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INTRODUCTION[|]The aim of this study was to investigate the potential impact of intravenous (IV) prednisolone treatment on the retinal nerve fiber layer (RNFL) in multiple sclerosis (MS) patients with optic neuritis (ON).[¤]METHODS[|]The demographic features, systemic illnesses, laboratory results, ophthalmological examination findings and RNFL measurements of 28 MS patients who had IV prednisolone treatment for ON and of 24 MS patients with ON that was not treated were retrieved and reviewed retrospectively.[¤]RESULTS[|]Of the 52 patients included in the study, 31 were women and 21 were men. The average age in the prednisolone group was 32+-7.15 years (range: 28-40 years) and it was 34+-.2 years (range: 30-42 years) in patients who did not receive treatment. The initial RNFL in the treatment group was 116.81+-5.41μm and it was 78.13+-3.94 μm at the third month, while it was 118.2+-6.07 μm initially and 80.09+-5.18 μm at the third month in the untreated group. There was no statistically significant difference between the groups in the RNLF evaluation (p>0.05).[¤]DISCUSSION AND CONCLUSION[|]Treatment with IV prednisolone had no distinct effect on RNFL.[¤]

Purpose. To assess the different check sizes of pattern visual evoked potential (PVEP) in diabetic patients without retinopathy according to HbA1c levels and diabetes duration. Methods. Fifty-eight eligible patients with type 2 diabetes mellitus and 26 age- and sex-matched healthy controls were included in the study. Only the right eye of each patient was analyzed. All of the patients underwent a comprehensive ophthalmic examination, and the PVEPs were recorded. Results. There was a statistically significant difference in P100 latency in 1-degree check size and in N135 latency in 2-degree check size between controls and patient groups which have different HbA1c levels. There were statistically significant, positive, and weak correlations with diabetes duration and P100 latency in 7-minute and 15-minute check sizes and N135 latency in 15-minute check size. Conclusions. It was showed that there were prolongations in P100 latency only in 1-degree check size and in N135 only in 2-degree check size in diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and P100 and N135 latencies in different check sizes.

Purpose. To show whether pregnancy affects the measurements of pupillary diameter and wavefront (WF) aberrations. Methods. This was a case-control study including 34 healthy pregnant women in the third trimester and age-matched 34 nonpregnant women. Only women who had no ocular abnormalities and no refractive error were included. We measured photopic and mesopic pupil diameter and WF aberrations at the third trimester and at the second postpartum month. Measurements of the right eyes were used in this study. The differences between groups were analysed by paired t-test and t-test. Results. Pregnant women’s mean photopic pupil size in the third trimester was significantly higher than in postpartum period and in control group (3.74 ± 0.77, 3.45 ± 0.53, and 3.49 ± 0.15 mm, p

INTRODUCTION[|]This study aimed to assess the multifocal electroretinography (mfERG ) findings in diabetic patients without retinopathy according to HbA1c levels and diabetes duration.[¤]METHODS[|]Sixty two eligible patients with type 2 diabetes mellitus and 30 healthy controls which were matched by age and sex were included in the study. Only the right eye of each patient was analyzed. All of the participants underwent a comprehensive ophthalmic ex amination, and the mfERG responses which were N1-P1 amplitude, N1 implicit times and P1 implicit times were calculated.[¤]RESULTS[|]The mfERG N1-P1 amplitude was significantly reduced in diabetic patients compared to controls in inner two rings. There was significantly difference between controls and stable patients' mfERG P1 implicit times in ring 2. It was found that there was negative correlation trends between diabetes duration and mfERG N1-P1 amplitude, there were negative positive correlation trends between diabetes duration and N1 implicit times and P1 implicit times in all rings. There was statistically significant negative correlation between diabetes duration and N1-P1 amplitude only in ring 5. Also, it was found that there were statistically significant positive correlations between diabetes duration and N1 implicit times in ring 1, 2 and 5. There was significantly correlation between diabetes duration and P1 implicit times only in ring 2.[¤]DISCUSSION AND CONCLUSION[|]We demonstrated that mfERG N1-P1 amplitude was reduced in inner retinal areas (ring1 and ring 2), and P1 implicit time was delayed only in ring 2 in Turkish diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and N1-P1 amplitude and N1 implicit times in some retinal areas.[¤]

Objectives: To determine the profile and clinical course of glaucoma in adult aphakic patients following complicated cataract surgery. Materials and Methods: Retrospective chart review of 22 adult aphakic patients (29 eyes) with glaucoma. Results: Mean age was 57.69±14.18 years when aphakia occurred. Mean age at time of presentation to our glaucoma clinic was 62.57±12.47 years. Mean follow-up time was 42.83±57.04 months. Changes between the first and last follow-up visits were as follows: mean intraocular pressure decreased from 26.21±13.86 mmHg to 18.14±9.63 mmHg (p=0.003); mean number of glaucoma medications used increased from 1.41±1.27 to 2.07±1.04 (p=0.005); and mean vertical cup/disc ratio increased from 0.69±0.25 to 0.78±0.24 (p=0.024). Glaucoma was managed using medications in 26 eyes (89.7%), whereas 3 eyes underwent surgical treatment. However, surgery alone was not sufficient to control intraocular pressure and additional glaucoma medications were needed. Conclusion: Prevention of glaucomatous optic neuropathy in aphakic patients is challenging both medically and surgically. Although a significant decrease in intraocular pressure can be achieved with glaucoma medications, glaucomatous disc changes may progress.