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1. Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study

Author

Levin, Michael, Coin, Lachlan, Gormley, Stuart, Hamilton, Shea, Hoggart, Clive, Kaforou, Myrsini, Sancho-Shimizu, Vanessa, Wright, Victoria, Abdulla, Amina, Agapow, Paul, Bartlett, Maeve, Eleftherohorinou, Hariklia, Galassini, Rachel, Inwald, David, Mashbat, Meg, Menikou, Stephanie, Mustafa, Sobia, Nadel, Simon, Rahman, Rahmeen, Shailes, Hannah, Thakker, Clare, Bokhandi, S., Power, Sue, Barham, Heather, Pathan, N., Ridout, Jenna, White, Deborah, Thurston, Sarah, Faust, S., Patel, S., McCorkell, Jenni, Davies, P., Crate, Lindsey, Navarra, Helen, Carter, Stephanie, Ramaiah, R., Patel, Rekha, Tuffrey, Catherine, Gribbin, Andrew, McCready, Sharon, Peters, Mark, Hardy, Katie, Standing, Fran, O'Neill, Lauren, Abelake, Eugenia, Deep, Akash, Nsirim, Eniola, Pollard, Andrew, Willis, Louise, Young, Zoe, Royad, C., White, Sonia, Fortune, Peter-Marc, Hudnott, Phil, Martinón-Torres, Federico, Salas, Antonio, Álvez González, Fernando, Barral-Arca, Ruth, Cebey-López, Miriam, Curras-Tuala, María José, García, Natalia, García Vicente, Luisa, Gómez-Carballa, Alberto, Gómez Rial, Jose, Grela Beiroa, Andrea, Justicia Grande, Antonio, Leboráns Iglesias, Pilar, Martínez Santos, Alba Elena, Martinón-Torres, Nazareth, Martinón Sánchez, José María, Morillo Gutiérrez, Beatriz, Mosquera Pérez, Belén, Obando Pacheco, Pablo, Pardo-Seco, Jacobo, Pischedda, Sara, Rivero-Calle, Irene, Rodríguez-Tenreiro, Carmen, Redondo-Collazo, Lorenzo, Salas Ellacuriaga, Antonio, Fernández, Sonia Serén, del Sol Porto Silva, María, Vega, Ana, Vilanova Trillo, Lucía, Reyes, Susana Beatriz, Cruz León León, María, Navarro Mingorance, Álvaro, Gabaldó Barrio, Xavier, Oñate Vergara, Eider, Concha Torre, Andrés, Vivanco, Ana, Fernández, Reyes, Giménez Sánchez, Francisco, Sánchez Forte, Miguel, Rojo, Pablo, Contreras, J. Ruiz, Palacios, Alba, Epalza Ibarrondo, Cristina, Fernández Cooke, Elizabeth, Navarro, Marisa, Álvarez Álvarez, Cristina, José Lozano, María, Carreras, Eduardo, Brió Sanagustín, Sonia, Neth, Olaf, Martínez Padilla, Mª del Carmen, Prieto Tato, Luis Manuel, Guillén, Sara, Fernández Silveira, Laura, Moreno, David, de Groot, R., Tutu van Furth, A.M., van der Flier, M., Boeddha, N.P., Driessen, G.J.A., Emonts, M., Hazelzet, J.A., Kuijpers, T.W., Pajkrt, D., Sanders, E.A.M., van de Beek, D., van der Ende, A., Philipsen, H.L.A., Adeel, A.O.A., Breukels, M.A., Brinkman, D.M.C., de Korte, C.C.M.M., de Vries, E., de Waal, W.J., Dekkers, R., Dings-Lammertink, A., Doedens, R.A., Donker, A.E., Dousma, M., Faber, T.E., Gerrits, G.P.J.M., Gerver, J.A.M., Heidema, J., Homan-van der Veen, J., Jacobs, M.A.M., Jansen, N.J.G., Kawczynski, P., Klucovska, K., Kneyber, M.C.J., Koopman-Keemink, Y., Langenhorst, V.J., Leusink, J., Loza, B.F., Merth, I.T., Miedema, C.J., Neeleman, C., Noordzij, J.G., Obihara, C.C., van Overbeek- van Gils, A.L.T., Poortman, G.H., Potgieter, S.T., Potjewijd, J., Rosias, P.P.R., Sprong, T., ten Tussher, G.W., Thio, B.J., Tramper-Stranders, G.A., van Deuren, M., van der Meer, H., van Kuppevelt, A.J.M., van Wermeskerken, A.M., Verwijs, W.A., Wolfs, T.F.W., Schlapbach, Luregn J., Agyeman, Philipp, Aebi, Christoph, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M., Heininger, Ulrich, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian, Hasters, Paul, Relly, Christa, Baer, Walter, Berger, Christoph, Carrol, Enitan D., Paulus, Stéphane, Frederick, Hannah, Jennings, Rebecca, Johnston, Joanne, Kenwright, Rhian, Fink, Colin G, Pinnock, Elli, Emonts, Marieke, Agbeko, Rachel, Anderson, Suzanne, Secka, Fatou, Bojang, Kalifa, Sarr, Isatou, Kebbeh, Ngange, Sey, Gibbi, Saidykhan, Momodou, Cole, Fatoumata, Thomas, Gilleh, Antonio, Martin, Zenz, Werner, Kohlfürst, Daniela S., Binder, Alexander, Schweintzger, Nina A., Sagmeister, Manfred, Baumgart, Hinrich, Baumgartner, Markus, Behrends, Uta, Biebl, Ariane, Birnbacher, Robert, Blanke, Jan-Gerd, Boelke, Carsten, Breuling, Kai, Brunner, Jürgen, Buller, Maria, Dahlem, Peter, Dietrich, Beate, Eber, Ernst, Elias, Johannes, Emhofer, Josef, Etschmaier, Rosa, Farr, Sebastian, Girtler, Ylenia, Grigorow, Irina, Heimann, Konrad, Ihm, Ulrike, Jaros, Zdenek, Kalhoff, Hermann, Kaulfersch, Wilhelm, Kemen, Christoph, Klocker, Nina, Köster, Bernhard, Kohlmaier, Benno, Komini, Eleni, Kramer, Lydia, Neubert, Antje, Ortner, Daniel, Pescollderungg, Lydia, Pfurtscheller, Klaus, Reiter, Karl, Ristic, Goran, Rödl, Siegfried, Sellner, Andrea, Sonnleitner, Astrid, Sperl, Matthias, Stelzl, Wolfgang, Till, Holger, Trobisch, Andreas, Vierzig, Anne, Vogel, Ulrich, Weingarten, Christina, Welke, Stefanie, Wimmer, Andreas, Wintergerst, Uwe, Wüller, Daniel, Zaunschirm, Andrew, Ziuraite, Ieva, Žukovskaja, Veslava, Hibberd, Martin L., Davila, Sonia, Delany, Isabel, Schlapbach, Luregn J, Raman, Sainath, Sharp, Nathalie, Phillips, Natalie, Irwin, Adam, Balch, Ross, Harley, Amanda, Johnson, Kerry, Sever, Zoe, George, Shane, Grimwood, Keith, Snelling, Peter J, Chavan, Arjun, Kitcatt, Eleanor, Lawton, Luke, Hempenstall, Allison, Pilot, Pelista, Gibbons, Kristen S, Le Marsney, Renate, Blumenthal, Antje, Ganesamoorthy, Devika, Pardo, Carolyn, Kling, Jessica, McPherson, Stephen, MacDonald, Anna D, Bialasiewicz, Seweryn, Pham, Trang, Wilson, Clare, Sharp, Natalie, Kling, Jessica C, McPherson, Stephen J, Herberg, Jethro A, and Coin, Lachlan J M

