Search

Your search keyword '"Otani, Koji"' showing total 762 results
Start Over Author "Otani, Koji" Language english
762 results on '"Otani, Koji"'

3. Risk factors for adverse events associated with endoscopic submucosal dissection for superficial pharyngeal cancer

Author

Ominami, Masaki, Nagami, Yasuaki, Kono, Mitsuhiro, Yamamoto, Yuki, Yokota, Chieko, Teranishi, Yuichi, Oishi, Masahiro, Manabe, Taku, Ochiai, Tadashi, Tanoue, Kojiro, Yamamura, Masafumi, Maruyama, Hirotsugu, Nadatani, Yuji, Fukunaga, Shusei, Otani, Koji, Hosomi, Shuhei, Tanaka, Fumio, Kamata, Noriko, Taira, Koichi, Sunami, Kishiko, and Fujiwara, Yasuhiro

Published
2023
Full Text
View/download PDF

14. Factors affecting the quality of life in the chronic phase of thoracolumbar osteoporotic vertebral fracture managed conservatively with a brace

Author

Inose, Hiroyuki, Kato, Tsuyoshi, Ichimura, Shoichi, Nakamura, Hiroaki, Hoshino, Masatoshi, Takahashi, Shinji, Togawa, Daisuke, Hirano, Toru, Tokuhashi, Yasuaki, Ohba, Tetsuro, Haro, Hirotaka, Tsuji, Takashi, Sato, Kimiaki, Sasao, Yutaka, Takahata, Masahiko, Otani, Koji, Momoshima, Suketaka, Hirai, Takashi, Yoshii, Toshitaka, Takahashi, Kunihiko, and Okawa, Atsushi

Published
2023
Full Text
View/download PDF

22. Effects on anorectal function of endoscopic submucosal dissection for rectal tumors involving the dentate line.

Author

Kobayashi, Yumie, Fukunaga, Shusei, Kanamori, Atsushi, Kono, Mitsuhiro, Ochiai, Tadashi, Ominami, Masaki, Otani, Koji, Hosomi, Shuhei, Tanaka, Fumio, and Fujiwara, Yasuhiro

Subjects
ANUS, RECTUM tumors, FECAL incontinence, DEFECATION, LONGITUDINAL method, ANORECTAL function tests
Abstract

Objective: Endoscopic submucosal dissection (ESD) is a specific procedure that uses an electrosurgical knife for en-bloc resectioning large tumors. However, no study has examined the effect of ESD on the defecation function of patients with rectal tumors. We aimed to investigate the potential effects caused by ESD by analyzing changes in the morphology and movement of the anorectum pre- and post-ESD. Methods: This prospective observational study included 11 patients with anorectal tumors who underwent ESD between April 2020 and February 2022. Pre-ESD assessments included anorectal manometry and defecography. Post-ESD assessments were conducted 2 months later, including anorectal manometry, defecography, and proctoscopy for ulcer and stenosis evaluation. Results: The median patient age was 73 years, including seven males and four females. Eight patients (73%) had a tumor in the lower rectum, and the extent of resection was less than 50% of the rectal lumen. Resection reached the dentate line in six cases (55%). In the patients with post-ESD mucosal defects involving the dentate line, the median of functional anal canal length significantly decreased from (3.4 cm pre-ESD to 2.8 cm post-ESD, p = 0.04). Defecography revealed one case with incomplete evacuation (<50%) and incontinence post-ESD. Interestingly, patients with pre-existing rectoceles noted resolution of lesions post-ESD. None of the patients reported daily constipation or fecal incontinence. Conclusions: While rectal ESD is unlikely to cause significant real-world defecation difficulties, alterations in rectal and anal canal morphology and function may occur if the dentate line is involved in the resection range. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

23. Radiographic Knee Osteoarthritis Is a Risk Factor for the Development of Dementia: Locomotive Syndrome and Health Outcomes in the Aizu Cohort Study.

