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70 results on '"Moins‐Teisserenc, Helene"'

2. Real-life efficacy of immunotherapy for Sézary syndrome: a multicenter observational cohort study

Author

Bozonnat, Alizée, Beylot-Barry, Marie, Dereure, Olivier, D’Incan, Michel, Quereux, Gaëlle, Guenova, Emmanuella, Perier-Muzet, Marie, Dalle, Stephane, Grange, Florent, Viguier, Manuelle-Anne, Ram-Wolff, Caroline, Feldmeyer, Laurence, Beltraminelli, Helmut, Bonnet, Nathalie, Amatore, Florent, Maubec, Eve, Franck, Nathalie, Machet, Laurent, Chasset, François, Brunet-Possenti, Florence, Bouaziz, Jean-David, Battistella, Maxime, Donzel, Marie, Pham-Ledard, Anne, Bejar, Claudia, Moins-Teisserenc, Hélène, Mourah, Samia, Saiag, Philippe, Hainaut, Ewa, Michel, Catherine, Bens, Guido, Adamski, Henri, Aubin, François, Boulinguez, Serge, Joly, Pascal, Tedbirt, Billal, Templier, Isabelle, Troin, Laura, Montaudié, Henri, Ingen-Housz-Oro, Saskia, Faiz, Sarah, Mortier, Laurent, Dobos, Gabor, Bagot, Martine, Resche-Rigon, Matthieu, Montlahuc, Claire, Serret-Larmande, Arnaud, and de Masson, Adèle

Published
2024
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3. Allogeneic transplantation in advanced cutaneous T-cell lymphomas (CUTALLO): a propensity score matched controlled prospective study

Author

de Masson, Adèle, Beylot-Barry, Marie, Ram-Wolff, Caroline, Mear, Jean-Baptiste, Dalle, Stéphane, d'Incan, Michel, Ingen-Housz-Oro, Saskia, Orvain, Corentin, Abraham, Julie, Dereure, Olivier, Charbonnier, Amandine, Cornillon, Jérôme, Longvert, Christine, Barete, Stéphane, Boulinguez, Serge, Wierzbicka-Hainaut, Ewa, Aubin, François, Rubio, Marie-Thérèse, Bernard, Marc, Schmidt-Tanguy, Aline, Houot, Roch, Pham-Ledard, Anne, Michonneau, David, Brice, Pauline, Labussière-Wallet, Hélène, Bouaziz, Jean-David, Grange, Florent, Moins-Teisserenc, Hélène, Jondeau, Katayoun, Michel, Laurence, Mourah, Samia, Battistella, Maxime, Daguindau, Etienne, Loschi, Michael, Picard, Alexandra, Franck, Nathalie, Maillard, Natacha, Huynh, Anne, Nguyen, Stéphanie, Marçais, Ambroise, Chaby, Guillaume, Ceballos, Patrice, Le Corre, Yannick, Maury, Sébastien, Bay, Jacques-Olivier, Adamski, Henri, Bachy, Emmanuel, Forcade, Edouard, Socié, Gérard, Bagot, Martine, Chevret, Sylvie, Peffault de Latour, Régis, and de Latour, Régis Peffault

Published
2023
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4. Macrophage-derived CXCL9 and CXCL11, T-cell skin homing, and disease control in mogamulizumab-treated CTCL patients

Author

de Masson, Adèle, Darbord, Delphine, Dobos, Gabor, Boisson, Marie, Roelens, Marie, Ram-Wolff, Caroline, Cassius, Charles, Le Buanec, Hélène, de la Grange, Pierre, Jouenne, Fanélie, Louveau, Baptiste, Sadoux, Aurélie, Bouaziz, Jean-David, Marie-Cardine, Anne, Bagot, Martine, Moins-Teisserenc, Hélène, Mourah, Samia, and Battistella, Maxime

Published
2022
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5. Human-Derived α1-Antitrypsin is Still Efficacious in Heavily Pretreated Patients with Steroid-Resistant Gastrointestinal Graft-versus-Host Disease

Author

Giannoni, Livia, Morin, Florence, Robin, Marie, Peyneau, Marine, Schlageter, Marie Hélène, Desmier, Deborah, Pagliuca, Simona, Sutra Del Galy, Aurélien, Sicre de Fontbrune, Flore, Xhaard, Alienor, Dhedin, Nathalie, Moins-Teisserenc, Hélène, Peffault de Latour, Regis, Socié, Gerard, and Michonneau, David

