act as a sink for atmospheric carbon. However, this storage is dependent on a sufficient nitrogen (N) supply and current literature on biogeochemical rates of N uptake in this region is severely limited. Here, we report the spatial extent and rate at which the aquatic microbial community utilizes inorganic and organic N substrates in the Alaskan Arctic during late summer. Uptake rates (> 0.3 μm) were measured in 2016 and 2017 using isotopically labeled ammonium (NH4+), nitrate (NO3−), urea, and mixed algal amino acids. Rates of NH4+ regeneration were also measured to investigate the contribution of remineralized N to primary production. Primary production was estimated using isotopically labeled bicarbonate. We found that N species uptake varied by location. Although NH4+ was the form of N taken up at the greatest rate at most sites, we also found that uptake rates of urea could be greater than NO3− and that amino acid uptake was widespread. Supporting previous studies, NO3− uptake rates were correlated with primary production rates. Variability in nutrient reservoirs and sampling conditions in the Chukchi Sea between the 2 yr were responsible for some of the variances observed in estimated NH4+ recycling rates and primary production. Understanding which N sources support this late‐season primary production requires obtaining uptake rates for a diverse range of inorganic and organic N substrates. [ABSTRACT FROM AUTHOR]

Published
2023
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20. A Nonparametric Approach to Estimate Classification Accuracy and Consistency

Author

Lathrop, Quinn N. and Cheng, Ying

Abstract

When cut scores for classifications occur on the total score scale, popular methods for estimating classification accuracy (CA) and classification consistency (CC) require assumptions about a parametric form of the test scores or about a parametric response model, such as item response theory (IRT). This article develops an approach to estimate CA and CC nonparametrically by replacing the role of the parametric IRT model in Lee's classification indices with a modified version of Ramsay's kernel-smoothed item response functions. The performance of the nonparametric CA and CC indices are tested in simulation studies in various conditions with different generating IRT models, test lengths, and ability distributions. The nonparametric approach to CA often outperforms Lee's method and Livingston and Lewis's method, showing robustness to nonnormality in the simulated ability. The nonparametric CC index performs similarly to Lee's method and outperforms Livingston and Lewis's method when the ability distributions are nonnormal.

Published
2014
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23. Two Approaches to Estimation of Classification Accuracy Rate under Item Response Theory

Author

Lathrop, Quinn N. and Cheng, Ying

Abstract

Within the framework of item response theory (IRT), there are two recent lines of work on the estimation of classification accuracy (CA) rate. One approach estimates CA when decisions are made based on total sum scores, the other based on latent trait estimates. The former is referred to as the Lee approach, and the latter, the Rudner approach, each after its representative contributor. In this article, the two approaches are delineated in the same framework to highlight their similarities and differences. In addition, a simulation study manipulating IRT model, sample size, test length, and cut score location was conducted. The study investigated the empirical CA that can be achieved using either the total scores or the latent trait estimates. It also evaluated the performances of the two approaches in estimating their respective empirical CAs. Results on the empirical CA suggest that when the model fits, classifications made with the latent trait estimate shall be equally or more accurate than classifications made with total score. The magnitude of difference was governed by divergence from the one-parameter logistic (1PL) model. Both Lee and Rudner approaches provided good estimates of their respective empirical CAs for every condition that was simulated. Practical implications of the simulation results are discussed. (Contains 4 tables, 5 figures, and 1 note.)

Published
2013
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25. Microbial Community Response to Terrestrially Derived Dissolved Organic Matter in the Coastal Arctic

Author

Rachel E. Sipler, Colleen T. E. Kellogg, Tara L. Connelly, Quinn N. Roberts, Patricia L. Yager, and Deborah A. Bronk

Subjects
dissolved organic matter, bacterial diversity, Arctic, Chukchi Sea, microbial community composition, tDOM, Microbiology, QR1-502
Abstract