Author

Endo, Yuji, Kobayashi, Hiroshi, Watanabe, Kazuyuki, Otani, Koji, Otoshi, Kenichi, Numazaki, Hironori, Sekiguchi, Miho, Sato, Mari, Nikaido, Takuya, Ono, Rei, Konno, Shin-ichi, and Matsumoto, Yoshihiro

Subjects
LONG-term care insurance, KNEE osteoarthritis, DISEASE risk factors, LOG-rank test, DEMENTIA
Abstract

Objective: Osteoarthritis is linked to dementia, but no longitudinal studies have established this connection. This prospective cohort study from the Locomotive Syndrome and Health Outcome in Aizu Cohort Study (LOHAS) aimed to determine if knee osteoarthritis (KOA) independently predicts dementia in adults aged 65 and above. Methods: Participants were classified by the Kellgren–Laurence scale into no/minimal KOA (grades 0 and I) and definitive KOA (grade II or higher). We analyzed dementia incidence from 2009 to 2015 using long-term care insurance data, adjusting for age, sex, vascular risks, depressive symptoms, and activity levels. Results: Out of 1089 participants (58.9% female, average age 72.5), 72.0% had definitive KOA. Dementia occurrence was significantly higher in the definitive group (8.4%) compared to the no/minimal group (3.0%) (p < 0.001). A log-rank test and Cox regression analysis confirmed these findings, showing an adjusted hazard ratio of 2.29 (confidence interval: 1.12–4.68) for dementia in those with definitive KOA. Conclusions: These results suggest that KOA is a significant risk factor for dementia, highlighting the importance of addressing contributing factors in KOA patients to potentially slow the progression of dementia. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

24. The Emerging Leaders Committee: Turning a new page for APAGE to nurture the next generation of Asia‐Pacific leaders in digestive health.

Author

Lui, Rashid N., Chan, Ting Ting, Chantarojanasiri, Tanyaporn, Chien, Mu‐Ming, Dao, Viet‐Hang, Devi, Jalpa, Huang, Daniel Q., Jin, Eun‐Hyo, Khurelbaatar, Tsevelnorov, Nabi, Zaheer, Otani, Koji, Panlilio, Mara Teresa T., Park, Sang Hyoung, Pribadi, Rabbinu Rangga, Qiao, Yuqi, Siah, Kewin, Sonthalia, Nikhil, Tran, Quang Trung, Xiao, Yinglian, and Raja Ali, Raja Affendi

Subjects
MEDICAL personnel, INFLAMMATORY bowel diseases, COVID-19 pandemic, ENDOSCOPIC retrograde cholangiopancreatography, PUBLIC health infrastructure, CLINICAL medicine, JOURNAL writing, PERIODICAL subscriptions
Abstract

The article discusses the establishment of the Emerging Leaders Committee (ELC) by the Asian Pacific Association of Gastroenterology (APAGE) to support and develop emerging leaders in digestive health from the Asia-Pacific region. The ELC aims to create a community of young healthcare professionals and provide mentorship, networking opportunities, and leadership development. The committee has established focus groups and plans to organize webinars, forums, and collaborations with the Journal of Gastroenterology and Hepatology (JGH) to enhance education, research, and publication opportunities. The ELC also aims to foster international engagement and strengthen ties with other young chapters of global organizations. [Extracted from the article]

Published
2024
Full Text
View/download PDF

28. Risk factors for subsequent vertebral fracture after acute osteoporotic vertebral fractures

Author

Inose, Hiroyuki, Kato, Tsuyoshi, Ichimura, Shoichi, Nakamura, Hiroaki, Hoshino, Masatoshi, Togawa, Daisuke, Hirano, Toru, Tokuhashi, Yasuaki, Ohba, Tetsuro, Haro, Hirotaka, Tsuji, Takashi, Sato, Kimiaki, Sasao, Yutaka, Takahata, Masahiko, Otani, Koji, Momoshima, Suketaka, Takahashi, Kunihiko, Yuasa, Masato, Hirai, Takashi, Yoshii, Toshitaka, and Okawa, Atsushi

Published
2021
Full Text
View/download PDF

30. Gastrointestinal endoscopic practice during COVID-19 pandemic: a multi-institutional survey

Author

Maruyama Hirotsugu, Hosomi Shuhei, Nebiki Hiroko, Fukuda Takashi, Nakagawa Koichiro, Okazaki Hirotoshi, Yamagami Hirokazu, Hara Junichi, Tanigawa Tetsuya, Machida Hirohisa, Aomatsu Kazuki, Watanabe Yoshihisa, Sato Hiroshi, Uno Hironori, Takaishi Osamu, Nomura Tsutomu, Ochi Masahiro, Oshitani Nobuhide, Adachi Kenji, Higashimori Akira, Ominami Masaki, Nadatani Yuji, Fukunaga Shusei, Otani Koji, Tanaka Fumio, Kamata Noriko, Nagami Yasuaki, Taira Koichi, Watanabe Toshio, and Fujiwara Yasuhiro

Subjects
covid-19, endoscopy, sars-cov-2, survey, personal protective equipment, Internal medicine, RC31-1245
Abstract

Introduction. An on-going coronavirus disease 2019 (COVID-19) has become a challenge all over the world. Since an endoscopy unit and its staff are at potentially high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, we conducted a survey for the management of the gastrointestinal endoscopic practice, personal protective equipment (PPE), and risk assessment for COVID-19 during the pandemic at multiple facilities.