Published
2024
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2. Bairdne : a practice-led re-imagination of harp accompaniments to Gaelic bardic poetry

Author

O'Neill, Lauren, Comer, Niall, and Melvin, Adam

Subjects
Irish traditional harp music, Recitation, Spoken word
Abstract

This thesis explores the performance of Gaelic bardic poetry and accompanying harp music in a re-imagined, contemporary traditional harping context. Offering unique insights and contributions which highlight the potential of this practice as a contemporary art form, this research explores the parameters of the connection between Gaelic bardic poetry and harp accompaniments through the medium of the harper and reciter in collaborative practice. Chapter One introduces the elite historical performance practice of Gaelic bardic poetry and harp music, and the roles of the poet and harper throughout the bardic era. Chapter Two provides an overview of this study's chaotic journey within arts practice research, and the resulting practice-led methodology adopted as a means to gain insight into the functioning role of the harper within this re-imagined, contemporary performance practice. Placing myself in the role of the harper as practitioner has changed both my perception and approach to performance, whilst also drawing attention to this novel mode of practice previously unexplored within contemporary Irish traditional harp performance. Chapters Three to Eight underline key connections between the recitation of Gaelic bardic poetry and accompanying harp music, discovered through the creation of harp accompaniments inspired by historical descriptions of this performance practice, characteristics of historical harp music and Gaelic bardic poetry itself. Chapter Nine concludes this study, which builds upon current scholarship relating to bardic performance practice, arguing the instinctive, symbiotic collaboration between harper and reciter within the creative process of practice, and revealing parameters which guide the unique intertwining of the spoken word and accompanying harp music in contemporary re-imagination.

Published
2021

3. The death of the groupie: The original mega-fan has shaped pop culture since the 1970s. But after Me Too, is there still a place for sex in rock 'n' roll?

Author

O'Neill, Lauren

Subjects
Feminism -- Forecasts and trends, Groupies -- Appreciation, Authors -- Beliefs, opinions and attitudes, Popular music -- Forecasts and trends, Market trend/market analysis, Political science, Literature/writing
Abstract

'I started with Elvis, she said, when Elvis went 'off to war' and she marked the days off one-by-one for two years on a calendar hanging in her bedroom.' So [...]

Published
2023

4. Current and ideal living arrangements and supports for Canadian adults with fetal alcohol spectrum disorder: Part II—Perspectives from caregivers.

Author

Gault, Siann, Gnat, Lauren, Fletcher, Paula C., Kirst, Maritt, O'Neill, Lauren, MacDonald, Robert, and Ninomiya, Melody E. Morton

Subjects
SAFETY, RESEARCH funding, RESIDENTIAL patterns, INTERVIEWING, STATISTICAL sampling, JUDGMENT sampling, EMOTIONS, FETAL alcohol syndrome, RESEARCH methodology, CONCEPTUAL structures, COMMUNICATION, SOCIAL support, INTERPERSONAL relations, HOUSING, CAREGIVER attitudes, ACTIVITIES of daily living
Abstract

Background: Caregivers supporting adults with fetal alcohol spectrum disorder (FASD) report concerns regarding living arrangements and services for their adult children with FASD. Best practices for living support for adults with FASD are under‐researched, and few studies have explored the experiences of caregivers whose children are adults. This study examined the perspectives of caregivers who support adults (18+) with FASD regarding: (1) current ways adults with FASD are supported with daily life activities; and (2) ideal future living arrangements and supports. Methods: This article presents findings from the perspective of caregivers who support adults with FASD, as part of a broader project involving both adults with FASD and caregivers. Semi‐structured interviews were conducted with 11 Canadian caregivers who live at home with an adult with FASD (aged 18+). Responses were examined using framework analysis, a structured approach to analyzing qualitative data. Results: Caregivers described their experiences and perspectives regarding: (1) current ways adults with FASD are supported in their daily activities; (2) strategies for successful support; (3) ideal future living arrangements and supports; and (4) concerns for the future. Notably, almost every participant raised pressing concerns regarding the future living arrangements for the person they support once they are no longer able to provide care. Conclusions: This study explores caregivers' perspectives regarding living support needed by adults with FASD, which can inform support programs and housing services. Findings demonstrate an urgent need for policy change directed toward developing available, affordable, and appropriate housing for adults with FASD. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study