Warming at nearly twice the global rate, higher than average air temperatures are the new ‘normal’ for Arctic ecosystems. This rise in temperature has triggered hydrological and geochemical changes that increasingly release carbon-rich water into the coastal ocean via increased riverine discharge, coastal erosion, and the thawing of the semi-permanent permafrost ubiquitous in the region. To determine the biogeochemical impacts of terrestrially derived dissolved organic matter (tDOM) on marine ecosystems we compared the nutrient stocks and bacterial communities present under ice-covered and ice-free conditions, assessed the lability of Arctic tDOM to coastal microbial communities from the Chukchi Sea, and identified bacterial taxa that respond to rapid increases in tDOM. Once thought to be predominantly refractory, we found that ∼7% of dissolved organic carbon and ∼38% of dissolved organic nitrogen from tDOM was bioavailable to receiving marine microbial communities on short 4 – 6 day time scales. The addition of tDOM shifted bacterial community structure toward more copiotrophic taxa and away from more oligotrophic taxa. Although no single order was found to respond universally (positively or negatively) to the tDOM addition, this study identified 20 indicator species as possible sentinels for increased tDOM. These data suggest the true ecological impact of tDOM will be widespread across many bacterial taxa and that shifts in coastal microbial community composition should be anticipated.

Published
2017
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27. VizieR Online Data Catalog: Triton light curves from 05/10/2017 (Marques Oliveira+, 2022)

Author

Marques Oliveira, J., Sicardy, B., Gomes-Junior, A. R., Ortiz, J. L., Strobel, D. F., Bertrand, T., Forget, F., Lellouch, E., Desmars, J., Berard, D., Doressoundiram, A., Lecacheux, J., Leiva, R., Meza, E., Roques, F., Souami, D., Widemann, T., Santos-Sanz, P., Morales, N., Duffard, R., Fernandez-Valenzuela, E., Castro-Tirado, A. J., Braga-Ribas, F., Morgado, B. E., Assafin, M., Camargo, J. I. B., Vieira-Martins, R., Benedetti-Rossi, G., Santos-Filho, S., Banda-Huarca, M. V., Quispe-Huaynasi, F., Pereira, C. L., Rommel, F. L., Margoti, G., Dias-Oliveira, A., Colas, F., Berthier, J., Renner, S., Hueso, R., Perez-Hoyos, S., Sanchez-Lavega, A., Rojas, J. F., Beisker, W., Kretlow, M., Herald, D., Gault, D., Bath, K.-L., Bode, H.-J., Bredner, E., Guhl, K., Haymes, T. V., Hummel, E., Kattentidt, B., Klos, O., Pratt, A., Thome, B., Avdellidou, C., Gazeas, K., Karampotsiou, E., Tzouganatos, L., Kardasis, E., Christou, A. A., Xilouris, E. M., Alikakos, I., Gourzelas, A., Liakos, A., Charmandaris, V., Jelinek, M., Strobl, J., Eberle, A., Rapp, K., Gahrken, B., Kowo Llik, S., Bitzer, R., Miller, M., Herzogenrath, G., Frangenberg, D., Brandis, L., Puetz, I., Perdelwitz, V., Piehler, G. M., Riepe, P., von Poschinger, K., Baruffetti, P., Cenadelli, D., Christille, J.-M., Ciabattari, F., Di, Luca R., Alboresi, D., Leto, G., Zanmar Sanchez, R., Bruno, P., Occhipinti, G., Morrone, L., Cupolino, L., Noschese, A., Vecchione, A., Scalia, C., Lo Savio, R., Giardina, G., Kamoun, S., Barbosa, R., Behrend, R., Spano, M., Bouchet, E., Cottier, M., Falco, L., Gallego, S., Tortorelli, L., Sposetti, S., Sussenbach, J., van den Abbeel, F., Andre, P., Llibre, M., Pailler, F., Ardissone, J., Boutet, M., Sanchez, J., Bretton, M., Cailleau, A., Pic, V., Granier, L., Chauvet, R., Conjat, M., Dauvergne, J. L., Dechambre, O., Delay, P., Delcroix, M., Rousselot, L., Ferreira, J., Machado, P., Tanga, P., Rivet, J.-P., Frappa, E., Irzyk, M., Jabet, F., Kaschinski, M., Klotz, A., Rieugnie, Y., Klotz, A. N., Labrevoir, O., Lavandier, D., Walliang, D., Leroy, A., Bouley, S., Lisciandra, S., Coliac, J.-F., Metz, F., Erpelding, D., Nougayrede, P., Miniou, M., Moindrot, S., Morel, P., Reginato, B., Reginato, E., Rudelle, J., Tregon, B., Tanguy, R., David, J., Thuillot, W., Hestroffer, D., Vaudescal, G., Baba Aissa, D., Grigahcene, Z., Briggs, D., Broadbent, S., Denyer, P., Haigh, N. J., Quinn, N., Thurston, G., Fossey, S. J., Arena, C., Jennings, M., Talbot, J., Alonso, S., Roman Reche, A., Casanova, V., Briggs, E., Iglesias-Marzoa, R., Abril Ibanez, J., Diaz, Martin M. C., Gonzalez, H., Maestre Garcia, J. L., Marchant, J., Ordonez-Etxeberria, I., Martorell, P., Salamero, J., Organero, F., Ana, L., Fonseca, F., Peris, V., Brevia, O., Selva, A., Perello, C., Cabedo, V., Goncalves, R., Ferreira, M., Marques Dias, F., Daassou, A., Barkaoui, K., Benkhaldoun, Z., Guennoun, M., Chouqar, J., Jehin, E., Rinner, C., Lloyd, J., El Moutamid, M., Lamarche, C., Pollock, J. T., Caton, D. B., Kouprianov, V., Timerson, B. W., Blanchard, G., Payet, B., Peyrot, A., Teng-Chuen-Yu, J.-P., Francoise, J., Mondon, B., Payet, T., Boissel, C., Castets, M., Hubbard, W. B., Hill, R., Reitsema, H. J., Mousis, O., Ball, L., Hutcheon, S., Lay, K., Anderson, P., Moy, M., Jonsen, M., Pink, I., Walters, R., Downs, B., Institut de Mécanique Céleste et de Calcul des Ephémérides (IMCCE), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Lille-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Photometry, Planets, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Solar system
Abstract

