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13. Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis

Author

Toloza, Freddy J K, Derakhshan, Arash, Männistö, Tuija, Bliddal, Sofie, Popova, Polina V, Carty, David M, Chen, Liangmiao, Taylor, Peter, Mosso, Lorena, Oken, Emily, Suvanto, Eila, Itoh, Sachiko, Kishi, Reiko, Bassols, Judit, Auvinen, Juha, López-Bermejo, Abel, Brown, Suzanne J, Boucai, Laura, Hisada, Aya, Yoshinaga, Jun, Shilova, Ekaterina, Grineva, Elena N, Vrijkotte, Tanja G M, Sunyer, Jordi, Jiménez-Zabala, Ana, Riaño-Galan, Isolina, Lopez-Espinosa, Maria-Jose, Prokop, Larry J, Singh Ospina, Naykky, Brito, Juan P, Rodriguez-Gutierrez, Rene, Alexander, Erik K, Chaker, Layal, Pearce, Elizabeth N, Peeters, Robin P, Feldt-Rasmussen, Ulla, Guxens, Mònica, Chatzi, Leda, Delles, Christian, Roeters van Lennep, Jeanine E, Pop, Victor J M, Lu, Xuemian, Walsh, John P, Nelson, Scott M, Korevaar, Tim I M, and Maraka, Spyridoula

Published
2022
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18. Dismantling, optimising, and personalising internet cognitive behavioural therapy for depression: a systematic review and component network meta-analysis using individual participant data

Author

Furukawa, Toshi A, Suganuma, Aya, Ostinelli, Edoardo G, Andersson, Gerhard, Beevers, Christopher G, Shumake, Jason, Berger, Thomas, Boele, Florien Willemijn, Buntrock, Claudia, Carlbring, Per, Choi, Isabella, Christensen, Helen, Mackinnon, Andrew, Dahne, Jennifer, Huibers, Marcus J H, Ebert, David D, Farrer, Louise, Forand, Nicholas R, Strunk, Daniel R, Ezawa, Iony D, Forsell, Erik, Kaldo, Viktor, Geraedts, Anna, Gilbody, Simon, Littlewood, Elizabeth, Brabyn, Sally, Hadjistavropoulos, Heather D, Schneider, Luke H, Johansson, Robert, Kenter, Robin, Kivi, Marie, Björkelund, Cecilia, Kleiboer, Annet, Riper, Heleen, Klein, Jan Philipp, Schröder, Johanna, Meyer, Björn, Moritz, Steffen, Bücker, Lara, Lintvedt, Ove, Johansson, Peter, Lundgren, Johan, Milgrom, Jeannette, Gemmill, Alan W, Mohr, David C, Montero-Marin, Jesus, Garcia-Campayo, Javier, Nobis, Stephanie, Zarski, Anna-Carlotta, O'Moore, Kathleen, Williams, Alishia D, Newby, Jill M, Perini, Sarah, Phillips, Rachel, Schneider, Justine, Pots, Wendy, Pugh, Nicole E, Richards, Derek, Rosso, Isabelle M, Rauch, Scott L, Sheeber, Lisa B, Smith, Jessica, Spek, Viola, Pop, Victor J, Ünlü, Burçin, van Bastelaar, Kim M P, van Luenen, Sanne, Garnefski, Nadia, Kraaij, Vivian, Vernmark, Kristofer, Warmerdam, Lisanne, van Straten, Annemieke, Zagorscak, Pavle, Knaevelsrud, Christine, Heinrich, Manuel, Miguel, Clara, Cipriani, Andrea, Efthimiou, Orestis, Karyotaki, Eirini, and Cuijpers, Pim

Published
2021
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19. Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis

Author

Derakhshan, Arash, Peeters, Robin P, Taylor, Peter N, Bliddal, Sofie, Carty, David M, Meems, Margreet, Vaidya, Bijay, Chen, Liangmiao, Knight, Bridget A, Ghafoor, Farkhanda, Popova, Polina V, Mosso, Lorena, Oken, Emily, Suvanto, Eila, Hisada, Aya, Yoshinaga, Jun, Brown, Suzanne J, Bassols, Judit, Auvinen, Juha, Bramer, Wichor M, López-Bermejo, Abel, Dayan, Colin M, French, Robert, Boucai, Laura, Vafeiadi, Marina, Grineva, Elena N, Pop, Victor J M, Vrijkotte, Tanja G, Chatzi, Leda, Sunyer, Jordi, Jiménez-Zabala, Ana, Riaño, Isolina, Rebagliato, Marisa, Lu, Xuemian, Pirzada, Amna, Männistö, Tuija, Delles, Christian, Feldt-Rasmussen, Ulla, Alexander, Erik K, Nelson, Scott M, Chaker, Layal, Pearce, Elizabeth N, Guxens, Mònica, Steegers, Eric A P, Walsh, John P, and Korevaar, Tim I M

Published
2020
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29. High first trimester ferritin levels differ according to parity and are independently related to preterm birth: A prospective cohort study.

Author

Broekhuis, Annabel, Koenen, Steven V., Broeren, Maarten A. C., Krabbe, Johannes G., and Pop, Victor J. M.

