Search

Your search keyword '"Monica P. Islam"' showing total 4 results
Start Over Author "Monica P. Islam" Language english
4 results on '"Monica P. Islam"'

1. The separation of pygopagus conjoined twins with fused spinal cords and imperforate anus

Author

Barrett P. Cromeens, Jeffrey R. Leonard, Lance S. Governale, Richard E. Kirschner, Gregory D. Pearson, Marc A. Levitt, Richard J. Wood, Rajan K. Thakkar, Monica P. Islam, Jennifer L. Mckinney, Emmett E. Whitaker, Jason A. Bryant, Brent H. Adler, William C. Ray, Brad Hoehne, and Gail E. Besner

Subjects
Conjoined twins, Pygopagus, 3D printing, Pediatrics, RJ1-570, Surgery, RD1-811
Abstract

Each set of conjoined twins has specific anatomic features dictating unique challenges to separation. Overcoming these challenges requires creative solutions that necessitate interdisciplinary collaboration. We present a unique case of pygopagus conjoined twins with fused spinal cords, imperforate anus without fistula, and a single anal sphincter complex. Separation included the use of novel applications of 3D printing and neurophysiologic monitoring. The 3D print helped to clarify the complex anatomy and facilitate communication during planning sessions. The neurophysiologic monitoring helped to distinguish a plane of separation for the spinal cords as well as the shared anal sphincter. Implementing these technologies and thus successfully separating these twins safely required a multidisciplinary team that extended beyond clinical specialties.

Published
2016
Full Text
View/download PDF

2. Pediatric EEG and the COVID-19 Pandemic: Can We Develop a Safe Transition Pathway to Reopen Our Laboratories?—Phase 2

Author

Monica P. Islam, Jorge Vidaurre, and John R. Mytinger

Subjects
2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), medicine.diagnostic_test, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Clinical Neurology, Electroencephalography, Virology, Pediatrics, Perinatology and Child Health, Pandemic, medicine, Neurology (clinical), Pediatrics, Perinatology, and Child Health, business
Published
2020
Full Text
View/download PDF

3. Neurocutaneous Syndromes

Author

Monica P. Islam, E. Steve Roach, Monica P. Islam, and E. Steve Roach

Subjects
Nervous system--Diseases
Abstract

Neurocutaneous Syndromes provides the most updated and comprehensive resource on the disorders that lead to the growth of tumors in various parts of the body, those caused by the abnormal development of cells in an embryo and characterized by the presence of tumors in various parts of the body and eyes, including the nervous system, and by certain differences in the skin. The most common neurocutaneous syndromes include, neurofibromatosis, Sturge-Weber syndrome, tuberous sclerosis, ataxia-telangiectasia, and von Hippel-Lindau disease. Symptoms vary widely and while present early may not express until later in life. As molecular medicine and genetic science is continuing to impact our understanding of neurocutaneous syndromes, this book also includes the latest molecular and genetic science. - Provides a comprehensive coverage of neurocutaneous syndromes - Details the latest molecular and genetic science related to neurocutaneous syndromes - Presents a focused reference for clinical practitioners and the neuroscience, clinical neurology, and neurogenetics research communities - Includes updated sections on the latest molecular and genetic science

Published
2015

4. Improving the inter-rater agreement of hypsarrhythmia using a simplified EEG grading scale for children with infantile spasms

Author

Nicole Ryan, Shaun A. Hussain, Geoffrey L. Heyer, Monica P. Islam, John R. Mytinger, John Millichap, Anup D. Patel, and Jaime Dawn E. Twanow

Subjects
Male, Pediatrics, medicine.medical_specialty, Clinical Neurology, Fleiss' kappa, Electroencephalography, Audiology, Severity of Illness Index, Epilepsy, medicine, Humans, EEG, Retrospective Studies, medicine.diagnostic_test, Infantile spasms, Eeg analysis, Epileptic encephalopathy, BASED score, Infant, West syndrome, medicine.disease, Brain Waves, Hypsarrhythmia, Inter-rater reliability, Electroencephalogram, Neurology, Child, Preschool, Female, Neurology (clinical), medicine.symptom, Psychology, Spasms, Infantile, Grading scale, Kappa
Abstract

Background There is poor inter-rater agreement in determining the presence or absence of hypsarrhythmia among patients with infantile spasms. Yet, remission of hypsarrhythmia has been used as a clinical and research outcome measure. Two important features of hypsarrhythmia are the burden of epileptiform discharges and the amplitudes of background slow waves. We hypothesized that an electroencephalogram (EEG) grading scale emphasizing epileptiform discharge burden and the amplitudes of background slow waves would improve inter-rater agreement in interpreting hypsarrhythmia. Our aim was to assess inter-rater agreement of hypsarrhythmia using a novel and simplified EEG grading scale called the ‘BASED' (Burden of Amplitudes and Epileptiform Discharges) score and compare this to the traditional method of EEG analysis. Methods Twenty patients with infantile spasms were prospectively evaluated and electroclinical outcomes were determined. Forty EEG clips (20 pre-treatment and 20 post-treatment), representing the most severely abnormal five minute sleep epoch of each study, were assessed by three reviewers blinded to treatment and clinical outcome. Fleiss' kappa ( К ) was used to assess the inter-rater agreement in the interpretation of hypsarrhythmia when using the BASED score compared to the traditional method of EEG analysis. Results Reviewers had favorable inter-rater agreement using the BASED score in interpreting hypsarrhythmia ( К : 0.87) compared to when using the traditional method of EEG analysis to interpret hypsarrhythmia ( К : 0.09). The three reviewers all agreed on the presence or absence of hypsarrhythmia in 37/40 (93%) epochs using the BASED score but in only 15/40 (38%) epochs using the traditional method of EEG analysis, p = Conclusion When compared to the traditional method of EEG analysis, the BASED score allowed for better inter-rater agreement in the interpretation of hypsarrhythmia. Future infantile spasms clinical trials must better define criteria for hypsarrhythmia.

Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results