43 results on '"Ndiaye, Moustapha"'
Search Results
2. Generalized dystonia following resuscitation from a cardiac arrest: a case report and review of the literature
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Mbodji, Ahmadou Bamba, Fall, Maouly, Gaye, Ndiaga Matar, Ka, Mamadou, Dione, Jean Claude, Ndiaye, Moustapha, and Diop, Amadou Gallo
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- 2023
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3. Epilepsy and stigma in Africa: Viewpoint of healthcare professionals and combat strategies
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Agbetou, Méndinatou, Camara, Ibrahima François, Diallo, Lansana Laho, Soumah, Almamy S, Constant, Adrien, Djibo, Fatima H, Lamino, Ibrahim, Maiga, Youssoufa, Koné, Zeinab, Diagana, Mouhamadou, Hamadi, Hamadi, Ibrahim, Eetedal, John, Jabang, Ndiaye, Moustapha, Diarra, Eve, Foksouma, Sakadi, Dakissia, Kamis, Millogo, Athanase, Moussavou, Cédric, Daniel, Gams Massi, Razafimahefa, Julien, Dorée, Augustia, Mbelesso, Pascal, Mwendaweli, Naluca, and Kissani, Najib
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- 2023
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4. Neuromyelitis optica spectrum disorders (NMO-SD) in a Sub-Saharan Africa country: A preliminary study of sixteen Senegalese cases
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Gaye, Ndiaga Matar, Fall, Maouly, Diop, Alassane Mamadou, Dadah, Samy Mohamed Lemine, Ka, Mamadou, Cissé, Ousmane, Diagne, Ngor Side, Diop-Sène, Marième Soda, Sow, Adjaratou Dieynabou, Basse-Faye, Anna Modji, Sarr, Mamadou Moustapha, Touré, Kamadore, Seck, Lala Bouna, Ndiaye, Moustapha, and Diop, Amadou Gallo
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- 2019
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5. A Case of Rosai-Dorfman Disease Successfully Treated by Corticotherapy.
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Diallo, Alioune Badara, Ndiaye, Moustapha, Seck, Moussa, Keita, Mohamed, Bousso, Elimane Seydi, Touré, Sokhna Aissatou, Faye, Blaise Félix, and Diop, Saliou
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NON-langerhans-cell histiocytosis , *TREATMENT effectiveness , *SYMPTOMS , *PHYSICIANS , *RARE diseases - Abstract
Rosai-Dorfman disease (RDD) is a benign histiocytic proliferation that results in nodal and extranodal involvements. It is a rare disease, with fewer than 1,000 cases reported in the literature, which explains its lack of knowledge by physicians and the lack of codified therapeutic strategies. We report the case of an 8-year-old girl who presented a rapidly progressive cervical lymph node mass; the diagnosis of RDD was made based on histology and immunohistochemistry. The patient was treated with oral corticosteroids at a dose of 1 mg/kg/d with a favorable outcome and no recurrence after one year of follow-up. This observation illustrates the clinical presentation and diagnosis of this rare clinicopathological entity. The prognosis and treatment options are also discussed. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Choree de Sydenham au centre hospitalier national d’enfants Albert Royer : Aspects epidemiologiques, cliniques et paracliniques.: Sydenham's chorea at the albert royer national children's hospital : Epidemiological, clinical and paraclinical aspects
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Mbaye, Khalifa Ababacar, Diop-Sene, Marième Soda, Diagne, Rokhaya, Kane, Fatou, Mbodji, Ahmadou Bamba, Touré, Kamadore, Ndiaye, Moustapha, and Diop, Amadou Gallo
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chorée Sydenham, enfants, Sénégal ,Sydenham chorea, children, Senegal - Abstract
DescriptionLa chorée fait partie des syndromes hyperkinétiques des mouvements anormaux avec une prévalence de 5% de tous les mouvements anormaux. Les étiologies sont multiples et dominées par la chorée de Sydenham dans les pays sous-développés.ObjectifL’objectif de notre étude était de caractériser les aspects épidémiologiques, cliniques, paracliniques, étiologiques, thérapeutiques et évolutifs des enfants suivis pour chorée de Sydenham à l’unité neuropédiatrique du centre hospitalier national d’enfant Albert Royer.Patients et méthodesIl s’agissait d’une étude rétrospective et descriptive allant de janvier 2005 à janvier 2019 qui s’est déroulée à l’unité de neurologie pédiatrique du Centre National Hospitalier d’Enfants Albert Royer (CNHEAR) chez les enfants diagnostiqués de chorée de Sydenham et dont l’âge était inférieur ou égal à 16 ans.RésultatsEn 14 ans, nous avons colligé 11 enfants diagnostiqués de chorée de Sydenham dont 8 filles. L’âge moyen des enfants était de 9,45 ans. Les signes extra neurologiques étaient les cardiopathies rhumatismales et les arthralgies. Tous les patients ont bénéficié de neuroleptique (halopéridol) et l’évolution était favorable chez 90,90% des enfants.ConclusionLes chorées représentent une symptomatologie peu fréquente dans notre contexte. La chorée de Sydenham est la forme la plus représentée des chorées aigues infectieuses de l’enfant. Le traitement par l’halopéridol garde toute son efficacité dans le traitement symptomatique de ces chorées. DescriptionChorea is one of the hyperkinetic abnormal movements’ syndromes with a prevalence of 5% of all abnormal movements. The etiologies are multiple and dominated by Sydenham’s chorea in underdeveloped countries.PurposeThe objective of our study was to characterize the epidemiological, clinical, paraclinical, etiological, therapeutic and evolutionary aspects of children followed for Sydenham’s chorea at the pediatric neurology unit of the Albert Royer National Children’s Hospital.Patients and methodsThis was a retrospective and descriptive study from January 2005 to January 2019 which took place at the pediatric neurology unit of the Albert Royer National Children’s Hospital in children diagnosed with Sydenham’s chorea and whose age was less than or equal to 16 years.ResultsWithin 14 years, we have collected 11 children diagnosed with Sydenham’s chorea including 8 girls and an average age of 9.45 years. The extra neurological signs were rheumatic heart disease and arthralgia. All patients received neuroleptic (haloperidol) and the outcome was favorable in 90.90% of the children.ConclusionChorea represent an uncommon symptomatology in our context Sydenham’s chorea is the most common form of acute infectious chorea in children. Treatment with haloperidol remains effective in the symptomatic treatment of these choreas.
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- 2023
7. Mise en place d’une consultation de neurologie a l’hopital de Tivaouane, dans la region de thies au Senegal : Que retenir apres presque quatre ans d’activite ? Setting up a neurology consultation at the Tivaouane hospital, in the thies region of Senegal : What to retain after almost four years of activity ?
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Sarr, Mamadou Moustapha, Kane, Youssoupha Mbaye, Sarr, Thérèse Marianne, Ka, Mamadou, Marone, Zeïnabou, Diop, Alassane Mamadou, Gaye, Ndiaga Matar, Seck, Lala Bouna, Toure, Pape Souleymane, Touré, Kamadore, Ndiaye, Moustapha, and Diop, Amadou Gallo
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Neurology, Consultation, Tivaouane, Thiès, Reason ,Neurologie, Consultation, Tivaouane, Thiès, Motif - Abstract
IntroductionLa neurologie est la spécialité médicale qui étudie les maladies du système nerveux (central et périphérique). Au Sénégal, elle a été pendant longtemps cantonnée à Dakar. L’avènement de l’UFR Santé a favorisé la mise en place d’une consultation de neurologie à l’hôpital de Tivaouane depuis 2014. L’objectif de notre travail était de faire le bilan de cette activité après presque quatre ans.MéthodologieA partir du registre de consultation, nous avons collecté et analysé les données sociodémographiques et les motifs de consultation des patients entre Avril 2014 et Janvier 2018.Résultats1112 patients ont été consultés durant la période dont 59% de femmes. La tranche d’âge la plus représentative était 35-70 ans avec 47,9%. Les principaux motifs de consultation étaient représentés par les lombosciatalgies (25%), les crises comitiales (11,2%), les céphalées (9,3%), l’hémiplégie (5,5%), des paresthésies (5%), les lombalgies 2,5 %, le syndrome parkinsonien (1,8%), les cervicalgies (1,7%), les vertiges (1,3%).Discussion et conclusionNos résultats montrent donc qu’il y a une grande diversité des motifs de consultation neurologique à Tivaouane chez des patients qui, pour l’essentiel sont des adultes jeunes. Ils nous permettent aussi d’avoir, dans un premier temps, une vision panoramique des motifs de consultation et, dans un deuxième temps, d’envisager des études ciblées, notamment pour les motifs les plus fréquents comme les lombosciatalgies, les crises comitiales et les céphalées par exemple. Background and purposeNeurology is the medical specialty that studies diseases of the nervous system (central and peripheral). In Senegal, it was for a long time confined to Dakar. The advent of the UFR Santé has favored the establishment of a neurology consultation at the Tivaouane hospital since 2014. The objective of our work was to present the results of this activity after almost four years.MethodFrom the consultation register, we collected and analyzed the socio-demographic data and the reasons for consulting patients between April 2014 and January 2018. 1112 patients were consulted during the period, 59% of whom were women. The most representative age group was 35-70 years old with 47.9%. The main reasons for consultation were represented by lumbosciatalgia (25%), seizures (11.2%), headaches (9.3%), hemiplegia (5.5%), paresthesias (5%), low back pain 2.5%, parkinsonian syndrome (1.8%), neck pain (1.7%), dizziness (1.3%).Discussion and ConclusionOur results therefore show that there is a great diversity of reasons neurological consultation in Tivaouane for patients who, for the most part, are young adults. They also allow us to have, initially, a panoramic vision of the reasons for consultation and, secondly, to consider targeted studies, in particular for the most frequent reasons such as lumbosciatalgia, seizures and headaches for example.