International audience; The data provided features all light curves from the 5 October 2017 event. The names of the files are the same names, in lower caps and with no spaces, that are presented in Figures C.1 and C.2. The first column of all files is the time in seconds, starting on 5 October 2017 00:00:00 UTC. The second column of all files is the normalised flux, where the unocculted flux oscillates around 1. (2 data files).

Published
2022

29. The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy

Author

Wenning, G.K. Stankovic, I. Vignatelli, L. Fanciulli, A. Calandra-Buonaura, G. Seppi, K. Palma, J.-A. Meissner, W.G. Krismer, F. Berg, D. Cortelli, P. Freeman, R. Halliday, G. Höglinger, G. Lang, A. Ling, H. Litvan, I. Low, P. Miki, Y. Panicker, J. Pellecchia, M.T. Quinn, N. Sakakibara, R. Stamelou, M. Tolosa, E. Tsuji, S. Warner, T. Poewe, W. Kaufmann, H.

Subjects
nervous system, stomatognathic system, parasitic diseases, mental disorders, nervous system diseases
Abstract

Background: The second consensus criteria for the diagnosis of multiple system atrophy (MSA) are widely recognized as the reference standard for clinical research, but lack sensitivity to diagnose the disease at early stages. Objective: To develop novel Movement Disorder Society (MDS) criteria for MSA diagnosis using an evidence-based and consensus-based methodology. Methods: We identified shortcomings of the second consensus criteria for MSA diagnosis and conducted a systematic literature review to answer predefined questions on clinical presentation and diagnostic tools relevant for MSA diagnosis. The criteria were developed and later optimized using two Delphi rounds within the MSA Criteria Revision Task Force, a survey for MDS membership, and a virtual Consensus Conference. Results: The criteria for neuropathologically established MSA remain unchanged. For a clinical MSA diagnosis a new category of clinically established MSA is introduced, aiming for maximum specificity with acceptable sensitivity. A category of clinically probable MSA is defined to enhance sensitivity while maintaining specificity. A research category of possible prodromal MSA is designed to capture patients in the earliest stages when symptoms and signs are present, but do not meet the threshold for clinically established or clinically probable MSA. Brain magnetic resonance imaging markers suggestive of MSA are required for the diagnosis of clinically established MSA. The number of research biomarkers that support all clinical diagnostic categories will likely grow. Conclusions: This set of MDS MSA diagnostic criteria aims at improving the diagnostic accuracy, particularly in early disease stages. It requires validation in a prospective clinical and a clinicopathological study. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Published
2022