Published
2021
Full Text
View/download PDF

35. Predictors for quality of life improvement after acute osteoporotic vertebral fracture: results of post hoc analysis of a prospective randomized study

Author

Inose, Hiroyuki, Kato, Tsuyoshi, Nakamura, Hiroaki, Hoshino, Masatoshi, Togawa, Daisuke, Hirano, Toru, Tokuhashi, Yasuaki, Ohba, Tetsuro, Haro, Hirotaka, Tsuji, Takashi, Sato, Kimiaki, Sasao, Yutaka, Takahata, Masahiko, Otani, Koji, Momoshima, Suketaka, Takahashi, Kunihiko, Yuasa, Masato, Hirai, Takashi, Yoshii, Toshitaka, and Okawa, Atsushi

Published
2021
Full Text
View/download PDF

36. Neutrophil extracellular trap formation and its implications in nonsteroidal anti‐inflammatory drug‐induced small intestinal injury.

Author

Moriyama, Eiji, Nadatani, Yuji, Higashimori, Akira, Otani, Koji, Ominami, Masaki, Fukunaga, Shusei, Hosomi, Shuhei, Tanaka, Fumio, Taira, Koichi, Fujiwara, Yasuhiro, and Watanabe, Toshio

Subjects
INTESTINAL injuries, ARGININE deiminase, NEUTROPHILS, DRUG side effects, CELL-free DNA, INTESTINAL tumors
Abstract

Background and Aim: Nonsteroidal anti‐inflammatory drugs (NSAIDs) damage the small intestine via neutrophil infiltration driven by the mucosal invasion of enterobacteria. The antimicrobial function of neutrophils is partially dependent on neutrophil extracellular traps (NETs). Excessive NET formation has been associated with several inflammatory diseases. Here, we aimed to investigate the role of NETs in NSAID‐induced small intestinal damage using human samples and an experimental mouse model. Methods: Human small intestine specimens were obtained from NSAID users during double‐balloon enteroscopy. Wild‐type, protein arginine deiminase 4 (PAD4) knockout, and antibiotic‐treated mice were administered indomethacin to induce small intestinal injury. The expression of NET‐associated proteins, including PAD4, citrullinated histone H3 (CitH3), cell‐free DNA, and myeloperoxidase (MPO), was evaluated. Results: The double‐positive stained area with CitH3 and MPO, which is specific for neutrophil‐derived extracellular traps, was significantly high in the injured small intestinal mucosa of NSAID users. In a mouse model, small intestinal damage developed at 6 h after indomethacin administration, accompanied by increased mRNA levels of interleukin‐1β and keratinocyte chemoattractant and elevated NET‐associated protein levels of PAD4, CitH3, and MPO in small intestine and serum levels of cell‐free DNA. Both genetic deletion and pharmacological inhibition of PAD4 attenuated this damage by reducing the mRNA expression of inflammatory cytokines and NET‐associated proteins. Furthermore, mice pretreated with antibiotics showed resistance to indomethacin‐induced small intestinal damage, with less NET formation. Conclusion: These results suggest that NETs aggravate NSAID‐induced small intestinal injury. Therefore, NET inhibition could be a potential treatment for NSAID‐induced small intestinal injury. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

37. Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis—Five-Year Results of Selective Decompression of Symptomatic Levels.