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- 2023
8. Initial analysis of urban forestry in Mbour Municipality, Senegal
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Faye, Elhadji, Toure, Mamoudou Abdoul, Diallo, Hady, Ndiaye, Moustapha, and Faye, Papa Diène
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Diversification of urban flora is undertaken by several municipalities in different forms around the world. This global effort also concerns senegalese municipalities and must be assessed. The objective of the work is to evaluate urban forestry in the municipality of Mbour. To do this, a floristic inventory was carried out at the level of target quarters, wooded areas, roads and technical services and data were analyzed. Results showed that concessions and wooded areas are richer than technical services and main roads. Seventy-seven plant species from concessions and wooded areas representing 37 families were identified and listed particularly in the Mimosaceae family. Along the various roads in the urban transport network, 1075 trees representing 16 species and 11 families have been registered mainly among Meliaceae. Technical services included 42 species and 295 trees: 21 species and 53 individuals in forest service, 17 and 99 in rural development divisional service (SDDR), 12 and 42 for urban service, 11 and 71 for municipality, 5 and 30 in the prefecture. Trees are present in Mbour town. Regular monitoring will allow their spatio-temporal dynamics and make necessary improvements 
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- 2023
9. Automatic detection and counting of fisheries using fish images.
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Tall, Marc Momar, Ngom, Ibrahima, Sadio, Ousmane, Coulibaly, Adama, Diagne, Ibrahima, and Ndiaye, Moustapha
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CLASSIFICATION of fish ,ARTIFICIAL intelligence ,FISH population estimates ,BYCATCHES ,FISHERIES ,DATABASES - Abstract
In Senegal, stock recovery and fish classification are based on manual data collection, and the fish caught by the fishery are not often declared. What's more, data collection suffers from a lack of tools for monitoring and counting fish caught at fishing docks. Researchers have carried out studies on the fishery in Senegal, but data collection is almost non-existent. Moreover, there is no local fisheries database or automatic detection and counting algorithm. In this paper, a semantic segmentation algorithm is proposed using intelligent systems for the collection of fishery catches, for the formation of the local database. The data are collected by taking images of fish at the Soumbédioune fishing wharf in Senegal, and are completed with the Fishbase database. They were applied to the algorithm and resulted in a segmented dataset with masks. This constitutes our local database. The database is used with YOLO v8. The latter is very important for detecting images with bounding boxes in order to train the model. The results obtained are very promising for the proposed automatic poison detection and counting model. For example, the recall-confidence scores translate into bounding box performance with scores ranging from 0.01 to 0.75, confirming the performance of this model with bounding boxes. [ABSTRACT FROM AUTHOR]
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- 2023
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10. Epidemiology of childhood stroke in Senegal
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Mbaye , Khalifa Ababacar, Diagne , Rokhaya, Sow , Papa Souleye, Cisse , Ousmane, Gaye , Ndiaga Matar, Diop , Alassane Mamadou, Ka , Mamadou, Mbodji , Ahmadou Bamba, Mbacke , Serigne Saliou, Ndong , Marie Yandé Emilie, Diop-Sene, Marième Soda, Sow , Adjiaratou Dieynabou, Basse , Anna Mbodji, Ndiaye , Ousmane, Diop , Gallo Amadou, and Ndiaye , Moustapha
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Hemorrhagic stroke ,Ischemic stroke ,Children ,Senegal - Abstract
Introduction:Publications on childhood strokes are relatively rare in Africa while the main etiological factors reported in the literature are present on the continent. This study aimed at defining the risk factors, clinical and paraclinical aspects of stroke in children in Dakar (Senegal).Methods:It was a restrospective multicenter study in the pediatric departments of Dakar university hospitals (Fann, Diamniadio and Albert Royer) between January 2005 and January 2020 of children aged 2 months to 18 years.Results:We collected 240 cases of stroke including 201 cases of ischemia and 39 cases of hemorrhage. The mean age was 60 months. Clinical manifestations were predominantly hemiplegia (33.33%) and signs of raised intracranial pressure (20.51%) for hemorrhagic strokes. In ischemic stroke, hemiplegia (79.60%) and seizures (18.05%) were predominant. The middle cerebral artery was the most affected (63.68%) in ischemic strokes. Supratentorial hemorrhagic attacks represented 94.8% and infratentorial attacks 5.12%. The main factors were sickle cell disease and heart diseases for ischemic strokes; vascular malformations for hemorrhagic strokes.Conclusion:Child stroke remains common in children with modifiable risk factors. The frequency of sickle cell disease and vascular malformations testify the need for multidisciplinary collaboration for better care of children.
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- 2022
11. Surveillance of Viral Encephalitis in the Context of COVID-19: A One-Year Observational Study among Hospitalized Patients in Dakar, Senegal
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Kahwagi, Jamil, Seye, Al Ousseynou, Mbodji, Ahmadou, Diagne, Rokhaya, Mbengue, El Hadji, Fall, Maouly, Andriamandimby, Soa Fy, Easton, Ava, Faye, Martin, Fall, Gamou, Dia, Ndongo, Ndiaye, Babacar, Ndiaye, Momo Banda, Gueye, Alle, Mbacke, Serigne Saliou, Kane, Fatou, Ghouriechy, Mohamed Inejih El, Investigators, Ensene, Seck, Lala Bouna, Gaye, Ndiaga Matar, Sall, Amadou Alpha, Ndiaye, Moustapha, Faye, Ousmane, Diop, Amadou Gallo, Heraud, Jean‐michel, University Hospital of Fann [Dakar, Senegal], Institut Pasteur de Dakar, Réseau International des Instituts Pasteur (RIIP), Centre Hospitalier National de Pikine [Sénégal], Institut Pasteur de Madagascar, Encephalitis Society, University of Liverpool, and Jamil Kahwagi and Jean-Michel Heraud received financial support from the Encephalitis Society through the 2021 International Research Seed Funding.
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Adult ,viruses ,encephalitis ,virus ,MESH: Viruses ,MESH: Senegal ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Virology ,Humans ,MESH: COVID-19 ,MESH: SARS-CoV-2 ,Encephalitis, Viral ,Prospective Studies ,[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,MESH: Humans ,herpetic viruses ,SARS-CoV-2 ,Senegal ,Africa ,COVID-19 ,MESH: Adult ,[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology ,MESH: Prospective Studies ,MESH: Encephalitis, Viral ,Infectious Diseases ,Viruses ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,MESH: Encephalitis ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie - Abstract
International audience; The burden of encephalitis and its associated viral etiology is poorly described in Africa. Moreover, neurological manifestations of COVID-19 are increasingly reported in many countries, but less so in Africa. Our prospective study aimed to characterize the main viral etiologies of patients hospitalized for encephalitis in two hospitals in Dakar. From January to December 2021, all adult patients that met the inclusion criteria for clinical infectious encephalitis were enrolled. Cerebrospinal fluids, blood, and nasopharyngeal swabs were taken and tested for 27 viruses. During the study period, 122 patients were enrolled. Viral etiology was confirmed or probable in 27 patients (22.1%), with SARS-CoV-2 (n = 8), HSV-1 (n = 7), HHV-7 (n = 5), and EBV (n = 4) being the most detected viruses. Age groups 40–49 was more likely to be positive for at least one virus with an odds ratio of 7.7. The mortality was high among infected patients, with 11 (41%) deaths notified during hospitalization. Interestingly, SARS-CoV-2 was the most prevalent virus in hospitalized patients presenting with encephalitis. Our results reveal the crucial need to establish a country-wide surveillance of encephalitis in Senegal to estimate the burden of this disease in our population and implement strategies to improve care and reduce mortality.