Author

Levin, Michael, Coin, Lachlan, Gormley, Stuart, Hamilton, Shea, Herberg, Jethro, Hourmat, Bernardo, Hoggart, Clive, Kaforou, Myrsini, Sancho-Shimizu, Vanessa, Wright, Victoria, Abdulla, Amina, Agapow, Paul, Bartlett, Maeve, Bellos, Evangelos, Eleftherohorinou, Hariklia, Galassini, Rachel, Inwald, David, Mashbat, Meg, Menikou, Stefanie, Mustafa, Sobia, Nadel, Simon, Rahman, Rahmeen, Thakker, Clare, Bokhandi, Sumit, Power, Sue, Barham, Heather, Pathan, Nazima, Ridout, Jenna, White, Deborah, Thurston, Sarah, Faust, Saul, Patel, Sanjay, McCorkell, Jenni, Davies, Patrick, Crate, Lindsey, Navarra, Helen, Carter, Stephanie, Ramaiah, Raghu, Patel, Rekha, Tuffrey, Catherine, Gribbin, Andrew, McCready, Sharon, Peters, Mark, Hardy, Katie, Standing, Fran, O'Neill, Lauren, Abelake, Eugenia, Deep, Akash, Nsirim, Eniola, Pollard, Andrew, Willis, Louise, Young, Zoe, Royad, C, White, Sonia, Fortune, Peter Marc, Hudnott, Phil, Martinón-Torres, Federico, Salas Ellacuriaga, Antonio, Álvez González, Fernando, Barral-Arca, Ruth, Cebey-López, Miriam, Curras-Tuala, María José, García, Natalia, García Vicente, Luisa, Gómez-Carballa, Alberto, Gómez Rial, Jose, Grela Beiroa, Andrea, Justicia Grande, Antonio, Leboráns Iglesias, Pilar, Martínez Santos, Alba Elena, Martinón-Torres, Nazareth, Martinón Sánchez, José María, Morillo Gutiérrez, Beatriz, Mosquera Pérez, Belén, Obando Pacheco, Pablo, Pardo-Seco, Jacobo, Pischedda, Sara, Rivero-Calle, Irene, Rodríguez-Tenreiro, Carmen, Redondo-Collazo, Lorenzo, Serén Fernández, Sonia, Porto Silva, María del Sol, Vega, Ana, Vilanova Trillo, Lucía, Reyes, Susana Beatriz, León León, María Cruz, Navarro Mingorance, Álvaro, Gabaldó Barrios, Xavier, Oñate Vergara, Eider, Concha Torre, Andrés, Vivanco, Ana, Fernández, Reyes, Giménez Sánchez, Francisco, Sánchez Forte, Miguel, Rojo, Pablo, Ruiz Contreras, Jesús, Palacios, Alba, Epalza Ibarrondo, Cristina, Fernández Cooke, Elizabeth, Navarro, Marisa, Álvarez Álvarez, Cristina, Lozano, María José, Carreras, Eduardo, Brió Sanagustín, Sonia, Neth, Olaf, Martínez Padilla, María del Carmen, Prieto Tato, Luis Manuel, Guillén, Sara, Fernández Silveira, Laura, Moreno, David, de Groot, Ronald, van Furth, A. Marceline, van der Flier, Michiel, Boeddha, Navin Prekash, Driessen, Gertjan JA, Emonts, Marieke, Hazelzet, Jan A, Kuijpers, Taco W, Pajkrt, Dasja, Sanders, Elisabeth AM, van de Beek, Diederik, van der Ende, Arie, Philipsen, Ria LA, Adeel, Abdul OA, Breukels, Meike A, Brinkman, Danielle MC, de Korte, Carla CMM, de Vries, Esther, de Waal, Wouter J, Dekkers, Roel, Dings-Lammertink, Anouk, Doedens, Rienus A, Donker, Albertine E, Dousma, Mieke, Faber, Tina E, Gerrits, G Peter JM, Gerver, Jan AM, Heidema, Jojanneke, Homan-van der Veen, Jenneke, Jacobs, Monique AM, Jansen, Nicolaas JG, Kawczynski, Pawel, Klucovska, Kristine, Kneyber, Martin CJ, Koopman-Keemink, Yvonne, Langenhorst, Veerle J, Leusink, José, Loza, Bettina F, Merth, Istvan T, Miedema, Carien J, Neeleman, Chris, Noordzij, Jeroen G, Obihara, Charles C, van Overbeek - van Gils, A Lidy T, Poortman, Geriska H, Potgieter, Steph T, Potjewijd, Joke, Rosias, Philippe PR, Sprong, Tom, ten Tussher, Gavin W, Thio, Boony J, Tramper-Stranders, Gerdien A, van Deuren, Marcel, van der Meer, Henny, van Kuppevelt, Andre JM, van Wermeskerken, Anne-Marie, Verwijs, Wim A, Wolfs, Tom FW, Schlapbach, Luregn Jan, Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M, Heininger, Ulrich, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian, Hasters, Paul, Relly, Christa, Baer, Walter, Carrol, Enitan, Paulus, Stéphane, Frederick, Hannah, Jennings, Rebecca, Johnston, Joanne, Kenwright, Rhian, Fink, Colin G, Pinnock, Elli, Agbeko, Rachel Sarah, Anderson, Suzanne T, Secka, Fatou, Bojang, Kalifa A, Sarr, Isatou, Kebbeh, Ngange, Sey, Gibbi, Saidykhan, Momodou, Cole, Fatoumata, Thomas, Gilleh, Antonio, Martin, Zenz, Werner, Klobassa, Daniela Sabine, Binder, Alexander, Schweintzger, Nina Alexandra, Sagmeister, Manfred, Baumgart, Hinrich, Baumgartner, Markus, Behrends, Uta, Biebl, Ariane, Birnbacher, Robert, Blanke, Jan-Gerd, Boelke, Carsten, Breuling, Kai, Brunner, Jürgen, Buller, Maria, Dahlem, Peter, Dietrich, Beate, Eber, Ernst, Elias, Johannes, Emhofer, Josef, Etschmaier, Rosa, Farr, Sebastian, Girtler, Ylenia, Grigorow, Irina, Heimann, Konrad, Ihm, Ulrike, Jaros, Zdenek, Kalhoff, Hermann, Kaulfersch, Wilhelm, Kemen, Christoph, Klocker, Nina, Köster, Bernhard, Kohlmaier, Benno, Komini, Eleni, Kramer, Lydia, Neubert, Antje, Ortner, Daniel, Pescollderungg, Lydia, Pfurtscheller, Klaus, Reiter, Karl, Ristic, Goran, Rödl, Siegfried, Sellner, Andrea, Sonnleitner, Astrid, Sperl, Matthias, Stelzl, Wolfgang, Till, Holger, Trobisch, Andreas, Vierzig, Anne, Vogel, Ulrich, Weingarten, Christina, Welke, Stefanie, Wimmer, Andreas, Wintergerst, Uwe, Wüller, Daniel, Zaunschirm, Andrew, Ziuraite, Ieva, Žukovskaja, Veslava, Salas, Antonio, Herberg, Jethro A, Boeddha, Navin P, Klobassa, Daniela S, Paulus, Stephane, Schlapbach, Luregn J, Driessen, Gertjan J, Carrol, Enitan D, and Van der Flier, Michiel

Published
2018
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8. Reducing the Influence of Perceived Stress on Subjective Well-Being of Student Veterans With and Without Disabilities: The Protective Role of Positive Traits and Social Support.

