16 results on '"O.V. Klimenko"'
Search Results
2. CLINICAL CASE OF COVID-ASSOCIATED GUILLAIN-BARRE SYNDROME
- Author
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U.M. Petrova, Yu.Yu. Garmash, O.V. Klimenko, V.V. Bedny, O.G. Mylnikova, and V.M. Eagle
- Subjects
guillain-barre syndrome ,covid-19 ,electroneuromyography ,Medicine - Abstract
The aim of our article is to shed light on the problem of the development of Guillain-Barre syndrome after COVID-19 infection Materials and methods The main research methods we used were scientific research and the actual description of our own clinical case. Laboratory research methods, magnetic resonance imaging, and electromyography were used to confirm the diagnosis and perform differential diagnostics. Results. In 2021, the Center for Acute Neurology and Pain Treatment treated 12 patients with Guillain-Barre syndrome. Guillain-Barre syndrome (GBS) is an acute autoimmune inflammatory polyradiculoneuropathy. The clinical picture of GBS includes progressive motor and sensory disorders in the extremities and pain. We bring to your attention a clinical case of GBS in patient B., who was treated at the clinical hospital "Feofania". Patient B., 32 years old, was hospitalized in the Feofania Clinical Hospital with complaints of weakness in her arms and legs, inability to walk, foreign body sensation in the throat, difficulty swallowing, chest discomfort, and difficulty breathing. A few weeks before the disease, the patient was treated for a mild SARS-CoV-2 infection. The patient's condition gradually deteriorated by day 25 of the disease, despite plasmapheresis, intravenous immunoglobulin and glucocorticoid therapy. However, from day 29, the condition gradually improved and on re-examination after 2 months, the patient remained mild distal paresis of the leg muscles (up to 4 points), decreased tendon reflexes from the lower extremities. Disorders of sensitivity and function of the pelvic organs were not observed. Conclusion. In our article, we present a case of COVID-19-associated GBS with a classic clinical picture, increased peripheral paresis, stabilization, and gradual recovery of all functions (respiration, pelvic function, motor, sensory, and reflex) through pathogenetic treatment and follow-up rehabilitation measures.
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- 2022
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3. Spectral Estimation of Chlorophyll for Non-Invasive Assessment in Apple Orchards.
- Author
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Szabó, Andrea, Tamás, János, and Nagy, Attila
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STANDARD deviations ,APPLE orchards ,PRINCIPAL components analysis ,CHLOROPHYLL ,REGRESSION analysis - Abstract
The main aim of our research was to develop a methodology of chlorophyll content in the leaves of apple trees non-invasive assessment in apple orchards and its adaptation to Early Gold and Golden Reinders based on spectral characteristics of chlorophyll content in the canopy. In each measurement period, 30 samples were collected from each of the two apple cultivars studied. For spectral data collection of leaf samples, an AvaSpec 2048 spectrometer was used in the wavelength range 400–1000 nm in three replicates. Principal component analysis (PCA) with varimax rotation was used to identify the wavelength with the highest factor weight to identify the chlorophyll-sensitive wavelength. The models were calibrated with 2/3 of the values in the database and validated with the remaining 1/3. The simple linear regression method generated the model for estimating chlorophyll. The coefficient of determination (R
2 ) was used to compare the strength of the regression models, and the Root Mean Square Error (RMSE), Normalized Root Mean Square Error (NRMSE), Nash–Sutcliffe efficiency (NSE), Mean Absolute Error (MAE) and Mean Bias Error (MBE) functions were used to measure the accuracy of the estimator models. These metrics help to quickly assess how reliable and accurate a model's predictions are. Nine indices were obtained based on the precision values, and CHLapple1 performed best (R2 = 0.633, RMSE = 298.28 µg/g, NRMSE = 9.61%, NSE = 0.60, MBE = 84.59, and MAE = 243.39). [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
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4. A review on common root rot of wheat and barley in Australia.
