28 results on '"Ortiz, Gisela"'
Search Results
2. Lipase from Rhizomucor miehei onto home-made hydrophobic polymers: Stable and efficient biocatalysts
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Fé, Luana X.S.G.M., dos Santos, Michelle M., Costa, Carolina S., Pinto, Martina C.C., de Oliveira, Renata A., Cipolatti, Eliane P., Pinto, José Carlos, Langone, Marta A.P., Dellamora-Ortiz, Gisela M., and Manoel, Evelin A.
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- 2024
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3. Fish oil attenuates persistent inflammatory pain in rats through modulation of TNF-α and resolvins
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Lobo, Bianca W.P., Lima, Cleverton Kleiton F., Teixeira, Monique S., Silva, Natália L.C., Takiya, Christina M., Ramos, Mônica F.S., Miranda, Ana Luísa P., and Dellamora-Ortiz, Gisela Maria
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- 2016
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4. Development and validation of a method for allantoin determination in liposomes and pharmaceutical formulations
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Braga, Raquel Rennó, Sales, Juliana, Marins, Rita de Cassia Elias Estrela, Ortiz, Gisela Maria Dellamora, and Garcia, Sheila
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- 2012
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5. Enzymes in the time of COVID‐19: An overview about the effects in the human body, enzyme market, and perspectives for new drugs.
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Fé, Luana Xavier Soares Gomes Moura, Cipolatti, Eliane Pereira, Pinto, Martina Costa Cerqueira, Branco, Suema, Nogueira, Fábio César Sousa, Ortiz, Gisela Maria Dellamora, Pinheiro, Anderson de Sá, and Manoel, Evelin Andrade
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GLYCERALDEHYDEPHOSPHATE dehydrogenase ,HUMAN body ,ENZYMES ,VIRUS-induced enzymes ,COVID-19 ,AMYLASES ,LACTATE dehydrogenase - Abstract
The rising pandemic caused by a coronavirus, resulted in a scientific quest to discover some effective treatments against its etiologic agent, the severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2). This research represented a significant scientific landmark and resulted in many medical advances. However, efforts to understand the viral mechanism of action and how the human body machinery is subverted during the infection are still ongoing. Herein, we contributed to this field with this compilation of the roles of both viral and human enzymes in the context of SARS‐CoV‐2 infection. In this sense, this overview reports that proteases are vital for the infection to take place: from SARS‐CoV‐2 perspective, the main protease (Mpro) and papain‐like protease (PLpro) are highlighted; from the human body, angiotensin‐converting enzyme‐2, transmembrane serine protease‐2, and cathepsins (CatB/L) are pointed out. In addition, the influence of the virus on other enzymes is reported as the JAK/STAT pathway and the levels of lipase, enzymes from the cholesterol metabolism pathway, amylase, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, and glyceraldehyde 3‐phosphate dehydrogenase are also be disturbed in SARS‐CoV‐2 infection. Finally, this paper discusses the importance of detailed enzymatic studies for future treatments against SARS‐CoV‐2, and how some issues related to the syndrome treatment can create opportunities in the biotechnological market of enzymes and the development of new drugs. [ABSTRACT FROM AUTHOR]
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- 2022
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6. Stabilization of different alcohol oxidases via immobilization and post immobilization techniques
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Lopez-Gallego, Fernando, Betancor, Lorena, Hidalgo, Aurelio, Dellamora-Ortiz, Gisela, Mateo, Cesar, Fernández-Lafuente, Roberto, and Guisán, Jose M.
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- 2007
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7. A new sunscreen of the cinnamate class: Synthesis and enzymatic hydrolysis evaluation of glyceryl esters of p-methoxycinnamic acid
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de Freitas, Zaida Maria Faria, Santos, Elisabete Pereira dos, Rocha, João Ferreira da, Dellamora-Ortiz, Gisela Maria, and Gonçalves, José Carlos Saraiva
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- 2005
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8. Enzyme stabilization by glutaraldehyde crosslinking of adsorbed proteins on aminated supports
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López-Gallego, Fernando, Betancor, Lorena, Mateo, Cesar, Hidalgo, Aurelio, Alonso-Morales, Noelia, Dellamora-Ortiz, Gisela, Guisán, Jose M., and Fernández-Lafuente, Roberto
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- 2005
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9. 328 - Anterior and Lateral Lumbar Instrumentation
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Murray-Ortiz, Gisela, Park, Michael S., and Uribe, Juan S.
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- 2017
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10. Microencapsulation of fish oil by casein-pectin complexes and gum arabic microparticles: oxidative stabilisation.
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Vaucher, Arianne Cunha dos Santos, Dias, Patrícia C. M., Coimbra, Pablo T., Costa, Irina dos Santos Miranda, Marreto, Ricardo Neves, Dellamora-Ortiz, Gisela Maria, De Freitas, Osvaldo, and Ramos, Mônica F. S.
