2,098 results on '"Pirovano, A."'
Search Results
2. A comparative analysis of an aerosol dry deposition microscale model for overhead powerlines insulators
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Luciano, Nicola, Balzarini, Alessandra, Toppetti, Anna Maria, Omodeo, Paolo, and Pirovano, Guido
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- 2024
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3. Direct in-situ insights into the asymmetric surface reconstruction of rutile TiO2 (110)
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Yuan, Wentao, Chen, Bingwei, Han, Zhong-Kang, You, Ruiyang, Jiang, Ying, Qi, Rui, Li, Guanxing, Wu, Hanglong, Ganduglia-Pirovano, Maria Veronica, and Wang, Yong
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- 2024
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4. Opening linguistic spaces in the gendered language classroom: The gender-just teacher toolkit
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Riccardo Amorati and Elena Pirovano
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inclusion ,gender pedagogy ,language education ,gender justice ,gendered language teaching ,Education (General) ,L7-991 - Abstract
Introducing gender-just linguistic practices in language education fosters the creation of a learning environment that is respectful and attentive to the diversity of language classes. In this paper, we provide an overview of existing terminology and main research studies on the thematization of gender-just language in the language classroom. We then propose a pedagogical framework in the form of a toolkit with conceptual principles and linguistic strategies and examine its practical applications. Our aim is to orient the pedagogical and linguistic choices of teachers of gendered languages in the complex task of giving linguistic visibility to gender diversity.
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- 2024
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5. Osimertinib in a patient with end-stage kidney disease not on hemodialysis
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Pirovano, Marta, Luciani, Andrea, Re Sartò, Giulia Vanessa, Bramati, Annalisa, and Cosmai, Laura
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- 2024
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6. New insights on fission of 235U induced by high energy neutrons from a new measurement at n_TOF
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A. Manna, E. Pirovano, P. Console Camprini, L. Cosentino, M. Dietz, Q. Ducasse, P. Finocchiaro, C. Le Naour, D. Mancusi, C. Massimi, A. Mengoni, R. Nolte, D. Radeck, L. Tassan-Got, N. Terranova, G. Vannini, A. Ventura, O. Aberle, V. Alcayne, S. Amaducci, J. Andrzejewski, L. Audouin, V. Babiano-Suarez, M. Bacak, M. Barbagallo, S. Bennett, E. Berthoumieux, J. Billowes, D. Bosnar, A. Brown, M. Busso, M. Caamaño, L. Caballero-Ontanaya, F. Calviño, M. Calviani, D. Cano-Ott, A. Casanovas, D.M. Castelluccio, F. Cerutti, E. Chiaveri, N. Colonna, G. Cortés, M.A. Cortés-Giraldo, S. Cristallo, L.A. Damone, P.J. Davies, M. Diakaki, C. Domingo-Pardo, R. Dressler, E. Dupont, I. Durán, Z. Eleme, B. Fernández-Domínguez, A. Ferrari, V. Furman, K. Göbel, R. Garg, A. Gawlik-Ramięga, S. Gilardoni, I.F. Gonçalves, E. González-Romero, C. Guerrero, F. Gunsing, H. Harada, S. Heinitz, J. Heyse, D.G. Jenkins, A. Junghans, F. Käppeler, Y. Kadi, A. Kimura, I. Knapová, M. Kokkoris, Y. Kopatch, M. Krtička, D. Kurtulgil, I. Ladarescu, C. Lederer-Woods, H. Leeb, J. Lerendegui-Marco, S.J. Lonsdale, D. Macina, T. Martínez, A. Masi, P. Mastinu, M. Mastromarco, E.A. Maugeri, A. Mazzone, E. Mendoza, V. Michalopoulou, P.M. Milazzo, F. Mingrone, J. Moreno-Soto, A. Musumarra, A. Negret, F. Ogállar, A. Oprea, N. Patronis, A. Pavlik, J. Perkowski, C. Petrone, L. Piersanti, I. Porras, J. Praena, J.M. Quesada, D. Ramos-Doval, T. Rauscher, R. Reifarth, D. Rochman, C. Rubbia, M. Sabaté-Gilarte, A. Saxena, P. Schillebeeckx, D. Schumann, A. Sekhar, A.G. Smith, N.V. Sosnin, P. Sprung, A. Stamatopoulos, G. Tagliente, J.L. Tain, A. Tarifeño-Saldivia, Th. Thomas, P. Torres-Sánchez, A. Tsinganis, J. Ulrich, S. Urlass, S. Valenta, V. Variale, P. Vaz, D. Vescovi, V. Vlachoudis, R. Vlastou, A. Wallner, P.J. Woods, T. Wright, and P. Žugec
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Nuclear reaction ,Neutron-induced reaction ,n_TOF ,High energy ,Fission process ,Cross section measurement ,Physics ,QC1-999 - Abstract
The 235U(n, f) reaction cross section was measured relative to neutron-proton elastic scattering for the first time in the energy region from 10 MeV to 440 MeV at the CERN n_TOF facility, extending the upper limit of the only previous measurement in the literature by more than 200 MeV. For neutron energies below 200 MeV, our results agree within one standard deviation with data in literature. Above 200 MeV, the comparison of model calculations to our data indicates the need to introduce a transient time in neutron-induced fission to allow the simultaneous description of (n, f) and (p, f) reactions.
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- 2025
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7. Sogni e visioni nella Vita nova
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Donato Pirovano
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Medioevo ,Dante Alighieri ,Vita nova ,Sogno ,Visione ,Enigma ,Archaeology ,CC1-960 ,Medieval history ,D111-203 ,Language and Literature - Abstract
La sostanza onirica è una componente importante della narrazione e della sostanza epifanica che caratterizza la Vita nova. Collocati in punti strategici della storia, tutti convergenti verso il (o dal) kérigma della morte o meglio assunzione al cielo di Beatrice, questi episodi si configurano come premonizioni e come aperture dell’orizzonte narrativo. In questo contributo sono analizzate le due, forse tre visiones in somniis, che si trovano rispettivamente nei paragrafi III, XII e XLII. Nella comune dimensione onirica e nella prefigurazione di qualcosa che avverrà tutte e tre mantengono un carattere enigmatico.
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- 2024
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8. Real‐Time Observation of Oxygen Diffusion in CGO Thin Films Using Spatially Resolved Isotope Exchange Raman Spectroscopy
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Alexander Stangl, Nicolas Nuns, Caroline Pirovano, Kosova Kreka, Francesco Chiabrera, Albert Tarancón, and Mónica Burriel
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functional thin films ,in situ characterizations ,ionic conducting oxides ,oxygen tracer diffusions ,time‐resolved kinetic coefficients ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The exploitation of advanced materials for novel energy, health, and computing applications requires deep insight and fundamental understanding of physicochemical mechanisms, such as ionic and electronic conductivity, defect formation processes, and reaction kinetics. Therefore, access to the underlying constants of the functional materials via advanced but accessible and straightforward experimental techniques is key. Herein, a novel, cheap, fast, and widely applicable approach is presented to analyze oxygen tracer diffusion in thin films with unprecedented time resolution based on the novel in situ isotope exchange Raman spectroscopy (IERS) methodology. IERS utilizes the sensitivity of micro‐Raman spectroscopy to changes in the local isotopic composition. In‐plane tracer diffusion gradients are established by partially blocking the exchange at the surface followed by an isotope exchange. The isotope exchange and diffusion processes are followed via consecutive spatial and time‐resolved in situ Raman line scans. These isotopic gradients are analyzed to obtain mass transport coefficients, with an additional time component, not accessible by conventional destructive techniques. Diffusion coefficients of gadolinium‐doped ceria (CGO) thin films are reported within the range of interest for intermediate‐temperature emerging applications and confirm the validity of the measurement procedure and extracted parameters by comparison with the finite‐element method simulations and literature results.
