Search

Gastrodia elata Blume (G. elata), listed as one of the 34 precious Chinese medicines, servers a dual purpose as both a medicinal herb and a food source. Polysaccharide is the main active ingredient in G. elata, which has pharmacological activities such as immune regulation, anti-oxidation, anticancer, anti-aging, neuroprotection and antibacterial activity and so on. The biological activities of G. elata polysaccharide (GPs) is closely related to its chemical structures. However, no a review has synthetically summarized the chemical structures and pharmacological activities of GPs. This study delves into the chemical structures, pharmacological action of GPs, offering insights for the future development an application of these compounds. [ABSTRACT FROM AUTHOR]

A rolling force model is established by using the unified yield criterion, in which both the changes of the slab temperature and the radius of the roller are considered. In order to solve the integral problem of the nonlinear specific plastic work rate, the unified yield criterion is used to analyse a simplified velocity field, and the internal deformation power is derived. Then, the shear power and friction power are also calculated based on the velocity field, and the total power is obtained by summarising these derived formulas. Finally, the analytic solution of rolling force in terms of the unified yield criterion is obtained by the variational method. Thereafter, the measured data from one domestic factory is used to check the analytical solution of rolling force, in which the temperature drop from the slab inlet to its outlet is considered. Meanwhile, the roller flattening is also considered. It is shown from the comparison and discussion that: the Mises yield criterion that is a special case of the unified yield criterion is more accurate in predicting the rolling force; the thinner the slab is, the more the temperature drop is; the calculation results by considering the roll flattening are improved. [ABSTRACT FROM AUTHOR]

Two new sesquiterpene glycosides, 8 α ,12,15 β -trihydroxycopacamphan-15- O - β -D-glucopyranoside ( 1 ) and dendrobiumane C-11- O - β -D-glucopyranoside ( 2 ), along with three known terpenoids ( 3-5 ) were isolated from the aerial stems of Dendrobium henanense . Their structures were elucidated based on NMR-spectroscopic and HR-MS analyses. All compounds could reduce the levels of NO, TNF- α and IL-1 β in LPS-induced RAW264.7 cells with IC 50 values ranging from 10.37 to 34.55 µ Μ.