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MALTODEXTRIN ,FISH oils ,GUM arabic ,MICROENCAPSULATION ,SPRAY drying ,SCANNING electron microscopy - Abstract
This study was aimed to microencapsulate fish oil (FO) in two biocompatible polymeric blends: gum arabic (GA)-maltodextrin (MD) and casein-pectin (CP)-MD. GA-MD microparticles and CP-MD microparticles were produced by spray-drying and complex coacervation and spray-drying, respectively. Encapsulation efficiency, particle size, moisture content, oxidative stability, and morphological properties were analysed. Encapsulation efficiencies of 51.2–56.8% (w/v) for GA and 64.7–67.9% (w/v) for CP preparations were found. GA particle sizes varied from 2 to 100 μm and from 2 to 120 μm for CP microparticles. Spherical forms with depressions in the topography of both systems were evidenced by scanning electron microscopy. Confocal microscopy evidenced surface oil on GA microparticles, corroborating encapsulation efficiency. CP was more efficient than GA to reduce oxidation, with maximum peroxide values (PVs) of 17.40 mmol/kg oil after 28 d at 40 °C/75% relative humidity (RH). Thus, CP is a promising biopolymeric blend for encapsulation of FO that provides protection against lipid oxidation. [ABSTRACT FROM AUTHOR]
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- 2019
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11. Rapid and efficient synthesis of five- to eight-membered cyclic aminals under ultrasound irradiation
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Ramírez, María A., Ortiz, Gisela, Levín, Gustavo, McCormack, Walter, Blanco, María M., Perillo, Isabel A., and Salerno, Alejandra
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- 2014
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12. A novel alkylation procedure using MW irradiation for the synthesis of 1,2,3-trisubstituted 1,4,5,6,7,8-hexahydro-1,3-diazocinium salts from their corresponding 1,2-diaryldiazocines
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Ramírez, María A., Ortiz, Gisela M., Salerno, Alejandra, Perillo, Isabel A., and Blanco, María M.
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- 2012
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13. Evaluation of the antioxidant and phototoxic potentials of Bauhinia microstachya var. massambabensis Vaz leaf extracts
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Mansur, Maria Cristina.P.P.R., Leitão, Susana G., Lima, Luis M.T.R., Ricci-Júnior, Eduardo, Souza, Gabriela R. de, Barbi, Nancy dos S., Martins, Tathiana S., Dellamora Ortiz, Gisela M., Leo, Rodrigo R. T., Vieira, Ricardo C., Leitão, Gilda G., and Santos, Elizabete P.
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Bauhinia ,Antioxidantes ,Farmacia ,Flavonoides ,Extractos Vegetales - Abstract
Four different leaf extracts of B. microstachya var. massambabensis were studied to evaluate their antioxidant capacity by using three in vitro methods, with Ginkgo biloba and Trolox® as the standards. With the DPPH and ABTS·+ methods, the antioxidant activity of the extracts was in the following order, from maximum to minimum: AcEt > WAc > raw EtOH > EtOH CA > EGb, while with the ORAC method, it was as follows: EtOH CA > raw EtOH > AcEt > WAc > EGb. Phototoxic analysis was performed in yeast cultures of Saccharomyces cerevisiae. From the ethyl acetate extract, 2 flavonoids kaempferol-3-O-rhamnoside and astragalin-2”,6”-O-digallate were isolated and identified by HPLC and 1H- and 13C-NMR; to our knowledge, this is the first report of the occurrence of astragalin-2”,6”-O-digallate in the Bauhinia genus., Colegio de Farmacéuticos de la Provincia de Buenos Aires
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- 2012
14. New synthetic routes for N-substituted 1,n-diamines. II. Synthesis of selectively N-substituted tetra- and pentamethylenediamines from ω-alkanoic acid derivatives
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Ramírez, María A., Corona, María V., Ortiz, Gisela, Salerno, Alejandra, Perillo, Isabel A., and Blanco, María M.
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- 2011
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15. Contributors