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- 2024
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9. RAMS analyses and tool supporting end of life decision
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Bitetti, Lorenzo, Bernard, Robert, Ratti, Beatrice, Di Giandomenico, Federico, and Pirovano, Andrea
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- 2024
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10. Post-Kidney Transplant Cancer: A Real-World Retrospective Analysis From a Single Italian Center
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Giulia Vanessa Re Sartò, Carlo Alfieri, Laura Cosmai, Emilietta Brigati, Mariarosaria Campise, Anna Regalia, Simona Verdesca, Paolo Molinari, Anna Maria Pisacreta, Marta Pirovano, Luca Nardelli, Maurizio Gallieni, and Giuseppe Castellano
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kidney transplant ,post-kidney transplant cancer ,immunosuppressive therapy ,mTOR inhibitors ,induction therapy ,Specialties of internal medicine ,RC581-951 - Abstract
We describe the epidemiology of cancer after kidney transplantation (KTx), investigating its risk factors and impact on therapeutic management and survival in KTx recipients (KTRs). The association between modification of immunosuppressive (IS) therapy after cancer and survival outcomes was analyzed. We collected data from 930 KTRs followed for 7 [1–19] years. The majority of KTRs received KTx from a deceased donor (84%). In total, 74% of patients received induction therapy with basiliximab and 26% with ATG. Maintenance therapy included steroids, calcineurin inhibitors, and mycophenolate. Patients with at least one cancer (CA+) amounted to 19%. NMSC was the most common tumor (55%). CA+ were older and had a higher BMI. Vasculitis and ADPKD were more prevalent in CA+. ATG was independently associated with CA+ and was related to earlier cancer development in survival and competing risk analyses (p = 0.01 and
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- 2024
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11. Towards a new generation of solid total-energy detectors for neutron-capture time-of-flight experiments with intense neutron beams
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Balibrea-Correa, J., Babiano-Suarez, V., Lerendegui-Marco, J., Domingo-Pardo, C., Ladarescu, I., Tarifeño-Saldivia, A., de la Fuente-Rosales, G., Gameiro, B., Zaitseva, N., Alcayne, V., Cano-Ott, D., González-Romero, E., Martínez, T., Mendoza, E., de Rada, A. Pérez, del Olmo, J. Plaza, Sánchez-Caballero, A., Casanovas, A., Calviño, F., Valenta, S., Aberle, O., Altieri, S., Amaducci, S., Andrzejewski, J., Bacak, M., Beltrami, C., Bennett, S., Bernardes, A.P., Berthoumieux, E., Beyer, R., Boromiza, M., Bosnar, D., Caamaño, M., Calviani, M., Castelluccio, D.M., Cerutti, F., Cescutti, G., Chasapoglou, S., Chiaveri, E., Colombetti, P., Colonna, N., Camprini, P. Console, Cortés, G., Cortés-Giraldo, M.A., Cosentino, L., Cristallo, S., Dellmann, S., Di Castro, M., Di Maria, S., Diakaki, M., Dietz, M., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fargier, S., Fernández, B., Fernández-Domínguez, B., Finocchiaro, P., Fiore, S., Furman, V., García-Infantes, F., Gawlik-Ramikega, A., Gervino, G., Gilardoni, S., Guerrero, C., Gunsing, F., Gustavino, C., Heyse, J., Hillman, W., Jenkins, D.G., Jericha, E., Junghans, A., Kadi, Y., Kaperoni, K., Kaur, G., Kimura, A., Knapová, I., Kokkoris, M., Kopatch, Y., Krtička, M., Kyritsis, N., Lederer-Woods, C., Lerner, G., Manna, A., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E.A., Mazzone, A., Mengoni, A., Michalopoulou, V., Milazzo, P.M., Mucciola, R., Murtas, F., Musacchio-Gonzalez, E., Musumarra, A., Negret, A., Pérez-Maroto, P., Patronis, N., Pavón-Rodríguez, J.A., Pellegriti, M.G., Perkowski, J., Petrone, C., Pirovano, E., Pomp, S., Porras, I., Praena, J., Quesada, J.M., Reifarth, R., Rochman, D., Romanets, Y., Rubbia, C., Sabaté-Gilarte, M., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A.G., Sosnin, N.V., Stamati, M.E., Sturniolo, A., Tagliente, G., Tarrío, D., Torres-Sánchez, P., Vagena, E., Variale, V., Vaz, P., Vecchio, G., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P.J., Wright, T., Zarrella, R., and Žugec, P.
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- 2025
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12. Fuel-optimal guidance using costate supervised learning with local refinement
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Evans, Adam, Armellin, Roberto, Holt, Harry, and Pirovano, Laura
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- 2025
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13. Direct in-situ insights into the asymmetric surface reconstruction of rutile TiO2 (110)
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Wentao Yuan, Bingwei Chen, Zhong-Kang Han, Ruiyang You, Ying Jiang, Rui Qi, Guanxing Li, Hanglong Wu, Maria Veronica Ganduglia-Pirovano, and Yong Wang
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Science - Abstract
Abstract The reconstruction of rutile TiO2 (110) holds significant importance as it profoundly influences the surface chemistry and catalytic properties of this widely used material in various applications, from photocatalysis to solar energy conversion. Here, we directly observe the asymmetric surface reconstruction of rutile TiO2 (110)-(1×2) with atomic-resolution using in situ spherical aberration-corrected scanning transmission electron microscopy. Density functional theory calculations were employed to complement the experimental observations. Our findings highlight the pivotal role played by repulsive electrostatic interaction among the small polarons −formed by excess electrons following the removal of neutral oxygen atoms− and the subsequent surface relaxations induced by these polarons. The emergence and disappearance of these asymmetric structures can be controlled by adjusting the oxygen partial pressure. This research provides a deeper understanding, prediction, and manipulation of the surface reconstructions of rutile TiO2 (110), holding implications for a diverse range of applications and technological advancements involving rutile-based materials.
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- 2024
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14. Design and guidance of a multi-active debris removal mission
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Wijayatunga, Minduli C., Armellin, Roberto, Holt, Harry, Pirovano, Laura, and Lidtke, Aleksander A.