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- 2022
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12. Weber's syndrome revealing a Percheron artery infarction: A case report.
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Mbodji, Ahmadou Bamba, Faye, Ibrahima, Diop, Ndeye Rokhaya, and Ndiaye, Moustapha
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SYMPTOMS ,ARTERIES ,COMPUTED tomography ,SYNDROMES ,INFARCTION ,ANGIOGRAPHY - Abstract
Key Clinical Message: Weber's syndrome revealing a Percheron artery infarction is a rare clinical occurrence. Its diagnosis requires careful clinical examination and brain MRI, which is the gold standard for diagnosis. If this is not available, combined cerebral CT scan with a CT angiography of supra‐aortic arteries may be useful for the diagnosis. Percheron's artery (PA) occlusion is an uncommon type of stroke involving paramedian thalamus and/or midbrain infarction. It accounts for 4%–18% of all thalamic infarcts and 0.1%–2% of all strokes. Its clinical manifestations are variable and its mode of presentation as Weber's syndrome is exceptional due to the unusual clinical presentation. [ABSTRACT FROM AUTHOR]
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- 2023
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13. Spectrum of movement disorders: Experience of a one and half year of existence of the first specialized center in Senegal
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Fall, Maouly, Dardare, Ibrahim M., Diop, Alassane M., Pelagie, Michel A., Kahwagi, Jamil, Dechacus, Ghislain C., Gaye, Ndiaga M., Rizig, Mie, Diagne, Ngor S., Ndiaye, Moustapha, and Diop, Amadou G.
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- 2022
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14. Le profil lipidique et glucidique des accidents vasculaires cérébraux ischémiques à Dakar
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Cisse Ousmane, Dadah Samy Mohamed Lemine, Ba Fatoumata, Ba El Hadji Makhtar, Diop Marieme Soda, Diagne Ngor Side, Adjaratou Dieynaba, Basse Anna Modji, Touré Kamadore, Ndiaye Moustapha, DiopAmadou Gallo, and Ndiaye Mouhamadou Mansour
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accident vasculaire cérébral ischémique ,glycémie ,bilan lipidique ,sénégal ,Medicine - Abstract
L'accident vasculaire cérébral (AVC) se définit comme le développement rapide de signes cliniques localisés ou globaux de dysfonction cérébrale sans autre cause apparente qu'une origine vasculaire. Différents facteurs de risque ont été identifiés et associés à la survenue des AVC ischémiques dont les perturbations du métabolisme glucidique et lipidique. Nous avons mené une étude rétrospective à la clinique neurologique de Fann. Notre étude a porté sur les dossiers des patients hospitalisés du 1er Janvier au 31 Décembre 2010 pour un AVCI confirmé par l'imagérie. Tous nos patients avaient bénéficié d'un bilan lipidique complet (cholestérol total, triglycérides, HDL ; le taux de LDL ayant été calculé grâce à la formule de Friedwald, dun bilan rénal et d'une glycémie à jeun prélevés dans les 48 heures suivant l'admission. Les données ont été analysées en mesure univariée, ensuite bivariée grâce au logiciel SPSS 16.0. Nous avons colligé 235 dossiers. Les patients étaient âgés de 10 à 99 ans avec une moyenne à 67,06 ans. Le sexe masculin était à 42,55% , le sex-ratio était de 0,74 en faveur des femmes. Vingt Six pour cent avaient une glycémie à jeun anormale à la phase aiguë de l'AVCI. Le bilan lipidique montrait une augmentation du cholestérol total chez 52,34% des patients. Le HDL était bas chez 34,47% des patients . L'hypertriglycéridémie n'avait été observée que chez 3% des patients. Le LDL était élevé chez 12,76% . L'indice d'athérogénicité était élevé chez 25,53% des patients. Des perturbations de la glycémie et du bilan lipidique sont très souvent associées à l'AVCI et doivent être prises en compte pour assurer une meilleure prévention secondaire.
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- 2016
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15. Polymyositis anti-SRP antibodies and pregnancy about 2 cases
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Cissé Ousmane, Ba El Hadji Makhtar, Ba Fatoumata, Gams Daniel Massi, Daddah Sami Mouhamed Lémine, Diop-Séne Marieme Soda, Sow Adjaratou Dieynaba, Basse Anna, Seck Lala Bouna, Ndiaye Moustapha, Diop Amadou Gallo, and Ndiaye Mouhamadou Mansour
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myopathy ,anti-srp antibodies ,pregnancy ,post-partum ,corticosteroid ,Medicine - Abstract
Anti-SRP myopathy represents 4 to 6% of all the inflammatory myopathies. It has been described since the 80s and its influence on pregnancy and vice versa has been highlighted recently. We report two cases of anti-SRP myopathy associated with pregnancy. In the first case, the initial manifestations of the disease started in post partum and the second case was an anti-SRP myopathy patient before pregnancy. In both cases we objectified outbreaks during post-partum. Pregnancy seems to promote outbreaks. The inactive myopathy seems to presents no serious maternal-fetal complications as well as the usual dose of corticosteroids. The treatment (corticosteroid) during pregnancy is indicated given the risk of worsening during the post-partum.
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- 2016
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16. NEUROCOVID: Experience of a Sub-Saharan African country, example of Senegal
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Kahwagi, Jamil, Mbodj, Ahmadou, Diagne, Rokhaya, Toure, Kamadore, Ndiaye, Moustapha, and Diop, Amadou
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- 2021
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17. Hospital direct cost of stroke in sub Saharan Africa: The case of Senegal
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Nyassinde, Japhari, Toure, Kamadore, Massi, Daniel Gams, Ndiaye, Moustapha, Abass, Cissé, Camara, Ibrahima, and Diop, Amadou
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- 2021
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18. Assessment of the potential of Vachellia seyal and Prosopis chilensis for the reclamation of saline soil lands in the peanut basin production of Senegal.