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Aarabi, Bizhan, Abbott, Rick, Abd-El-Barr, Muhammad M., Abel, Taylor J., Abruzzo, Todd A., Acar, Feridun, Achey, Rebecca L., Ackerman, Paul D., Adams, Hadie, Adappa, Nithin D., Adelson, P. David, Aguirre-Padilla, David H., Ahmed, Raheel, Ahn, Edward S., Ailon, Tamir T., Ain, Michael C., Aisiku, Imoigele P., Alaraj, Ali, AlBakry, Amr, Albuquerque, Felipe C., Alexander, Brian M., Alexander, Michael J., Alexandrov, Andrei V., Ali, Zarina S., Al-Khalili, Kenan, Al-Mefty, Ossama, Almefty, Kaith K., Almefty, Rami, Alterman, Ron L., Amenta, Peter S., Ames, Christopher P., Amin-Hanjani, Sepideh, Ammirati, Mario, Andaluz, Norberto, Anderson, Richard C.E., Andrade, Pablo, Angevine, Peter D., Ansari, Shaheryar F., Ares, William J., Arle, Jeffrey E., Armonda, Rocco A., Arnaout, Omar, Arnaud, Eric, Arnold, Paul M., Assina, Rachid, Aszmann, Oskar C., Attenello, Frank J., III, Badhiwala, Jetan H., Baehring, Joachim M., Baggott, Christopher D., Bagić, Anto, Bahgat, Diaa, Bailes, Julian E., Bain, Mark, Ball, Perry A., Baltuch, Gordon H., Baraban, Scott C., Barak, Tanyeri, Barani, Igor J., Barbagallo, Giuseppe M.V., Barbaro, Nicholas M., Barker, Frederick G., II, Barnett, Gene H., Barone, Constance M., Barrow, Daniel Louis, Bassani, Luigi, Batchelor, Tracy T., Batista, Nuno, Batjer, H. Hunt, Baum, Griffin R., Beattie, Michael S., Beaumont, Andrew, Becker, Danielle A., Beckman, Joshua M., Becske, Tibor, Bederson, Joshua B., Beisse, Rudolf W., Bekelis, Kimon, Bell, Randy S., Belzberg, Allan J., Benarroch, Eduardo E., Bendok, Bernard R., Benet, Arnau, Berenstein, Alejandro, Berger, Mitchel S., Bergsneider, Marvin, Bertalanffy, Helmut, Bhatnagar, Saurabha, Bi, Wenya Linda, Birk, Harjus Singh, Bishop, Allen T., Blakeley, Jaishri O., Blomstedt, Patric, Bolinger, Bryan D., Bonney, Phillip A., Boomsaad, Zackary E., Boop, Frederick A., Borg, Nicholas, Boszczyk, Bronek M., Botelho, Ricardo Vieira, Bou-Haidar, Pascal, Bowyer, Susan M., Bragg, Taryn McFadden, Brem, Henry, Brem, Steven, Bresnahan, Jacqueline C., Brinkmann, Benjamin H., Brînzeu, Andrei, Britz, Gavin W., Brockmeyer, Douglas L., Browd, Samuel R., Brown, Desmond A., Brown, Martin, Brown, Matthew T., Brown, Robert D., Jr., Bruce, Jeffrey N., Brunstrom-Hernandez, Janice E., Brunswick, Andrew, Buell, Thomas J., Bullock, M. Ross, Burchiel, Kim J., Burrows, Anthony M., Bydon, Mohamad, Byrne, Richard W., Cahill, Daniel P., Cahill, Kevin S., Calcagnotto, Maria Elisa, Caplan, Justin M., Cascino, Gregory D., Castinetti, Frederic, Cawley, C. Michael, Cernak, Ibolja, Certo, Francesco, Cetas, Justin S., Chan, Michael D., Chanda, Amitabha, Chang, Edward F., Chang, Steven D., Charbel, Fady T., Chari, Aswin, Chaudhary, Navjot, Chauvel, Patrick, Chen, Kevin S., Chen, Liang, Cheng, Joseph S., Cheng, Yuwei, Cheung, Kenneth M.C., Chiocca, E. Antonio, Cho, Catherine, Chou, Dean, Choudhri, Omar, Christian, Cindy W., Claassen, Jan, Claus, Elizabeth B., Cleary, Daniel R., Cohen, Alan R., Collins, John, Connolly, E. Sander, Jr., Cooke, Jonathon, Coppens, Jeroen R., Corcos, Daniel M., Coric, Domagoj, Cornips, Erwin M.J., Cosgrove, G. Rees, Couldwell, William T., Crino, Peter B., Crofton, Andrew, Cullen, D. Kacy, Curry, Brian P., da Silva, Erasmo Barros, Jr., Dailey, Andrew T., Dallapiazza, Robert F., Dalyai, Richard Tyler, Danan, Deepa, Daniels, David J., Darsaut, Tim E., Dash, Alexander, Dashnaw, Matthew L., David, Carlos A., David, David J., Day, Arthur L., De la Garza-Ramos, Rafael, De Salles, Antonio A.F., Dea, Nicolas, Decker, Matthew, Del Brutto, Oscar H., Delman, Bradley N., DeLong, Mahlon R., DeMonte, Franco, Deogaonkar, Milind, Desai, Arati, Desai, Virendra R., Di Rocco, Federico, Diebo, Bassel G., DiLuna, Michael L., DiMeco, Francesco, Dirks, Peter, Dlouhy, Brian J., Doshi, Amish H., Drake, James M., Drofa, Alexander, Ducruet, Andrew F., Duffau, Hugues, Duhaime, Ann-Christine, Dumont, Aaron S., Dunn, Gavin P., Dunn, Ian F., Dusick, Joshua R., Eberwine, James H., Eboli, Paula, Eckardt, Gerald W., Edwards, Michael S.B., Edwards, Richard J., Elder, J. Bradley, Elhammady, Mohamed Samy A., Elias, W. Jeffrey, Ellis, Jason A., Elmadhoun, Tarek M.I., Emch, Todd M., Emerson, Samuel, Ene, Chibawanye, Englot, Dario J., Eskandari, Ramin, Ewend, Matthew G., Fakurnejad, Shayan, Falavigna, Asdrubal, Fan, Yi, Farina, Dario, Farrell, Christopher J., Fehlings, Michael G., Feigin, Valery, Feldman, Eva L., Feldstein, Neil, Feng, James E., Fenno, Lief E., Ferguson, Sherise D., de Oliveira, Matheus Fernandes, Figueroa, Javier M., Figueroa, Juan J., Filler, Aaron G., Findlay, J. Max, Finn, Michael A., Finnell, Richard H., Fisher, Charles G., Flamm, Eugene S., Flemming, Kelly D., Flores-Sarnat, Laura, Follett, Kenneth A., Foreman, Paul