- Author
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Xiong, Yiyi, McCarthy, Cheryl, Humpal, Jacob, and Percy, Cassandra
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BARLEY ,WHEAT ,COST control ,ROOT rots ,PLANT diseases ,BIPOLARIS - Abstract
Common root rot (CRR) caused by the soilborne pathogen Bipolaris sorokiniana (teleomorph Cochliobolus sativus) is becoming increasingly prevalent worldwide. Identification of CRR is difficult and time‐consuming for human assessors due to the non‐distinctive above‐ground symptoms, with browning of subcrown internodes and roots the most distinguishing symptom of infection. CRR disease has been recognized as a significant disease for cereal crops in many countries. In 2009, CRR in Australia was estimated to cause $30 million average annual yield loss for wheat and $13 million for barley. Recent evidence indicates CRR may be more prevalent than expected in Australian wheat cropping areas due to lack of research on this disease. Low levels of B. sorokiniana survive in the soil for up to 10 years and attack plants at early stages of growth. Therefore, mitigating CRR in wheat and barley may not be practical at the late stages of infection due to lack of effective methods; however, early detection might be viable to alleviate the impact of this disease. A comprehensive overview of CRR caused by B. sorokiniana, including disease background, worldwide economic losses, management methods, potential CRR detection using multispectral and hyperspectral sensors and the research focus over the past 50 years is provided in this article. This review paper is expected to provide thorough supplemental information for current studies about CRR and proposes recommendations for whole‐of‐field disease scouting methods to farmers, enabling reduced time and cost for CRR management and increasing wheat and barley production worldwide. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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5. Genotype-Specific Features of Cold-Induced Sweetening Process Regulation in Potato Varieties Nikulinsky, Symfonia, and Nevsky.
- Author
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Egorova, A. A., Saboiev, I. A., Kostina, N. E., Kuvaeva, D. D., Shcherban, A. B., Ibragimova, S. M., Salina, E. A., and Kochetov, A. V.
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POTATOES ,INVERTASE ,SUCROSE ,TUBERS ,LOW temperatures - Abstract
Abstract—In this study, we performed expression analysis of genes associated with cold-induced sweetening in potato tubers: vacuolar invertase (Pain-1), sucrose synthase (SUS4), and invertase inhibitor (InvInh2). Potato varieties Nikulinsky, Symfonia, and Nevsky were used. All three varieties were found to accumulate sugars at low temperatures; the maximum accumulation of reducing sugars was observed at 4°C. It was found that the expression pattern of genes associated with cold-induced sweetening differs depending on the variety and storage duration. The increased expression of vacuolar invertase and its inhibitor is more pronounced at the beginning of storage period, whereas the increased expression of sucrose synthase is more pronounced after 3 months of storage. At early storage periods, high expression of invertase and low expression of inhibitor is observed in the Dutch variety Symfonia, and vice versa in the Russian varieties Nikulinsky and Nevsky. The involvement of the studied genes in the process of cold-induced sweetening is discussed. [ABSTRACT FROM AUTHOR]
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- 2023
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6. Vacuum Carbon Reducing Iron Oxide Scale to Prepare Porous 316 Stainless Steel.
- Author
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Zhang, Fang, Peng, Jun, Chang, Hongtao, and Wang, Yongbin
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FERRIC oxide ,STAINLESS steel ,IRON oxides ,ROLLING (Metalwork) ,CHROMIUM ,MAGNETIC separation ,METAL powders ,IRON oxide nanoparticles - Abstract
In order to improve the added value of iron oxide scale and reduce the manufacturing cost of porous stainless steel, steel rolling iron oxide scale as an iron-containing raw material was used to prepare porous 316 stainless steel by high-temperature sintering under vacuum conditions, while carbon was used as a reducing agent and pore-forming agent, and the necessary metal powders were added. In our work, the specific reduction system was confirmed, including the sintering temperature, sintering time, vacuum degree and carbon amount, through thermodynamic calculation combined with experiments. Thermodynamic analysis results showed that the transformation process of the chromium element in the raw materials at 10
−4 atm and 300~1600 °C was FeCr2 O4 + Cr3 O4 →Cr2 O3 + Cr3 O4 + Cr23 C6 →Cr23 C6 + Cr7 C3 + FCC→FCC + Cr23 C6 →FCC→FCC + BCC→Cr(liq). The FCC phase with qualified carbon content could be obtained at 10−4 atm and 1200 °C, while 90.88 g iron oxide scale, 17.17 g carbon, 17.00 g metal chromium, 12.00 g metal nickel and 2.5 g metal molybdenum were necessary to produce 100 g porous 316 stainless steel. The porous 316 stainless steel with a carbon content of 0.025% could be obtained at 10−4 atm and 1200 °C for 180 min, while the chromium element underwent the transformation of metal, Cr→FeCr2 O4 →Cr23 C6 →Austenite. The porosity of the porous 316 stainless steel was 42.07%. The maximum size of impurity particles was 5 μm when the holding time reached 180 min. Magnetic separation was an effective method to reduce impurities in the porous stainless steel. [ABSTRACT FROM AUTHOR]- Published
- 2022
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7. Assessment of Ultraviolet Impact on Main Pigment Content in Purple Basil (Ocimum basilicum L.) by the Spectrometric Method and Hyperspectral Images Analysis.