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- 2023
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15. Let's Do the Math… About Creativity and Mathematical Reasoning: A Correlational Study in Primary School Children
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Vanutelli, Maria Elide, Pirovano, Giulia, Esposto, Chiara, and Lucchiari, Claudio
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Mathematics, being a very ancient discipline, is usually seen as a formal subject that must be learned for school purposes, which is very far from creativity and fun. Also, mathematical skills are often considered a talent, so students are easily divided into gifted and not gifted, with a focus on speed and accuracy rather than encouraging the process of juggling between divergent and convergent thinking. In the present paper, we aimed at investigating the relationship between mathematical reasoning and different aspects of creative thinking, such as divergent and convergent creativity, aesthetic appreciation, and humor. To do so, 146 second and third graders in a primary school in Milan have been recruited and tested with mathematical and creative tasks. Correlational analyses showed significant positive relations between flexibility and originality dimensions of creativity and mathematical performance. Results are discussed by providing a theoretical framework about the relation between mathematics and creative skills.
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- 2021
16. Unexplored microbial diversity from 2,500 food metagenomes and links with the human microbiome
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Alvarez-Ordóñez, Avelino, Alvarez, Pablo, Antonielli, Livio, Arendt, Elke, Armanini, Federica, Aubry, Aurelie, Baelum, Jacob, Barcenilla, Coral, Belanche, Alejandro, Benavent-Gil, Yaiza, Blake, Tony, Blanco-Míguez, Aitor, Bongoni, Radhika, Boyer, Mickael, Brennan, Fiona, Breselge, Samuel, Briem, Helgi, Butler, Derek, Calvete-Torre, Inés, Carballo, Omar Cristobal, Cardinal, Mireille, Carlino, Niccolò, Chervaux, Christian, Chopin, Christine, Clotaire, Natallia, Coakley, Mairead, Cobo-Díaz, José Francisco, Codd, Jim, Conroy, Stephen, Corral-Jara, Karla Fabiola, Corral-Jara, Karla-Fabiola, Cotter, Paul D., Coyne, Gerard, Creevey, Chris, Cuevas, Patricia D., Curran, Brendan, Delgado, Susana, Derde, Liesbeth, Derrien, Muriel, Ercolini, Danilo, Exposito, Ruth Gomez, López Fernández, María Mercedes, De Filippis, Francesca, Fordham, Daniel, Galy, Hubert, Gavriilidou, Asimenia, Gunnarsson, Oddur, Hanson, Buck, Hermes, Gerben, Huang, Rongcai, Huws, Sharon, Ikoyi, Israel, Jaeger, Alice, Jeffery, Ian, Jérôme, Marc, Juan, Pierre-Alexandre, Kenny, David, Kers, Annelies, Khinouche, Karim-Franck, Kirwan, Stuart, Klaassens, Eline S., Knobloch, Stephen, Kolbeinsson, Kristinn, Kolypczuk, Laetitia, Kostic, Tanja, Ledda, Fabio, Leech, John, Lehmann, Doerte, Leroi, Françoise, Lewis, Eva, Ley, Johanna, Lucic, Eva, Lynch, Kieran, Mace, Sabrina, MacLaren-Lee, Iain, Mahler de Sanchez, Lisa, Marchart, Juergen, Margolles, Abelardo, Marteinsson, Viggó Thór, Masetti, Giulia, McGovern, Fiona, McHugh, Noirin, McLoughlin, Steven, Meehan, Dara, Mølbak, Lars, Monin, Thomas, Moreno, Javier, Morgavi, Diego, Morrison, Steven, Müench, Steffen, Ramos Neves, Ana Rute, Neylon, Emma, Nyhan, Laura, O’Kelly, Rhona, O’Neil, Dominic, O’Toole, Paul, Ortiz-Chura, Abimael, Palma, Juan Manuel, Pasolli, Edoardo, Passerini, Delphine, Pastar, Milica, Pinto, Federica, Pirovano, Walter, Plans, Olga, Policht, Marion, Pop, Aurel, Pop, Bianca, Popova, Milka, Prieto, Miguel, Quijada, Narciso M., Reiss, Antje, Romero, Pedro, Ruas-Madiedo, Patricia, Rubino, Francesco, Rubio, Raul Cabrera, Ruiz, Lorena, Ryan, Angela, Ryan, Clodagh, Sabater, Carlos, Sahin, Aylin, Salaun, Cecile, Santos, Fernanda Godoy, Schneider, Carolin, Segata, Nicola, Selberherr, Evelyne, Sessitsch, Angela, Skírnisdóttir, Sigurlaug, Smidt, Hauke, Smith, Paul, Sprenger-Haussels, Markus, Tapio, Ilma, Tap, Julien, Valentino, Vincenzo, Wagner, Martin, Walsh, Aaron, Walsh, Liam, Waters, Sinead M., Willcocks, Spike, Yáñez-Ruiz, David R., Yan, Tianhai, Yap, Min, Zannini, Emanuele, Zuliani, Véronique, Punčochář, Michal, Mengoni, Claudia, Tatti, Alessia, Manghi, Paolo, Avagliano, Michele, Cabrera-Rubio, Raul, Coakley, Mairéad, Cobo-Díaz, José F., Dey, Hrituraj, Asnicar, Francesco, Fackelmann, Gloria, Heidrich, Vitor, and Rota Stabelli, Omar
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- 2024
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17. Multi-section fission ionization chamber for measurement of [formula omitted] reaction in fission tagging method
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Perkowski, J., Alcayne, V., Andrzejewski, J., Cano-Ott, D., Gawlik-Ramięga, A., Mendoza, E., Sánchez-Caballero, A., Sibbens, G., Vanleeuw, D., Aberle, O., Altieri, S., Amaducci, S., Babiano-Suarez, V., Bacak, M., Correa, J. Balibrea, Beltrami, C., Bennett, S., Bernardes, A.P., Berthoumieux, E., Beyer, R., Boromiza, M., Bosnar, D., Caamaño, M., Calviño, F., Calviani, M., Casanovas, A., Castelluccio, D.M., Cerutti, F., Cescutti, G., Chasapoglou, S., Chiaveri, E., Colombetti, P., Colonna, N., Camprini, P. Console, Cortés, G., Cortés-Giraldo, M.A., Cosentino, L., Cristallo, S., Dellmann, S., Di Castro, M., Di Maria, S., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fargier, S., Fernández, B., Fernández-Domínguez, B., Finocchiaro, P., Fiore, S., Furman, V., García-Infantes, F., Gervino, G., Gilardoni, S., González-Romero, E., Guerrero, C., Gunsing, F., Gustavino, C., Heyse, J., Hillman, W., Jenkins, D.G., Jericha, E., Junghans, A., Kadi, Y., Kaperoni, K., Kaur, G., Kimura, A., Knapová, I., Kokkoris, M., Kopatch, Y., Krtička, M., Kyritsis, N., Ladarescu, I., Lederer-Woods, C., Lerendegui-Marco, J., Lerner, G., Manna, A., Martínez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E.A., Mazzone, A., Mengoni, A., Michalopoulou, V., Milazzo, P.M., Mucciola, R., Murtas, F., Musacchio-Gonzalez, E., Musumarra, A., Negret, A., de Rada Fiol, A. Pérez, Pérez-Maroto, P., Patronis, N., Pavón-Rodríguez, J.A., Pellegriti, M.G., Petrone, C., Pirovano, E., del Olmo, J. Plaza, Pomp, S., Porras, I., Praena, J., Quesada, J.M., Reifarth, R., Rochman, D., Romanets, Y., Rubbia, C., Sabaté-Gilarte, M., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A.G., Sosnin, N.V., Stamati, M.E., Sturniolo, A., Tagliente, G., Tarifeño-Saldivia, A., Tarrío, D., Torres-Sánchez, P., Vagena, E., Valenta, S., Variale, V., Vaz, P., Vecchio, G., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P.J., Wright, T., Zarrella, R., and Žugec, P.