M., Foster, Kimberly A., Freeze, Benjamin S., Fried, Itzhak, Friedlander, Robert M., Fry, Donald E., Fu, Kai-Ming Gregory, Fulkerson, Daniel H., Fuller, Gregory N., Fusco, Matthew R., Galvan, Adriana, Gandhoke, Gurpreet S., Garcia, Hector H., Gardner, Paul A., Garton, Hugh, Gavin, Cormac G., Gaynor, Brandon G., George, Timothy M., Georgoulis, George, Gerard, Carter S., Gerke, Luke, Gerosa, Massimo, Gerszten, Kristina, Gerszten, Peter C., Ghatan, Saadi, Ghobrial, George M., Ghosh, Chaitali, Giacobbe, Peter, Gianaris, Thomas J., Giglio, Pierre, Gilad, Ronit, Gjedde, Albert H., Göçmen, Selçuk, Godzik, Jakub, Goel, Atul, Gogela, Steven L., Gokaslan, Ziya L., Goldstein, Hannah E., Golfinos, John G., Gologorsky, Yakov, Golshani, Kiarash, Gonzalez, Nestor R., Gonzalez-Martinez, Jorge, Goodden, John, Goodman, J. Clay, Goodrich, James Tait, Goodwin, C. Rory, Gordon, David S., Gorgulho, Alessandra, Goumnerova, Liliana C., Goyal, Anshit, Grady, M. Sean, Grafman, Jordan H., Gragnaniello, Cristian, Grande, Andrew W., Grant, Gerald A., Grant, Ryan A., Griessenauer, Christoph J., Groff, Michael W., Gross, Robert E., Grossberg, Jonathan A., Grossman, Aaron W., Grossman, Rachel, Groves, Mari L., Gruenberg, Marcelo Fernando, Gunel, Jennifer Moliterno, Günel, Murat, Gupta, Nalin, Haddad, Georges F., Haglund, Michael M., Haines, Stephen J., Haldeman, Clayton L., Halvorson, Kyle G., Hamberger, Marla J., Haq, Ihtsham U., Haranhalli, Neil, Harbaugh, Robert E., Hariz, Marwan, Harrigan, Mark R., Harrop, James S., Härtl, Roger, Harwell, Daniel M., Hasan, David M., Hashemiyoon, Rowshanak, Hassaneen, Wael, Hawryluk, Gregory W.J., Hayward, Richard David, He, Lucy, Healy, Andrew T., Heary, Robert F., Heimberger, Amy B., Prof. Dr. med., Heini, Heinricher, Mary M., Henrikson, Karl J., Heros, Roberto C., Herrup, Karl, Hervey-Jumper, Shawn, Heuer, Gregory G., Higuchi, Yoshinori, Gilmer, Holly S., Hirsch, Lawrence J., Hoffer, S. Alan, Holland, Eric, Holland, Ryan, Hongo, Kazuhiro, Horisawa, Shiro, Horner, Philip J., Houseman, Clifford M., Howard, Matthew A., III, Hsueh, Brian, Huang, Judy, Huang, Michael C., Huang, Raymond Y., Hudgins, Eric, Hunt, Matthew A., Hurlbert, R. John, Hutchinson, Peter J., Huttner, Anita, Hwang, Steven W., Iliff, Jeffrey J., Ingram, Susan L., Isaias, Ioannis U., Iskandar, Bermans J., Iyer, Aditya K., Jacob, R. Patrick, Jada, Ajit, Jadhav, Ashutosh P., Jaffer, Hayder, Jakacki, Regina I., Jallo, George I., Jallo, Jack I., Jamil, Osama, Jane, John A., Jr., Jane, John A., Sr., Janigro, Damir, Jankowitz, Brian T., Jea, Andrew H., Jeelani, Owase, Jehi, Lara, Jellinger, Kurt A., Jho, Diana, Jimenez, David F., Jo, Jasmin T., Johanson, Conrad E., Johnson, Luke A., Jones, Adrian C., Jones, Kristen E., Joseph, Jacob R., Jovin, Tudor G., Kalani, M. Yashar S., Kalanithi, Paul S.A., Kalfas, Iain H., Kalnins, Aleksandrs Uldis, Kalra, Ricky Raj Singh, Kamath, Ashwin A., Kang, Daniel G., Kang, James D., Kanter, Adam S., Kaplitt, Michael G., Karimi, Reza J., Kasliwal, Manish K., Kawasaki, Hiroto, Kelleher, John Paul, Kellner, Christopher P., Kemeny, Andras A., Kennedy, Benjamin C., Kestle, John R.W., Khan, Imad Saeed, Khan, Nadia, Khurana, Vini G., Kim, Dong Gyu, Kim, Dong H., Kim, Irene, Kim, Jin Wook, Kim, Louis J., Kim, Paul K., Kim, Thomas Aquinas, Kirsch, Wolff, Kitchen, Neil D., Klaas, James P., Klein, Joshua P., Kliot, Michel, Knightly, John J., Knopman, Jared, Ko, Andrew L., Koerner, John D., Kokoszka, Malgosia A., Kolias, Angelos G., Korja, Miikka, Kosztowski, Thomas, Krauss, Joachim K., Krishna, Chandan, Krishna, Vibhor, Krishnaney, Ajit A., Kubben, Pieter L., Kuhn, Jens, Kulkarni, Abhaya V., Kumar, Gomatam R. Vijay, Kuntz, Charles, IV, Kuo, Jeffrey V., Kwan, Kenny, La Marca, Frank, Laack, Nadia N. Issa, Ladha, Alim M., Lafage, Virginie, Lam, Arthur M., Lamki, Tariq, Lang, Frederick F., Lanzino, Giuseppe, Larson, Paul, Lau, Catherine Y., Lau, Darryl, Lavine, Sean D., Lawler, Sean E., Laws, Edward R., Jr., Lawton, Michael T., Laxpati, Nealen G., Lazarus, Joash T., Le, Peter D., Lebed, Brett D., Lee, Cheng-Chia, Lee, Sangmi, Lee, Young M., Lehman, Ronald A., Jr., Lenke, Lawrence G., Leuthardt, Eric C., Levin, Emily Lehmann, Levitt, Michael R., Lewis, Evan M., Li, Dianyou, Liang, Lydia J., Liauw, Jason, Lichtenbaum, Roger, Limbrick, David D., Jr., Lin, Kant Y., Lingsma, Hester F., Linskey, Mark E., Lipsman, Nir, Litvak, Zachary N., Liu, James K., Liu, Kenneth C., Liu, Wei, Lizarraga, Karlo J., Lober, Robert