Author

Watanabe, Kazuyuki, Otani, Koji, Nikaido, Takuya, Kato, Kinshi, Kobayashi, Hiroshi, Yabuki, Shoji, Konno, Shin-ichi, and Matsumoto, Yoshihiro

Subjects
SPINAL stenosis, SURGICAL decompression, LEG pain, SCIATICA, ASYMPTOMATIC patients, MAGNETIC resonance imaging, INTERMITTENT claudication
Abstract

Background: In the diagnosis of lumbar spinal stenosis (LSS), finding stenosis with magnetic resonance imaging (MRI) does not always correlate with symptoms such as sciatica or intermittent claudication. We perform decompression surgery only for cases where the levels diagnosed from neurological findings are symptomatic, even if multiple stenoses are observed on MRI. The objective of this study was to examine the time course of asymptomatic stenosis in patients with LSS after they underwent decompression surgery for symptomatic stenosis. Materials and Methods: The participants in this study comprised 137 LSS patients who underwent single-level L4–5 decompression surgery from 2003 to 2013. The dural sac cross-sectional area at the L3–4 disc level was calculated based on preoperative MRI. A cross-sectional area less than 50 mm2 was defined as stenosis. The patients were grouped, according to additional spinal stenosis at the L3–4 level, into a double group (16 cases) with L3–4 stenosis, and a single group (121 cases) without L3–4 stenosis. Incidences of new-onset symptoms originating from L3–4 and additional L3–4-level surgery were examined. Results: Five years after surgery, 98 cases (72%) completed follow-up. During follow-up, 2 of 12 patients in the double group (16.7%) and 9 of 86 patients in the single group (10.5%) presented with new-onset symptoms originating from L3–4, showing no significant difference between groups. Additional L3–4 surgery was performed for one patient (8.3%) in the double group and three patients (3.5%) in the single group; again, no significant difference was shown. Conclusion: Patients with asymptomatic L3–4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3–4-level surgery within 5 years after surgery when compared to patients without preoperative L3–4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

42. Association Between the Discrepancy in Self-Reported and Performance-Based Physical Functioning Levels and Risk of Future Falls Among Community-Dwelling Older Adults: The Locomotive Syndrome and Health Outcomes in Aizu Cohort Study (LOHAS)

Author

Kamitani, Tsukasa, Yamamoto, Yosuke, Fukuma, Shingo, Ikenoue, Tatsuyoshi, Kimachi, Miho, Shimizu, Sayaka, Yamamoto, Shungo, Otani, Koji, Sekiguchi, Miho, Onishi, Yoshihiro, Takegami, Misa, Ono, Rei, Yamazaki, Shin, Konno, Shinichi, Kikuchi, Shinichi, and Fukuhara, Shunichi

Published
2019
Full Text
View/download PDF

44. Correlation between anxiety and decreased quality of life in patients with non‐esophageal eosinophilic gastrointestinal diseases.

Author

Tanaka, Fumio, Kanamori, Atsushi, Sawada, Akinari, Ominami, Masaki, Nadatani, Yuji, Fukunaga, Shusei, Otani, Koji, Hosomi, Shuhei, Kamata, Noriko, Nagami, Yasuaki, Taira, Koichi, and Fujiwara, Yasuhiro

Subjects
GASTROINTESTINAL diseases, ANXIETY, QUALITY of life, MENTAL depression, URBAN hospitals
Abstract

Background and Aim: Mental status such as anxiety and depression in patients with non‐esophageal eosinophilic gastrointestinal diseases (non‐EoE EGIDs) has not been studied. The aim of this study was to evaluate whether patients with non‐EoE EGIDs had mental disorders and decreased mental‐health‐related quality of life (QOL) similar to those in patients with disorders of gut–brain interaction (DGBI). Methods: We enrolled patients with non‐EoE EGIDs and DGBI visiting the Osaka Metropolitan University Hospital, and the measures listed below were compared between the groups. We collected data using the following questionnaires: hospital anxiety and depression scale, and short form (SF)‐8 including mental component summary (MCS)‐8. Results: We evaluated 21 and 17 patients with non‐EoE EGIDs and DGBI, respectively. The anxiety score was not significantly different between the groups. The proportion of patients with possible anxiety was not significantly different between the groups (19.0% vs 33.3%). These results show that patients with non‐EoE EGIDs had anxiety that might be equivalent to that of patients with DGBI. The depression score and proportion of patients with possible depression in the non‐EoE EGID group tended to be lower than those in the DGBI group. MCS‐8 scores were not significantly different between the non‐EoE EGID and DGBI groups, which might imply an equivalent decrease in mental‐health‐related QOL in both groups of patients. In patients with non‐EoE EGIDs, the anxiety score had a significant inverse association with the MCS‐8 score. Conclusions: Patients with non‐EoE EGIDs may have anxiety that correlates with decreased mental‐health‐related QOL. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results