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- 2024
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18. Ermagora di Temno e i ‘luoghi comuni’ (T 17 Woerther)
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Pirovano, Luigi
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Cicero. Commonplace (locus communis ,κοινὸς τόπος). De inventione. Fragmentary tradition. Hermagoras of Temnos. Rhetorical argumentation. Theon. Thesis (θέσις) ,Greek language and literature. Latin language and literature ,PA ,History of the Greco-Roman World ,DE1-100 - Abstract
This paper offers a new interpretation of a passage from Theon’s progymnasmatic manual (120.13‑20 Sp.), which is traditionally included among Hermagoras of Temnos’ ‘fragments’ (T 17 W.). Based on the text preserved by Theon’s Armenian tradition and on the comparison with the parallel sources, the following conclusions can be drawn: (a) the ‘fragment’ consists of two sections, which must be considered separately; (b) while the first part can be prudently linked to Hermagoras of Temnos only, the second one is certainly attributable to him and – if correctly contextualised – may reveal some interesting details about his theory of argumentation.
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- 2024
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19. 'Verba Chrysidis morientis'. Note filologiche ed esegetiche a Eugraph. ad Ter. Andr. 282-298
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Luigi Pirovano
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eugraphius ,terence ,textual criticism ,wessner ,Literature (General) ,PN1-6790 - Abstract
Il contributo propone un’analisi filologica del commento di Eugrafio ad Andr. 281-298 (27,3-29,15 W.): vengono discussi ed interpretati i passaggi che sembrano maggiormente problematici e, dove necessario, sono suggerite delle proposte di emendazione al testo stabilito da Wessner. L’analisi dei singoli loci critici offre anche l’occasione per mettere in luce alcuni problemi teorici e pratici che non sono stati opportunamente affrontati da Wessner e con cui, pertanto, dovrà necessariamente confrontarsi il futuro editore del commentario.
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- 2023
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20. Pushing the high count rate limits of scintillation detectors for challenging neutron-capture experiments
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Balibrea-Correa, J., Lerendegui-Marco, J., Babiano-Suarez, V., Domingo-Pardo, C., Ladarescu, I., Tarifeño-Saldivia, A., Fuente-Rosales, G. de la, Alcayne, V., Cano-Ott, D., González-Romero, E., Martínez, T., Mendoza, E., de Rada, A. Pérez, del Olmo, J. Plaza, Sánchez-Caballero, A., Casanovas, A., Calviño, F., Valenta, S., Aberle, O., Altieri, S., Amaducci, S., Andrzejewski, J., Bacak, M., Beltrami, C., Bennett, S., Bernardes, A.P., Berthoumieux, E., Beyer, R., Boromiza, M., Bosnar, D., Caamaño, M., Calviani, M., Castelluccio, D.M., Cerutti, F., Cescutti, G., Chasapoglou, S., Chiaveri, E., Colombetti, P., Colonna, N., Camprini, P. Console, Cortés, G., Cortés-Giraldo, M.A., Cosentino, L., Cristallo, S., Dellmann, S., Di Castro, M., Di Maria, S., Diakaki, M., Dietz, M., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fargier, S., Fernández, B., Fernández-Domínguez, B., Finocchiaro, P., Fiore, S., Furman, V., García-Infantes, F., Gawlik-Ramikega, A., Gervino, G., Gilardoni, S., Guerrero, C., Gunsing, F., Gustavino, C., Heyse, J., Hillman, W., Jenkins, D.G., Jericha, E., Junghans, A., Kadi, Y., Kaperoni, K., Kaur, G., Kimura, A., Knapová, I., Kokkoris, M., Kopatch, Y., Krtička, M., Kyritsis, N., Lederer-Woods, C., Lerner, G., Manna, A., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E.A., Mazzone, A., Mengoni, A., Michalopoulou, V., Milazzo, P.M., Mucciola, R., Murtas, F., Musacchio-Gonzalez, E., Musumarra, A., Negret, A., Pérez-Maroto, P., Patronis, N., Pavón-Rodríguez, J.A., Pellegriti, M.G., Perkowski, J., Petrone, C., Pirovano, E., Pomp, S., Porras, I., Praena, J., Quesada, J.M., Reifarth, R., Rochman, D., Romanets, Y., Rubbia, C., Sabaté-Gilarte, M., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A.G., Sosnin, N.V., Stamati, M.E., Sturniolo, A., Tagliente, G., Tarrío, D., Torres-Sánchez, P., Vagena, E., Variale, V., Vaz, P., Vecchio, G., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P.J., Wright, T., Zarrella, R., and Žugec, P.
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- 2024
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21. Comment on “surface characterization of cerium oxide catalysts using deep learning with infrared spectroscopy of CO”
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Ganduglia-Pirovano, M. Verónica, Martínez-Arias, Arturo, Chen, Shuang, Wang, Yuemin, and Lustemberg, Pablo G.
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- 2024
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22. A bottom-up modelling chain to evaluate the impact of urban road transport policies on air quality and human health
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Piccoli, Andrea, Agresti, Valentina, Bedogni, Marco, Lonati, Giovanni, and Pirovano, Guido
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- 2024
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23. Quantitative Trait Loci Analysis of Maize Husk Characteristics Associated with Gibberella Ear Rot Resistance
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Andrea Magarini, Anna Pirovano, Martina Ghidoli, Elena Cassani, Paola Casati, and Roberto Pilu
- Subjects
maize ,Fusarium graminearum ,mycotoxin ,GWAS ,QTL ,husk ,Agriculture - Abstract
Maize (Zea mays L.) is a vital crop susceptible to Gibberella ear rot (GER), a disease caused by Fusarium graminearum, resulting in significant yield losses and mycotoxin production. This study aimed to investigate the correlation between ear characteristics and GER resistance in 74 maize inbred lines (42 with non-stiff stalks and 32 stiff stalks) adapted to the northern Italian environment. Mycotoxin analysis was performed to assess the presence of deoxynivalenol (DON) and zearalenone (ZEA). The results showed a positive correlation between the husk traits, like the husk number and husk cover, and GER resistance in both heterotic groups. A positive correlation was also found between the DON and ZEA concentrations. In addition, we conducted a genome-wide association study (GWAS) which identified novel quantitative trait loci (QTLs) associated with the husk number, husk cover, ear attitude, and infection score. These QTLs can be utilized in marker-assisted selection for breeding new GER-resistant maize varieties. Our study provides valuable insights into the genetic basis of ear traits and their relationship with GER resistance, which can contribute to an improvement in the environmental and economical sustainability of the corn growing system.