Published
2020
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6. Real-life efficacy of immunotherapy for Sézary syndrome: a multicenter observational cohort study

Author

Bozonnat, Alizée, Beylot-Barry, Marie, Dereure, Olivier, D’Incan, Michel, Quereux, Gaëlle, Guenova, Emmanuella, Perier-Muzet, Marie, Dalle, Stephane, Grange, Florent, Viguier, Manuelle-Anne, Ram-Wolff, Caroline, Feldmeyer, Laurence, Beltraminelli, Helmut, Bonnet, Nathalie, Amatore, Florent, Maubec, Eve, Franck, Nathalie, Machet, Laurent, Chasset, François, Brunet-Possenti, Florence, Bouaziz, Jean-David, Battistella, Maxime, Donzel, Marie, Pham-Ledard, Anne, Bejar, Claudia, Moins-Teisserenc, Hélène, Mourah, Samia, Saiag, Philippe, Hainaut, Ewa, Michel, Catherine, Bens, Guido, Adamski, Henri, Aubin, François, Boulinguez, Serge, Joly, Pascal, Tedbirt, Billal, Templier, Isabelle, Troin, Laura, Montaudié, Henri, Ingen-Housz-Oro, Saskia, Faiz, Sarah, Mortier, Laurent, Dobos, Gabor, Bagot, Martine, Resche-Rigon, Matthieu, Montlahuc, Claire, Serret-Larmande, Arnaud, and de Masson, Adèle

Published
2025
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7. Safety of CD34+ Hematopoietic Stem Cells and CD4+ T Lymphocytes Transduced with LVsh5/C46 in HIV-1 Infected Patients with High-Risk Lymphoma

Author

Delville, Marianne, Touzot, Fabien, Couzin, Chloé, Hmitou, Isabelle, Djerroudi, Lounes, Ouedrani, Amani, Lefrère, François, Tuchman-Durand, Caroline, Mollet, Chloé, Fabreguettes, Jean-Roch, Ferry, Nicolas, Laganier, Laurent, Magnani, Alessandra, Magrin, Elisa, Jolaine, Valérie, Saez-Cirion, Asier, Wolstein, Orit, Symonds, Geoffrey, Frange, Pierre, Moins-Teisserenc, Hélène, Chaix-Baudier, Marie-Laure, Toubert, Antoine, Larghero, Jérôme, Parquet, Nathalie, Brignier, Anne C., Barré-Sinoussi, Françoise, Oksenhendler, Eric, and Cavazzana, Marina

Published
2019
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16. O-144 - Lacutamab in patients with mycosis fungoides: efficacy results according to updated lymph node classification in the TELLOMAK study

Author

Bagot, Martine, Kim, Youn H, Ortiz-Romero, Pablo L, Zinzani, Pier Luigi, Beylot-Barry, Marie, Dalle, Stéphane, Jacobsen, Eric, Combalia, Andrea, Huen, Auris, Mehta-Shah, Neha, Khodadoust, Michael, Mehta, Amitkumar, Dereure, Olivier, Battistella, Maxime, Gru, Alejandro, Moins-Teisserenc, Hélène, Viotti, Julien, Paiva, Christine, Boyer-Chammard, Agnès, and Porcu, Pierluigi

Published
2023
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22. CCR8 is a new therapeutic target in cutaneous T-cell lymphomas

Author

Giustiniani, Jérôme, Dobos, Gabor, Moins-Teisserenc, Hélène, Eustaquio, Tiago, Battistella, Maxime, Ortonne, Nicolas, Ram-Wolff, Caroline, Bouaziz, Jean-David, Marie-Cardine, Anne, Mourah, Samia, Bagot, Martine, Kupper, Thomas S., Clark, Rachael A., Bensussan, Armand, and de Masson, Adèle

Published
2022
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23. Patterns of Cytomegalovirus Reactivation Are Associated with Distinct Evolutive Profiles of Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation

