391 results on '"Quesnel, Bruno"'
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2. Deciphering genetic and nongenetic factors underlying tumour dormancy: insights from multiomics analysis of two syngeneic MRD models of melanoma and leukemia
3. Key role of glutamine metabolism in persistence of leukemic cells upon exposition to FLT3 tyrosine kinase inhibitors
4. Genomic profiling of mycosis fungoides identifies patients at high risk of disease progression
5. MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma
6. Single-agent 5-azacytidine as post-transplant maintenance in high-risk myeloid malignancies undergoing allogeneic hematopoietic cell transplantation
7. Resurgence of myeloproliferative neoplasm in patients in remission from blast transformation after treatment with hypomethylating agents
8. Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction
9. Machine learning identifies the independent role of dysplasia in the prediction of response to chemotherapy in AML
10. TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence
11. Antimetabolic cooperativity with the clinically approved l-asparaginase and tyrosine kinase inhibitors to eradicate CML stem cells
12. How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?
13. Disease escape with the selective loss of the Philadelphia chromosome after tyrosine kinase inhibitor exposure in Ph-positive acute lymphoblastic leukemia
14. Familial myeloid malignancies with germline TET2 mutation
15. Induction of AML cell differentiation using HOXA9/DNA binding inhibitors as a potential therapeutic option for HOXA9‐dependent AML.
16. Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study
17. Quantification of EVI1 transcript levels in acute myeloid leukemia by RT-qPCR analysis: A study by the ALFA Group
18. Isolation and characterization of two canine melanoma cell lines: new models for comparative oncology
19. Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia
20. Outcome of patients with high risk Myelodysplastic Syndrome (MDS) and advanced Chronic Myelomonocytic Leukemia (CMML) treated with decitabine after azacitidine failure
21. Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors
22. Phase I Population Pharmacokinetic Assessment of the Oral Bromodomain Inhibitor OTX015 in Patients with Haematologic Malignancies
23. Azacitidine in the treatment of therapy related myelodysplastic syndrome and acute myeloid leukemia (tMDS/AML): A report on 54 patients by the Groupe Francophone Des Myelodysplasies (GFM)
24. MYD88 L265P mutation in Waldenstrom macroglobulinemia
25. Metabolites of tryptophan catabolism are elevated in sera of patients with myelodysplastic syndromes and inhibit hematopoietic progenitor amplification
26. Tumor Necrosis Factor-Alpha/Tumor Necrosis Factor-Alpha Receptor 1 Signaling Pathway Leads to Thymocytes' Cell Death by Necroptosis in a Mouse Model of Acute Myeloid Leukemia.
27. Involvement of a common progenitor cell in core binding factor acute myeloid leukaemia associated with mastocytosis
28. Outcome of treatment after first relapse in younger adults with acute myeloid leukemia initially treated by the ALFA-9802 trial
29. A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q
30. Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine
31. Synthesis and biological evaluation of phenstatin metabolites
32. Genomic characterization of Imatinib resistance in CD34 + cell populations from chronic myeloid leukaemia patients
33. IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.
34. Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM)
35. Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia
36. TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)
37. Activity of elaeochytrin A from Ferula elaeochytris on leukemia cell lines
38. Dormant tumor cells as a therapeutic target?
39. In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors
40. Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study
41. MYD88 L265P mutation contributes to the diagnosis of Bing Neel syndrome
42. Azacitidine in untreated acute myeloid leukemia: A report on 149 patients
43. Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors.
44. Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia
45. Efficient generation of antileukemic autologous T cells by short-term culture and γ-irradiation of myeloid leukemic cells
46. Genome wide SNP array identified multiple mechanisms of genetic changes in Waldenstrom macroglobulinemia
47. Administration of alemtuzumab and G-CSF to adults with relapsed or refractory acute lymphoblastic leukemia: results of a phase II study
48. Outcome of older patients with acute myeloid leukemia in first relapse
49. Long-term follow-up of European APL 2000 trial, evaluating the role of cytarabine combined with ATRA and Daunorubicin in the treatment of nonelderly APL patients
50. Involvement of ORAI1/SOCE in Human AML Cell Lines and Primary Cells According to ABCB1 Activity, LSC Compartment and Potential Resistance to Ara-C Exposure.
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