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- 2024
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24. A Segmented Total Energy Detector (sTED) optimized for (n, [formula omitted]) cross-section measurements at n_TOF EAR2
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Alcayne, V., Cano-Ott, D., Garcia, J., González-Romero, E., Martínez, T., Rada, A. Pérez de, Plaza, J., Sánchez-Caballero, A., Balibrea-Correa, J., Domingo-Pardo, C., Lerendegui-Marco, J., Casanovas, A., Calviño, F., Aberle, O., Altieri, S., Amaducci, S., Andrzejewski, J., Babiano-Suarez, V., Bacak, M., Beltrami, C., Bennett, S., Bernardes, A.P., Berthoumieux, E., Beyer, R., Boromiza, M., Bosnar, D., Caamaño, M., Calviani, M., Castelluccio, D.M., Cerutti, F., Cescutti, G., Chasapoglou, S., Chiaveri, E., Colombetti, P., Colonna, N., Camprini, P. Console, Cortés, G., Cortés-Giraldo, M.A., Cosentino, L., Dellmann, S., Di Castro, M., Di Maria, S., Diakaki, M., Dietz, M., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fargier, S., Fernández, B., Fernández-Domínguez, B., Finocchiaro, P., Fiore, S., Furman, V., García-Infantes, F., Gawlik-Ramiega, A., Gervino, G., Gilardoni, S., Guerrero, C., Gunsing, F., Gustavino, C., Heyse, J., Hillman, W., Jenkins, D.G., Jericha, E., Junghans, A., Kadi, Y., Kaperoni, K., Kaur, G., Kimura, A., Knapová, I., Kokkoris, M., Kopatch, Y., Krtička, M., Kyritsis, N., Ladarescu, I., Lederer-Woods, C., Lerner, G., Manna, A., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E.A., Mazzone, A., Mendoza, E., Mengoni, A., Michalopoulou, V., Milazzo, P.M., Mucciola, R., Murtas, F., Musacchio-Gonzalez, E., Musumarra, A., Negret, A., Pérez-Maroto, P., Patronis, N., Pavón-Rodríguez, J.A., Pellegriti, M.G., Perkowski, J., Petrone, C., Piersanti, L., Pirovano, E., Pomp, S., Porras, I., Praena, J., Quesada, J.M., Reifarth, R., Rochman, D., Romanets, Y., Rubbia, C., Sabaté-Gilarte, M., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A.G., Sosnin, N.V., Spelta, M., Stamati, M.E., Sturniolo, A., Tagliente, G., Tarifeño-Saldivia, A., Tarrío, D., Torres-Sánchez, P., Vagena, E., Valenta, S., Variale, V., Vaz, P., Vecchio, G., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P.J., Wright, T., Zarrella, R., and Žugec, P.
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- 2024
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- View/download PDF
25. How to deal with renal toxicities from immune-based combination treatments in metastatic renal cell carcinoma. A nephrological consultation for Oncologists
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Tucci, Marcello, Cosmai, Laura, Pirovano, Marta, Campisi, Ilaria, Re Sartò, Giulia Vanessa, Porta, Camillo, Gallieni, Maurizio, and Messa, Piergiorgio
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- 2024
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26. Detection and estimation of spacecraft maneuvers for catalog maintenance
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Pirovano, Laura and Armellin, Roberto
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- 2024
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27. Status report of the n_TOF facility after the 2nd CERN long shutdown period
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Patronis, N., Mengoni, A., Goula, S., Aberle, O., Alcayne, V., Altieri, S., Amaducci, S., Andrzejewski, J., Babiano-Suarez, V., Bacak, M., Balibrea Correa, J., Beltrami, C., Bennett, S., Bernardes, A. P., Berthoumieux, E., Beyer, R., Boromiza, M., Bosnar, D., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Casanovas, A., Castelluccio, D. M., Cerutti, F., Cescutti, G., Chasapoglou, S., Chiaveri, E., Colombetti, P., Colonna, N., Console Camprini, P., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Dellmann, S., Di Castro, M., Di Maria, S., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fargier, S., Fernández, B., Fernández-Domínguez, B., Finocchiaro, P., Fiore, S., García-Infantes, F., Gawlik-Ramiega, A., Gervino, G., Gilardoni, S., González-Romero, E., Guerrero, C., Gunsing, F., Gustavino, C., Heyse, J., Hillman, W., Jenkins, D. G., Jericha, E., Junghans, A., Kadi, Y., Kaperoni, K., Kaur, G., Kimura, A., Knapová, I., Kokkoris, M., Krtička, M., Kyritsis, N., Ladarescu, I., Lederer-Woods, C., Lerendegui-Marco, J., Lerner, G., Manna, A., Martínez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E. A., Mazzone, A., Mendoza, E., Michalopoulou, V., Milazzo, P. M., Mucciola, R., Murtas, F., Musacchio-Gonzalez, E., Musumarra, A., Negret, A., Pérez de Rada, A., Pérez-Maroto, P., Pavón-Rodríguez, J. A., Pellegriti, M. G., Perkowski, J., Petrone, C., Pirovano, E., Plaza del Olmo, J., Pomp, S., Porras, I., Praena, J., Quesada, J. M., Reifarth, R., Rochman, D., Romanets, Y., Rubbia, C., Sánchez-Caballero, A., Sabaté-Gilarte, M., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A. G., Sosnin, N. V., Stamati, M. E., Sturniolo, A., Tagliente, G., Tarifeño-Saldivia, A., Tarrío, D., Torres-Sánchez, P., Vagena, E., Valenta, S., Variale, V., Vaz, P., Vecchio, G., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Zarrella, R., and Zugec, P.