Author

Moins-Teisserenc, Hélène, Busson, Marc, Scieux, Catherine, Bajzik, Véronique, Cayuela, Jean-Michel, Clave, Emmanuel, de Latour, Régis Peffault, Agbalika, Félix, Ribaud, Patricia, Robin, Marie, Rocha, Vanderson, Gluckman, Eliane, Charron, Dominique, Socié, Gérard, and Toubert, Antoine

Published
2008
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26. Lacutamab in Patients with Relapsed and Refractory Sèzary Syndrome: Results from the Tellomak Phase 2 Trial

Author

Bagot, Martine, Kim, Youn H., Geskin, Larisa J., Ortiz-Romero, Pablo L., Kim, Ellen, Mehta-Shah, Neha, Dereure, Olivier, Oro, Saskia, Beylot-Barry, Marie, Dalle, Stéphane, Jacobsen, Eric, Lansigan, Frederick, Ram-Wolff, Caroline, Khodadoust, Michael S, Battistella, Maxime, Gru, Alejandro A, Moins-Teisserenc, Hélène, Zinzani, Pier Luigi, Viotti, Julien, Paiva, Christine, Muller, Marianna, and Porcu, Pierluigi

Published
2023
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28. Flow cytometry for the assessment of blood tumour burden in cutaneous T‐cell lymphoma: towards a standardized approach.

Author

Vermeer, Maarten H., Moins‐Teisserenc, Helene, Bagot, Martine, Quaglino, Pietro, and Whittaker, Sean

Subjects
*SEZARY syndrome, *CUTANEOUS T-cell lymphoma, *T-cell receptor genes, *FLOW cytometry, *MYCOSIS fungoides, *NON-Hodgkin's lymphoma, *GENE rearrangement
Abstract

Mycosis fungoides (MF) and Sézary syndrome (SS) are the best‐studied subtypes of cutaneous T‐cell lymphoma, a rare non‐Hodgkin lymphoma that primarily presents in the skin but can also involve blood, lymph nodes and viscera. The role of blood involvement in the assessment and staging of MF and SS has evolved in recent years from being classed as simply 'present' or 'absent', with no impact on staging, to full analysis of abnormal peripheral blood T cells using flow cytometry (FC) to detect and quantify aberrant T‐cell phenotypes and polymerase chain reaction (PCR) to characterize T‐cell receptor gene rearrangements. These sensitive peripheral blood assessments are replacing manual Sézary cell counts and have become an important part of clinical workup in MF and SS, providing the potential for more accurate prognosis and appropriate management. However, although international recommendations now include guidelines for FC analysis of peripheral blood markers for staging purposes, many clinics only perform these analyses in patients with advanced‐stage lymphoma, if at all, and there is still a need for standardized use of validated markers. Standardization of a single effective multiparameter FC panel would allow for accurate identification and quantification of blood tumour burden for diagnosis, staging, assessment of therapeutic response, and monitoring of disease progression at all stages of disease. Once defined, validation of an MF/SS biomarker FC panel will enable uptake into clinical settings along with associated standardization of protocols and reagents. This review discusses the evolution of the role of FC in evaluating blood involvement in MF and SS, considers recently published international guidelines and identifies evidence gaps for future research that will allow for standardization of FC in MF and SS. [ABSTRACT FROM AUTHOR]

Published
2022
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29. Identification of multiple HLA-A*0201-restricted cruzipain and FL-160 CD8 + epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients

Author

Fonseca, Simone G., Moins-Teisserenc, Hélène, Clave, Emmanuel, Ianni, Bárbara, Nunes, Vera Lopes, Mady, Charles, Iwai, Leo K., Sette, Alessandro, Sidney, John, Marin, Maria Lúcia C., Goldberg, Anna Carla, Guilherme, Luiza, Charron, Dominique, Toubert, Antoine, Kalil, Jorge, and Cunha-Neto, Edecio

Published
2005
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30. Lacutamab in Patients with Advanced Sezary Syndrome: Results from an Interim Analysis of the Tellomak Phase 2 Trial

Author

Bagot, Martine, Kim, Youn H., Ortiz-Romero, Pablo L., Zinzani, Pier Luigi, Mehta-Shah, Neha, Dereure, Olivier, Beylot-Barry, Marie, Dalle, Stéphane, Jacobsen, Eric D, Huen, Auris, Combalia, Andrea, Battistella, Maxime, Gru, Alejandro A., Moins-Teisserenc, Hélène, Khodadoust, Michael S., Viotti, Julien, Paiva, Christine, Muller, Marianna, and Porcu, Pierluigi