30. Constraints on the structure and seasonal variations of Triton's atmosphere from the 5 October 2017 stellar occultation and previous observations

Author

Marques Oliveira, J. Sicardy, B. Gomes-Júnior, A.R. Ortiz, J.L. Strobel, D.F. Bertrand, T. Forget, F. Lellouch, E. Desmars, J. Bérard, D. Doressoundiram, A. Lecacheux, J. Leiva, R. Meza, E. Roques, F. Souami, D. Widemann, T. Santos-Sanz, P. Morales, N. Duffard, R. Fernández-Valenzuela, E. Castro-Tirado, A.J. Braga-Ribas, F. Morgado, B.E. Assafin, M. Camargo, J.I.B. Vieira-Martins, R. Benedetti-Rossi, G. Santos-Filho, S. Banda-Huarca, M.V. Quispe-Huaynasi, F. Pereira, C.L. Rommel, F.L. Margoti, G. Dias-Oliveira, A. Colas, F. Berthier, J. Renner, S. Hueso, R. Pérez-Hoyos, S. Sánchez-Lavega, A. Rojas, J.F. Beisker, W. Kretlow, M. Herald, D. Gault, D. Bath, K.-L. Bode, H.-J. Bredner, E. Guhl, K. Haymes, T.V. Hummel, E. Kattentidt, B. Klös, O. Pratt, A. Thome, B. Avdellidou, C. Gazeas, K. Karampotsiou, E. Tzouganatos, L. Kardasis, E. Christou, A.A. Xilouris, E.M. Alikakos, I. Gourzelas, A. Liakos, A. Charmandaris, V. Jelínek, M. Štrobl, J. Eberle, A. Rapp, K. Gährken, B. Klemt, B. Kowollik, S. Bitzer, R. Miller, M. Herzogenrath, G. Frangenberg, D. Brandis, L. Pütz, I. Perdelwitz, V. Piehler, G.M. Riepe, P. Von Poschinger, K. Baruffetti, P. Cenadelli, D. Christille, J.-M. Ciabattari, F. Di Luca, R. Alboresi, D. Leto, G. Zanmar Sanchez, R. Bruno, P. Occhipinti, G. Morrone, L. Cupolino, L. Noschese, A. Vecchione, A. Scalia, C. Lo Savio, R. Giardina, G. Kamoun, S. Barbosa, R. Behrend, R. Spano, M. Bouchet, E. Cottier, M. Falco, L. Gallego, S. Tortorelli, L. Sposetti, S. Sussenbach, J. Van Den Abbeel, F. André, P. Llibre, M. Pailler, F. Ardissone, J. Boutet, M. Sanchez, J. Bretton, M. Cailleau, A. Pic, V. Granier, L. Chauvet, R. Conjat, M. Dauvergne, J.L. Dechambre, O. Delay, P. Delcroix, M. Rousselot, L. Ferreira, J. MacHado, P. Tanga, P. Rivet, J.-P. Frappa, E. Irzyk, M. Jabet, F. Kaschinski, M. Klotz, A. Rieugnie, Y. Klotz, A.N. Labrevoir, O. Lavandier, D. Walliang, D. Leroy, A. Bouley, S. Lisciandra, S. Coliac, J.-F. Metz, F. Erpelding, D. Nougayrède, P. Midavaine, T. Miniou, M. Moindrot, S. Morel, P. Reginato, B. Reginato, E. Rudelle, J. Tregon, B. Tanguy, R. David, J. Thuillot, W. Hestroffer, D. Vaudescal, G. Baba Aissa, D. Grigahcene, Z. Briggs, D. Broadbent, S. Denyer, P. Haigh, N.J. Quinn, N. Thurston, G. Fossey, S.J. Arena, C. Jennings, M. Talbot, J. Alonso, S. Román Reche, A. Casanova, V. Briggs, E. Iglesias-Marzoa, R. Abril Ibáñez, J. Díaz Martín, M.C. González, H. Maestre García, J.L. Marchant, J. Ordonez-Etxeberria, I. Martorell, P. Salamero, J. Organero, F. Ana, L. Fonseca, F. Peris, V. Brevia, O. Selva, A. Perello, C. Cabedo, V. Gonçalves, R. Ferreira, M. Marques Dias, F. Daassou, A. Barkaoui, K. Benkhaldoun, Z. Guennoun, M. Chouqar, J. Jehin, E. Rinner, C. Lloyd, J. El Moutamid, M. Lamarche, C. Pollock, J.T. Caton, D.B. Kouprianov, V. Timerson, B.W. Blanchard, G. Payet, B. Peyrot, A. Teng-Chuen-Yu, J.-P. Françoise, J. Mondon, B. Payet, T. Boissel, C. Castets, M. Hubbard, W.B. Hill, R. Reitsema, H.J. Mousis, O. Ball, L. Neilsen, G. Hutcheon, S. Lay, K. Anderson, P. Moy, M. Jonsen, M. Pink, I. Walters, R. Downs, B.