M., Loftus, Christopher M., Lonser, Russell R., Louvi, Angeliki, Lozano, Andres M., Luciano, Mark G., Lukas, Rimas V., Lund, Teija, Ma, Lijun, Ma, Tracy S., Maas, Andrew I.R., Macdonald, R. Loch, Mack, Stephen C., MacLachlan, Lara S., Macyszyn, Luke, Magarik, Jordan A., Maggio, Dominic, Magistretti, Pierre J., Mahaney, Kelly B., Maher, Cormac O., Mahmoodi, Ramin, Mahmoudi, Babak, Malessy, Martijn J.A., Mallucci, Conor, Mangano, Francesco T., Maniker, Allen H., Manley, Geoffrey T., Manolidis, Spiros, Marchac, Daniel, Marchione, Joseph, Marcus, Joshua, Maroon, Joseph C., Martin, Alastair, Martin, Neil A., Mascitelli, Justin R., Mathur, Amit, Maulucci, Christopher M., Mazur, Marcus D., Mazwi, Nicole, McAllister, James P., II, McClain, Craig D., McCutcheon, Ian E., McDougall, Cameron G., McEvoy, Andrew W., McGoldrick, Patricia E., McGovern, Robert A., III, McKhann, Guy M., II, Meaney, David F., Medel, Ricky, Mehta, Minesh P., Melega, William P., Menezes, Arnold H., Mertens, Patrick, Meyer, Fredric B., Meyer, R. Michael, IV, Meyer, Scott A., Meyers, Emma, Meyers, Philip M., Midha, Rajiv, Milano, Jerônimo Buzetti, Miller, Catherine, Miller, Charles A., Miller, Jonathan P., Miller, Neil R., Mirza, Farhan A., Miserocchi, Anna, Misra, Basant K., Missios, Symeon, Miyashiro, Kevin Y., Mizuno, Junichi, Mocco, J., Modic, Michael T., Moeller, Jeremy J., Mokin, Maxim, Monteith, Stephen J., Moon, Karam, Morales-Valero, Saul F., Morcos, Jacques J., Morgan, Michael Kerin, Moses, Ziev B., Moss, S. David, Moussazadeh, Nelson, Muizelaar, J. Paul, Mukherjee, Pratik, Mukundan, Srinivasan, Jr., Mummaneni, Praveen V., Munich, Stephan A., Muraszko, Karin, Murray-Ortiz, Gisela, Mussi, Antônio C.M., Nagel, Sean J., Nagy, Gábor, Najm, Imad M., Nakaji, Peter, Nakajima, Takeshi, Nakashima, Hiroaki, Nater, Anick, Navarro-Ramirez, Rodrigo, Nduom, Edjah K., Nelp, Taylor B., Nerva, John D., Nery, Breno, Newell, David W., Ng, Angela Li Ching, Nicholas, M. Kelly, Niimi, Yasunari, Nimjee, Shahid M., North, Richard B., Nowell, Mark, Nurmikko, Turo J., Nuwer, Marc R., Oakes, W. Jerry, Ochiai, Taku, Ogilvy, Christopher S., Oh, Michael Y., Oh, Nathan, Okonkwo, David O., Okun, Michael S., Oldfield, Edward H., Olivi, Alessandro, O'Neill, Francis, Orgill, Dennis P., Osbun, Joshua W., Özduman, Koray, Pacia, Steven V., Pai, Nikhil S., Pain, Margaret, Palacios, Eva M., Palmer, James N., Pamir, M. Necmettin, Pan, Edward, Panczykowski, David M., Panov, Fedor E., Parajón, Avelino, Paramasivam, Srinivasan, Parent, Andrew D., Park, Michael S., Park, Min S., Park, Paul, Park, T.S., Parsa, Andrew T., Partington, Michael D., Patel, Akash J., Patel, Aman B., Patel, Vimal, Patil, Parag G., Payne, Russell, Penn, Richard Deren, Pennicooke, Brenton H., Perez, Augustus J., Perin, Alessandro, Perlmutter, Joel S., Persing, John A., Petersen, Erika A., Peterson, Eric C., Petraglia, Anthony L., Pham, Martin, Piazza, Matthew A., Piepmeier, Joseph M., Pilcher, Webster H., Pinckard-Dover, Heather N., Pineda, José A., Pinter, Joseph D., Pisapia, Jared M., Pisculli, Mary L., Pittman, Thomas, Pohl, Pedro H.I., Pollack, Ian F., Pollock, Bruce E., Post, Kalmon D., Potter, Wyatt, Potts, Matthew B., Pouratian, Nader, Pradilla, Gustavo, Prager, Briana C., Prestigiacomo, Charles J., Proctor, Mark R., Prolo, Laura M., Prost, Robert W., Puduvalli, Vinay K., Purger, David, Quiñones-Hinojosa, Alfredo, Rahal, Jason Pierce, Ram, Zvi, Ranalli, Nathan J., Rangel-Castilla, Leonardo, Raper, Daniel M.S., Rapoport, Benjamin I., Raskin, Jeffrey S., Raslan, Ahmed M., Rasmussen, Peter, Rasouli, Jonathan, Ravanpay, Ali C., Ravindra, Vijay M., Ray, Wilson Z., Raz, Eytan, Raza, Shaan M., Régis, Jean, Reilly, Peter L., Reith, Florence C.M., Renier, Dominique, Resnick, Daniel K., Reynolds, Renée, Rezai, Ali, Rhines, Laurence D., Rhoton, Albert L., Jr., Ribalta, Teresa, Ricci, Joseph A., Richardson, R. Mark, Riggins, Callen J., Riggins, Gregory J., Riina, Howard A., Rincon-Torroella, Jordina, Ringer, Andrew J., Riva-Cambrin, Jay, Roark, Christopher D., Roberts, David W., Robertson, Claudia S., Robertson, Jon H., Robinson, Shenandoah, Roche, Aidan D., Roche, Pierre-Hugues, Rodríguez-Hernández, Ana, Roguski, Marie, Roland, Jarod L., Rolston, John D., Root, Brandon K., Rosenberg, William S., Rosenow, Joshua M., Rosenthal, Guy, Rosenwasser, Robert H., Rosner, Michael K., Rovner, Eric S., Rucker, Janet C., Russell, Stephen M., Russin, Jonathan J., Rutka, James T., Safain, Mina