Published
2022
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34. Tre-O2-05 - Macrophage-derived CXCL9 and CXCL11 recruit CD8 T cells in skin and provide long-term disease control in mogamulizumab-treated CTCL patients

Author

de Masson, Adèle, Darbord, Delphine, Dobos, Gabor, Boisson, Marie, Roelens, Marie, Ram-Wolff, Caroline, Cassius, Charles, Le Buanec, Hélène, de la Grange, Pierre, Jouenne, Fanélie, Louveau, Baptiste, Sadoux, Aurélie, Bouaziz, Jean-David, Marie-Cardine, Anne, Bagot, Martine, Moins-Teisserenc, Hélène, Mourah, Samia, and Battistella, Maxime

Published
2021
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35. Tre-O2-07 - Lacutamab in patients (pts) with advanced mycosis fungoides (MF) according to KIR3DL2 expression: early results from the TELLOMAK phase 2 trial

Author

Bagot, Martine, Kim, Youn, Zinzani, Pier Luigi, Dalle, Stephane, Beylot-Barry, Marie, Ortiz-Romero, Pablo L, Cambalia, Andrea, Dereure, Olivier, Mortier, Laurent, Jacobsen, Eric, Battistella, Maxime, Gru, Alejandro, Moins-Teisserenc, Hélène, Paiva, Christine, Boyer-Chammard, Agnès, Rotolo, Federico, Azim, Hatem A., and Porcu, Pierluigi

Published
2021
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37. Bio-O1-01 - Diagnostic performance of high throughput sequencing of the T-cell receptor beta gene for the diagnosis of cutaneous T-cell lymphoma

Author

de Masson, Adele, Zimmermann, Clement, Boisson, Marie, Ram-Wolff, Caroline, Sadoux, Aurélie, Louveau, Baptiste, Vignon, Dominique, Rivet, Jacqueline, Cayuela, Jean-Michel, Dobos, Gabor, Moins-Teisserenc, Hélène, Roelens, Marie, Gruber, Aurélia, Lebbé, Céleste, Bagot, Martine, Battistella, Maxime, and Mourah, Samia

Published
2021
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42. Relationship between Toxoplasma gondii infection and bipolar disorder in a French sample

Author

Hamdani, Nora, Daban-Huard, Claire, Lajnef, Mohamed, Richard, Jean-Romain, Delavest, Marine, Godin, Ophélia, Guen, Emmanuel Le, Vederine, François-Eric, Lépine, Jean-Pierre, Jamain, Stéphane, Houenou, Josselin, Corvoisier, Philippe Le, Aoki, Masayuki, Moins-Teisserenc, Helene, Charron, Dominique, Krishnamoorthy, Rajagopal, Yolken, Robert, Dickerson, Faith, Tamouza, Ryad, and Leboyer, Marion

Published
2013
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45. DNA vaccination with all-trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model

Author

Furugaki, Kouichi, Pokorna, Katerina, Le Pogam, Carole, Aoki, Masayuki, Reboul, Murielle, Bajzik, Véronique, Krief, Patricia, Janin, Anne, Noguera, Marie-Elena, West, Robert, Charron, Dominique, Chomienne, Christine, Pla, Marika, Moins-Teisserenc, Hélène, and Padua, Rose Ann

Published
2010
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46. Newly-Generated Regulatory B- and T-Cells Are Associated with Clinical Improvement and Reversal of Dermal Fibrosis in Systemic Sclerosis Patients after Autologous Hematopoietic Stem Cell Transplantation

Author

Arruda, Lucas C M, Lima-Júnior, João R, Clave, Emmanuel, Moraes, Daniela A, Douay, Corinne, Fournier, Isabelle, Moins-Teisserenc, Hélène, Covas, Dimas Tadeu, Malmegrim, Kelen, Farge, Dominique, Ramalho, Leandra, Toubert, Antoine, and Oliveira, Maria Carolina

Published
2016
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47. Long-term immune reconstitution and T cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients.