Author

Umucu, Emre, Lee, Beatrice, Berwick, Abigail, O'Neill, Lauren Elizabeth, Chan, Fong, and Chen, Xiangli

Subjects
WELL-being, COLLEGE students, RESEARCH, SOCIAL support, CONFIDENCE intervals, CROSS-sectional method, SELF-evaluation, HOPE, STRESS management, DESCRIPTIVE statistics, FACTOR analysis, RESEARCH funding, PEOPLE with disabilities, VETERANS, STUDENT attitudes, STATISTICAL correlation, DATA analysis software, PSYCHOLOGICAL stress, PSYCHOLOGICAL resilience
Abstract

The transition from the regimented environment of military service to a less structured college lifestyle can be stressful for student veterans with and without disabilities, which highlights the importance of exploring protective person-environmental contextual factors that can help student veterans with and without disabilities manage their stress effectively, leading to enhanced well-being. The purpose of this cross-sectional correlational design study was to examine the role of positive person-environment contextual factors, including hope, resilience, core self-evaluations, and social support, to reduce the influence of perceived stress on the subjective well-being (SWB) of student veterans with and without disabilities. The sample consisted of 205 student veterans (71.7% males; 80.5% White; Mage = 29.32; 39% with service-connected disability). Findings suggested that core self-evaluations and social support partially mediated the relationship between perceived stress and SWB in student veterans with and without disabilities. Implications for clinicians, university counselors, and university staff are also discussed. [ABSTRACT FROM AUTHOR]

Published
2023
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10. Five-Minutes of Mindfulness: Utilizing Guided Meditation to Supplement ADHD Treatment Plans in Adolescents

Author

O'Neill, Lauren Louise

Abstract

Background: ADHD can impair functioning in multiple areas (i.e., social relationships and academic/work productivity); pharmacological, behavioral, or combination treatment is recommended given its association with long-term adverse outcomes. Due to an individual’s varying experience with a treatment’s benefits or side-effects, a multitude of options should be available. One newer behavioral treatment option is mindfulness-based interventions (MBIs).Objectives: The objectives of this project were to pilot implementation of an MBI as a supplemental treatment in patients 12 to 19 years old with ADHD at a pediatric behavioral health clinic and to observe a decrease in their ADHD symptom severity and insomnia severity.Methods: The nurse practitioners and student investigator implemented the MBI during an office visit. Participants were educated about MBIs then instructed to practice a five-minute guided meditation daily for four weeks. Impact was measured by comparing pre- and post-intervention NICHQ Vanderbilt Symptom Scale Scores and Pediatric Insomnia Severity Index (PISI) scores along with analyzing patient evaluation feedback. Knowledge for future project sustainability and expansion was generated from provider, patient, and family feedback. Results: There was an observed 41% decrease in Vanderbilt total symptom scores, 60% decrease in hyperactivity/impulsivity symptoms, and 27% decrease in inattentive symptoms. The PISI scores decreased by 53%, indicating a positive impact on sleep quality and habits. Participants largely believed the guided meditation had a positive impact on stress, relationships, and everyday life; all planned on continuing to use the guided meditation. The impact of the global COVID19 pandemic, an unexpected high rate of refusal or resistance to participation, the high percentage of telehealth virtual visits, and a failure to complete the intervention all contributed to a smaller than anticipated sample size (n = 3). Conclusion: Despite the unexpectedly small sample size, the results demonstrate that using an MBI, such as a guided meditation, as a treatment supplement can positively impact ADHD symptoms and sleep; patients also perceive a positive effect on stress, relationships, and everyday life. This project also identified potential barriers and facilitators to widescale MBI implementation with this population; this knowledge will inform future efforts of sustainability and expansion.

Published
2021
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12. The impact of Daubert in forensic science.

Author

Fradella, Henry F., O'Neill, Lauren, and Fogarty, Adam

Subjects
Forensic sciences -- Evaluation, Evidence, Scientific -- Laws, regulations and rules, Evidence, Expert -- Laws, regulations and rules, Daubert v. Merrell Dow Pharmaceuticals, Inc. (509 U.S. 579 (1993)), Government regulation
Published
2004

14. The golden age of Wags: The Coleen Rooney and Rebekah Vardy spat saw the social media age collide with a bygone era of tabloid celebrity

Author

O'Neill, Lauren

Subjects
Social media -- Usage, Celebrities -- Beliefs, opinions and attitudes, Scandals -- Forecasts and trends, Shock, Financial markets, Market trend/market analysis, Literature/writing, Political science
Abstract

In a shock similar in size and scale to the one experienced by the stock market in 2008, two eras collided on 9 October. Coleen Rooney, wife of former Manchester [...]