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Thiao, Mansour, Sene, Godar, Ndiaye, Moustapha, and Samba Ndao Sylla, El Hadji
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Soil properties and microbial activities are indicators that shape plant communities and evolution. We aimed to determine the interdependency between trees, belowground herbaceous plants, soil characteristics, and arbuscular mycorrhizal communities. Vachellia seyal and Prosopis chilensis and their associated herb layers were targeted. Soils sampled beneath the trees and outside the canopies were subjected to physicochemical and microbial characterization. Randomly collected living roots of trees and dominant herbs were checked for arbuscular mycorrhizal colonization. A tree seedlings nursery was conducted using black bags filled with the following substrates: natural soil 100%, soil mixed with leaf tree plants (LTPs) as organic matter at 10%, soil mixed with LTP at 20%, soil mixed with LTP at 30%, and soil mixed with LTP at 50%. As a result, the presence of trees improves both herb richness and diversity. Soil mycorrhizal inoculum potentials are higher beneath V. seyal than P. chilensis and decreased significantly with increasing distance from trees. The soil MIP decreased with increasing organic matter content for both tree species but was more pronounced for P. chilensis. Soil salinity is lower beneath V. seyal and higher under P. chilensis and outside the canopies. Soil fertility parameters such as carbon, nitrogen, and available phosphorus are higher beneath the trees and then decreased as the distance to the trees increases. We conclude that microbial communities, soil properties, and herb richness and diversity increased beneath the trees but decreased with increasing distance from the trees. This effect is tree species-dependent as P. chilensis increased soil salinity and decreased the belowground density of herbs. [ABSTRACT FROM AUTHOR]
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- 2022
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19. N°376 – Continuous spike and waves during slow sleep in the neurological department of Fann National University hospital of Dakar: Topographic aspects and age
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Seck, Lala Bouna, Sarr, Mamadou Moustapha, Akrim, Hanane, Ka, Mamadou, Diop, Alassane Mamadou, Diop Sene, Marième Soda, Gaye, Arame, Basse Faye, Anna Modji, Sow, Adjaratou Djeynabou, Ndiaye, Moustapha, and Diop, Amadou Gallo
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- 2023
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20. Epilepsie-absences de l’enfant et de l’adolescent au Senegal aspects epidemiologiques, diagnostiques, therapeutiques et pronostiques
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Fall, Maouly, Afagnon, Dossou Parfait, Sow, Adjaratou Dieynabou, Seck, Lala Bouna, Touré, Kamadore, Ndiaye, Moustapha, and Ndiaye, Mouhamadou Mansour
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adolescent, enfant, épilepsie-absence, prise en charge, Sénégal, care, children, absence epilepsy, Senegal, teenager - Abstract
Description: L’épilepsie-absence est un syndrome épileptique généralisé, fréquent, de cause présumée génétique, caractérisé par la survenue d’épisodes fréquents de rupture brutale et complète du contact sans perte de tonus.Objectif: L’objectif était de décrire l’épidémiologie et les caractéristiques cliniques de l’épilepsie-absence chez l’enfant et l’adolescent.Méthode: Nous avons mené une étude transversale longitudinale, portant sur 53 patients, de décembre 2003 à mars 2014 en colligeant les données épidémiologiques, diagnostiques, thérapeutiques et évolutives. L’analyse des données s’est faite avec le logiciel statistique CSPro 5.0 avec calcul de fréquences et moyennes.Résultats: Cinquante trois patients dont 42 enfants et 11 adolescents ont été colligé avec un âge moyen de 10 ans. L’âge moyen de début des crises était de 6,8 ans chez les enfants et 12,4 ans chez les adolescents. On notait une prédominance féminine à 52,4 % chez les enfants et masculine à 63,6 % chez les adolescents. Une consanguinité parentale était retrouvée dans 55,5 % chez l’enfant et 37,5 % chez l’adolescent. Quarante pourcent des enfants présentaient des antécédents familiaux d’épilepsie. Les crises survenaient spontanément dans 86,8 % des cas avec une durée moyenne de 10 secondes environ. Le Valproate de sodium a été utilisé chez tous nos patients avec une maitrise dans 81,6 % à trois mois. L’évolution de l’épilepsie-absence était globalement satisfaisante avec des difficultés d’apprentissage observées chez 22,6 % des patients.Conclusion: L’épilepsie-absence est fréquente, de causes multifactorielles et peut retentir sur le devenir psychosocial.Mots clés: adolescent, enfant, épilepsie-absence, prise en charge, SénégalEnglish Title: Absences epilepsy of children and teenager in Senegal epidemiological, diagnostic, therapeutic and prognostic aspectsEnglish AbstractBackground: Absence-epilepsy is a generalized epileptic syndrome, frequent, of presumed genetic cause, characterized by the occurrence of frequent episodes of sudden, profound impairment of consciousness without loss of body tone.Objective: The objective was to describe the epidemiology and clinical features of absence-epilepsy in children and adolescents.Methods: We conducted a longitudinal cross-sectional study of 53 patients from December 2003 to March 2014, collecting epidemiological, diagnostic, therapeutic and evolutionary data. Analysis of data was done with CSPro 5.0 statistical software with frequency and averaging calculations.Results: Fifty-three patients including 42 children and 11 adolescents were enrolled with an average age of 10 years. The mean age of onset of seizures was 6.8 years in children and 12.4 years in adolescents. We found female prevalence of 52.4% in children and male prevalence of 63.6% in teenagers. Parental consanguinity was found in 55.5% in children and 37.5% in adolescents. Forty percent of children had a family history of epilepsy. Seizures occurred spontaneously in 86.8% of cases with an average duration of about 10 seconds. Sodium valproate was used in all our patients with a mastery in 81.6% at three months. The evolution of absence-epilepsy was generally satisfactory but learning difficulties were observed in 22.6% of patients.Conclusion: Absence-epilepsy is common, have multifactorial causes and can affect the cognitive outcome.Keywords: care, children, absence epilepsy, Senegal, teenager
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- 2019
21. Thrombose veineuse cerebrale au CHU de Fann, Dakar : a propos de 30 cas
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Diouf Mbourou, Nelly, Gay, Matar Ndiaga, Nsounda, Annick, Sounga Banzouzi, Prince Eg, and Ndiaye, Moustapha
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Dakar, Fann, Thrombose veineuse cérébrale - Abstract
Introduction: La thrombose veineuse cérébrale représente une pathologie vasculaire veineuse autrefois dite rare.Objectif: L’objectif principal de notre étude était d’étudier les différents aspects cliniques, paracliniques, étiologiques et évolutifs des thromboses veineuses cérébrales.Méthodologie: Il s’agissait d’une étude prospective de 30 cas de thromboses veineuses cérébrales admis au service de neurologie de Fann durant la période allant de janvier 2013 à juillet 2016. L’imagerie cérébrale était le critère indispensable pour confirmer le diagnostic.Résultats: Notre enquête comportait 21 femmes et 9 hommes avec un âge moyen de 34,4 ans. L’installation des signes était subaigüe dans la majorité des cas. Le motif d’admission était polymorphe, dominé par les céphalées (86,7%), les vomissements (60,0%), l’hémiplégie (56,7%). L’imagerie cérébrale révélait majoritairement 14 cas de thrombose du sinus latéral (46,7 %) et 10 cas de sinus longitudinal supérieur (33,3%). Les causes non infectieuses (50%) notamment gynéco-obstétricales dominaient. L’évolution sous héparinothérapie était le plus souvent favorable ; seules des céphalées séquellaires demeuraient.Conclusion: La thrombophlébite cérébrale constitue une urgence pronostique et thérapeutique. La variabilité du diagnostic pourrait expliquer le retard de la prise en charge.Mots-clés: Dakar, Fann, Thrombose veineuse cérébraleEnglish Title: Cerebral venous thrombosis at University Hospital of Fann, Dakar: about 30 casesEnglish AbstractIntroduction: Cerebral venous thrombosis brings forth a vascular vein thrombosis previously said to be rare.Objective: Our main objective was to investigate different clinical, paraclinical, etiological and evolutive aspects of cerebral venous thrombosis.Méthodology: This prospective study involved thirty (30) cases of cerebral venous thrombosis admitted at the Fann’s neurology service from January 2013 to July 2016. Brain CT-scan or MRI were used to confirm the diagnostic.Results: Our investigation comprised 21 women and 9 men with mean age 34.4 years. The onset was sub-acute in the majority of cases. Symptoms and signs on admission were predominantly cephalalgia (86.7%), vomitting (60.0%), hemiplegia (56.7%). Brain imaging revealed a majority of 14 cases of thrombosis of the lateral sinus (46.7%), and 10 cases of superior longitudinal sinus (33.3%). Non infectious causes (50%) of gyneco-obstetric origin dominated. Improvement under heparin therapy was most often favorable; only cephalalgia however persisted. Conclusion: Cerebral veinous thrombosis presents a prognostic and therapeutic emergency. The variability of the diagnostics could explain the delay on care.Keywords: Cerebral venous thrombosis, Dakar, Fann, Cerebral venous thrombosis, Dakar, Fann