Author

Farge, Dominique, Arruda, Lucas C. M., Brigant, Fanny, Clave, Emmanuel, Douay, Corinne, Marjanovic, Zora, Deligny, Christophe, Maki, Guitta, Gluckman, Eliane, Toubert, Antoine, and Moins-Teisserenc, Helene

Subjects
T cells, SYSTEMIC scleroderma, HEMATOPOIETIC stem cell transplantation, IMMUNE reconstitution inflammatory syndrome, B cells
Abstract

The determinants of clinical responses after autologous hematopoietic stem cell transplantation (aHSCT) in systemic sclerosis (SSc) are still unraveled. We analyzed long-term immune reconstitution (IR) and T cell receptor (TCR) repertoire diversity in 10 SSc patients, with at least 6 years simultaneous clinical and immunological follow-up after aHSCT. Patients were retrospectively classified as long-term responders (A, n = 5) or non-responders (B, n = 5), using modified Rodnan's skin score (mRSS) and forced vital capacity (FVC%). All patients had similar severe SSc before aHSCT. Number of reinjected CD34+ cells was higher in group B versus A (P = 0.02). Long-term mRSS fall >25% was more pronounced in group A (P = 0.004), the only to improve long-term FVC% >10% (P = 0.026). There was an overall trend toward increased of T cell reconstitution in group B versus A. B cells had a positive linear regression slope in group A (LRS = 11.1) and negative in group B (LRS = -11.6). TCR repertoire was disturbed before aHSCT and the percentage of polyclonal families significantly increased at long-term (P = 0.046), with no difference between groups. Despite improved skin score after aHSCT in all SSc patients, pretransplant B cell clonal expansion and faster post-transplant T cell IR in long-term non-responder/relapsing patients call for new therapeutic protocols guided by IR analysis to improve their outcome. [ABSTRACT FROM AUTHOR]

Published
2017
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49. Lenalidomide consolidation and maintenance therapy after autologous stem cell transplant for multiple myeloma induces persistent changes in T-cell homeostasis.

Author

Clave, Emmanuel, Douay, Corinne, Coman, Tereza, Busson, Marc, Bompoint, Caroline, Moins-Teisserenc, Helene, Glauzy, Salomé, Carmagnat, Maryvonnick, Gorin, Norbert Claude, Toubert, Antoine, and Garderet, Laurent

Subjects
HEALTH outcome assessment, MULTIPLE myeloma treatment, CANCER chemotherapy, STEM cell transplantation research, IMMUNOLOGICAL adjuvants, IMMUNOMODULATORS, T cells, HOMEOSTASIS
Abstract

Whether the efficacy of lenalidomide in the treatment of multiple myeloma (MM) is due to direct tumor toxicity only or to additional immunomodulatory effects is unclear. We studied the effect of lenalidomide treatment on T-cell immune reconstitution in patients with MM who had undergone autologous peripheral blood stem cell transplant (ASCT). Twenty-nine newly diagnosed patients with MM received induction therapy followed by high-dose melphalan and ASCT. After ASCT, 11 patients received lenalidomide consolidation therapy for 2 months followed by maintenance therapy until disease progression. The remaining 18 patients received no treatment. Serial analysis of thymic output, as given by numbers of T-cell receptor excision circles (sjTRECs), and T-cell phenotyping was performed until 18 months post-ASCT. Lenalidomide impaired long-term thymic T-cell reconstitution, decreased CD4 + and CD8 + CD45RA + CCR7 − effector-terminal T-cell absolute counts and increased CD4 + CD25 + CD127 − /low regulatory T-cells. Lenalidomide consolidation and long-term maintenance therapy, administered post-ASCT, may have a potentially negative impact on immune surveillance. [ABSTRACT FROM AUTHOR]

Published
2014
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50. DNA Vaccination and All-Trans Retinoic Acid Treatment-Induced Long Term Survival Requires CD4+ and CD8+ T-Cell Activation in An APL Mouse Model.

Author

Padua, Rose Ann, Furugaki, Kouichi, Moins-Teisserenc, Helene, Pokorna, Katerina, Le Pogam, Carole, Reboul, Murielle, Aoki, Masayuki, Bajzik, Veronique, Krief, Patricia, Janin, Anne, Noguera, Maria-Elena, West, Robert, Schlageter, Marie-Helene, Charron, Dominique, Pla, Marika, and Chomienne, Christine

Published
2008
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