- Published
- 2023
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- View/download PDF
28. Genotyping by sequencing for estimating relative abundances of diatom taxa in mock communities
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Çiftçi, Ozan, Wagemaker, Cornelis A. M., Mertens, Adrienne, van Bodegom, Peter, Pirovano, Walter, and Gravendeel, Barbara
- Published
- 2023
- Full Text
- View/download PDF
29. Voices from our community: Teachers' and students' perspectives
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Curnow, Jaclyn, Gabriele, Mark, Gerges, Dolly, Pirovano, Elena, Siddell, Felix, and Weinmann, Michiko
- Published
- 2024
30. Status report of the n_TOF facility after the 2nd CERN long shutdown period
- Author
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N. Patronis, A. Mengoni, S. Goula, O. Aberle, V. Alcayne, S. Altieri, S. Amaducci, J. Andrzejewski, V. Babiano-Suarez, M. Bacak, J. Balibrea Correa, C. Beltrami, S. Bennett, A. P. Bernardes, E. Berthoumieux, R. Beyer, M. Boromiza, D. Bosnar, M. Caamaño, F. Calviño, M. Calviani, D. Cano-Ott, A. Casanovas, D. M. Castelluccio, F. Cerutti, G. Cescutti, S. Chasapoglou, E. Chiaveri, P. Colombetti, N. Colonna, P. Console Camprini, G. Cortés, M. A. Cortés-Giraldo, L. Cosentino, S. Cristallo, S. Dellmann, M. Di Castro, S. Di Maria, M. Diakaki, M. Dietz, C. Domingo-Pardo, R. Dressler, E. Dupont, I. Durán, Z. Eleme, S. Fargier, B. Fernández, B. Fernández-Domínguez, P. Finocchiaro, S. Fiore, F. García-Infantes, A. Gawlik-Ramiega, G. Gervino, S. Gilardoni, E. González-Romero, C. Guerrero, F. Gunsing, C. Gustavino, J. Heyse, W. Hillman, D. G. Jenkins, E. Jericha, A. Junghans, Y. Kadi, K. Kaperoni, G. Kaur, A. Kimura, I. Knapová, M. Kokkoris, M. Krtička, N. Kyritsis, I. Ladarescu, C. Lederer-Woods, J. Lerendegui-Marco, G. Lerner, A. Manna, T. Martínez, A. Masi, C. Massimi, P. Mastinu, M. Mastromarco, E. A. Maugeri, A. Mazzone, E. Mendoza, V. Michalopoulou, P. M. Milazzo, R. Mucciola, F. Murtas, E. Musacchio-Gonzalez, A. Musumarra, A. Negret, A. Pérez de Rada, P. Pérez-Maroto, J. A. Pavón-Rodríguez, M. G. Pellegriti, J. Perkowski, C. Petrone, E. Pirovano, J. Plaza del Olmo, S. Pomp, I. Porras, J. Praena, J. M. Quesada, R. Reifarth, D. Rochman, Y. Romanets, C. Rubbia, A. Sánchez-Caballero, M. Sabaté-Gilarte, P. Schillebeeckx, D. Schumann, A. Sekhar, A. G. Smith, N. V. Sosnin, M. E. Stamati, A. Sturniolo, G. Tagliente, A. Tarifeño-Saldivia, D. Tarrío, P. Torres-Sánchez, E. Vagena, S. Valenta, V. Variale, P. Vaz, G. Vecchio, D. Vescovi, V. Vlachoudis, R. Vlastou, A. Wallner, P. J. Woods, R. Zarrella, and P. Zugec
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Neutron time of flight ,Spallation target ,Nuclear astrophysics ,Neutron physics ,Neutron induced fission ,Neutron reactions ,Physics ,QC1-999 ,Optics. Light ,QC350-467 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
Abstract During the second long shutdown period of the CERN accelerator complex (LS2, 2019-2021), several upgrade activities took place at the n_TOF facility. The most important have been the replacement of the spallation target with a next generation nitrogen-cooled lead target. Additionally, a new experimental area, at a very short distance from the target assembly (the NEAR Station) was established. In this paper, the core commissioning actions of the new installations are described. The improvement in the n_TOF infrastructure was accompanied by several detector development projects. All these upgrade actions are discussed, focusing mostly on the future perspectives of the n_TOF facility. Furthermore, some indicative current and future measurements are briefly reported.
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- 2023
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- View/download PDF
31. A survey on cryptographic methods to secure communications for UAV traffic management
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Aissaoui, Ridwane, Deneuville, Jean-Christophe, Guerber, Christophe, and Pirovano, Alain
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- 2023
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32. CuGaO2 delafossite as a high-surface area model catalyst for Cu+-activated reactions
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Fornero, Esteban L., Murgida, Gustavo E., Bosco, Marta V., Hernández Garrido, Juan C., Aguirre, Alejo, Calaza, Florencia C., Stacchiola, Dario, Verónica Ganduglia-Pirovano, M., and Bonivardi, Adrian L.
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- 2023
- Full Text
- View/download PDF
33. Parameterised model checking of probabilistic multi-agent systems
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Pirovano, Edoardo and Lomuscio, Alessio
- Abstract
Swarm robotics has been put forward as a method of addressing a number of scenarios where scalability and robustness are desired. In order to deploy robotic swarms in safety-critical situations, it is necessary to verify their behaviour. Model checking gives a possible approach to do this; however, with traditional model checking techniques only systems of a finite size can be considered. This presents an issue for swarm systems, where the number of participants in the system is not known at design-time and may be arbitrarily large. To overcome this, parameterised model checking (PMC) techniques have been developed which enable the verification of systems where the number of participants is not known until run-time. However, protocols followed by robotic swarms are often stochastic in nature, and this cannot be modelled with current PMC techniques. This is the gap that this thesis aims to overcome. In particular, two parameterised semantics for reasoning about multi-agent systems are extended to incorporate probabilities. One of these semantics is synchronous, whilst the other is interleaved. Abstract models which overapproximate the systems being considered are constructed using counter abstraction techniques. These abstract models are used to develop parameterised verification procedures for a number of specification logics on both bounded and unbounded traces. The decision procedures presented are shown to be sound, and in some cases also complete. Further, the techniques are extended to allow modelling of situations where agents may exhibit faulty behaviour, as well as scenarios where the strategic capabilities of the participants needs to be verified. The procedures are all implemented in a novel verification toolkit called PSV (Probabilistic Swarm Verifier), built on top of the probabilistic model checker PRISM. This toolkit is used to verify three case studies from both swarm robotics and other application domains.
- Published
- 2021
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34. A redução de danos como uma ética do cuidado
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Caio Maximino and Maria Emilia Pirovano de Almeida
- Subjects
Reabilitação psicossocial ,Reabilitação da droga ,Redução de danos ,Ética do cuidado ,Drogas ,Psychology ,BF1-990 - Abstract
O presente trabalho teve como objetivo estabelecer, a partir de uma revisão narrativa da literatura, a relação da redução de danos como uma prática em ética do cuidado. O consumo de substância psicoativas é uma realidade, e que está presente nas sociedades a milênios de ano, logo muitos desses usuários de drogas não conseguem ou não desejam seguir em abstinência, para esses casos a redução de danos surge como uma alternativa de cuidado e atenção. Colocada como uma política, uma abordagem, um conjunto de práticas e alternativas, a redução de danos enxerga o sujeito além da relação droga-usuário, e não é baseada em preceitos das vertentes éticas normativas, mas pautada em preceitos da ética do cuidado, que procura respeitar os indivíduos dentro do seu contexto social, sua autonomia, e liberdade de escolha.