Published
2019

15. Identification of regulatory variants associated with genetic susceptibility to meningococcal disease

Author

Borghini, Lisa, Png, Eileen, Binder, Alexander, Wright, Victoria J, Pinnock, Ellie, de Groot, Ronald, Hazelzet, Jan, Emonts, Marieke, Van der Flier, Michiel, Schlapbach, Luregn J, Anderson, Suzanne, Secka, Fatou, Salas, Antonio, Fink, Colin, Carrol, Enitan D, Pollard, Andrew J, Coin, Lachlan J, Kuijpers, Taco W, Martinon-Torres, Federico, Zenz, Werner, Levin, Michael, Hibberd, Martin L, Davila, Sonia, Gormley, Stuart, Hamilton, Shea, Herberg, Jethro, Hourmat, Bernardo, Hoggart, Clive, Kaforou, Myrsini, Sancho-Shimizu, Vanessa, Abdulla, Amina, Agapow, Paul, Bartlett, Maeve, Bellos, Evangelos, Eleftherohorinou, Hariklia, Galassini, Rachel, Inwald, David, Mashbat, Meg, Menikou, Stefanie, Mustafa, Sobia, Nadel, Simon, Rahman, Rahmeen, Thakker, Clare, Bokhandi, S, Power, Sue, Barham, Heather, Pathan, N, Ridout, Jenna, White, Deborah, Thurston, Sarah, Faust, S, Patel, S, McCorkell, Jenni, Davies, P, Cratev, Lindsey, Navarra, Helen, Carter, Stephanie, Ramaiah, R, Patel, Rekha, Tuffrey, Catherine, Gribbin, Andrew, McCready, Sharon, Peters, Mark, Hardy, Katie, Standing, Fran, O'Neill, Lauren, Abelake, Eugenia, Deep, Akash, Nsirim, Eniola, Willis, Louise, Young, Zoe, Royad, C, White, Sonia, Fortune, PM, Hudnott, Phil, Alvez Gonzalez, Fernando, Barral-Arca, Ruth, Cebey-Lopez, Miriam, Jose Curras-Tuala, Maria, Garcia, Natalia, Garcia Vicente, Luisa, Gomez-Carballa, Alberto, Gomez Rial, Jose, Grela Beiroa, Andrea, Justicia Grande, Antonio, Leborans Iglesias, Pilar, Martinez Santos, Alba Elena, Martinon-Torres, Nazareth, Martinon Sanchez, Jose Maria, Mosquera Perez, Belen, Obando Pacheco, Pablo, Pardo-Seco, Jacobo, Pischedda, Sara, Rivero Calle, Irene, Rodriguez-Tenreiro, Carmen, Redondo-Collazo, Lorenzo, Seren Fernandez, Sonia, Porto Silva, Maria del Sol, Vega, Ana, Beatriz Reyes, Susana, Leon Leon, Maria Cruz, Navarro Mingorance, Alvaro, Gabaldo Barrios, Xavier, Onate Vergara, Eider, Concha Torre, Andres, Vivanco, Ana, Fernandez, Reyes, Gimenez Sanchez, Francisco, Sanchez Forte, Miguel, Rojo, Pablo, Ruiz Contreras, J, Palacios, Alba, Navarro, Marisa, Alvarez Alvarez, Cristina, Jose Lozano, Maria, Carreras, Eduardo, Brio Sanagustin, Sonia, Neth, Olaf, Martinez Padilla, Ma del Carmen, Prieto Tato, Luis Manuel, Guillen, Sara, Fernandez Silveira, Laura, Moreno, David, van Furth, AM Tutu, van der Flier, M, Boeddha, NP, Driessen, GJA, Pajkrt, D, Sanders, EAM, van de Beek, D, van der Ende, A, Philipsen, HLA, Adeel, AOA, Breukels, MA, Brinkman, DMC, de Korte, CCMM, de Vries, E, de Waal, WJ, Dekkers, R, Dings-Lammertink, A, Doedens, RA, Donker, AE, Dousma, M, Faber, TE, Gerrits, GPJM, Gerver, JAM, Heidema, J, Homan-van der Veen, J, Jacobs, MAM, Jansen, NJG, Kawczynski, P, Klucovska, K, Kneyber, MCJ, Koopman-Keemink, Y, Langenhorst, VJ, Leusink, J, Loza, BF, Merth, IT, Miedema, CJ, Neeleman, C, Noordzij, JG, Obihara, CC, van Overbeek-van Gils, ALT, Poortman, GH, Potgieter, ST, Potjewijd, J, Rosias, PPR, Sprong, T, ten Tussher, GW, Thio, BJ, Tramper-Stranders, GA, van Deuren, M, van der Meer, H, van Kuppevelt, AJM, van Wermeskerken, AM, Verwijs, WA, Wolfs, TFW, Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Giannoni, Eric, Stocker, Martin, Posfay-Barbe, Klara M, Heininger, Ulrich, Bernhard-Stirnemann, Sara, Niederer-Loher, Anita, Kahlert, Christian, Hasters, Paul, Relly, Christa, Baer, Walter, Paulus, Stephane, Frederick, Hannah, Jennings, Rebecca, Johnston, Joanne, Kenwright, Rhian, Agbeko, Rachel, Bojang, Kalifa, Sarr, Isatou, Kebbeh, Ngane, Sey, Gibbi, Saidykhan, Momodou, Cole, Fatoumatta, Thomas, Gilleh, Antonio, Martin, Walcher, Wolfgang, Geishofer, Gotho, Klobassa, Daniela, Martin, Mueller, Pfurtscheller, Klaus, Reiter, Karl, Roedl, Siegfried, Zobel, Gerfried, Zoehrer, Bettina, Toepke, Baerbel, Fucik, Peter, Gabriel, Markwart, Penzien, Johann M, Diab, Gedeon, Miething, Robert, Deeg, KH, Hammer, Jurg, Varnholt, Verena, Schmidt, Andreas, Bindl, Lutz, Sillaber, Ursula, Huemer, Christian, Meier, Primrose, Simic-Schleicher, G, Markart, Markus, Pfau, Eberhard, Broede, Hans, Ausserer, Bernd, Kalhoff, Hermann, Arpe, Volker, Schweitzer-Krantz, Susanne, Kasper, Johannes-Martin, Loranth, Kathrin, Bittrich, Hans J, Simma, Burkhard, Klinge, Jens, Fedlmaier, Michael, Weigand, Nicola, Herting, Egbert, Grube, Regina, Fusch, Christoph, Gruber, Alois, Schimmel, Ulf, Knaufer-Schiefer, Suzanne, Laessig, Wolfgang, Hennenberger, Axel, von der Wense, Axel, Tillmann, Roland, Schwarick, Juergen, Sitzmann, Friedrich C, Streif, Werner, Mueller, Herbert, Kurnik, Peter, Groneck, Peter, Weiss, Ute, Groeblacher-Roth, Helene, Bensch, Juergen, Moser, Reinhard, Schwarz, Rudolf, Lenz, Kurt, Hofmann, Thomas, Goepel, Wolfgang, Schulz, Dietrich, Berger, Thomas, Hauser, Erwin, Foerster, Kai Martin, Peters, Jochen, Nicolai, T Homas, Kumlien, Bjoern, Beckmann, Regina, Seitz, Christiane, Hueseman, D, Schuermann, Roland, Ta, Van Hop, Weikmann, Eckart, Evert, W, Hautz, Juergen, Seidenberg, Juergen, Wocko, Lucia, Luigs, Petra, Reiter, Hans-Ludwig, Quietzach, J, Koenig, Michael, Herrmann, Johanna, Mitter, Horst, Seidler, Ekkehard, Maak, Bernhard, Sperl, Wolfgang, Zwiauer, Karl, Meissl, Manfred, Koch, Reinhard, Cremer, Manfred, Breuer, HA, Goerke, W, Nossal, Robert, Pernice, Walter, Brangenberg, Ralf, Salzer, Hans R, Koch, Hartmut, Schaller, Gerhard, Paky, Franz, Strasser, Friedrich, Eitelberger, Franz, Sontheimer, D, Lischka, Andreas, Kronberger, Martina, Dilch, Alfred, Scheibenpflug, Christian, Bruckner, Robert, Mahler, Klaus, Runge, Klaus, Kunze, Wolfgang, Schermann, Peter, Consortium, EUCLIDS, European Commission, Meningitis Research Foundation, National Institute for Health Research (UK), Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne Hospitals NHS Foundation Trust, Instituto de Salud Carlos III, Xunta de Galicia, Wyeth Farma, Fundación Instituto de Investigación Sanitaria de Santiago de Compostela, Novartis, Swiss National Science Foundation, Swiss Society of Intensive Care Medicine, Gottfried und Julia Bangerter-Rhyner-Stiftung, Vinetum and Borer Foundation, Foundation for the Health of Children and Adolescents, Austrian National Bank, University of Zurich, Borghini, Lisa, Universidade de Santiago de Compostela. Departamento de Ciencias Forenses, Anatomía Patolóxica, Xinecoloxía e Obstetricia, e Pediatría, Png, Eileen [0000-0001-5586-6395], Wright, Victoria J [0000-0001-7826-1516], Schlapbach, Luregn J [0000-0003-2281-2598], Salas, Antonio [0000-0002-2336-702X], Martinon-Torres, Federico [0000-0002-9023-581X], Apollo - University of Cambridge Repository, ARD - Amsterdam Reproduction and Development, AII - Infectious diseases, Paediatric Infectious Diseases / Rheumatology / Immunology, Neurology, ANS - Neuroinfection & -inflammation, Medical Microbiology and Infection Prevention, Pediatrics, Public Health, Posfay Barbe, Klara, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), APH - Aging & Later Life, Amsterdam Reproduction & Development (AR&D), and Pediatric surgery

