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4. Simultaneous development of a pineal tumor and an intradural spinal mass during remission of acute lymphocytic leukemia.

Author

Kudoh T, Otoi H, Suzuki N, Oda T, Katoh S, Akiba H, Hareyama M, and Chiba S

Subjects
Child, Preschool, Female, Hematopoietic Stem Cell Transplantation, Humans, Recurrence, Spinal Cord Compression etiology, Pinealoma secondary, Precursor Cell Lymphoblastic Leukemia-Lymphoma pathology, Spinal Cord Neoplasms secondary
Abstract

A small percentage of children with acute lymphocytic leukemia experience relapse in the central nervous system in spite of prophylaxis. Diffuse leptomeningeal infiltration is common but an intracranial leukemic mass or spinal cord involvement is a rare manifestation. We report a child with acute lymphocytic leukemia who simultaneously developed a pineal tumor and an intradural spinal cord mass as her first relapse. She was successfully managed by comprehensive combined treatment including peripheral blood stem cell transplantation. She remains in continuous complete remission for more than 5 years without further evidence of neurological sequelae.

Published
2000
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