- Author
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Proshkin, Yuri A., Smirnov, Alexandr A., Semenova, Natalya A., Dorokhov, Alexey S., Burynin, Dmitry A., Ivanitskikh, Alina S., and Panchenko, Vladimir A.
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BASIL ,IMAGE analysis ,ULTRAVIOLET radiation ,PIGMENTS ,CULTIVARS ,CAROTENOIDS - Abstract
This research is aimed at the assessing the impact of the ultraviolet radiation in the A, B, and C ranges (as additives to the main light) on general plan condition, the stress experienced by them, the pigment concentration in the leaves and leaf reflective characteristics. Under studying, there were the photo-protective reactions of the purple variety basil plants. The plants were grown in plastic pots in a phyto-chamber equipped with an automatic microclimate system. The phyto-chamber was divided into four compartments where, in addition to the main lighting, there were installed the additional LEDs emitting their radiation in the ranges UV-A, UV-B, and UV-C. Plant reactions were evaluated by the contents of the main pigments as detected by the spectrometric method. Then correlations were revealed between those values and the vegetative indices obtained based on the hyperspectral images. A strong correlation (R
2 ˃ 0.83) was observed between the values of the vegetative indices ARI and mARI and the anthocyanins concentration in basil leaves. A weak correlation (R2 = 0.0479) was found between the ARI and mARI values and the carotenoids index CRI700, which is attributed to the shielding effect of the anthocyanins. Deviations in the results are influenced by leaf surface unevenness, its thickness and density. Additional research is needed including developing reflection indices taking into account the shielding effect of the purple pigments. [ABSTRACT FROM AUTHOR]- Published
- 2021
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8. Early Identification of Root Rot Disease by Using Hyperspectral Reflectance: The Case of Pathosystem Grapevine/ Armillaria.
- Author
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Calamita, Federico, Imran, Hafiz Ali, Vescovo, Loris, Mekhalfi, Mohamed Lamine, and La Porta, Nicola
- Subjects
ROOT rots ,REFLECTANCE ,PLANT diseases ,SPECTRAL reflectance ,WOODY plants ,VITIS vinifera - Abstract
Armillaria genus represents one of the most common causes of chronic root rot disease in woody plants. Prompt recognition of diseased plants is crucial to control the pathogen. However, the current disease detection methods are limited at a field scale. Therefore, an alternative approach is needed. In this study, we investigated the potential of hyperspectral techniques to identify fungi-infected vs. healthy plants of Vitis vinifera. We used the hyperspectral imaging sensor Specim-IQ to acquire leaves' reflectance data of the Teroldego Rotaliano grapevine cultivar. We analyzed three different groups of plants: healthy, asymptomatic, and diseased. Highly significant differences were found in the near-infrared (NIR) spectral region with a decreasing pattern from healthy to diseased plants attributable to the leaf mesophyll changes. Asymptomatic plants emerged from the other groups due to a lower reflectance in the red edge spectrum (around 705 nm), ascribable to an accumulation of secondary metabolites involved in plant defense strategies. Further significant differences were observed in the wavelengths close to 550 nm in diseased vs. asymptomatic plants. We evaluated several machine learning paradigms to differentiate the plant groups. The Naïve Bayes (NB) algorithm, combined with the most discriminant variables among vegetation indices and spectral narrow bands, provided the best results with an overall accuracy of 90% and 75% in healthy vs. diseased and healthy vs. asymptomatic plants, respectively. To our knowledge, this study represents the first report on the possibility of using hyperspectral data for root rot disease diagnosis in woody plants. Although further validation studies are required, it appears that the spectral reflectance technique, possibly implemented on unmanned aerial vehicles (UAVs), could be a promising tool for a cost-effective, non-invasive method of Armillaria disease diagnosis and mapping in-field, contributing to a significant step forward in precision viticulture. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
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9. Conflict in Ukraine: A Review Essay.