Abstract

Context. A stellar occultation by Neptune's main satellite, Triton, was observed on 5 October 2017 from Europe, North Africa, and the USA. We derived 90 light curves from this event, 42 of which yielded a central flash detection. Aims. We aimed at constraining Triton's atmospheric structure and the seasonal variations of its atmospheric pressure since the Voyager 2 epoch (1989). We also derived the shape of the lower atmosphere from central flash analysis. Methods. We used Abel inversions and direct ray-tracing code to provide the density, pressure, and temperature profiles in the altitude range ∼8 km to ∼190 km, corresponding to pressure levels from 9 μbar down to a few nanobars. Results. (i) A pressure of 1.18 ± 0.03 μbar is found at a reference radius of 1400 km (47 km altitude). (ii) A new analysis of the Voyager 2 radio science occultation shows that this is consistent with an extrapolation of pressure down to the surface pressure obtained in 1989. (iii) A survey of occultations obtained between 1989 and 2017 suggests that an enhancement in surface pressure as reported during the 1990s might be real, but debatable, due to very few high S/N light curves and data accessible for reanalysis. The volatile transport model analysed supports a moderate increase in surface pressure, with a maximum value around 2005-2015 no higher than 23 μbar. The pressures observed in 1995-1997 and 2017 appear mutually inconsistent with the volatile transport model presented here. (iv) The central flash structure does not show evidence of an atmospheric distortion. We find an upper limit of 0.0011 for the apparent oblateness of the atmosphere near the 8 km altitude. ©

Published
2022

34. A New Cataclysmic Variable in Hercules

Author

Price, A., Gary, B., Bedient, J., Cook, L., Templeton, M., Pullen, C., Starkey, D., Crawford, T., Corlan, R., Dvorak, S., Graham, K., Huziak, R., James, R., Messier, D., Quinn, N., Boyd, D., Blackwell, J., Walker, G., Mattei, M., Rodriguez, D., Simonsen, M., Henden, A., Vanmunster, T., Garnavich, P., Pittichová, J., Matheson, T., Challis, P., Kirshner, R. P., Adams, E., Harrison, T., Koppelman, M. D., Sarty, G. E., and Mais, D. E.

Published
2004
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38. Clinical characteristics of long-term survivors in multiple system atrophy: An analysis of the EMSA-SG registry: 299

Author

Krismer, F., Duerr, S., Seppi, K., Scherfler, C., Boesch, S., Ostergaard, K., Dupont, E., Tolosa, E., Cardozo, A., Klockgether, T., Abele, M., Tison, F., Yekhlef, F., Deuschl, G., Daniels, C., Sampaio, C., Coelho, M., Quinn, N., Bozi, M., Schrag, A., Mathias, C. J., Fowler, C., Widner, H., Nilsson, C. F., Oertel, W., Schimke, N., Albanese, A., del Sorbo, F., Barone, P., Pellecchia, M. T., Djaldetti, R., Colosimo, C., Meco, G., Gonzalez-Mandly, A., Berciano, J., Gurevich, T., Giladi, N., Rascol, O., Galitzky, M., Gasser, T., Kamm, C., Poewe, W., and Wenning, G. K.