Subjects
0301 basic medicine, Candidate gene, Hypopharyngeal Neoplasms / microbiology, Meningococcal Infections / microbiology, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], MathematicsofComputing_GENERAL, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], lcsh:Medicine, Neisseria meningitidis, Regulatory Sequences, Nucleic Acid, Cohort Studies, 0302 clinical medicine, ComputingMethodologies_SYMBOLICANDALGEBRAICMANIPULATION, Hypopharyngeal Neoplasms / pathology, BINDING, Tumor Cells, Cultured, lcsh:Science, Genetics, Multidisciplinary, ddc:618, Cultured, TheoryofComputation_GENERAL, High-Throughput Nucleotide Sequencing, Genomics, Phenotype, 3. Good health, ddc, Tumor Cells, Multidisciplinary Sciences, GENOME, Science & Technology - Other Topics, Neisseria meningitidis / isolation & purification, Single-nucleotide polymorphism, 610 Medicine & health, KAPPA-B, Biology, Hypopharyngeal Neoplasms / genetics, Polymorphism, Single Nucleotide, Article, Meningococcal Infections / epidemiology, 03 medical and health sciences, SEQUENCE VARIATION, Genetic predisposition, Journal Article, Humans, Meningitis, Meningococcal Infections / genetics, Genetic Predisposition to Disease, Nucleic Acid, Polymorphism, General, Gene, Genotyping, Neisseria meningitidis / genetics, Genetic Association Studies, Genetic association, Genetic association study, 1000 Multidisciplinary, Science & Technology, Hypopharyngeal Neoplasms, genetic variants, meningococcal disease, lcsh:R, Single Nucleotide, EUCLIDS consortium, Gene regulation, Meningococcal Infections, 030104 developmental biology, 10036 Medical Clinic, Case-Control Studies, lcsh:Q, Software_PROGRAMMINGLANGUAGES, Regulatory Sequences, 030217 neurology & neurosurgery
Abstract

EUCLIDS consortium., Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions relevant for the phenotype studied. We applied this method to meningococcal disease susceptibility, using the DNA binding pattern of RELA – a NF-kB subunit, master regulator of the response to infection – under bacterial stimuli in nasopharyngeal epithelial cells. We designed a custom panel to cover these RELA binding sites and used it for targeted sequencing in cases and controls. Variant calling and association analysis were performed followed by validation of candidate polymorphisms by genotyping in three independent cohorts. We identified two new polymorphisms, rs4823231 and rs11913168, showing signs of association with meningococcal disease susceptibility. In addition, using our genomic data as well as publicly available resources, we found evidences for these SNPs to have potential regulatory effects on ATXN10 and LIF genes respectively. The variants and related candidate genes are relevant for infectious diseases and may have important contribution for meningococcal disease pathology. Finally, we described a novel genetic association approach that could be applied to other phenotypes., This work has been partially funded by the European Seventh Framework Programme for Research and Technological Development (FP7) under EUCLIDS Grant Agreement No. 279185. The UK meningococcal cohort was established with support from Meningitis Research Foundation through grants to Imperial College London. The Research from Newcastle partners was supported by the National Institute for Health Research Newcastle Biomedical Research Centre based at Newcastle Hospitals NHS Foundation Trust and Newcastle University. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. The ESIGEM Research group activities were supported by grants from Instituto de Salud Carlos III (Proyecto de Investigación en Salud, Acción Estratégica en Salud: proyecto GePEM PI16/01478) (A.S.); Consellería de Sanidade, Xunta de Galicia (RHI07/2-intensificación actividad investigadora, PS09749 and 10PXIB918184PR), Instituto de Salud Carlos III (Intensificación de la actividad investigadora 2007–2016), Convenio de colaboración de investigación (Wyeth España-Fundación IDICHUS 2007–2011), Convenio de colaboración de investigación (Novartis España-Fundación IDICHUS 2010–2011), Fondo de Investigación Sanitaria (FIS; PI070069/PI1000540) del plan nacional de I + D + I and ‘fondos FEDER’ (F.M.T.). The Swiss Pediatric Sepsis study was funded by grants from the Swiss National Science Foundation (342730_153158/1), the Swiss Society of Intensive Care, the Bangerter Foundation, the Vinetum and Borer Foundation, and the Foundation for the Health of Children and Adolescents. The Western Europe Meningococcal Study was supported by grants no 8842, 10112 and 12710 of the Oesterreichische Nationalbank (Austria), grants A3-16.K-8/2008-11 and A3-16.K-8/2006–9 of the Department for Science and Research of the Styrian federal government (Austria) and the non for profit association ‘In Vita’, Graz (Austria).