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- 2019
22. Environmental and occupational risk factors of amyotrophic lateral sclerosis in Senegal
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Gams, Massi Daniel, Touré, Kamadore, Sow, Adjaratou Dieynabou, Nyassinde, Japhari, Mapoure, Njankouo Yacouba 4, Ndiaye, Moustapha, and Diop, Amadou Gallo
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Africa, ALS, Dakar, pesticides, risk factors - Abstract
Background: The pathophysiology of Amyotrophic lateral sclerosis (ALS) is not well known, but seems to be multifactorial. Genetic and environmental factors increase the risk of developing ALS.Methods: We conducted case-control study from July 2015 to June 2017, comparing exposure to risk factors in 23 ALS cases and 53 controls in the department of neurology of Fann national teaching hospital in Senegal. Results: The mean ages of cases and controls were 44.3 ± 16.3 years and 48.3 ± 17 years respectively. There was a male predominance. In the bivariate analysis, factors significantly associated to ALS were: living outside Dakar (OR: 26.6; 95% CI [5.5-127.7]), farmer profession (OR: 13.3; 95% CI [2.6-69.9]), exposure to pesticides (OR: 15.3; 95% CI [3.7-63.4]), and chemical fertilizers (OR: 5.2; 95% CI [1.7-15.4]). In multivariate analysis, living outside Dakar (OR: 16.4; 95% CI [3.2-82.8]) and exposure to pesticides (OR: 6.0; [1.3-29.1]) were identified as the main risk factors of ALS in this study. Conclusion: We found relatively young ALS patients. This study identified significant role of living outside Dakar and exposure to pesticides. A multi-center study with a larger number of ALS patients would certainly be more accurate in determining more risk factors and their causality in ALS among African population.French title: Facteurs de risque environnementaux et professionnels de la sclerose laterale amyotrophique au Senegal
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- 2019
23. Facial spasms revealing a Parry-Romberg syndrome: A case report
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Mbodji, Ahmadou Bamba, Seck, Momar, Diagne, Ngor Side, Faye, Ibrahima, Mbacke, Serigne Saliou, and Ndiaye, Moustapha
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- 2022
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24. Metastatic Spinal Cord Compression Secondary to Liver Cancer
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Gams Massi, Daniel, Nyassinde, Japhari, Diagne, Ngor Side, Abdennaji, Ramy, Toure, Kamadore, Ndiaye, Moustapha, Diop, Amadou Gallo, and Ndiaye, Mouhamadou Mansour
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Article Subject - Abstract
Metastatic spinal cord compression (MSCC) is a medical emergency that requires rapid diagnosis and treatment to reduce pain, to preserve neurological functioning, and to prolong survival. The diagnosis of liver cancer is often neglected in the differential diagnosis of MSCC. Treatment is usually palliative and evolution is often fatal. This is a case report of a 28-year-old patient living in Mauritania hospitalized in November 2014 at the neurology department of Fann national teaching hospital in Dakar, for the management of a chronic dorsal spinal cord compression. The radiological and laboratory investigations done revealed the metastatic compression originating from a liver cancer with elevated alpha-fetoprotein and aspartate transaminase, positive hepatitis B surface antigen, and multiple metastasis in the lungs, mediastinum, ribs, iliac, and peritoneum. The hip joint X-ray showed a spontaneous fracture of the right femoral neck. The multidisciplinary treatment was palliative and the evolution was fatal within the month of hospitalization. Earlier diagnosis and treatment of MSCC may not have saved the life of the patient but may have prevented much suffering and would likely have prolonged the life of a young man.
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- 2017
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25. Maladie de Krabbe : a propos d’un cas
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Ndiaye, Moustapha, Cisse, Abass Fodé, Basse, Anna Modji, Sow, Adjaratou Dièynaba, Diop, Marème Soda, Seck, Lala Bouna 1, Toure, Kamadore, Diop, Amadou Gallo, and Ndiaye, Mouhamadou Mansour
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Acquisitions psychomotrices, galactocérébrosidase - Abstract
Introduction Le diagnostic d’une maladie lysosomiale est utile surtout dans les familles à risque en vue d’effectuer un conseil génétique. Nous rapportons l’observation d’un enfant vu pour la première fois à 13 mois, pour une perte progressive des acquisitions psychomotrices. Dans ses antécédents on notait une consanguinité parentale de premier degré. L’imagerie par résonance magnétique cérébrale révélait des hypersignaux diffus bilatéraux et symétriques periventriculaires, des noyaux lenticulaires et des noyaux dentelés du cervelet sur les séquences T2 et Flair associés à des hyposignaux T2 des thalamus. Le dosage de la Bêta galatocérébrosidase chez l’enfant et les deux parents a permis de faire le diagnostic de maladie deKrabbe.Conclusion Une maladie métabolique doit être recherchée de parti pris chez tout enfant présentant une régression progressive des acquisitions psycho-motrices mais l’insuffisance du plateau technique en Afrique limite considérablement les possibilités diagnostiques.
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- 2016
26. Qualite de vie apres un accident vasculaire cerebral au Senegal: a propos de 50 cas
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Dadah, Samy Mohamed Lemine, Basse, Anna Modji, Sene, Marième Soda, Ba El, Hadji Makhtar, Seck, Lala Bouna, Sy, Abdoul Bocar, Diagne, Side Ngor, Ndiaye, Moustapha, Touré, Kamadore, Sow, Adjaratou Dièynaba, Diop, Amadou Gallo, and Ndiaye, Mouhamadou Mansour
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AVC, qualité de vie, Sénégal, quality of life, stroke, Senegal - Abstract
Introduction: L’accident vasculaire cérébral (AVC) constitue une cause majeure de mortalité et de handicap chez les survivants. La qualité de vie dépend de la nature du handicap et de sa perception par le patient, son entourage et la communauté.Objectif: Notre objectif était d’évaluer le handicap après un AVC et d’apprécier son retentissement sur la qualité de vie des patients victimes.Patients et Méthodes: Nous avons mené une étude prospective, longitudinale de février 2008 à mai 2009, à la clinique neurologique de FANN. Les patients étaient vus à la phase initiale de l’AVC et 6 mois après et soumis à un questionnaire comportant plusieurs items relatifs à la nature de l’accident vasculaire cérébral, le vécu psychoaffectif et socioprofessionnel, l’index de Barthel a été utilisé chez tous les malades.Résultats: Nous avons colligé 50 patients âgés de 15 à 82 ans, avec une sex-ratio de 1,27. L’accident était ischémique dans 70%, hémorragique dans 30% des cas. 66% des patients avaient un index de Barthel entre (60-100), 6% étaient entre (0-20). Le score était meilleur chez les jeunes (15ans-34ans) qui avait tous un index entre (60-100). Par ailleurs 50% des patients de la tranche supérieure à 75ans étaient dans l’intervalle (60-100). Les AVCH avaient des Meilleurs résultats avec 73,3% à un index entre (60-100). seul 12% ont été réinsérés, sur le plan professionnel. 54,05%, n’ont pas noté de changement dans leur vie conjugale. Sur le plan familial, 56% ne notaient aucun changement. Une grande partie de notre série 44% acceptaient bien leurs déficits,. 70% ne faisaient plus d’activités de temps libre.Conclusion: La qualité de vie est un concept multidimensionnel qui incorpore outre la santé physique les aspects mentaux et sociaux de la maladie.Mots clés: AVC, qualité de vie, SénégalEnglish Title: Quality of life after stroke in Senegal: about 50 casesEnglish AbstractIntroduction: Stroke is a major cause of mortality and disability in survivors. The quality of life depends on the nature of disability and its perception by the patient, his or her environment and community. The aim of this study was to assess disability after stroke and its impact on quality of life of patients (victims).Patients And Methods: We conducted a prospective, longitudinal study from February 2008 to May 2009, at the Neurological Clinic of Fann. Patients were seen at the initial phase of stroke and 6 months later and answered a questionnary containing 13 items like nature of stroke disability psychological emotional and socioprofessional filds. The index of barthel was used at all the patient’s.Results: We collected, were like this 50 patients aged 15-82 years with a sex ratio of 1.27. The accident was ischemic in 70% of cases, hemorrhagic in 30% of cases. 66% had a Barthel index between (60-100), 6% were between (0-20). The score was significantly better in young series (15-34), which all have a Barthel index between (60-100), more over 50% of patients in the portion above 75 years were in the range (60 - 100). Hemorragic stroke had the best results with 73.3% a Barthel index between (60-100). On a professional level, only 12% patients were rehabilitated. 54.05% didn’t notice any change in their marital life. On the home front, 56% noted any change. A large part of our series 44% accepted although their deficits. 70% didn’t have any more free time activities.Keywords: quality of life, stroke, Senegal