G., Sagher, Oren, Sahgal, Arjun, Saigal, Rajiv, Saito, Nobuhito, Salminger, Stefan, Samdani, Amer F., Sammartino, Francesco, Sanai, Nader, Sanborn, Matthew R., Sandler, Adam L., Sansur, Charles A., Santarius, Thomas, Santiago, Paul, Santiago-Sim, Teresa, José Santos de Moraes, Osmar, Sarkiss, Christopher A., Sarnat, Harvey B., Sarris, Christina, Sawaya, Raymond, Scheer, Justin K., Scheld, W. Michael, Schiff, Nicholas D., Schlesinger, David J., Schmidt, Meic H., Schmitt, Paul J., Schramm, Johannes, Schwab, Frank J., Sciubba, Daniel M., Scott, R. Michael, Scranton, Robert A., Seifert, Volker, Selden, Nathan R., Sellin, Jonathan N., Selman, Warren R., Serafini, Sandra, Serizawa, Toru, Shaffrey, Christopher I., Sr., Shah, Kushal J., Shah, Lubdha M., Shah, Manish N., Shahlaie, Kiarash, Shapira, Yuval, Shapiro, Maksim, Sharma, Deepak, Sharma, Mayur, Sharma, Mohan Raj, Shaw, Andrew, Sheehan, Jason P., Sheehan, Jonas M., Shiflett, James M., Shilpakar, Sushil Krishna, Shils, Jay L., Shin, Alexander Y., Shin, Samuel S., Siddiqui, Adnan H., Siddiqui, Mustafa S., Silvestri, David M., Sindou, Marc, Singer, Robert J., Singh, Jeffrey M., Singh, Manish K., Sivakumar, Walavan, Slavin, Justin, Smith, Edward R., Smith, Justin S., Smith, Timothy R., Smith, Yoland, Solomon, Robert A., Sonabend, Adam M., Sonntag, Volker K.H., Sorenson, Jeffrey M., Soriano, Sulpicio G., Soriano-Baron, Hector, Souweidane, Mark M., Sowa, Gwendolyn A., Spatola, Giorgio, Spears, Julian, Spencer, Dennis D., Spetzler, Robert F., Spinner, Robert J., St. Clair, Eric G., Starke, Robert M., Starr, Philip, Stefko, S. Tonya, Stein, Sherman C., Steinberg, Gary K., Stephens, Bradley H., Stephens, Frederick L., Stern, Matthew A., Steyerberg, Ewout W., Stieg, Philip E., Stone, Scellig S.D., Strom, Russell G., Strowd, Roy E., III, Sughrue, Michael E., Suh, John H., Suki, Dima, Sulaiman, Wale A.R., Sun, Bomin, Tagliati, Michele, Taira, Takaomi, Takagi, Yasushi, Tamargo, Rafael J., Tanaka, Shota, Tandon, Nitin, Tanweer, Omar, Tate, Jessica A., Tate, Matthew C., Tatsui, Claudio E., Taylor, Blake E.S., Taylor, Michael D., Telian, Steven A., Tempel, Zachary J., Teo, Charles, Tessier, Jeffrey M., Than, Khoi D., Theadom, Alice, Theodore, Nicholas, Thompson, B. Gregory, Jr., Tilton, Ann H., Timmons, Shelly D., Tomycz, Nestor D., Torres-Reveron, Juan, Toth, Gabor, Toussaint, Charles P., Tran, Duc A., Trapp, Bruce D., Tubbs, R. Shane, Tunkel, Allan R., Türe, Ugur, Hassoun Turkmani, Ali, Uribe, Juan S., Ushe, Mwiza, Vaccaro, Alexander R., van den Bent, Martin J., Van Gompel, Jamie J., van Overbeeke, J.J., van Santbrink, Henk, Vasquez, Ciro, Vasudeva, Viren S., Vellimana, Ananth K., Verlicchi, Angela, Vialle, Emiliano, Viapiano, Mariano S., Vira, Shaleen, Virk, Michael S., Visser-Vandewalle, Veerle, Vitek, Jerrold L., Vo, Nam, Vogelbaum, Michael A., Volpini, Matthew, Wackym, P. Ashley, Wadhwa, Rishi, Wainwright, Mark S., Waldau, Ben, Walker, Marion L., Wallace, M. Christopher, Wallace, Scott A., Walsh, Kyle M., Wang, Huan, Wang, Michael Y., Wang, Shelly, Wang, Tony R., Wang, Vincent Y., Wang, Xin, Warnick, Ronald E., Weil, Robert J., Weiner, Howard L., Weingart, Jon D., Weiss, Martin H., Weiss, Nirit, Weller, Michael, Wellons, John C., III, Wen, Hung Tzu, Wen, Patrick Y., West, G. Alexander, White, Jonathan, Whiting, Alexander C., Whiting, Donald M., Wichmann, Thomas, Wildrick, David M., Wilkinson, D. Andrew, Winer, Jesse L., Winfree, Christopher J., Winkler, Ethan A., Winn, H. Richard, Wisoff, Jeffrey H., Witsch, Jens, Wolf, Steven M., Wolfla, Christopher E., Wolinsky, Jean-Paul, Wong, Cyrus C., Wong, Eric T., Wrensch, Margaret R., Wu, Jau-Ching, Xu, Linda Wei, Xu, Zhiyuan, Yan, Carol H., Yap, Edward, Yarbrough, Chester K., Yasuno, Katsuhito, Yavin, Daniel, Yener, Ulaş, Yonekawa, Yasuhiro, Young, Timothy P., Youngblood, Mark W., Youngerman, Brett E., Yu, Jennifer S., Yue, John K., Yuh, Esther L., Zabramski, Joseph M., Zacest, Andrew C., Zacko, J. Christopher, Zada, Gabriel, Zadicario, Eyal, Zadnik, Patricia Leigh, Zafonte, Ross D., Zager, Eric L., Zanotti, Bruno, Zellner, Elizabeth G., Zhan, Shikun, Zhang, Chencheng, Zhang, Xiaoxiao, Zhang, Y. Jonathan, Zisakis, Athanasios K., Zuckerman, Scott L., Zumofen, Daniel W., and Zwienenberg-Lee, Marike
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- 2017
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16. Effect of different home-cooking methods on the bioaccessibility of zinc and iron in conventionally bred cowpea (Vigna unguiculata L. Walp) consumed in Brazil.