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Pennell, John A.
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NONFICTION - Published
- 2019
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10. From cooperation to confrontation: US-Russia relations since 9/11
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German, Tracey
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- 2024
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11. Computational Methods in Drug Discovery and Repurposing for Cancer Therapy
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Ganji Purnachandra Nagaraju, Venkatesan Amouda, Ampasala Dinakara Rao, Ganji Purnachandra Nagaraju, Venkatesan Amouda, and Ampasala Dinakara Rao
- Abstract
Computational Methods in Drug Discovery and Repurposing for Cancer Therapy provides knowledge about ongoing research as well as computational approaches for drug discovery and repurposing for cancer therapy. The book also provides detailed descriptions about target molecules, pathways, and their inhibitors for easy understanding and applicability. The book discusses tools and techniques such as integrated bioinformatics approaches, systems biology tools, molecular docking, computational chemistry, artificial intelligence, machine learning, structure-based virtual screening, biomarkers, and transcriptome; those are discussed in the context of different cancer types, such as colon, pancreatic, glioblastoma, endometrial, and retinoblastoma, among others. This book is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about the use of computational modeling to better tailor the treatment for cancer patients. - Discusses in silico remodeling of effective phytochemical compounds for discovering improved anticancer agents for substantial/significant cancer therapy - Covers potential tools of bioinformatics that are applied toward discovering new targets by drug repurposing and strategies to cure different types of cancers - Demonstrates the significance of computational and artificial intelligence approaches in anticancer drug discovery - Explores how these various advances can be integrated into a precision and personalized medicine approach that can eventually enhance patient care
- Published
- 2023
12. The 2nd International Conference Material Engineering and Application
- Author
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Mosbeh Kaloop and Mosbeh Kaloop
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- Materials science--Congresses, Materials--Congresses
- Abstract
Selected, peer reviewed papers from the 2nd International Conference on Material Engineering and Application (2nd ICMEA 2017), August 18-20, 2017, Shanghai, China
- Published
- 2018
13. Scientists at Charles University Discuss Research in Apoptosis
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Research ,Apoptosis -- Research ,Universities and colleges -- Czech Republic ,Health ,Scientists - Abstract
A report, 'Regulation of immune responses, apoptosis, and tumorigenesis by separate FOXP-3-dependent genes: connection with clinical manifestations,' is newly published data in Journal of Microbiology, Immunology, and Infection. According to [...]
- Published
- 2012
14. Data on Cancer Gene Therapy Detailed by Researchers at Cancer Center
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Genetic aspects ,Health aspects ,Cancer treatment -- Health aspects ,Genetic research -- Health aspects ,Cancer genetics -- Genetic aspects -- Health aspects ,Gene therapy -- Health aspects ,Cancer -- Genetic aspects -- Health aspects ,Cancer research -- Health aspects ,Oncology, Experimental -- Health aspects ,Cancer -- Care and treatment -- Genetic aspects -- Health aspects -- Research - Abstract
By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- Investigators discuss new findings in Cancer Gene Therapy. According to news reporting from Moscow, Russia, by NewsRx journalists, [...]
- Published
- 2013
15. Researchers from Cancer Center Discuss Findings in Cancer Gene Therapy
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Genetic aspects ,Research ,Health aspects ,Cancer treatment -- Health aspects ,Genetic research -- Health aspects ,Cancer genetics -- Genetic aspects -- Research -- Health aspects ,Gene therapy -- Health aspects ,Cancer -- Genetic aspects -- Health aspects ,Cancer research -- Health aspects ,Oncology, Experimental -- Health aspects ,Cancer -- Care and treatment -- Genetic aspects -- Health aspects -- Research - Abstract
By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- Researchers detail new data in Cancer Gene Therapy. According to news originating from Moscow, Russia, by NewsRx correspondents, [...]
- Published
- 2013
16. Research from Charles University has provided new data on life science
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Charles University ,Research ,Universities and colleges -- Research - Abstract
Data detailed in 'Influence of the lung mechanical ventilation with injurious parameters on 7-ketocholesterol synthesis in Sus Scrofa' have been presented. According to recent research from Prague, Czech Republic, 'The [...]
- Published
- 2010
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