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- 2016
27. Selective attention of students suffering from primary headaches in a pain free period: a case control study
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Fogang, Fogoum Yannick, Touré, Kamadore, Naeije, Gilles, Ndiaye, Moustapha, Diop, Amadou Gallo, and Ndiaye, Mouhamadou Mansour
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Selective attention, mental flexibility, neuropsychology, headache, migraine - Abstract
Background: Headache patients frequently complain about difficulties in attention and concentration, even when they are headache-free and psychometric studies concerning attentional deficits in headache patients between attacks are scarce.Objective: To evaluate selective attention of headache patients in a pain free period and compare them with healthy volunteers.Subjects and Methods: We performed, between February 2011 and July 2011, a case-control study, including 45 university students consulting for primary headaches, matched with 45 healthy students as controls. Headaches were classified according to the International Headache Society criteria (IHS, 2004). Subjects with a history of brain injury, epilepsy and visual disturbancies were excluded. Mood disorders were assessed using the Hospital Anxiety Depression (HAD) questionnaire. Selective attention was evaluated using the D-KEFS color-word interference test.Results: Mean age of patients was 23.29 ± 2.55 years, versus 22.89 ± 2.04 years for controls (p = 0.2). Migraine and tension-type headaches were the only diagnosed headache types, respectively 55.56% and 44.44%. The selective attention score was -4.04 ± 7.08 for patients, versus -1.31 ± 7.73 for controls (p = 0.02). The mean mental flexibility score was lower in headache sufferers compared to controls (36.67 ± 6.79 versus 41.33 ± 6.23, p = 0.001). Gender, anxiety and depression scores, and temporal features of headache had no correlation with selective attention score.Conclusion: Selective attention and mental flexibility capacities seem to be reduced in primary headache sufferers in pain free period. These findings could contribute to our understanding of the pathophysiology of primary headaches.Keywords: Selective attention, mental flexibility, neuropsychology, headache, migraine
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- 2016
28. Infirmite motrice d’origine cerebrale : une serie Senegalaise
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Ndiaye, Moustapha, Tall, Isseu, Basse, Anna Modji, Touré, Kamadore, Seck, Lala Bouna, Sene, Marième Soda, Sow, Adjaratou Dièynaba, Diagne, Side Ngor, Diop, Amadou Gallo, Sow, Hussein Dembel, and Ndiaye, Mouhamadou Mansour
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Infirmité motrice cérébrale, Sénégal - Abstract
Introduction L’infirmité motrice cérébrale est le deuxième motif de consultation en neurologie pédiatrique après l’épilepsie. L’objectif de ce travail était de déterminer les facteurs étiologiques, de définir le profil clinique et évolutif de cette affection dans une population d’enfants au Sénégal.Methodologie Il s’agit d’une étude rétrospective, descriptive de dossiers de patients suivis en consultation de Neurologie pédiatrique à l’hôpital d’Enfants Albert Royer et au service de Neurologie du CHU Fann, entre Juillet 2003 et Févier 2009.Resultats Le travail a concerné 793 nourrissons dont l’âge moyen était de 2 ans. La prédominance était masculine (59%) et les facteurs étiologiques étaient dominés par les anomalies de la grossesse et de l’accouchement (50,9%), les malformations cérébrales et les infections du système nerveux central post-natales (6,2%). Les principaux signes cliniques étaient des troubles posturo moteurs dominés par l’hypotonie axiale, l’hémiplégie et la paraplégie spastiques, un contact social pauvre (23%), une épilepsie (35,6%). Les autres signes étaient des troubles neurosensoriels, du langage et du comportement. Les anomalies éléctroencéphalographiques étaient retrouvées chez 45,64% des enfants et les principales anomalies neuroradiologiques étaient l’atrophie corticale et/ou sous corticale, les lésions ischémiques et les malformations cérébrales. Le suivi de ces enfants a révélé que plus de 85% des patients sont perdus de vue du fait des coûts directs et indirects induits par la rééducation. Seuls 112 enfants ont été régulièrement suivis avec une médiane de 31,61 mois.Conclusion L’infirmité motrice cérébrale reste un problème de santé publique et appelle à des mesures préventives pour améliorer la santé reproductive.
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- 2016
29. Facteurs pejoratifs de l’epilepsie absence de l’enfant au Centre Hospitalier Universitaire De Fann de Dakar, Senegal
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Seck, Lala Bouna, Ould El Hacen, Cheikh, Ndiaye, Moustapha, Gueye, Lamine, Diop, Amadou Gallo, and Ndiaye, Mouhamadou Mansour
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absence, Dakar, enfant, épilepsie, pronostic, Sénégal, absence, childhood, Dakar, epilepsy, prognosis, Senegal - Abstract
Objectif: Identifier les facteurs de mauvais pronostic dans une série de patients souffrant d’une épilepsie absence de l’enfant.Méthode: Nous avons colligé des dossiers de patients suivis pour épilepsie absence de l’enfant au service de neurologie du Centre Hospitalier Universitaire Fann de Dakar, en relevant les données de l’état civil et les caractéristiques du tableau clinique.Résultats: Vingt-huit enfants ont présenté une épilepsie absence de l’enfant, avec 53.6% de filles et 46.4% de garçons. L’âge de début variait entre 4 et 12 ans avec une répartition superposable entre les 2 sexes. 61.5% des garçons et 13.33% des filles avaient des crises généralisées tonico-cloniques associées. L’évolution des crises était favorable chez tous, sous Valproate de sodium dans 89.2% des cas. L’échec scolaire, retrouvé chez 53.6% des enfants, était plus fréquent : chez les garçons, en cas de crises généralisées tonicocloniques associées et dans les cas où l’installation de l’épilepsie absence était plus tardive.Conclusion: L’épilepsie absence de l’enfant comporte des facteurs péjoratifs (sexe masculin, crises généralisées tonicocloniques associées, installation tardive) qui peuvent retentir sur le devenir psychosocial et assombrir le pronostic malgré une bonne maitrise des crises.Mots-clés: absence, Dakar, enfant, épilepsie, pronostic, SénégalEnglish Title: Pejorative factors of childhood absence epilepsy in Fann Teaching Hospital, Dakar (Senegal)English AbstractAim: To identify poor prognosis factors of childhood absence epilepsy.Methods: We collected data about children with childhood absence epilepsy in the Department of Neurology, Fann Teaching Hospital. The socio-demographic data and the clinical features of the epilepsy were noted.Results: Twenty-eight children suffered from childhood absence epilepsy, 53.6% of whom were girls and 46.4% boys. The age of onset varied from 4 to 12 years and was similar in both sexes. Associated generalized tonic-clonic seizures were present in 61.5% of boys and 13.33% of girls and occurred more frequently with delayed onset of the disease. All cases had a favorable outcome mainly with valproic acid treatment. Poor performance at school was observed in 53.6%, especially amongst the boys, those with associated generalized tonic-clonic seizures and those with delayed onset absence epilepsy.Conclusion: Although childhood absence epilepsy is considered benign, there are some factors that can affect the child’s psychosocial development and adversely affect the prognosis.Keywords: absence, childhood, Dakar, epilepsy, prognosis, Senegal
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- 2016
30. Le profil lipidique et glucidique des accidents vasculaires cérébraux ischémiques à Dakar
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Ndiaye Mouhamadou Mansour, Sow Adjaratou Dieynaba, Dadah Samy Mohamed Lemine, Ndiaye Moustapha, Diagne Ngor Side, Diop Amadou Gallo, Ba Fatoumata, Touré Kamadore, Basse Anna Modji, Diop Marieme Soda, Cisse Ousmane, and Ba El Hadji Makhtar
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medicine.medical_specialty ,Renal function ,bilan lipidique ,chemistry.chemical_compound ,Internal medicine ,Medicine ,Ischemic Cerebrovascular Accident ,Stroke ,lcsh:R5-920 ,medicine.diagnostic_test ,Cholesterol ,business.industry ,lcsh:Public aspects of medicine ,Hypertriglyceridemia ,Retrospective cohort study ,sénégal ,lcsh:RA1-1270 ,General Medicine ,medicine.disease ,Impaired fasting glucose ,chemistry ,accident vasculaire cérébral ischémique ,business ,Lipid profile ,glycémie ,lcsh:Medicine (General) - Abstract