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Pereira, Elenilda J., Carvalho, Lucia M. J., Dellamora-Ortiz, Gisela M., Cardoso, Flávio S. N., and Carvalho, José L. V.
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ANALYSIS of variance ,BIOAVAILABILITY ,COOKING ,IRON ,LEGUMES ,PROBABILITY theory ,RESEARCH funding ,ZINC ,DATA analysis software - Abstract
Background: The cowpea (Vigna unguiculata L. Wap.) is an excellent source of iron and zinc. However, iron from plant sources is poorly absorbed compared with iron from animal sources. Objectives: The objective of this study was to evaluate iron and zinc bioaccessibility in cowpea cultivars after processing. Methods: Zinc and iron bioaccessibilities in cowpea samples were determined based on an in vitro method involving simulated gastrointestinal digestion with suitable modifications. Results: When water-soaked beans were cooked in a regular pan, the highest percentage of bioaccessible iron obtained was 8.92%, whereas when they were cooked in a pressure cooker without previous soaking, the highest percentage was 44.33%. Also, the percentage of bioaccessible zinc was 52.78% when they were cooked in a regular pan without prior soaking. Higher percentages of bioaccessible iron were found when cooking was done in a pressure cooker compared with regular pan cooking. In all cultivars, cooking of cowpea beans in both pressure cooker and in a regular pan yielded higher percentages of bioaccessible zinc compared with availability of bioaccessible iron. Conclusions: Iron bioaccessibility values suggest that cooking in a regular pan did not have a good effect on iron availability, since the percentage of bioaccessible iron was lower than that of zinc. The determination of iron and zinc bioaccessibility makes it possible to find out the actual percentage of absorption of such minerals and allows the development of efficient strategies for low-income groups to access foods with high levels of these micronutrients. [ABSTRACT FROM AUTHOR]
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- 2016
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17. Preparation of a very stable immobilized biocatalyst of glucose oxidase from Aspergillus niger
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Betancor, Lorena, López-Gallego, Fernando, Hidalgo, Aurelio, Alonso-Morales, Noelia, Dellamora-Ortiz, Gisela, Guisán, Jose M., and Fernández-Lafuente, Roberto
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- 2006
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18. Front Cover Image, Volume 42, Issue 6.
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Fé, Luana Xavier Soares Gomes Moura, Cipolatti, Eliane Pereira, Pinto, Martina Costa Cerqueira, Branco, Suema, Nogueira, Fábio César Sousa, Ortiz, Gisela Maria Dellamora, Pinheiro, Anderson de Sá, and Manoel, Evelin Andrade
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HUMAN body - Published
- 2022
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19. Increasing the binding strength of proteins to PEI coated supports by immobilizing at high ionic strength
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Pessela, Benevides C.C., Betancor, Lorena, Lopez-Gallego, Fernando, Torres, Rodrigo, Dellamora-Ortiz, Gisela M., Alonso-Morales, Noelia, Fuentes, Manuel, Fernández-Lafuente, Roberto, Guisán, José M., and Mateo, Cesar
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- 2005
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20. Effects of cooking methods on the iron and zinc contents in cowpea (Vigna unguiculata) to combat nutritional deficiencies in Brazil.
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Pereira, Elenilda J., Carvalho, Lucia M. J., Dellamora-Ortiz, Gisela M., Cardoso, Flávio S. N., Carvalho, José L. V., Viana, Daniela S., Freitas, Sidinea C., and Rocha, Maurisrael M.
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PREVENTION of malnutrition ,IRON deficiency anemia prevention ,COOKING equipment ,ANALYSIS of variance ,COMPARATIVE studies ,COOKING ,IRON ,LEGUMES ,NUTRITIONAL requirements ,ZINC ,NUTRITIONAL value - Abstract
Background: Because iron deficiency anemia is prevalent in developing countries, determining the levels of iron and zinc in beans, the second most consumed staple food in Brazil, is essential, especially for the low-income people who experience a deficiency of these minerals in their diet. Objectives: This study aimed to evaluate the effect of cooking methods by measuring the iron and zinc contents in cowpea cultivars before and after soaking to determine the retention of these minerals. Methods: The samples were cooked in both regular pans and pressure cookers with and without previous soaking. Mineral analyses were carried out by Spectrometry of Inductively Coupled Plasma (ICP). Results: The results showed high contents of iron and zinc in raw samples as well as in cooked ones, with the use of regular pan resulting in greater percentage of iron retention and the use of pressure cooker ensuring higher retention of zinc. Conclusions: The best retention of iron was found in the BRS Aracê cultivar prepared in a regular pan with previous soaking. This cultivar may be indicated for cultivation and human consumption. The best retention of zinc was found for the BRS Tumucumaque cultivar prepared in a pressure cooker without previous soaking. [ABSTRACT FROM AUTHOR]
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- 2014
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21. In vivo and in vitro evaluation of octyl methoxycinnamate liposomes.
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Varjão Mota, Aline de Carvalho, de Freitas, Zaida Maria Faria, Ricci Júnior, Eduardo, Dellamora-Ortiz, Gisela Maria, Santos-Oliveira, Ralph, Ozzetti, Rafael Antonio, Vergnanini, André Luiz, Ribeiro, Vanessa Lira, Silva, Ronald Santos, and dos Santos, Elisabete Pereira
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- 2013
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22. ChemInform Abstract: Rapid and Efficient Synthesis of Five- to Eight-Membered Cyclic Aminals under Ultrasound Irradiation.