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- 2023
- Full Text
- View/download PDF
35. Non-Volatile Bipolar TiN/LaMnO3/Pt Memristors with Optimized Performance
- Author
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Rodriguez-Lamas, Raquel, Pla, Dolors, Pirovano, Caroline, Chaix-Pluchery, Odette, Moncasi, Carlos, Boudard, Michel, Vannier, Rose-Noëlle, Jiménez, Carmen, and Burriel, Mónica
- Published
- 2023
- Full Text
- View/download PDF
36. Genotyping by sequencing for estimating relative abundances of diatom taxa in mock communities
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Ozan Çiftçi, Cornelis A. M. Wagemaker, Adrienne Mertens, Peter van Bodegom, Walter Pirovano, and Barbara Gravendeel
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Diatoms ,GBS ,Mock communities ,Quantification ,Relative abundance ,Water quality assessment ,Ecology ,QH540-549.5 ,Evolution ,QH359-425 - Abstract
Abstract Background Diatoms are present in all waters and are highly sensitive to pollution gradients. Therefore, they are ideal bioindicators for water quality assessment. Current indices used in these applications are based on identifying diatom species and counting their abundances using traditional light microscopy. Several molecular techniques have been developed to help automate different steps of this process, but obtaining reliable estimates of diatom community composition and species abundance remains challenging. Results Here, we evaluated a recently developed quantification method based on Genotyping by Sequencing (GBS) for the first time in diatoms to estimate the relative abundances within a species complex. For this purpose, a reference database comprised of thousands of genomic DNA clusters was generated from cultures of Nitzschia palea. The sequencing reads from calibration and mock samples were mapped against this database for parallel quantification. We sequenced 25 mock diatom communities containing up to five taxa per sample in different abundances. Taxon abundances in these communities were also quantified by a diatom expert using manual counting of cells on light microscopic slides. The relative abundances of strains across mock samples were over- or under-estimated by the manual counting method, and a majority of mock samples had stronger correlations using GBS. Moreover, one previously recognized putative hybrid had the largest number of false positive detections demonstrating the limitation of the manual counting method when morphologically similar and/or phylogenetically close taxa are analyzed. Conclusions Our results suggest that GBS is a reliable method to estimate the relative abundances of the N. palea taxa analyzed in this study and outperformed traditional light microscopy in terms of accuracy. GBS provides increased taxonomic resolution compared to currently available quantitative molecular approaches, and it is more scalable in the number of species that can be analyzed in a single run. Hence, this is a significant step forward in developing automated, high-throughput molecular methods specifically designed for the quantification of [diatom] communities for freshwater quality assessments.
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- 2023
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- View/download PDF
37. The changing dynamics of languages
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Gerges, Dolly, Natoli, Angela, Pirovano, Elena, and Siddell, Felix
- Published
- 2021
38. Role of the EEG Theta Network During Software Production: A Connectivity Study
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A. Calcagno, S. Coelli, C. Amendola, I. Pirovano, R. Re, J. Medeiros, P. Carvalho, H. Madeira, and A. M. Bianchi
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EEG ,cognition ,connectivity ,software development ,mental effort ,Medical technology ,R855-855.5 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Software programming is an acquired evolutionary skill originating from consolidated cognitive functions (i.e., attentive, logical, coordination, mathematic calculation, and language comprehension), but the underlying neurophysiological processes are still not completely known. In the present study, we investigated and compared the brain activities supporting realistic programming, text and code reading tasks, analyzing Electroencephalographic (EEG) signals acquired from 11 experienced programmers. Multichannel spectral analysis and a phase-based effective connectivity study were carried out. Our results highlighted that both realistic programming and reading tasks are supported by modulations of the Theta fronto-parietal network, in which parietal areas behave as sources of information, while frontal areas behave as receivers. Nevertheless, during realistic programming, both an increase in Theta power and changes in network topology emerged, suggesting a task-related adaptation of the supporting network system. This reorganization mainly regarded the parietal area, which assumes a prominent role, increasing its hub functioning and its connectivity in the network in terms of centrality and degree.
- Published
- 2023
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- View/download PDF
39. Rehabilitation Modulates High-Order Interactions Among Large-Scale Brain Networks in Subacute Stroke
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I. Pirovano, Y. Antonacci, A. Mastropietro, C. Bara, L. Sparacino, E. Guanziroli, F. Molteni, M. Tettamanti, L. Faes, and G. Rizzo
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EEG ,functional connectivity ,granger causality ,high-order interactions ,redundancy ,rehabilitation ,Medical technology ,R855-855.5 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
The recovery of motor functions after stroke is fostered by the functional integration of large-scale brain networks, including the motor network (MN) and high-order cognitive controls networks, such as the default mode (DMN) and executive control (ECN) networks. In this paper, electroencephalography signals are used to investigate interactions among these three resting state networks (RSNs) in subacute stroke patients after motor rehabilitation. A novel metric, the O-information rate (OIR), is used to quantify the balance between redundancy and synergy in the complex high-order interactions among RSNs, as well as its causal decomposition to identify the direction of information flow. The paper also employs conditional spectral Granger causality to assess pairwise directed functional connectivity between RSNs. After rehabilitation, a synergy increase among these RSNs is found, especially driven by MN. From the pairwise description, a reduced directed functional connectivity towards MN is enhanced after treatment. Besides, inter-network connectivity changes are associated with motor recovery, for which the mediation role of ECN seems to play a relevant role, both from pairwise and high-order interactions perspective.
- Published
- 2023
- Full Text
- View/download PDF
40. Cataloguing space debris : methods for optical data association
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Pirovano, Laura and Armellin, Roberto
- Abstract
The determination of the state of resident space objects (RSOs) is fundamental to maintain a collision-free environment in space, predict space events and perform space activities. Due to the development of new sensor technologies and the ever-growing number of RSOs, the number of observations available is increasing by the day. In addition, the nature of the observations makes it very difficult to obtain a precise state of the object with only one passage of the object over the observing station. For this reason, the problem of data association becomes relevant: one has to find multiple observations of the same RSO to precisely determine its orbit. Depending on the length and precision of observations, dedicated solutions need to be developed. In this research uncertainty regions associated to the states of RSOs are semi-analytically defined through Taylor expansions, thus making not necessary point-wise sampling or dynamics simplification. This is enabled by differential algebra (DA). For very short and/or uncertain observations, a DA version of the Admissible Region (AR) from literature is defined and an efficient filter is developed for the automatic recognition of chains of observations. This filter includes a new figure of merit (FoM) for the association problem based on range intersection. When observations are long enough to allow for an initial orbit determination (IOD) solution, a new algorithm which defines the uncertainty region without a-priori constraints is developed. The main result within this framework is the definition of a clear working boundary between AR and IOD approaches depending on the optical observing strategy adopted. An advanced Monte Carlo simulation (MCS) is then employed to perform data association as intersection of the uncertainty regions defined. For longer observations where orbit determination (OD) can be performed, an optimisation routine which decouples the principal directions of the uncertainty is developed for efficient propagation and uncertainty update. Results show that the decoupling alleviates the necessity of tuning the FoM for association. Finally, the influence of different coordinate systems on uncertainty propagation is studied. It is found that not only the computation time is affected, but the absorbtion of nonlinearities in the dynamics is highly dependent on the integration variable chosen.
- Published
- 2020
41. Comparative transcriptomics reveals commonalities and differences in the genetic underpinnings of a floral dimorphism
- Author
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Giacomo Potente, Rebecca L. Stubbs, Narjes Yousefi, Walter Pirovano, Péter Szövényi, and Elena Conti
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Medicine ,Science - Abstract
Abstract Distyly, a floral dimorphism associated with heteromorphic self-incompatibility and controlled by the S-locus supergene, evolved independently multiple times. Comparative analyses of the first transcriptome atlas for the main distyly model, Primula veris, with other distylous species produced the following findings. A set of 53 constitutively expressed genes in P. veris did not include any of the housekeeping genes commonly used to normalize gene expression in qPCR experiments. The S-locus gene CYP T acquired its role in controlling style elongation via a change in expression profile. Comparison of genes differentially expressed between floral morphs revealed that brassinosteroids and auxin are the main hormones controlling style elongation in P. veris and Fagopyrum esculentum, respectively. Furthermore, shared biochemical pathways might underlie the expression of distyly in the distantly related P. veris, F. esculentum and Turnera subulata, suggesting a degree of correspondence between evolutionary convergence at phenotypic and molecular levels. Finally, we provide the first evidence supporting the previously proposed hypothesis that distyly supergenes of distantly related species evolved via the recruitment of genes related to the phytochrome-interacting factor (PIF) signaling network. To conclude, this is the first study that discovered homologous genes involved in the control of distyly in distantly related taxa.