L’accident vasculaire cérébral (AVC) se définit comme le développement rapide de signes cliniques localisés ou globaux de dysfonction cérébrale sans autre cause apparente qu’une origine vasculaire. Différents facteurs de risque ont été identifiés et associés à la survenue des AVC ischémiques dont les perturbations du métabolisme glucidique et lipidique. Nous avons mené une étude rétrospective à la clinique neurologique de Fann. Notre étude a porté sur les dossiers des patients hospitalisés du 1er Janvier au 31 Décembre 2010 pour un AVCI confirmé par l’imagérie. Tous nos patients avaient beneficié d’un bilan lipidique complet (cholestérol total, triglycérides, HDL ; le taux de LDL ayant été calculé grâce à la formule de Friedwald, d’un bilan rénal et d’une glycémie à jeun prélevés dans les 48 heures suivant l’admission. Les données ont été analysées en mesure univariée, ensuite bivariée grace au logiciel SPSS 16.0. Nous avons colligé 235 dossiers. Les patients étaient âgés de 10 à 99 ans avec une moyenne à 67,06 ans. Le sexe masculin était à 42,55% , le sex-ratio était de 0,74 en faveur des femmes. Vingt Six pour cent avaient une glycémie à jeun anormale à la phase aiguë de l’AVCI. Le bilan lipidique montrait une augmentation du cholestérol total chez 52,34% des patients. Le HDL était bas chez 34,47% des patients . L’hypertriglycéridémie n’avait été observée que chez 3% des patients. Le LDL était élevé chez 12,76% . L’indice d’athérogénicité était élevé chez 25,53% des patients. Des perturbations de la glycémie et du bilan lipidique sont très souvent associées à l’AVCI et doivent être prises en compte pour assurer une meilleure prévention secondaire.The Pan African Medical Journal 2016;25
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- 2016
31. Polymyositis anti-SRP antibodies and pregnancy about 2 cases
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Seck Lala Bouna, Ndiaye Mouhamadou Mansour, Daddah Sami Mouhamed Lémine, Ba Fatoumata, Ba El Hadji Makhtar, Gams Daniel Massi, Cisse Ousmane, Ndiaye Moustapha, Basse Anna, Sow Adjaratou Dieynaba, Diop-Sène Marieme Soda, and Diop Amadou Gallo
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Adult ,Pathology ,medicine.medical_specialty ,Pediatrics ,corticosteroid ,medicine.drug_class ,Myopathy ,030231 tropical medicine ,Case Report ,Disease ,Polymyositis ,environment and public health ,Antibodies ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,medicine ,Humans ,030212 general & internal medicine ,anti-SRP antibodies ,lcsh:R5-920 ,biology ,business.industry ,lcsh:Public aspects of medicine ,Postpartum Period ,Outbreak ,lcsh:RA1-1270 ,post-partum ,General Medicine ,medicine.disease ,Pregnancy Complications ,biology.protein ,Corticosteroid ,Female ,medicine.symptom ,Antibody ,business ,lcsh:Medicine (General) ,Signal Recognition Particle ,Postpartum period - Abstract
Anti-SRP myopathy represents 4 to 6% of all the inflammatory myopathies. It has been described since the 80s and its influence on pregnancy and vice versa has been highlighted recently. We report two cases of anti-SRP myopathy associated with pregnancy. In the first case, the initial manifestations of the disease started in post partum and the second case was an anti-SRP myopathy patient before pregnancy. In both cases we objectified outbreaks during post-partum. Pregnancy seems to promote outbreaks. The inactive myopathy seems to presents no serious maternal-fetal complications as well as the usual dose of corticosteroids. The treatment (corticosteroid) during pregnancy is indicated given the risk of worsening during the post-partum.The Pan African Medical Journal 2016;24
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- 2016
32. Gingival metastasis of a breast carcinoma.
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Ndiaye, Moustapha, Faye, Ababacar Diegane, Diouf, Mame Sanou, Ndiaye, Ciré, Sy, Abdou, Diallo, Adja Coumba, Loum, Birame, Deguenonvo, Richard, Diom, Evelyne Siga, Ndiaye, Malick, Ndiaye, Issa Cheikh, Diallo, Bay Karim, Tall, Abdourahmane, and Diouf, Raymond
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METASTATIC breast cancer , *NEOADJUVANT chemotherapy , *CARCINOMA , *BREAST tumors , *EMERGENCY medicine , *AXILLARY lymph node dissection , *GINGIVAL hyperplasia , *GINGIVAL grafts - Abstract
We report a case of metastasis to the gingiva of breast carcinoma. The breast tumor was treated with neoadjuvant chemotherapy followed by a radical mastectomy associated with axillary dissection. The gingival lesion occurred 7 months after surgery; the metastasis was confirmed by a biopsy. [ABSTRACT FROM AUTHOR]
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- 2020
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33. Parkinson’s disease in Senegal: epidemiologic, clinical and therapeutic aspects
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Gaye, Ndiaga Matar, Seck, Lala Bouna, Diagne, Ngor Side, Sow, Adjaratou Dieynabou, Diop, Alassane Mamadou, Cisse, Ousmane, Faye, Anna Basse, Diop, Marième Soda, Toure, Kamadore, Ndiaye, Moustapha, Diop, Amadou Gallo, and Ndiaye, Mouhamadou Mansour
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- 2016
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34. Neuromeningeal cryptococcosis in sub-Saharan Africa: Killer disease with sparse data.
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Assogba, Komi, Belo, Mofou, Wateba, Majeste Ihou, Gnonlonfoun, Dieu Donné, Ossou‑Nguiet, Paul M., Tsanga, Berenger B. C., Ndiaye, Moustapha, and Grunitzky, Eric K.
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CRYPTOCOCCOSIS ,AIDS ,HIV infections ,EPIDEMIOLOGY ,AGGLUTINATION tests ,FLUCONAZOLE - Abstract
Introduction: The extent of neuromeningeal cryptococcosis (NMC) has increased since the advent of HIV/AIDS. It has non-specific clinical signs but marked by high mortality. Objective: To analyze the characteristics of the NMC in sub-Saharan Africa. Materials and Methods: We have conducted a literature reviewed on the NMC in sub-Saharan Africa from the publications available on the basis of national and international data with keywords such as "Cryptococcus, Epidemiology, Symptoms, Outcomes and Mortality" and their equivalent in French in July 2011. All publications from 1990 to 2010 with 202 references were analyzed. The following results are the means of different studied variables. Results: We selected in final 43 publications dealing with the NMC which 24 involved 17 countries in Africa. The average age was 36 years old. The average prevalence was 3.41% and the average incidence was 10.48% (range 6.90% to 12%). The most common signs were fever (75%), headaches (62.50%) and impaired consciousness. Meningeal signs were present in 49% of cases. The mean CD4 count was 44.8cells/mm3. The India ink and latex agglutination tests were the most sensitive. The average time before the consultation and the hospital stay was almost identical to 27.71 days. The average death rate was 45.90%. Fluconazole has been the most commonly used molecule. Conclusion: The epidemiological indicators of NMC varied more depending on the region of sub-Saharan Africa. Early and effective taking care of patients to reduce diagnostic delay and heavy mortality remains the challenges. [ABSTRACT FROM AUTHOR]
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- 2015
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35. Epidemiological and clinical study of juvenile myasthenia gravis in Dakar, Senegal.
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Diop-Sene, Marieme Soda, Ndiaye, Moustapha, Cisse, Ousmane, Diop, Amadou Gallo, and Ndiaye, Mouhamadou mansour
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- 2017
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36. Electroencephalography in elderly in Neurophysiological Department of Fann University Hospital in Dakar.
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Seck, Lala Bouna, Sarr, Mamadou Moustapha, Diop, Alassane Mamadou, Diop-Sene, Marème Soda, Gaye, Arame, Faye, Anna Modji Basse, Sow, Adjaratou Djeynabou, Ndiaye, Moustapha, and Diop, Amadou Gallo
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- *
UNIVERSITY hospitals , *ELECTROENCEPHALOGRAPHY , *OLDER people - Published
- 2023
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37. Continuous spike and waves during slow sleep in the Neurological Department of Fann National University Hospital of Dakar: Topographic aspects and age.
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Seck, Lala Bouna, Sarr, Mamadou, Ka, Mamadou, Diop, Alassane Mamadou, Diop-Sene, Marème Soda, Gaye, Arame, Faye, Anna Modji Basse, Sow, Adjaratou Djeynabou, Ndiaye, Moustapha, and Diop, Amadou Gallo
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- *
SLOW wave sleep , *PUBLIC hospitals , *UNIVERSITY hospitals - Published
- 2023
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38. Impulse control disorders during Parkinson's disease in the neurological service of FANN University Hospital in Dakar.
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Seck, Lala Bouna, Sarr, Mamadou Moustapha, Fall, Maouly, Diop, Alassane Mamadou, Ndiaye, Moustapha, and Diop, Amadou Gallo
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- *
IMPULSE control disorders , *PARKINSON'S disease , *NEUROLOGICAL disorders , *UNIVERSITY hospitals - Published
- 2023
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39. Contribution of the sleep electroencephalogram in the diagnosis of epilepsy in children at the Ibrahima Pierre Ndiaye Neurological Clinic of Dakar, Senegal.