Published
2019
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17. Dickinson College Welcomes Class of 2023 During Convocation Ceremony

Author

O'Neill, Lauren Davidson; Video By Joe

Subjects
Creativity -- Rites, ceremonies and celebrations, Mayors, News, opinion and commentary, Sports and fitness, Dickinson College -- Rites, ceremonies and celebrations
Abstract

Byline: Lauren Davidson; video by Joe O'Neill Class of 2023 encouraged to begin journey as Dickinsonians with 'courage and creativity' by Lauren Davidson; video by Joe O'Neill On Sunday, Sept. [...]

Published
2019

18. Comparing clinical acne vulgaris severity to adolescent and parent perceptions of acne severity and impact on quality of life.

Author

Sadowsky, Lauren M., Yang, Connie Y., Sorrell, Jennifer, Bayers, Stephanie, O'Neill, Lauren B., Chamlin, Sarah L., and Schlosser, Bethanee J.

Subjects
ACNE, QUALITY of life, LIKERT scale, RANK correlation (Statistics)
Abstract

Background/Objectives: Little research has compared clinician acne severity assessment with either adolescent‐ or parent‐rated scales of acne severity or impact on quality of life (QOL). We sought to assess how adolescents and their parents perceive the severity and impact of acne on the adolescent's QOL and correlate this with clinical severity. Methods: Each adolescent and a parent completed a validated QOL survey regarding the adolescent's acne and rated the adolescent's acne severity and QOL impact using a Likert scale. Clinicians assessed the adolescent's acne using a standardized acne severity scale. Statistical analysis compared adolescent scores with respective parent scores or with clinician assessment using a paired t test or Spearman rank‐order correlation test. Results: The Likert impact score more accurately reflected acne impact on QOL for adolescents than for parents when considering the validated QOL survey as the gold standard (r2 =.56 vs r2 =.36). Likert scores for adolescents and parents were weakly correlated for acne severity but not for acne QOL impact (r2 =.36 vs r2 =.18). Correlations of acne severity scores between clinician and either adolescent or parent were weak. Conclusions: Parents and adolescents are in relative agreement regarding acne severity and QOL impact. However, parent and adolescent perceptions are disparate from clinician acne assessment. It is important that physicians identify and consider adolescent and parent perceptions in addition to clinical assessment to better inform the approach to acne management. [ABSTRACT FROM AUTHOR]

Published
2020
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19. Admitted Student Open House Draws Record Attendance

Author

O'Neill, Lauren Davidson; Video By Joe

Subjects
College admissions, News, opinion and commentary, Sports and fitness
Abstract

Byline: Lauren Davidson; video by Joe O'Neill From record application numbers to record open house attendence, the class of 2022 is making its mark by Lauren Davidson; video by Joe [...]

Published
2018

20. Dickinson College Community Celebrates and Congratulates Class of 2022

Author

O'Neill, Lauren Davidson; Video By Joe

Subjects
Universities and colleges, News, opinion and commentary, Sports and fitness
Abstract

Byline: Lauren Davidson; video by Joe O'Neill A variety of events near and far find Dickinsonians celebrating and congratulating students admitted to class of 2022 by Lauren Davidson; video by [...]

Published
2018

22. Educational opportunities within correctional institutions: does facility type matter?

Author

O'Neill, Lauren, MacKenzie, Doris Layton, and Bierie, David M.

Subjects
Education of prisoners -- Comparative analysis, Equivalency tests -- Comparative analysis, Correctional institutions -- Comparative analysis, Social sciences
Abstract

A study examining differences in education provided at a Boot Camp and a traditional facility is conducted. Findings suggest that inmates are more successful in obtaining a General Equivalency Diploma at a Boot camp due to its therapeutic environment.

Published
2007

24. Efficacy of a Micro-Prompting Technology in Reducing Support Needed by People With Severe Acquired Brain Injury in Activities of Daily Living: A Randomized Control Trial.

Author

O'Neill, Brian, Best, Catherine, O'Neill, Lauren, Ramos, Sara D. S., and Gillespie, Alex

Abstract

Objective: To evaluate the effectiveness of an automated interactive prompting technology in supporting the morning routine of persons with acquired brain injury. The morning routine included maintaining personal hygiene and dressing. Setting: An inpatient neurorehabilitation hospital. Participants: Persons with acquired brain injury who required prompting when following their morning routine (n = 24), but were not limited by physical disability or dysphasia, took part in the study. Participants (67% with traumatic brain injury) had impairment on indices of memory and executive function. Design: A randomized control trial evaluated the effect of an automated interactive micro-prompting device on the number of prompts by trained staff required for successful completion of the morning routine. Main Measures: Study-specific checklists assessed sequence performance, errors, and verbal prompts required over baseline, rehabilitation as usual, intervention, and return to baseline conditions. Results: The intervention significantly reduced the support required to complete the task compared with usual rehabilitation. Conclusions: Micro-prompting technology is an effective assistive technology for cognition, which reduces support needs in people with significant cognitive impairments. [ABSTRACT FROM AUTHOR]

Published
2018
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26. When you do need two eye drops

Author

O'Neill, Lauren

Subjects
Ophthalmic solutions -- Dosage and administration, Consumer news and advice
Published
2007

27. Automated prompting technologies in rehabilitation and at home.

Author

O'Neill, Brian, Best, Catherine, Gillespie, Alex, and O'Neill, Lauren

Subjects
PROMPTS (Psychology), ACTIVITIES of daily living, COGNITION disorder patients, MOTIVATION (Psychology), MEDICAL rehabilitation
Abstract

Purpose – The purpose of this paper is to test the efficacy of an interactive verbal prompting technology (Guide) on supporting the morning routine. Data have already established the efficacy of such prompting during procedural tasks, but the efficacy of such prompting in tasks with procedural and motivational elements remains unexamined. Such tasks, such as getting out of bed in the morning and engaging in personal care, are often the focus of rehabilitation goals. Design/methodology/approach – A single-n study with a male (age 61) who had severe cognitive impairment and was having trouble completing the morning routine. An A-B-A′-B′-A'-B' design was used, with the intervention phase occurring both in an in-patient unit (B, B′) and in the participant's own home (B'). Findings – Interactive verbal prompting technology (Guide) significantly reduced support worker prompting and number of errors in the in-patient setting and in the participant's own home. Research limitations/implications – The results suggest that interactive verbal prompting can be used to support motivational tasks such as getting out of bed and the morning routine. This study used a single subject experimental design and the results need to be confirmed in a larger sample. Originality/value – This is the first report of use of interactive verbal prompting technology to support rehabilitation of a motivational task. It is also the first study to evaluate Guide in a domestic context. [ABSTRACT FROM AUTHOR]

Published
2013
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29. From the Legal Literature.