Subjects
PREMATURE labor, FERRITIN, COHORT analysis, LOGISTIC regression analysis, LONGITUDINAL method, CHORIOAMNIONITIS
Abstract

Introduction: A considerable amount of neonatal morbidity and mortality worldwide is caused by preterm birth. To date, the underlying etiology of preterm birth has not been fully clarified. Previous studies demonstrate that inflammation is one of the pathological factors that might cause preterm birth, and that there is a difference between primiparous and multiparous women in immune response to pregnancy. The objective of this prospective cohort study was to investigate the role of two inflammatory markers, ferritin and C‐reactive protein (CRP) and preterm birth, in first trimester women, stratified for parity. In addition, a possible association between high ferritin and CRP, and a possible association between high ferritin and CRP and preterm birth were assessed. Material and methods: A total of 2044 healthy, low‐risk pregnant women from primary obstetric care in the Netherlands participated in this study. Their ferritin and CRP levels were evaluated at 12 weeks' gestation. Levels above the parity specific 95th percentile were defined as high. The main outcome of this study was to assess the presence of a possible association between parity specific high ferritin and CRP, and preterm birth. The secondary outcomes were the ferritin and CRP levels of women, stratified for parity, and the possible association between high ferritin and CRP levels. Logistic regression analysis was performed with preterm birth as a dependent variable and parity specific high ferritin and CRP as an independent variable, adjusting for age and history of preterm birth. Results: Ferritin levels decreased with increasing parity. Ferritin and CRP levels at 12 weeks' gestation were significantly higher in women with preterm birth. In primiparous women, high ferritin levels (OR: 2.5, CI: 1.14–5.38) and high CRP levels (OR: 5.0, CI: 2.61–9.94) were independently associated with preterm birth. In multiparous women, high ferritin levels (OR: 6.0, CI: 2.28–16.67) were independently associated with preterm birth while high CRP levels were not. Conclusions: First trimester parity specific ferritin and CRP levels could play a part in predictive models for preterm birth, and further research for their additive role in preterm birth is needed. [ABSTRACT FROM AUTHOR]

Published
2024
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38. Prediction of cardiovascular events in older patients with hypertension in primary care: a cohort study.

Author

de Hartog-Keyzer, Josephine ML, Pop, Victor JM, Rodwell, Laura, Nijveldt, Robin, and Messaoudi, Saloua El

Abstract

Background: Accurate risk stratification identifying patients with hypertension at risk of future cardiovascular disease in primary care would be desirable. Aim: To investigate the association between elevated brain natriuretic peptide (BNP), left ventricular hypertrophy (LVH) on an electrocardiogram (ECG), and LVH on an echocardiogram and the development of cardiovascular events (CVEs), especially heart failure and all-cause mortality (ACM), in a primary care population with hypertension without symptoms of heart failure. Design and setting: A prospective cohort study in five Dutch general practices between 2010–2012 and 2020. Method: In total, 530 patients (aged 60–85 years) underwent laboratory testing, ECGs, and echocardiograms at baseline. The incidence of new CVEs and ACM at up to 9 years' follow-up was recorded by data extraction from the digital information systems. Results: Among the 530 participants, 31 (5.8%) developed a coronary event, 44 (8.3%) a cerebrovascular accident, 53 (10.0%) atrial fibrillation, 23 (4.3%) heart failure, and 66 (12.5%) died. Cox regression analyses, adjusting for relevant Framingham covariates, showed that elevated BNP increased the risk of ACM, CVEs, and specifically heart failure independently by 44% (hazard ratio [HR] 1.44, 95% confidence interval [CI] = 1.07 to 1.94, P = −0.017), 45% (HR 1.45, 95% CI = 1.15 to 1.82, P = 0.002), and 288% (HR 3.88, 95% CI = 2.13 to 7.10, P<0.001), respectively. LVH on ECG increased the risk of ACM independently by 108% (HR 2.08, 95% CI = 1.14 to 3.81, P = 0.017). LVH either on an ECG and/or echocardiogram increased the risk of heart failure independently by 309% (HR 4.09, 95% CI = 1.34 to 12.49, P = 0.014). Conclusion: In primary care patients with hypertension, BNP seems to be an important marker predicting future CVEs, especially heart failure, as well as all-cause mortality. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis

Author

Korevaar, Tim I. M., Derakhshan, Arash, Taylor, Peter N., Meima, Marcel, Chen, Liangmiao, Bliddal, Sofie, Carty, David M., Meems, Margreet, Vaidya, Bijay, Shields, Beverley, Ghafoor, Farkhanda, Popova, Polina V., Mosso, Lorena, Oken, Emily, Suvanto, Eila, Hisada, Aya, Yoshinaga, Jun, Brown, Suzanne J., Bassols, Judith, Auvinen, Juha, Bramer, Wichor M., López-Bermejo, Abel, Dayan, Colin, Boucai, Laura, Vafeiadi, Marina, Grineva, Elena N., Tkachuck, Alexandra S., Pop, Victor J. M., Vrijkotte, Tanja G., Guxens, Mònica, Chatzi, Leda, Sunyer, Jordi, Jiménez-Zabala, Ana, Riaño, Isolina, Murcia, Mario, Lu, Xuemian, Mukhtar, Shafqat, Delles, Christian, Feldt-Rasmussen, Ulla, Nelson, Scott M., Alexander, Erik K., Chaker, Layal, Männistö, Tuija, Walsh, John P., Pearce, Elizabeth N., Steegers, Eric A. P., and Peeters, Robin P.

Published
2020
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