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Ramirez, Maria A., Ortiz, Gisela, Levin, Gustavo, McCormack, Walter, Blanco, Maria M., Perillo, Isabel A., and Salerno, Alejandra
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- *
CYCLIC compounds synthesis , *PYRIMIDINE derivatives , *SONOCHEMISTRY , *MICROWAVE chemistry , *ANNULATION , *MECHANICAL chemistry , *DIAZEPINES , *FORMALDEHYDE - Abstract
The simple procedure using high intensity ultrasound allows the synthesis of cyclic aminals from diamines (I) with aqueous formaldehyde in excellent yields and very short reaction times. [ABSTRACT FROM AUTHOR]
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- 2015
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23. ChemInform Abstract: A Novel Alkylation Procedure Using MW Irradiation for the Synthesis of 1,2,3-Trisubstituted 1,4,5,6,7,8-Hexahydro-1,3-diazocinium Salts from Their Corresponding 1,2-Diaryldiazocines.
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Ramirez, Maria A., Ortiz, Gisela M., Salerno, Alejandra, Perillo, Isabel A., and Blanco, Maria M.
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- 2012
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24. ChemInform Abstract: New Synthetic Routes for N-Substituted 1,n-Diamines. Part 2. Synthesis of Selectively N-Substituted Tetra- and Pentamethylenediamines from ω-Alkanoic Acid Derivatives.
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Ramirez, Maria A., Corona, Maria V., Ortiz, Gisela, Salerno, Alejandra, Perillo, Isabel A., and Blanco, Maria M.
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- 2011
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25. Partial purification and characterization of the interconvertible forms of trehalase from Saccharomyces cerevisiae
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Dellamora-Ortiz, Gisela M., Ortiz, Claudio H.D., Maia, JoséCarlos C., and Panek, Anita D.
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- 1986
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26. Kinetic resolution of amine-alcohols and esters by insolubilized microbial lipases
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López, Claudia Ortiz, Barbosa, Oveimar, Escorcia, Andrés, Dellamora-Ortiz, Gisela, and Torres, Rodrigo
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- 2008
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27. In vivo and in vitro evaluation of octyl methoxycinnamate liposomes.
- Author
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Mota Ade C, de Freitas ZM, Ricci Júnior E, Dellamora-Ortiz GM, Santos-Oliveira R, Ozzetti RA, Vergnanini AL, Ribeiro VL, Silva RS, and dos Santos EP
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- Adult, Animals, Cinnamates chemistry, Female, Humans, Hydrolysis, Liposomes chemistry, Middle Aged, Organotechnetium Compounds chemistry, Rats, Rats, Wistar, Skin chemistry, Sunscreening Agents chemistry, Surgical Tape, Tissue Distribution, Young Adult, Cinnamates pharmacokinetics, Liposomes pharmacokinetics, Organotechnetium Compounds pharmacokinetics, Sunscreening Agents pharmacokinetics
- Abstract
Unlabelled: Solar radiation causes damage to human skin, and photoprotection is the main way to prevent these harmful effects. The development of sunscreen formulations containing nanosystems is of great interest in the pharmaceutical and cosmetic industries because of the many potential benefits. This study aimed to develop and evaluate an octyl methoxycinnamate (OMC) liposomal nanosystem (liposome/OMC) to obtain a sunscreen formulation with improved safety and efficacy by retaining OMC for longer on the stratum corneum., Methods: The liposome/OMC nanostructure obtained was tested for enzymatic hydrolysis with lipase from Rhizomucor miehei and biodistribution with liposomes labeled with technetium-99m. The liposome/OMC formulation was then incorporated in a gel formulation and tested for ocular irritation using the hen's egg test-chorio-allantoic membrane (HET-CAM) assay, in vitro and in vivo sun protection factor, in vitro release profile, skin biometrics, and in vivo tape stripping., Results: The liposome/OMC nanosystem was not hydrolyzed from R. miehei by lipase. In the biodistribution assay, the liposome/OMC formulation labeled with technetium-99m had mainly deposited in the skin, while for OMC the main organ was the liver, showing that the liposome had higher affinity for the skin than OMC. The liposome/OMC formulation was classified as nonirritating in the HET-CAM test, indicating good histocompatibility. The formulation containing liposome/OMC had a higher in vivo solar photoprotection factor, but did not show increased water resistance. Inclusion in liposomes was able to slow down the release of OMC from the formulation, with a lower steady-state flux (3.9 ± 0.33 μg/cm(2)/hour) compared with the conventional formulation (6.3 ± 1.21 μg/cm(2)/hour). The stripping method showed increased uptake of OMC in the stratum corneum, giving an amount of 22.64 ± 7.55 μg/cm(2) of OMC, which was higher than the amount found for the conventional formulation (14.57 ± 2.30 μg/cm(2))., Conclusion: These results indicate that liposomes are superior carriers for OMC, and confer greater safety and efficacy to sunscreen formulations.
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- 2013
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28. DNA methylation: a promising target for the twenty-first century.
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Abreu PA, Dellamora-Ortiz G, Leão-Ferreira LR, Gouveia M, Braggio E, Zalcberg I, Santos DO, Bourguinhon S, Cabral LM, Rodrigues CR, and Castro HC
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- DNA genetics, DNA Modification Methylases chemistry, DNA Modification Methylases genetics, DNA Modification Methylases metabolism, Humans, Antineoplastic Agents pharmacology, DNA metabolism, DNA Methylation drug effects, Neoplasms drug therapy
- Abstract
Background: Over the last few years DNA methylation and its involvement in diseases such as cancer has become of great interest for applied research. Since reversal of aberrant DNA methylation may influence the behavior of tumors, the methylation of DNA CpG sites is a potential target for the development of inhibitors for use in cancer treatment., Objective/methods: We briefly review the structural and mechanistic features of DNA methylation, including a structural analysis of the three main human DNA methyltransferases and some (pre)clinical results., Results/conclusion: Despite side effects, data obtained to date still support the vision that DNA-methylation, possibly associated with the use of histone deacetylases (HDACs) and/or artificial transcription factors (ATFs), is a promising target for improving anticancer therapy in the 21st century.
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- 2008
- Full Text
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