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Bassolé, Prisca-Rolande, Faye, Anna Modji Basse, Sow, Adjaratou Djeynabou, Damon, Michel-Arnaud Saphou, Gaye, Arame, Diop-Sene, Marème Soda, Seck, Lala Bouna, and Ndiaye, Moustapha
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- *
CHILDHOOD epilepsy , *CHILDREN with epilepsy , *DIAGNOSIS of epilepsy , *ELECTROENCEPHALOGRAPHY , *EPILEPSY , *SLEEP - Published
- 2023
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40. Measurement of cognition and profiling early learning environments in India, Indonesia and Senegal: a UKRI GCRF Action Against Stunting Hub protocol paper.
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Dockrell J, Massonnié J, Ang L, Munoz-Chereau B, Fernandez Rao S, Kolopaking R, Ndiaye M, and Heffernan C
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- Infant, Child, Pregnancy, Humans, Female, Child, Preschool, Indonesia epidemiology, Senegal epidemiology, Cognition, Observational Studies as Topic, Growth Disorders epidemiology, Growth Disorders etiology, Mothers education, Mothers psychology
- Abstract
Introduction: Childhood stunting is associated with poorer child health, growth and development including diminished cognitive abilities. Mapping out the links between child stunting and Early Childhood Education and Development is critical to increasing understanding of the causes and effects of childhood stunting, and for programme and policy development. The aim of this study is to investigate and compare the development and educational environments across India, Indonesia and Senegal, and to identify the multifactorial drivers and impacts of childhood stunting to inform a new typology., Methods and Analysis: This current study is part of an interdisciplinary observational research study, where women are recruited during pregnancy and mother-infant pairs followed prospectively, up to 24 months after birth. Eight measures will be used to profile children's early development and learning environments in two sample cohorts: (A) children aged 12 and 24 months born to the women recruited during pregnancy (ie, 500 pregnant mothers per country) and (B) a preschool case-control cohort of siblings from the main cohort aged between 3:6 and 5:6 years of age where anthropomorphic measures will be collected to assess degrees of stunting. Profiling of the development and learning environments in the countries will include both parent/caregiver self-reported and local staff (enumerators) direct assessments of children and settings., Ethics and Dissemination: This study was approved by the institutional ethics committees of all partner institutions. In India, Indian Council of Medical Research-National Institute of Nutrition, Hyderabad; In Indonesia, Ethics Committee of the Faculty of Medicine, University of Indonesia; and in Senegal, National Ethics Committee for Scientific Research in Senegal.The findings of the study will be disseminated in national and international meetings, seminars, conferences and peer-reviewed journals., Competing Interests: Competing interests: None., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ.)
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- 2024
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41. Surveillance of Viral Encephalitis in the Context of COVID-19: A One-Year Observational Study among Hospitalized Patients in Dakar, Senegal.
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Kahwagi J, Seye AO, Mbodji AB, Diagne R, Mbengue EH, Fall M, Andriamandimby SF, Easton A, Faye M, Fall G, Dia N, Ndiaye B, Ndiaye MB, Gueye A, Mbacke SS, Kane F, Ghouriechy MIE, Ensene Investigators, Seck LB, Gaye NM, Sall AA, Ndiaye M, Faye O, Diop AG, and Heraud JM
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- Adult, Humans, Prospective Studies, SARS-CoV-2, Senegal epidemiology, COVID-19 epidemiology, Encephalitis epidemiology, Encephalitis, Viral epidemiology, Viruses
- Abstract
The burden of encephalitis and its associated viral etiology is poorly described in Africa. Moreover, neurological manifestations of COVID-19 are increasingly reported in many countries, but less so in Africa. Our prospective study aimed to characterize the main viral etiologies of patients hospitalized for encephalitis in two hospitals in Dakar. From January to December 2021, all adult patients that met the inclusion criteria for clinical infectious encephalitis were enrolled. Cerebrospinal fluids, blood, and nasopharyngeal swabs were taken and tested for 27 viruses. During the study period, 122 patients were enrolled. Viral etiology was confirmed or probable in 27 patients (22.1%), with SARS-CoV-2 (n = 8), HSV-1 (n = 7), HHV-7 (n = 5), and EBV (n = 4) being the most detected viruses. Age groups 40-49 was more likely to be positive for at least one virus with an odds ratio of 7.7. The mortality was high among infected patients, with 11 (41%) deaths notified during hospitalization. Interestingly, SARS-CoV-2 was the most prevalent virus in hospitalized patients presenting with encephalitis. Our results reveal the crucial need to establish a country-wide surveillance of encephalitis in Senegal to estimate the burden of this disease in our population and implement strategies to improve care and reduce mortality.
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- 2022
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42. Are Sub-Saharan epileptic people less photosensitive? A Senegalese study of photoparoxysmal response in a reference epilepsy centre.
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Magnerou AM, Toffa DH, Sow AD, Basse A, Seck LB, Ndiaye M, and Diop AG
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- Adolescent, Adult, Africa South of the Sahara, Child, Child, Preschool, Electroencephalography methods, Epilepsy diagnosis, Epilepsy, Generalized complications, Epilepsy, Generalized epidemiology, Female, Humans, Infant, Male, Middle Aged, Photic Stimulation methods, Seizures epidemiology, Senegal epidemiology, Young Adult, Epilepsy complications, Epilepsy epidemiology, Photosensitivity Disorders epidemiology, Photosensitivity Disorders etiology
- Abstract
The photoparoxysmal response (PPR) is defined as the occurrence of generalized spike, spike-wave or polyspike-wave discharges consistently elicited by intermittent photic stimulation (IPS). PPR is not well studied in Sub-Saharan African people. We prospectively studied the epidemiological, clinical, and EEG characteristics of PPR among consecutive patients recorded at the clinical neurophysiology unit of Fann University Hospital (Dakar, Senegal). Among 6,808 EEG recordings including 3,065 pathological EEGs, we collected 56 EEGs with PPR (0.8% of all recorded EEGs and 1.8% of anormal EEGs), from 31 women and 25 men (sex ratio: 0.8). The mean age was 13.3 years (range: 8 months to 59 years). The peak of photosensitivity was found in the range of 6 to 10 years. Of the PPR cases, 12 had clinical manifestations during IPS. Generalized epilepsy was diagnosed in 23 (41%) patients and 18 (32%) had focal epilepsies. The most epileptogenic stimulation frequencies were between 12 and 24 Hz (range: 1-28 Hz). PPR were mainly triggered during eye closure (64%), and 41 patients (73% of PPR cases) were classified as Type 4 (Waltz classification). Our results confirm lower rates of photosensitivity in African Sub-Saharan people compared with others. Although the current data do not support a role of short-term ambient light levels, subject to consistent data from larger cohorts, it may be interesting to study the probable epigenetic-mediated protective role of sunshine against photosensitivity.
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- 2020
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43. Post-ivermectin encephalopathy in Senegal: a case report.
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Massi DG, Mansare ML, Traoré M, Ndiaye M, Diop AG, and Ndiaye MM
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- Adult, Antiparasitic Agents administration & dosage, Brain Diseases diagnosis, Humans, Ivermectin administration & dosage, Loiasis diagnosis, Male, Senegal, Antiparasitic Agents adverse effects, Brain Diseases etiology, Ivermectin adverse effects, Medication Errors
- Abstract
Ivermectin is an ant parasitic drug used for combating onchocerciasis and lymphatic filariasis. It works by inhibiting the function of neurons and muscles, thus causing paralysis of microfilariae. Side effects of this drug have been reported including post-ivermectin encephalopathy requiring emergency care in hospital. We report the case of a 35 years old patient living in rural areas of Senegal who presented two days after a mistake in administration of a second dose of ivermectin, headaches, altered consciousness and bilateral blindness. The workup revealed brain white matter lesions, abnormal liver function tests and biological inflammation without evidence of Loa loa microfilariae in blood and cerebrospinal fluid. Corticosteroid treatment was administered in emergency and patient recovered despite the persistence of bilateral blindness. Inflammatory process seems to have an important role in the pathophysiology of this encephalopathy. We should therefore carefully control the administration of this drugs.
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- 2017
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