- Published
- 2022
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- View/download PDF
42. On the Chemical Composition and Hygroscopicity of Aerosols Deposited on the Insulators of Italian Power Lines
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Irene Gini, Alessandra Balzarini, Guido Pirovano, Anna Maria Toppetti, Lucio Fialdini, Paolo Omodeo, Giovanni Pirovano, Massimo Marzinotto, Alessandro Mancini, Niccolò Losi, Amedeo Manuel Cefalì, Andrea Doldi, Ezio Bolzacchini, and Luca Ferrero
- Subjects
aerosol ,ESDD ,NSDD ,insulators ,flashover ,electricity ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The reliability of the national power grid is a key issue in modern society. Atmospheric aerosols are the main cause of the reduction in the performance of insulators and the increase in the possibility of flashovers, resulting in power line failures. Under high ambient humidity, the water-soluble compounds of atmospheric aerosols collected on the insulators’ surface can dissociate in ions and form a conductive layer, which may lead to flashover events. With a view to investigating the processes that drive these phenomena, the chemical composition of aerosol deposits on insulators in Italy was determined by ion chromatography analysis and thermos-optical and X-ray techniques. In addition, a synthetic aerosol with the same analyzed chemical composition was generated in a laboratory and deposited on PTFE filters and glass specimens allowing us to determine the deliquescence and crystallization relative humidity and the conductive effect in an aerosol exposure chamber. The results evidenced the presence of a hazardous inorganic ion layer, which generates a sharp phase transition of the aerosol deposit as a function of the ambient relative humidity; this layer poses a dangerous threat to the reliability of the power grid, increasing the probability of flashover events where the conductive layer facilitates the flow of electrical current across the insulator surface, potentially causing power outages or damage to the power lines.
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- 2023
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- View/download PDF
43. Redesigning the Drugs Distribution Network: The Case of the Italian National Healthcare Service
- Author
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Federica Asperti, Emanuela Foglia, Giovanni Pirovano, Rossella Pozzi, Tommaso Rossi, Maurizia Punginelli, and Fabrizio Schettini
- Subjects
supply chain design ,optimization ,decision support systems ,pharmaceutical distribution network ,economic assessment ,Systems engineering ,TA168 ,Technology (General) ,T1-995 - Abstract
Drug distribution performed through hospital pharmacies facilitates public expenditure savings but incurs higher social costs for patients and caregivers. The widespread presence of community pharmacies could support patient access while also improving drug distribution. The implementation of prescriptive data analyses as constrained optimization to achieve specific objectives, could be also applied with good results in the healthcare context. Assuming the perspective of the Italian National Healthcare Service, the present study, built upon existing research in this field, proposes a decision support tool that is able to define which self-administered drugs for chronic diseases should be distributed by community pharmacies, answering to critical challenges in the case of future pandemics and healthcare emergencies, while also providing suggestions for the institutional decision-making process. Moreover, the tool aids in determining the optimal setup of the drug distribution network, comparing centralized (hospital pharmacies) and decentralized (community pharmacies) approaches, as well as their economic and social implications.
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- 2024
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- View/download PDF
44. Selective Cerebrospinal Fluid Hypothermia: Bioengineering Development and In Vivo Study of an Intraventricular Cooling Device (V-COOL)
- Author
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Beretta, Simone, Versace, Alessandro, Fiore, Gianfranco, Piola, Marco, Martini, Beatrice, Bigiogera, Vittorio, Coppadoro, Lorenzo, Mariani, Jacopo, Tinti, Lorenzo, Pirovano, Silvia, Monza, Laura, Carone, Davide, Riva, Matteo, Padovano, Giada, Galbiati, Gilda, Santangelo, Francesco, Rasponi, Marco, Padelli, Francesco, Giachetti, Isabella, Aquino, Domenico, Diamanti, Susanna, Librizzi, Laura, Bruzzone, Maria Grazia, De Curtis, Marco, Giussani, Carlo, Sganzerla, Erik P., and Ferrarese, Carlo
- Published
- 2022
- Full Text
- View/download PDF
45. Direct measurement of the ionization quenching factor of nuclear recoils in germanium in the keV energy range
- Author
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A. Bonhomme, H. Bonet, C. Buck, J. Hakenmüller, G. Heusser, T. Hugle, M. Lindner, W. Maneschg, R. Nolte, T. Rink, E. Pirovano, and H. Strecker
- Subjects
Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract This article reports the measurement of the ionization quenching factor in germanium for nuclear recoil energies in the keV range. Precise knowledge of this factor in this energy range is highly relevant for coherent elastic neutrino-nucleus scattering and low mass dark matter searches with germanium-based detectors. Nuclear recoils were produced in a thin high-purity germanium target with a very low energy threshold via irradiation using monoenergetic neutron beams. The energy dependence of the ionization quenching factor was directly measured via kinematically constrained coincidences with surrounding liquid scintillator based neutron detectors. The systematic uncertainties of the measurements are discussed in detail. With measured quenching factors between 0.16 and 0.23 in the 0.4 keV $$_{nr}$$ nr to 6.3 keV $$_{nr}$$ nr energy range, the data are compatible with the Lindhard theory with a parameter k of 0.162 $$\pm \,0.004$$ ± 0.004 (stat + sys).
- Published
- 2022
- Full Text
- View/download PDF
46. Team theAntipodes: Solution methodology for GTOC11
- Author
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Armellin, Roberto, Beauregard, Laurent, Bellome, Andrea, Bernardini, Nicolò, Fossà, Alberto, Fu, Xiaoyu, Holt, Harry, Parigini, Cristina, Pirovano, Laura, and Wijayatunga, Minduli
- Published
- 2022
- Full Text
- View/download PDF
47. Making connections through languages
- Author
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Gerges, Dolly, Pirovano, Elena, and Siddell, Felix
- Published
- 2021
48. Welcome
- Author
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Curnow, Jaclyn, Gerges, Dolly, Pirovano, Elena, Siddell, Felix, and Gabriele, Mark
- Published
- 2023
49. Migraine, Brain Glucose Metabolism and the “Neuroenergetic” Hypothesis: A Scoping Review
- Author
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Del Moro, Lorenzo, Rota, Eugenia, Pirovano, Elenamaria, and Rainero, Innocenzo
- Published
- 2022
- Full Text
- View/download PDF
50. Coinage metal carbenes in heterocyclic synthesis via formation of new carbon-heteroatom bonds
- Author
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Brambilla, Elisa, Abbiati, Giorgio, Caselli, Alessandro, Pirovano, Valentina, and Rossi, Elisabetta
- Published
- 2022
- Full Text
- View/download PDF
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