Published
2014

41. Thoracolumbar spinal fixation for camptocormia in Parkinson's disease

Author

Peek, A.C., Quinn, N., Casey, A.T.H., and Etherington, G.

Subjects
Parkinson's disease -- Care and treatment, Parkinson's disease -- Case studies, Spine -- Surgery, Spine -- Patient outcomes, Spine -- Case studies, Health, Psychology and mental health
Published
2009

45. The European Multiple System Atrophy-Study Group (EMSA-SG)

Author

Geser, F., Seppi, K., Stampfer-Kountchev, M., Köllensperger, M., Diem, A., Ndayisaba, J. P., Ostergaard, K., Dupont, E., Cardozo, A., Tolosa, E., Abele, M., Dodel, R., Klockgether, T., Ghorayeb, I., Yekhlef, F., Tison, F., Daniels, C., Kopper, F., Deuschl, G., Coelho, M., Ferreira, J., Rosa, M. M., Sampaio, C., Bozi, M., Schrag, A., Hooker, J., Kim, H., Scaravilli, T., Mathias, C. J., Fowler, C., Wood, N., Quinn, N., Widner, H., Nilsson, C. F., Lindvall, O., Schimke, N., Eggert, K. M., Oertel, W., del Sorbo, F., Carella, F., Albanese, A., Pellecchia, M. T., Barone, P., Djaldetti, R., Meco, G., Colosimo, C., Gonzalez-Mandly, A., Berciano, J., Gurevich, T., Giladi, N., Galitzky, M., Ory, F., Rascol, O., Kamm, C., Buerk, K., Maaß, S., Gasser, T., Poewe, W., Wenning, G. K., and on behalf of the EMSA-SG

Published
2005
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46. The (alpha)-synuclein gene in multiple system atrophy

Author

Ozawa, T., Healy, D.G., Abou-Sleiman, P.M., Ahmadi, K.R., Quinn, N., Lees, A.J., Shaw, K., Wullner, U., Berciano, J., Moller, J.C., Kamm, C., Burk, K., Josephs, K.A., Barone, P., Tolosa, E., Goldstein, D.B., Wenning, G., Geser, F., Holton, J.L., Gasser, T., Revesz, T., and Wood, N.W.

Subjects
Atrophy -- Genetic aspects, Atrophy -- Development and progression, Gene expression -- Research, Health, Psychology and mental health
Published
2006

47. Parkinsonism following bilateral lesions of the globus pallidus: performance on a variety of motor tasks show similarities with Parkinson's disease

Author

Rothwell, J.C., Brown, R.G., Quinn, N., Bhatia, K.P., and Jahanshahi, M.

Subjects
Parkinsonism, Symptomatic -- Causes of, Parkinsonism, Symptomatic -- Observations, Drinking behavior -- Observations, Drinking behavior -- Abnormalities, Drinking behavior -- Complications and side effects, Cognition disorders -- Causes of, Cognition disorders -- Observations, Health, Psychology and mental health
Published
2005

49. Tay gene and Parkinson's disease: a case-control study and meta-analysis

Author

Healy, D.G., Abou-Sleiman, P.M., Lees, A.J., Casas, J.P., Quinn, N., Bhatia, K., Hingorani, A.D., and Wood, N.W.

Subjects
Genes -- Research, Genes -- Analysis, Parkinson's disease -- Research, Parkinson's disease -- Risk factors, Parkinson's disease -- Analysis, Health, Psychology and mental health
Published
2004

50. Parkin disease – a clinicopathological entity?: O10

Author

Doherty, K. M., Silveira-Moriyama, L., Parkkinen, L., Healy, D. G., Farrell, M., Mencacci, N. E., Ahmed, Z., Brett, F. M., Hardy, J., Quinn, N., Counihan, T. J., Lynch, T., Fox, Z. V., Revesz, T., Lees, A. J., and Holton, J. L.

Published
2013

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