Author

O'Neill, Lauren and Fradella, Henry F.

Abstract

The article discusses the prosecutorial discretion in capital charging. It explains the role of the prosecutor in the criminal justice system. It discusses the United States Attorney's Manual (USAM) which sets forth guidelines for federal prosecutors in an attempt to secure consistency within the Department of Justice.

Published
2008

30. A Small Public Library and Its Community: Case Study of Churchill County Library.

Author

O'Neill, Lauren

Subjects
*FINANCING of public libraries, *LIBRARY finance, *LIBRARIES & community
Abstract

Presents a case study on the financial support and improvements in services at the Churchill County library in Fallon, Nevada. Fund sources of public libraries; Background of the Churchill County library; Missions and roles of the public library; References services available to the community; Expansion of its services.

Published
2005

31. Expanding the Impact of Peer Networks: Pathways to Turning Points.

Author

O'Neill, Lauren

Subjects
LIFE, ACTIVITIES of daily living, TEENAGERS, CRIMES against youth, AGE groups, CRIME
Abstract

Recent research shows that experiencing certain life events, often called "turning points" (e.g. marriage, employment, and education), during times of transition can increase the likelihood of desistance. Thus far, research on turning points has focused on the ability of life events to predict stability and change in criminal activity and assumes that who experiences them is a mere reflection of an individual's underlying propensity to select into these conventional activities. The current research views turning points as outcome variables, recognizing that people do not experience these social events randomly. Using the National Longitudinal Study of Adolescent Health, it seeks to determine what factors might influence whether or not people participate in these turning points, placing particular attention on the role of adolescent peer networks. Arguing that peers in adolescence are exogenous to turning points in young adulthood, this research will: provide theoretical insight on which factors promote social events that spark the desistance process; further articulate the role of delinquent peer networks by investigating how pervasive their importance is over the criminal career; and discuss policy implications that may result from this empirical investigation. ..PAT.-Unpublished Manuscript [ABSTRACT FROM AUTHOR]

Published
2007

32. Remembering today what we learned yesterday: Self-control and deviant peer network structure.

Author

O'Neill, Lauren and McGloin, Jean

Subjects
CRIMINOLOGY, DEVIANT behavior, AGE groups, SOCIAL networks, SELF-control in adolescence, PUBLIC opinion, SOCIAL sciences
Abstract

The deviant peer group remains one of the strongest and most consistent correlates of delinquency across a host of methodological specifications. Recent research has moved past investigations of the simple presence or abscence of such peers and has shifted focus to various characteristics of the delinquent peer group. For example, Haynie (2001) adopted a network perspective and found that structural characteristics (e.g., density, centrality, and popularity) conditioned the impact of deviant peers on delinquency. Unfortunately, these recent investigations have ignored the potential role of self-control. Using longitudinal data on a sample of nationally representative adolescents, this investigation addresses whether the structure of delinquent peer networks still "matters" in the context of self-control. In the end, it will provide a commentary on the potential theoretical compatibility - or lack thereof - of learning and control theories when considering the facets of delinquent social networks in criminology. ..PAT.-Unpublished Manuscript [ABSTRACT FROM AUTHOR]

Published
2006

33. Situational crime prevention in schools: An effective practice or wasting resources?

Author

O'Neill, Lauren and McGloin, Jean

Subjects
CRIME prevention, SCHOOL administration, SCHOOL violence, CRIMINOLOGY, CRIMES against students, SOCIAL problems
Abstract

Situational crime prevention (SCP) techniques have proven successful in a variety of spheres. Even so, one setting that has increasingly relied on such tactics to control crime, namely schools, has not been subject to much evaluation. Given the pervasiveness of this trend, as well as the associated costs, this is a clear void in need of research. Using a cross-sectional, nationally representative sample of schools, this paper investigates the efficacy of a variety of SCP tactics with regard to numerous crime outcomes, net of statistical controls. The findings hold implications for both theory and policy. [ABSTRACT FROM AUTHOR]

Published
2005

34. YOUR letters.

Author

Alderson, Michelle, Pearce, Leanne, and O'Neill, Lauren

Subjects
LETTERS to the editor, PACKAGING, MANUFACTURING processes, CREDIT cards, EYE care
Abstract

Several letters to the editor are presented including one which discusses the amount of energy involved and carbon dioxide produced in the manufacture and recycling of packaging, another which expresses gratitude for information provided regarding a request for a refund of the late payment fee charged to her credit card, and one in response to the article "Save on Eyedrops" in the June 2007 issue.

Published
2007

36. Liquid Structure of Ionic Liquids with [NTf 2 ] - Anions, Derived from Neutron Scattering.

Author

McGrogan A, Lafferty J, O'Neill L, Brown L, Young JM, Goodrich P, Muldoon MJ, Moura L, Youngs S, Hughes TL, Gärtner S, Youngs TGA, Holbrey JD, and Swadźba-Kwaśny M

Abstract

The liquid structure of three common ionic liquids (ILs) was investigated by neutron scattering for the first time. The ILs were based on the bis(trifluoromethanesulfonyl)imide anion, abbreviated in the literature as [NTf 2 ] - or [TFSI] - , and on the following cations: 1-ethyl-3-methylimidazolium, [C 2 mim] + ; 1-decyl-3-methylimidazolium, [C 10 mim] + ; and trihexyl(tetradecyl)phosphonium, [P 666,14 ] + . Comparative analysis of the three ILs confirmed increased size of nonpolar nanodomains with increasing bulk of alkyl chains. It also sheds light on the cation-anion interactions, providing experimental insight into strength, directionality, and angle of hydrogen bonds between protons on the imidazolium ring, as well as H-C-P protons in [P 666,14 ] + , to oxygen and nitrogen atoms in the [NTf 2 ] - . The new Dissolve data analysis package enabled, for the first time, the analysis of neutron scattering data of ILs with long alkyl chains, in particular, of [P 666,14 ][NTf 2 ]. Results generated with Dissolve were validated by comparing outputs from three different models, starting from three different sets of cation charges, for each of the three ILs, which gave convergent outcomes. Finally, a modified method for the synthesis of perdeuterated [P 666,14 ][NTf 2 ] has been reported, with the aim of reporting a complete set of synthetic and data processing approaches, laying robust foundations that enable the study of the phosphonium ILs family by neutron scattering.

Published
2024
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